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Myogenic Autoregulation of Coronary Vessels and Heterometric Autoregulation of the Myocardium
Doring, H.J., Schlicht, I., Hiller, V., Jiang, X.R. 대한생리학회 대한생리학회지 12 Pages
대한생리학회 대한생리학회지 1989, 제 23권 제 2호 1 225-236 (12 pages)
~ 190 mmHg. SHR only showed higher developed left ventricular pressures as compared with NR. The lower part of the figure shows the respective pressure-flow curves of the coronary vessels. Here, too, significant differences between the different groups of animals were found. For example the autoregulatory range of the rat coronary vessels is in the range of 90 to 190 mmHg. The slope of both... of the coronary vessels were induced by means of stepwise increases of perfusion pressure. 2) According to this loading test Frank-Starling function curves of the left ventricle and pressure-flow curves of the coronary vessels can be drawn. This graphic evaluation gives more information about the condition of the heart and the coronary vessels than simple evaluation under hemodynamic equilibrium. 3) There are significant differences in both curves between animal species and between different... -
Multidetector computed tomographic angiography evaluation of micropig major systemic vessels for xenotransplantation
Jung Min Ryu, Woong Yoon, Jae Hong Park, Seung Pil Yun, Min Woo Jang, Ho Jae Han* 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2011, 제 12권 제 3호 2 209-214 (6 pages)
M, Gedikli O, Acar G, Ergene O. The diameters of the aorta and its major branches in patients with isolated coronary artery ectasia. Tex Heart Inst J 2006, 33, 463-468. 17. Kamel IR, Kruskal JB, Warmbrand G, Goldberg SN, Pomfret EA, Raptopoulos V. Accuracy of volumetric measurements after virtual right hepatectomy in potential donors undergoing living adult liver transplantation. AJR Am J... the major systemic vessels in micropigs and compared our results to published human data. The main vasculature of the animals was similar to that of humans, except for the iliac arterial system. However, diameters of the major systemic vessels were significantly different between micropigs and humans. Specifically, the diameter of the aortic arch, abdominal aorta, external iliac artery, and femoral artery, were measured as 1.50 ± 0.07 cm, 0.85 ± 0.06 cm, 0.52 ± 0.05 cm, and 0.48... -
The Alteration of Ca2+-activated K+ Channels in Coronary Arterial Smooth Muscle Cells Isolated from Isoproterenol-induced Cardiac Hypertrophy in Rabbit
NariKim, JinHan, EuiyongKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.2 5 147-156 (10 pages)
also initiate or aggravate pathophysiological states such as vasospasm and ischemia (Brayden & Nelson， 1992) In conclusion， these aJterations of Kc， channels may be involved in reduced coronary reserve in isoproterenol-induced cardiac hypertrophy. Therefore， to further determine the role that these alteration of Kca channels may change in coronarγ blood fow， experiments either in... amplitudes and the slope conductance of coronary KCa channels were decreased without changes of the channel kinetics in isoproterenol-induced cardiac hypertrophy; (2) the sensitivity of coronary KCa channels to the changes of intracellular concentration of Ca2 was reduced in isoproterenol-induced cardiac hypertrophy. From above results, we suggest for the first time that the alteration of KCa channels are involved in impaired coronary reserve in isoproterenol-induced cardiac hypertrophy. -
Altered Delayed Rectifier K+ Current of Rabbit Coronary Arterial Myocytes in Isoproterenol-Induced Hypertrophy
NariKim, JinHan, EuiyongKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.1 5 33-40 (8 pages)
retur toward norma1 in vascu1ar density in both the capillary bed and the in tramyocardia1 vessels in chronic models of cardiac hypertrophy in the rat and the dog (Wang1er et a1， 1982; Peters et a1， 1984; Tomanek et a1， 1989) and no transmura1 differences in vascu1ar morpho1ogy in chronic moderately severe 1ef ventricu1ar hypertrophy in the dog (Bishop et a1， 1996). These controversia1... normal and hypertrophied hearts. These channels were measured from rabbit coronary smooth muscle cells using a patch clamp technique. The main findings of the study are as follows: (1) the KDR current density was decreased without changes of the channel kinetics in isoproterenol-induced hypertrophy; (2) the sensitivity of coronary KDR channels to 4-AP was increased in isoproterenol-induced hypertrophy. From the above results, we suggest for the first time that the alteration of KDR channels may... -
Effects of Calcium Channel Blockers on Porcine Cardiac and Coronary Arterial Function in Ischemia-Reperfusion
YungHongBaik, HyunKook, SunHeePark, SeongJooJeong, DongYoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.6 7 587-595 (9 pages)
1103， 1992 Ma1suda H， Dawaguchi A， Tamai J， Uematsu M. Nagata S， Miyatake K. Attenuated inhibition of adrenergic contraction by nitric oxide in injured guinea pig femoral artery. Heart Vessels 12: 10 - 18 ， 1997 Mattson MP， Cheng B. Growth factors protec‘ neurons against excitolOxicfischemk damage by stab ilizin g ca1cium homeotasis. Slroke 24: 1136-1140， 1993 Mehta JL， N ich ols... right coronary artery (RCA) induced by ischemia- reperfusion in anesthetized, open-chest pigs. After reperfusion, pigs were sacrificed and the RCA was rapidly dissected for in vitro experiments. Experimental groups were divided into 4 groups: control (C-RCA), ischemia-reperfusion only (I-RCA), verapamil infusion (VI-RCA) and nifedipine infusion (NI-RCA) group, respectively. The ischemia did not affect hemodynamics, mean arterial pressure, heart rate, LVdP/dtmax, and decreased RCA flow. Arterial... -
Effects of the Endothelium on the Contractile Responses to Norepinephrine in Isolated Proximal and Distal Coronary Artery of Pigs
Kim, Jong-Hoon, Jeon, Byeong-Hwa, Chang, Seok-Jong, Park, Hae-Kun 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1993, 제 27권 제 1호 3 27-36 (10 pages)
NE on en- dothelium in small intramural resistance arteries in the coronary circulation is lacking. Recently, Nyborg (I 990) reported that NE could release EDRF in only the proximal part of rat coronary artery. In several blood vessels, the endothelium attenuates the vasoconstriction caused by NE (Carrier & White, 1985), cloni- dine (Egleme et al, 1984), and phenylephrine (Carrier & White,... 10-6M). α-adrenoceptor-mediated contraction by NE was greater in the proximal coronary artery than the distal coronary artery. Quantitatively, α1-adrenoceptor mediated contraction by NE was greater than α2-adrenoceptor mediated contraction by NE in both arteries. NE-induced relaxation was decreased by rubbing of endothelium in both arteries. α1-and α2-adrenoceptor mediated contraction by NE were potentiated by rubbing of endothelium in both arteries. Pretreatment with methylene blue, an... -
Effects of pH, PCO2, and Adenosine on the Contractility of Pig Coronary Artery
Chang, Seok-Jong, Kim, Il-Seon, Jeon, Byeong-Hwa, Kim, Se-Hoon 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1992, 제 26권 제 1호 5 45-54 (10 pages)
by low coronary blood flow, hypoxia, or increased metabolic ac- tivity of the heart lead to the myocardial for- matiop. of adenosine, which crosses the interstitial fluid space to reach the coronary resistance vessels and induce vasodilation via activating an adenosine receptor. However, it is little known that the interrelation between adenosine-induced relaxation and the change of... on the vascular contractility were investigated in the pig coronary arteries. The helical strips of isolated coronary arteries were immersed in the HEPES or HCO3-/CO2-buffered Tyrode s solution equilibrated with 100% O2 or 95% O2-5% CO2 at 35℃. The contraction was recorded isometrically using a force transducer. The amplitudes of contraction induced by ACh, high K+, and electrical Held stimulation (EFS) were decreased by elevating extracellular pH (pHo) and were increased by lowering pHo. A... -
Technique of Coronary Transfer for TGA with Single Coronary Artery
Kim. Tae Ho, Jung. Jae Jun, Kim. Yong Han, Yang. Ji-Hyuk, Jun. Tae-Gook 대한흉부외과학회 The Korean journal of thoracic and cardiovascular surgery 4 Pages
대한흉부외과학회 The Korean journal of thoracic and cardiovascular surgery 2014, Vol.47 No.6 529-532 (4 pages)
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Relation of Pulmonary Function Impairment and Coronary Artery Calcification by Multi-detector Computed Tomography in Group Exposed to Inorganic Dusts
Lee. Won-Jeong, Shin. Jae Hoon, Park. So Young 대한결핵및호흡기학회 Tuberculosis and respiratory diseases : TRD 7 Pages
대한결핵및호흡기학회 Tuberculosis and respiratory diseases : TRD 2013, Vol.74 No.2 56-62 (7 pages)
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Pharmacological Evidence that Cromakalim Inhibits Ca2+ Release from Intracellular Stores in Porcine Coronary Artery
ByungYongRhim, SunHwaHong, ChiDaeKim, WonSukLee, KiWhanHong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.1 4 27-34 (8 pages)
and Kuriyama H Inositol 1，4，5-triphosphate release Ca'+ fom intracel lular storc sitcs in skinncd singlc cclls of porcinc coronary artcry. Biochem Biαph싸 Rα Commun 120 481-485，1984 Weir SW and Weston AH. The effects of BRL34915 and !l1corandi1 on electrical and mechanical activity and on 8R Rb efflux in rat blood vessels. Br J Pharmacol 88 121-128， 1986 Yamagishi T， Yanagisawa T... In the present study, it was aimed to further indentify the intracellular action mechansm of cromakalim and levcromakalim in the porcine coronary artery. In intact porcine coronary arterial strips loaded with fura-2/AM, acetylcholine caused an increase in intracellular free Ca2 ([Ca2]i) in association with a contraction in a concentration-dependent manner. Cromakalim (1 ㄍM) caused a reduction in acetylcholine-induced increased [Ca2]i not only in the mormal...