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Ectopic EBP2 expression enhances cyclin E1 expression and induces chromosome instability in HEK293 stable clones
Lee. Ming-Cheng, Hsieh. Chang-Hsun, Wei. Shu-Chen, Shen. Shu-Chen, Chen. Chiung-Nien, Wu. Vin-Cent, Chuang. Li-Ying, Hsieh. Fon-Jou, Wu. 생화학분자생물학회 BMB reports 6 Pages
생화학분자생물학회 BMB reports 2008, Vol.41 No.10 716-721 (6 pages)
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Pyrethroid insecticides, lambda-cyhalothrin and cyperemthrin, caused thegrowth of ovarian cancer cells expressing estrogen receptor via estrogenreceptor pathway
Cho Won Kim, Kyung Chul Choi 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 297 496-497 (2 pages)
that JEG-3 cell proliferationwas significantly inhibited by all CSEs, 3R4F and two-domestic cigarettes, in adose-dependent manner. Moreover, Western blot analysis revealed increasedcyclin D1 and cyclin E1 and decreased p21 and p27 by these CSE in JEG-3 cells. Increasedmigration or invasion ability of JEG-3 cells following CSE treatments was alsoconfirmed by a scratch or fibronectin invasion... -
Alterations of cell cycle, cell migration and endocrine activity wereinduced by cigarette smoke extracts in JEG-3 human placental cells
Cho Won Kim, Kyung Chul Choi 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 296 496-496 (1 pages)
that JEG-3 cell proliferationwas significantly inhibited by all CSEs, 3R4F and two-domestic cigarettes, in adose-dependent manner. Moreover, Western blot analysis revealed increasedcyclin D1 and cyclin E1 and decreased p21 and p27 by these CSE in JEG-3 cells. Increasedmigration or invasion ability of JEG-3 cells following CSE treatments was alsoconfirmed by a scratch or fibronectin invasion... -
A potentsubstance, progesterone suppresses epithelial- mesenchymal transition of ovariancancer cells via regulation of transcription factor which was induced byestrogen
So Ye Jeon, Kyung Chul Choi 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 295 495-496 (2 pages)
that JEG-3 cell proliferationwas significantly inhibited by all CSEs, 3R4F and two-domestic cigarettes, in adose-dependent manner. Moreover, Western blot analysis revealed increasedcyclin D1 and cyclin E1 and decreased p21 and p27 by these CSE in JEG-3 cells. Increasedmigration or invasion ability of JEG-3 cells following CSE treatments was alsoconfirmed by a scratch or fibronectin invasion... -
Retrospective study in cattle abortions submitted to the QIA, 2002~2015
Si Yeon Yang, Eun Jin Choi, Kyung Hyun Lee, Hyun Kyoung Lee, Yeon Hee Kim, Ha Young Kim, Byung Jae So 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 355 385-386 (2 pages)
a dose-dependent manner. The protein expressions of cyclin D1 and E1 were decreased while the protein expressions of p21 and p27 were increased by treatments with BaP and AN for 48 h. In DCF-DA assay, ROS level was increased by each treatment with BaP and AN for 48 h. In addition, it was confirmed by western blot assay that each exposure of BaP or AN to JEG-3 and BeWo cells for 4 h promoted... -
Treatment with cigarette smoke components altered the cell proliferation, apoptosis in human choriocarcinoma cancer cell lines via ROS-induced ER-stress pathway
Soo Min Kim, Hae Miru Lee, Kyung Chul Choi 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 354 385-385 (1 pages)
a dose-dependent manner. The protein expressions of cyclin D1 and E1 were decreased while the protein expressions of p21 and p27 were increased by treatments with BaP and AN for 48 h. In DCF-DA assay, ROS level was increased by each treatment with BaP and AN for 48 h. In addition, it was confirmed by western blot assay that each exposure of BaP or AN to JEG-3 and BeWo cells for 4 h promoted... -
Cigarettesmoke impaired maturation of ovarian follicle and abnormal growth of uterus innerwall via changed expression of estrogen receptors and cell cycle arrest proteinp21 in female rats
Hae Miru Lee, Cho Won Kim, Kyung Chul Choi 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 353 384-385 (2 pages)
a dose-dependent manner. The protein expressions of cyclin D1 and E1 were decreased while the protein expressions of p21 and p27 were increased by treatments with BaP and AN for 48 h. In DCF-DA assay, ROS level was increased by each treatment with BaP and AN for 48 h. In addition, it was confirmed by western blot assay that each exposure of BaP or AN to JEG-3 and BeWo cells for 4 h promoted... -
Ethanol Elicits Inhibitory Effect on the Growth and Proliferation of Tongue Carcinoma Cells by Inducing Cell Cycle Arrest
Thanh-DoLe, ThiAnhThuDo, RinaYu, HoonYoo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.3 1 153-158 (6 pages)
such as cyclins and cyclin-dependent pro- tein kinases. The cells were treated with various doses of ethanol (0, 0.25, 0.5, 0.75, 1.0 and 1.5%) for 24 h and lysated for Western blotting. Cylin A, Cyclin E1 and Cyclin B1 were suppressed as the dose of etha nol in the medium increased (Fig. 4A). Band intensities of Cyclin A, Cyclin E1 and Cyclin B1 were gradually decreased in the concentration... 0 to 1.5% whilst the cell cycle regulators, cdk1, cdk2, and cdk4 as well as Cyclin A, Cyclin B1 and Cyclin E1, were gradually down-regulated. Flow cytometric analysis of cell cycle distribution revealed that YD-15 cells exposed to 1.5% ethanol for 24 h was mainly arrested at G2/M phase. However, ethanol induced apoptosis in YD-15 cells exposed to 2.5% or higher percent of ethanol. The cleaved PARP, a marker of caspase-3 mediated apoptosis, and the activation of caspase-3 and -7 were detected by... -
Role of Shc and Phosphoinositide 3-Kinase in Heregulin-Induced Mitogenic Signaling via ErbB3
MyongSooKimJohnG.Kol 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.6 9 497-506 (10 pages)
ro1e of PI3 kinase and p38 MAP kinase pathways Oncogene 18: 3440-3451， 1999 Dieh1 JA， Cheng M， Rousse1 MF， Sherr CJ. G1ycogen synthase kinase-3beta reg띠ates cyclin D1 proteo1ysis and subcellular localization. Genes Devel 12: 3499 3511， 1998 Duckworth BC， Cant1ey LC. Conditional inhibition of the mitogen-activated protein kinase cascade by wortman nin. Dependence on signal strength.... cyclin D1 expression by preteatment with MAPK kinase inhibitor or PI 3-kinase inhibitor before stimulation with heregulin. In accordance with the cyclin D1 expression, elimination of either Shc binding or PI 3-kinase binding reduced the heregulin-induced DNA synthesis and cell growth rate. Our results obtained by the comparison of wild-type and ErbB3 mutants indicate that the full induction of the cell cycle progression through G1/S phase by ErbB3 activation is dependent on both Shc/MAPK and PI...