자료유형
발행기관
- 대한수의학회(64)
- 대한생리학회-대한약리학회(57)
- 한국식물병리학회(34)
- 대한약리학회(9)
- 대한생리학회(6)
- 대한신경정신의학회(2)
- 한국기초간호학회(2)
- 한국교육정치학회(1)
- 한국동물번식학회(1)
- 한국동물학회(1)
- 한국수정란이식학회(1)
- 한국습지학회(1)
- 한국식품과학회(1)
- 한방비만학회(1)
간행물
- THE KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY(57)
- JOURNAL OF VETERINARY SCIENCE(46)
- THE PLANT PATHOLOGY JOURNAL (32)
- KOREAN JOURNAL OF VETERINARY RESEARCH(구 대한수의학회지)(11)
- 대한약리학잡지(9)
- 대한수의학회 학술대회발표집(7)
- 대한생리학회지(6)
- JOURNAL OF KOREAN BIOLOGICAL NURSING SCIENCE(2)
- 식물병연구(2)
- 신경정신의학(2)
- FOOD SCIENCE AND BIOTECHNOLOGY(1)
- REPRODUCTIVE & DEVELOPMENTAL BIOLOGY(1)
- 교육정치학연구(1)
- 대한한방비만학회지(1)
- 동물학회지(1)
- 한국수정란이식학회지(1)
- 한국습지학회지(1)
전체 선택해제
총 181건 검색
본문검색 결과만 보기
-
Inhibitory Effects of Exogenous Recombinant Human Thioredoxin-1 to the Hepatic Cell Death caused by Acetaminophen-induced Free Radicals
Byung Woo Lee, Jin Woo Oh, Byoung O O, Sang Uk Nham, Byung Il 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 316 507-507 (1 pages)
Supplement 507 P-234 Inhibitory Effects of Exogenous Recombinant Human Thioredoxin-1 to the Hepatic Cell Death caused by Acetaminophen-induced Free Radicals Byung-Woo Lee 1 , Jin-Woo Oh 1 , Byoung-O O 2 , Sang-Uk Nham 2 , Byung Il *1 1 College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon 200-701, Republic of Korea; 2... -
Gintonin, an exogenous ginseng-derived LPA receptor ligand, promotes corneal wound healing
Hyeon-Joong Kim, Joon Young Kim, Byung-Hwan Lee, Sun-Hye Choi, Hyewon Rhim, Hyoung-Chun Kim, Seoung-Yob Ahn, Soon-Wuk Jeong, Min 대한수의학회 Journal of Veterinary Science 11 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 3호 16 387-397 (11 pages)
and reproduction in any medium, provided the original work is properly cited. pISSN 1229-845X eISSN 1976-555X Gintonin, an exogenous ginseng-derived LPA receptor ligand, promotes corneal wound healing Hyeon-Joong Kim 1, , Joon Young Kim 2, , Byung-Hwan Lee 1 , Sun-Hye Choi 1 , Hyewon Rhim 3 , Hyoung-Chun Kim 4 , Seoung-Yob Ahn 2, Soon-Wuk Jeong 2, Minhee Jang 5, Ik-Hyun Cho 5, Seung-Yeol Nah 1,*... Ginseng gintonin is an exogenous ligand of lysophosphatidic acid (LPA) receptors. Accumulating evidence shows LPA helps in rapid recovery of corneal damage. The aim of this study was to evaluate the therapeutic efficacy of gintonin in a rabbit model of corneal damage. We investigated the signal transduction pathway of gintonin in human corneal epithelium (HCE) cells to elucidate the underlying molecular mechanism. We next evaluated the therapeutic effects of gintonin, using a rabbit model of... -
Expression of Angiostatin Using DNA - Based Semliki Forest Virus Replicon
Hyun Soo Kim, Kwang Soon Shin, Jong Soo Lee, Young Ki Choi, Chul Joong Kim, Yong Soo Choi 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 1호 7 41-45 (5 pages)
using the v e c t o r s s u c h a s t h e S F V - d e r i v e d D N A v e c t o r d e s c r i b e d h e r e which expresses the foreign gene efficiently. A major advantage of the SFV-derived plasmid DNA vector is a high-level expression of exogenous gene using the self-amplifying systems of SFV. In addition, this vector is Fig. 2. Immunocytochemistry of angiostatin expressed in BHK-21 cells. Cells... we constructed the SFV-derived DNA vector by employing the cytomegalovirus immediate early enhancer/ promoter (CMV). This vector makes it possible to transfect the cells with DNA without the in vitro transcription process. The C-myc epitope and polyhistidine residue sequences were placed in downstream of the angiostatin gene to make it eligible to detect the expressed protein. The murine Ig k-chain V-J2-C signal sequence was placed in upstream to secrete the expressed protein from the cells. We... -
Ser1778 of 53BP1 Plays a Role in DNA Double-strand Break Repairs
Jung-HeeLee, Hyang-MinCheong, Mi-YoungKang, Sang-YoungKim, YoonsungKang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.5 2 343-348 (6 pages)
that can occur within the cell, the most dangerous is the DNA dou- ble-strand break (DSB); as little as one unrepaired DSB can be sufficient to kill a cell. These DSBs result from exposure to exogenous agents including ionizing radiation (IR) and certain chemotherapeutic drugs, from endoge- nously generated reactive oxygen species, and from mecha- nical stress on the chromosomes. When DSBs... the BRCT domain of 53BP1 in DNA repair. From our data, we were able to detect differences in the phosphorylation patterns in Ser25 and Ser1778 of 53BP1 after neocarzinostatin-induced DNA damage. Furthermore, the foci formation patterns in both phosphorylation sites of 53BP1 also evidenced sizeable differences following DNA damage. From our results, we concluded that each phosphoryaltion site of 53BP1 performs different roles, and Ser1778 is more important than Ser25 in the process of DNA repair. -
Effects of Exogenous ATP on Calcium Mobilization and Cell Proliferation in C6 Glioma Cell
Eun-JungLee, SeokHoCha, WoonKyuLee, Kweon-HaengLee, Sang-BokLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 3 419-425 (7 pages)
of exogenous ATP in glial cells. Extra cellular A TP induces stellation and increases glial fibrillary acidic protein content and DNA synthesis. It also modulates cell proliferation in primarily cultured astrocytes of neonatal rat cortices and rat striatum (Dubyak， 1991). In addition， extracellular ATP induces intracellular fee calcium mobilization in adult and immortalized Schwan cells... To clarify the effect of extracellular ATP in cultured C6 glioma cells, ATP-induced cytosolic free calcium ([Ca2]i) mobilization and cell proliferation were investigated. ATP-induced [Ca2]i increased in a dose-dependent manner (107 M∼103 M). ATP-induced [Ca2]i increases were slightly slowed in extracellular calcium-free conditions especially in sustained phase. ATP-induced [Ca2]i increment was also inhibited by the pretreatment of U73122, a... -
Reduction of TNFα-induced Oxidative DNA Damage Product, 8-Hydroxy-2′-Deoxyguanosine, in L929 Cells Stably Transfected with Small Heat Shock Protein
Young-MeePark, Eun-MiChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 11 209-219 (11 pages)
cells overexpressing exogenous small hsp. We also found that the cell killing activity of TNF α was decreased in these cells as measured by c1onogenic surviva1. Taken together， results fom the current study show that cytotoxic mechanism of TNF α involves oxidative damage of DNA and that overexpression of the small hsp reduces this oxidative damage. We suggest that the reduction of oxidative... markers of oxidative DNA damage. Our results clearly demonstrated that the level of 8 ohdG increased in L929 cells in a TNFα dose-dependent manner. Subsequently, we asked whether small HSP has a protective effect on TNFα-induced oxidative DNA damage. To accomplish this goal, we have stably transfected L929 cells with mouse small hsp cDNA (hsp25) since these cells are devoid of endogenous small hsps. We found that TNFα-induced 8 ohdG was decreased in cells overexpressing exogenous small hsp.... -
Dangyuja (Citrus grandis Osbeck) attenuates TPA- induced inflammation in mouse skin: possible role of anti-inflammatory agent
Jin hee Cho, So Jin Bing, KHINM Herath, A-reum Kim, Young heun Jee 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 317 507-508 (2 pages)
Supplement 507 P-234 Inhibitory Effects of Exogenous Recombinant Human Thioredoxin-1 to the Hepatic Cell Death caused by Acetaminophen-induced Free Radicals Byung-Woo Lee 1 , Jin-Woo Oh 1 , Byoung-O O 2 , Sang-Uk Nham 2 , Byung Il *1 1 College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon 200-701, Republic of Korea; 2... -
Anti-diabetic effect of Limonium tetragonum extract in high fat diet-fed C57BL/6J mice
Na Hyun Kim, Eun Ju Jeong, Tae Kil Tak, Seon Min Lee, Jung Il Choi, Jeong Doo Heo 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 311 504-505 (2 pages)
or detoxify exogenous chemicals. The present study is to develop hPer2 gene transfected HepG2 cell which can be used as hepatotoxicity test model for chemical. Materials and Methods: Plasmid DNA: gene was incorporated in pGL[Luc2P/Neo] (promega) vector to prepare pGL[hPer2P/Luc2P/Neo] and amplified with competent E.coli cell. Transfected celllines: HepG2(a human hepato cellular carcinoma... -
Establishment of hPer2 transfected HepG2 cell as hepatic circadian model
Hyuk Mi Lee, Young Il Park, Mingzhu Fang, Hwan Goo Kang, Jae Young Song 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 310 503-504 (2 pages)
or detoxify exogenous chemicals. The present study is to develop hPer2 gene transfected HepG2 cell which can be used as hepatotoxicity test model for chemical. Materials and Methods: Plasmid DNA: gene was incorporated in pGL[Luc2P/Neo] (promega) vector to prepare pGL[hPer2P/Luc2P/Neo] and amplified with competent E.coli cell. Transfected celllines: HepG2(a human hepato cellular carcinoma... -
Chondrogenic and Anti-Apoptotic Potential of Hypoxia in Canine Adipose Msenchymal Stem Cells
Jienny Lee, Keum Sil Lee, Ah Young Lee, Jeong Su Byeon, Sang Ho Cha 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 춘계학술심포지움 109 194-195 (2 pages)
Model So-Ye Jeon, Kyung-Chul Choi * Laboratory of Biochemistry and Immunology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Korea Introduction: Endogenous and exogenous steroid hormones may play important roles in ovarian carcinogenesis. Progesterone (P4) offers protection against ovarian carcinogenesis. We predicted that P4 would inhibit the migration of...