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전체 선택해제
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본문검색 결과만 보기
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Pak1/LIMK1/Cofilin Pathway Contributes to Tumor Migration and Invasion in Human Non-Small Cell Lung Carcinomas and Cell Lines
InseokJang, ByeongTakJeon, EunAeJeong, Eun-JinKim, DawonKang, JongSilLee, BaekGeunJeong, JinHyunKim6, BongHoiChoi6, JungEunLee, JongWooKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.3 2 159-165 (7 pages)
AC. Key Words: Pak1, LIMK1, Cofilin, Lung cancer INTRODUCTION Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related mortality worldwide. Early stage NSCLC can be cured surgically, but de spite the potential benefits of surgical resection, patients with the same pathologic stage of disease display marked variability in recurrence and sur- vival [1]. Squamous cell carcinoma... Squamous cell carcinoma (SCC) and adenocarcinoma (AC) are the major histological types of non-small cell lung carcinoma (NSCLC). Although both SCCs and ACs have been characterized histologically and clinically, the precise mechanisms underlying their migration and invasion are not yet known. Here, we address the involvement in NSCLC of the p21-associated kinase1 (Pak1)/LIM kinase1 (LIMK1)/cofilin pathway, which recently has been reported to play a critical role in tumor migration and invasion.... -
Effect of 5-FU and MTX on the Expression of Drug-resistance Related Cancer Stem Cell Markers in Non-small Cell Lung Cancer Cells
HeeYi, Hee-JungCho, Soo-MinCho, KyulJo, Jin-APark, Soo-HanLee, Byung-JoonChang, Jin-SukKim, Ho-ChulShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.1 2 11-16 (6 pages)
or MTX treatment, while the ..PAGE:3 Chemotherapeutics Increase Drug-resistance Related CSC Markers 13 Fig. 1. Analysis of ABCG2 expres- sion after 5-FU or MTX treatment. A549, H460, and H23 non-small cell lung cancer cell lines were treated with 5-FU (25 μg/ml) or MTX (50 μg/ ml) for 24 hours and incubated with a PE-anti-ABCG2 antibody. The num- ber of fluorescent-conjugated cells in 10... of drug-resistance related stem-cell surface markers, such as CD133 and ABCG2. Recently, we reported that CSCs have a high level of expression of the IL-6 receptor (IL-6R). The purpose of this study was to investigate the effect of anticancer drugs on the expression of the drug resistance-related cancer stem cell markers, ABCG2, IL-6R, and CD133 in non-small cell lung cancer (NSCLC) cell lines. A549, H460, and H23 NSCLC cell lines were treated with the anticancer drugs 5-fluorouracil (5-FU; 25... -
Hypermethylation of Growth Arrest DNA-Damage-Inducible Gene 45 in Non-Small Cell Lung Cancer and Its Relationship with Clinicopathologic Features
Na. Yeon-Kyung, Lee. Su-Man, Hong. Hae-Sook, Kim. Jae-Bum, Park. Jae-Yong, Kim. Dong-Sun 한국분자세포생물학회 Molecules and cells 4 Pages
한국분자세포생물학회 Molecules and cells 2010, Vol.30 No.1 89-92 (4 pages)
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Alternative drug therapies are superior to epidermal growth factor receptor -targeted chemotherapeutic drug responses in non-small cell lung cancer
Sikdar. Sourav, Khuda-Bukhsh. Anisur Rahman 탕정한의학회 TANG : International journal of genuine traditional medicine 2 Pages
탕정한의학회 TANG : International journal of genuine traditional medicine 2013, Vol.3 No.2 10-11 (2 pages)
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High Expression of Bcl-2 Protein Predicts Favorable Outcome in Non-small Cell Lung Cancer: Evidence from a Systematic Review and Meta-analysis
Zhao. Xian-Da, He. Yu-Yu, Gao. Jun, Zhao. Chen, Zhang. Ling-Lin, Tian. Jing-Yuan, Chen. Hong-Lei 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 9 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2014, Vol.15 No.20 8861-8869 (9 pages)
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Outcome of Daily Cisplatin with Thoracic Chemoradiotherapy in Advanced Non-small Cell Lung Cancer Patients with Comorbid Disorders: a Pilot Study
Kiziltan. Huriye Senay, Bayir. Ayse Gunes, Tastekin. Didem, Coban. Ganime, Eris. Ali Hikmet, Aydin. Teoman, Mayadagli. Alparslan 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 4 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2014, Vol.15 No.20 8591-8594 (4 pages)
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TGF-β1 Protein Expression in Non-Small Cell Lung Cancers is Correlated with Prognosis
Huang. Ai-Li, Liu. Shu-Guang, Qi. Wen-Juan, Zhao. Yun-Fei, Li. Yu-Mei, Lei. Bin, Sheng. Wen-Jie, Shen. Hong 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 5 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2014, Vol.15 No.19 8143-8147 (5 pages)
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Induction of Indoleamine 2,3-dioxygenase (IDO) Enzymatic Activity Contributes to Interferon-Gamma Induced Apoptosis and Death Receptor 5 Expression in Human Non-small Cell Lung Cancer Cells
Chung. Ting Wen, Tan. Kok-Tong, Chan. Hong-Lin, Lai. Ming-Derg, Yen. Meng-Chi, Li. Yi-Ron, Lin. Sheng Hao, Lin. Chi-Chen 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 7 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2014, Vol.15 No.18 7995-8001 (7 pages)
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Bevacizumab Concomitant with Chemotherapy is Effective in Treating Chinese Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer
Sun. Jing, Hu. Yi, Wu. Bai-Shou, Wang. Jin-Liang, Tao. Hai-Tao, Zhang. Su-Jie 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 6 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2014, Vol.15 No.14 5945-5950 (6 pages)