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The effect of physical training on glutamate transporter expression in an experimental ischemic stroke rat model
Gye-Yeop Kim, Eun-Jung Kim 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2013, 제 2권 제 2호 5 87-91 (5 pages)
* p＜0.05 compared to Group I, ** p＜0.05 compared to Group II. Data analysis Data analysis was performed with PASW Statistics 18.0 (IBM Co., Armonk, NY, USA). All of the data were ex- pressed as mean±standard deviation (SD). Differences in limb placement test scores were examined with a parametric one-way ANOVA and Scheffe’s post hoc procedure at 95% significance levels. For test based on... Objective: The present study was aimed at determining the effect of physical training on glutamate transporter activity in a middle cerebral artery occlusion (MCAO)-induced ischemia injury rat model. Design: Randomized controlled trial. Methods: In this study, we randomly divided them into three groups. Group I included non-occlusion sham controls (n=10), Group II included non-physical training after MCAO (n=10), and Group III included rats that were subjected to physical training after MCAO... -
Extent of Mycobacterium bovis infection in dairy cattle herds subject to partial culling as determined by an interferon-gamma assay
Sungmo Je, Un-chang Yeo, Taeksun Song, Ki-cheol Kim, Sung-Yun Park, Man-Jung Kim, Sang-Nae Cho* 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 2호 12 259-265 (7 pages)
to compare nonparametric unpaired data. A p value < 0.05 was considered to be significant. Results IFN-γ responses in SIDT-positive and SIDT- negative cattle A whole blood assay was established in a 96-well culture plate format to determine IFN-γ production after stimulation with the recombinant ESAT-6 and CFP-10 antigen cocktail. The IFN-γ concentration in each well was determined by... The interferon-gamma (IFN-γ) assay is employed as a complementary diagnostic test for bovine tuberculosis (BTB) in many countries. To simplify this assay, we established a 96-well plate format using the ESAT-6 and CFP-10 antigens and then employed it to determine the extent of Mycobacterium (M.) bovis infection in dairy herds with a history of BTB outbreaks in a country where only selective culling is practiced. The sensitivity and specificity of this IFN-γ assay were 85.9% and 100%,... -
공간분석방법의 고고학적 활용과 문제점
權學洙(Haksoo Kwon) 한국고고학회 한국고고학보 25 Pages
한국고고학회 한국고고학보 1999, 제 40집 1 1-25 (25 pages)
test,leads to the loss of spatial information and the accuracy of interpretation. Therefore such techniques as correlation analysis, contour mapping, and trend surface analysis, all of which deal with numerical data measured at least in interval scale, were recommended as a basic tool to examine spatial data and to find underlying structures. Secondly, quadrat method involving x 2 test,one of the... -
Modeling of the Parathyroid Hormone Response after Calcium Intake in Healthy Subjects
JaeEunAhn, SangilJeon, JongtaeLee, SeunghoonHan, Dong-SeokYim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.3 4 217-223 (7 pages)
were compared with those ob- served in this study. For bootstrap, 500 data sets were sam- pled with replacement and nonparametric 95% confidence intervals (2.5∼97.5 percentiles), and the median values were assessed using the runs with successful minimization. Software/ platform The analysis was performed using NONMEM 7.2.0 (ICON Development Solutions, MD) in the Pirana 2.6.1 platform [5]. R... Plasma ionized calcium (Ca2+) concentrations are tightly regulated in the body and maintained within a narrow range; thus it is challenging to quantify calcium absorption under normal physiologic conditions. This study aimed to develop a mechanistic model for the parathyroid hormone (PTH) response after calcium intake and indirectly compare the difference in oral calcium absorption from PTH responses. PTH and Ca2+ concentrations were collected from 24 subjects from a clinical trial performed to... -
Changes in c-Fos Expression in the Forced Swimming Test: Common and Distinct Modulation in Rat Brain by Desipramine and Citalopram
SunHyeChoi, SungChung, JinHeeCho, YunHaCho, JinWookKim, JeongMinKim, HeeJeongKim, HyunJuKim, KyungHoShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.4 10 321-329 (9 pages)
by nonparametric Kruskal-Wallis test and post hoc Mann-Whitney U test; significant p-values denote comparisons surviving Bonferroni correction (*p ＜0.05/6= 0.00833; ***p＜0.001/6=0.00016). The quantitative data are reported as means±the standard errors of the means (S.E.M.). RESULTS Effects of antidepressants on the pretest swim-induced changes in c-Fos expression in the ventral lateral... Rodents exposed to a 15-min pretest swim in the forced swimming test (FST) exhibit prolonged immobility in a subsequent 5-min test swim, and antidepressant treatment before the test swim reduces immobility. At present, neuronal circuits recruited by antidepressant before the test swim remain unclear, and also less is known about whether antidepressants with different mechanisms of action could influence neural circuits differentially. To reveal the neural circuits associated with antidepressant... -
Standard Error of Empirical Bayes Estimate in NONMEMⰒ VI
DongwooKang, Kyun-SeopBae, BrettE.Houk, RadojkaM.Savic, MatsO.Karlsson 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.2 3 97-106 (10 pages)
observations/subject) EBE can be used to test the normal distribution assumption on Ω, or the validity of the mixture model, or the necessity of using some other kind of nonparametric distribution. Since EBEs are used in the ob jective function calculation in FOCE or Laplacian method, both methods rely on accu- rate EBEs. In NONMEM VI, EBE can be used as support points to calculate the join... The pharmacokinetics/pharmacodynamics analysis software NONMEMⰒ output provides model parameter estimates and associated standard errors. However, the standard error of empirical Bayes estimates of inter-subject variability is not available. A simple and direct method for estimating standard error of the empirical Bayes estimates of inter-subject variability using the NONMEMⰒ VI internal matrix POSTV is developed and applied to several pharmacokinetic models using intensively or... -
의학통계학적 방법의 사용과 오류
김동기, 한무영, 한혜리 대한신경정신의학회 신경정신의학 7 Pages
대한신경정신의학회 신경정신의학 2004, 제 43권 제 2호 2 141-147 (7 pages)
(Nonparametric analysis ) Spearman correlation Pearson correlation 의 비모수적 방법 χ2-test r× c 형태의 표에서 독립성이나 동질성을 알아보기 위한 방법 Fisher’s exact test Cell에 0이 포함되어있거나, 한 cell의 수가 5 미만일 경우에 χ2-test 대신 사용 Trend test 순위형 자료의 추세를 보기 위해 사용하는 방법 McNemar test 이분형 자료를 반복해서 관찰하였을 때, 전후의 차이가 있는지 검정할 때... -
한국인 정신분열병 환자에서 COMT 유전자내의 단일염기 다형성 분석
이동기, 김성환, 최병무, 박재홍, 손성락, 강호진, 홍영습 대한신경정신의학회 신경정신의학 9 Pages
대한신경정신의학회 신경정신의학 2010, 제 49권 제 2호 11 201-209 (9 pages)
서 정보를 반영한 Cochran-Armitage 추세 검정(Cochran- Armitages trend test)을 실시하였고, 비모수적 분석 방법 (nonparametric method)으로 Fisher 정확 검정(Fishers exact test)과 Jonckheere-Terpstra 검정을 실시하였다. 그리고 성별과 연령을 고려한 수정 오즈비(adjust Odds Ra- tio)를 산출하였고, 통계적 분석은 SAS software를 이용하 였다(version 9.1, Cary, NC, USA). Table 2. The frequency of allele for the... -
神經精神醫學에 發表된 論文들의 統計方法의 技術 및 適用 現況
曹沫哲, 安允玉 대한신경정신의학회 신경정신의학 15 Pages
대한신경정신의학회 신경정신의학 1991, 제 30권 제 3호 3 462-476 (15 pages)
69.7 % (101/145) for the chi-squared test, 71.6% (48/ 67) for the analysis of variance, 32.4% (23/71) for the Pearson correlation, 18.2% (2/11) for the nonparametric correlation, 15.0% (3/20) for the nonparametric method, and 70.0% (14 /20) for the factor analysis contained statistcial problems. It was suggested that a basic training in statistical methods, more intensive consultation of... -
지적장애학생을 위한 긍정적 행동지원(PBS) 적용 효과 : 단일대상연구 메타분석
김병건, 박유정, 고혜정 한국행동분석학회 행동분석·지원연구 18 Pages
한국행동분석학회 행동분석·지원연구 2020, 제 7권 제 2호 2 19-36 (18 pages)
& Rothstein, H. R. (2009). Introduction to meta-analysis. Chichester, UK: Wiley. Duval, S., & Tweedie, R. (2000). A nonparametric “trim and fill” method of accounting for publication bias in meta-analysis. Journal of the American Statistical Association, 95 (499), 89-98. Gast, D. L., & Ledford, J. R. (2014). Single case research methodology: Applications in special education and behavioral... 본 연구에서는 지적장애학생들에게 적용되어 온 긍정적 행동지원(Positive Behavior Supports: PBS) 기반 중재의 적용 효과를 살펴보고 이를 바탕으로 효과적인 교실 적용 가능성에 대해 탐색하고자 단일대상연구들을 대상으로 메타분석 접근을 적용하였다. 이를 위해 무선효과모형을 활용하여 총 25편의 단일대상연구들의 Tau-U 효과크기를 분석하였고, 효과크기에 영향을 미치는 변인들(학교레벨, 중재유형, 회기, 장애정도, 성별)을 파악하여 PBS 기반 중재의 효과성과 특성에 대해 살펴보았다. 그 결과, 지적장애학생들을 위한 PBS...