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Association of SNAP-25 Gene Ddel and Mnll Polymorphisms with Adult Attention Deficit Hyperactivity Disorder
Hasan Herken, Mehmet Emin Erdal, Ayse Nur Inci Kenar, Gonca Ayse Unal, Burcu Ç, akaloz, Mustafa Ertan Ay, Erinç, Yucel, Tuba Ed 대한신경정신의학회 Psychiatry Investigation 5 Pages
대한신경정신의학회 Psychiatry Investigation 2014, 제 11권 제 4호 16 476-480 (5 pages)
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한국형 단축형 부모용 Swanson, Nolan and Pelham 제4판 (SNAP-IV) 척도의 신뢰도 및 타당도 연구
서완석, 장혜경, 김진성, 이종범 대한신경정신의학회 신경정신의학 9 Pages
대한신경정신의학회 신경정신의학 2008, 제 47권 제 1호 9 64-72 (9 pages)
..PAGE:1 online ML Comm J Korean Neuropsychiatr Assoc / Volume 47, No 1 / January, 2008 64 J Korean Neuropsychiatr Assoc Vol 47, No 1 ORIGINAL ARTICLE 한국형 단축형 부모용 Swanson, Nolan and Pelham 제4판 (SNAP-IV) 척도의 신뢰도 및 타당도 연구 영남대학교 의과대학 정신과학교실 서완석·장혜경·김진성·이종범 Reliability and Validity of Short Form, Parental Version of the Korean Swanson, Nolan... -
흑미 가루의 첨가가 sugar-snap cookie의 품질 특성에 미치는 영향
박영서, 장학길, Park. Young-Seo, Chang. Hak-Gil 한국식품과학회 한국식품과학회지 4 Pages
한국식품과학회 한국식품과학회지 2008, Vol.40 No.2 234-237 (4 pages)
밀가루에 흑미가루를 첨가하여 제조한 sugar-snap 쿠키의 품질특성을 조사하였다. Sugar-snap 쿠키의 반죽의 pH는 흑미 가루의 첨가량이 증가함에 따라 감소하였다. 쿠키의 직경과 퍼짐성은 흑미 가루의 첨가량이 증가함에 따라 증가하였고 두께와 파괴강도는 감소하였다. L, a, 및 b값 역시 흑미 가루 첨가량이 증가함에 따라서 다소 감소하는 경향을 나타내었다. Sugar-snap 쿠키의 종합적 기호도는 강력분의 경우는 흑미가루 20% 첨가 시, 중력분은 25% 첨가 시, 박력분은 20% 첨가 시에 가장 좋은 것으로 평가되었다. -
Glucose/Oxygen Deprivation Induces Release of [3H]5-hydroxytryptamine Associated with Synapsin 1 Expression in Rat Hippocampal Slices
EunMiPark, SangHuiChu, KyungEunLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.5 2 347-353 (7 pages)
syntaxin and SNAP-25 were not altered during GOD. These results suggest that ischemic insult induces release of eH]5-HT associated with synapsin 1， synaptic vesicular protein， via activation of NMDA receptor in part. Key Words: Hippocampal slices， Glucosejoxygen deprivation， 5-Hydroxytryptamine， Synapsin， Syntaxin， SNAP-25 INTRODUCTION Brain tissues have high energy demand requiring a... the ischemic neuronal injury. But there is no information regarding whether the release of monoamines is directly associated with synaptic vesicular proteins under ischemia. In the present study, it was investigated whether synapsin 1, syntaxin and SNAP-25 are involved in the release of 5-hydroxytryptamine ([3H]5-HT) in glucose/oxygen deprived (GOD) rat hippocampal slices. And, the effect of NMDA receptor using DL-2-amino-5-phosphonovaleric acid (APV) on ischemia- induced release of 5-HT and the... -
Escitalopram, a selective serotonin reuptake inhibitor, inhibits voltage-dependent K+ channels in coronary arterial smooth muscle cells
HanSolKim, HongliangLi, HyeWonKim, SungEunShin, MiSeonSeo, JinRyeolAn, Kwon-SooHa, Eun-TaekHan, Seok-HoHong, Il-WhanChoi, GraceChoi, Dae-su 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.4 7 415-421 (7 pages)
SNAP-25(1-180) enhances insulin secretion by blocking Kv2.1 channels in rat pancreatic islet beta-cells. Biochem Biophys Res Commun. 2009;379:812-816. 15. Snyders DJ, Yeola SW. Determinants of antiarrhythmic drug action. Electrostatic and hydrophobic components of block of the human cardiac hKv1.5 channel. Circ Res. 1995;77:575-583. 16. Lee HA, Hyun SA, Park SG, Kim KS, Kim SJ. Comparison of... We investigated the inhibitory effect of escitalopram, a selective serotonin reuptake inhibitor (SSRI), on voltage-dependent K+ (Kv) channels in freshly separated from rabbit coronary arterial smooth muscle cells. The application of escitalopram rapidly inhibited vascular Kv channels. Kv currents were progressively inhibited by an increase in the concentrations of escitalopram, suggesting that escitalopram inhibited vascular Kv currents in a concentration-dependent manner. The IC50 value and... -
Phorbol 12-Myristate 13-Acetate Enhances Long-Term Potentiation in the Hippocampus through Activation of Protein Kinase CՄ and Յ
EungChangKim, MyeongJongLee, SangYepShin, GeunHeeSeol, SeungHoHan, JaeyongYee, ChanKim, SunSeekMin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.1 8 51-56 (6 pages)
significance. Prog Neuropsy- chopharmacol Biol Psychiatry. 1997;21:531-572. 21. Lau CG, Takayasu Y, Rodenas-Ruano A, Paternain AV, Lerma J, Bennett MV, Zukin RS. SNAP-25 is a target of protein kinase C phosphorylation critical to NMDA receptor trafficking. J Neurosci. 2010;30:242-254. 22. Lan JY, Skeberdis VA, Jover T, Grooms SY, Lin Y, Araneda RC, Zheng X, Bennett MV, Zukin RS. Protein kinase... Many intracellular proteins and signaling cascades contribute to the sensitivity of N-methyl-D- aspartate receptors (NMDARs). One such putative contributor is the serine/threonine kinase, protein kinase C (PKC). Activation of PKC by phorbol 12-myristate 13-acetate (PMA) causes activation of extracellular signal-regulated kinase (ERK) and promotes the formation of new spines in cultured hippocampal neurons. The purpose of this study was to examine which PKC isoforms are responsible for the... -
Prolonged expression of senescence markers in mice exposed to gamma-irradiation
Min-A Seol, Uhee Jung*, Hyeon Soo Eom, Seol-Hwa Kim, Hae-Ran Park, Sung-Kee Jo 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2012, 제 13권 제 4호 1 331-338 (8 pages)
..PAGE:1 J O U R N A L O F Veterinary Science pISSN 1229-845X, eISSN 1976-555X J. Vet. Sci. (2012), 13(4), 331-338 http://dx.doi.org/10.4142/jvs.2012.13.4.331 Received: 29 Jul. 2011, Revised: 3 May 2012, Accepted: 4 Jun. 2012 Original Article *Corresponding author: Tel: +82-63-570-3221; Fax: +82-63-570-3229; E-mail: uhjung@kaeri.re.kr † The first two authors contributed equally to this work. ⓒ... Although ionizing radiation is known to induce cellular senescence in vitro and in vivo, its long-term in vivo effects are not well defined. In this study, we examined the prolonged expression of senescence markers in mice irradiated with single or fractionated doses. C57BL/6 female mice were exposed to 5 Gy of γ-rays in single or 5, 10, 25 fractions. At 2, 4, and 6 months after irradiation, senescence markers including mitochondrial DNA (mtDNA) common deletion, p21, and senescence-associated... -
Catheter-guided percutaneous heartworm removal using a nitinol basket in dogs with caval syndrome
Won-Kyoung Yoon, Donghyun Han, Changbaig Hyun 대한수의학회 Journal of Veterinary Science 3 Pages
대한수의학회 Journal of Veterinary Science 2011, 제 12권 제 2호 15 199-201 (3 pages)
..PAGE:1 J O U R N A L O F Veterinary Science pISSN 1229-845X, eISSN 1976-555X J. Vet. Sci. (2011), 12(2), 199-201 DOI: 10.4142/jvs.2011.12.2.199 Received: 07 Sep. 2010, Accepted: 18 Oct. 2010 Case Report *Corresponding author Tel: +82-33-250-8681; Fax: +82-33-244-2367 E-mail: hyun5188@kangwon.ac.kr Catheter-guided percutaneous heartworm removal using a nitinol basket in dogs with caval syndrome... Carval syndrome is a severe heartworm infection where the worms have migrated to the right atrium and vena cava; this condition is associated with a myriad of clinical signs. Several non-surgical and interventional methods are currently used for mechanical worm removal. However, the success rate and complications related to these methods are heavily dependent on methodology and retrieval devices used. In this study, we developed a catheter-guided heartworm removal method using a retrieval basket... -
Effects of intermittent ladder-climbing exercise training on mitochondrial biogenesis and endoplasmic reticulum stress of the cardiac muscle in obese middle-aged rats
KijinKim, NayoungAhn, SuryunJung, SoleePark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.6 8 633-641 (9 pages)
..PAGE:1 www.kjpp.net Korean J Physiol Pharmacol 2017;21(6):633-641 633 Korean J Physiol Pharmacol 2017;21(6):633-641 https://doi.org/10.4196/kjpp.2017.21.6.633 Author contributions: S.P. performed animal experiment and western blotting analysis. S.J. interpreted data and wrote the manuscript. N.A. and K.K. designed study and revised article. This is an Open Access article distributed under the... The aim of this study is to investigate the effects of intermittent ladder-climbing exercise training on mitochondrial biogenesis and ER stress of the cardiac muscle in high fat diet-induced obese middle-aged rats. We induced obesity over 6 weeks of period in 40 male Sprague-Dawley rats around 50 weeks old, and were randomly divided into four experimental groups: chow, HFD, exercise+HFD, and exercise+chow. The exercising groups underwent high-intensity intermittent training using a... -
Effects of Acupuncture Stimulation at Different Acupoints on Formalin-Induced Pain in Rats
KyungHaChang, SunJoonBai, HyejungLee, BaeHwanLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.2 5 121-127 (7 pages)
..PAGE:1 121 Korean J Physiol Pharmacol Vol 18: 121 －127, April, 2014 http://dx.doi.org/10.4196/kjpp.2014.18.2.121 ABBREVIATIONS: BL60, Kunlun; SP9, Yinlingquan; ST36, Zusanli; CFA, complete Freund's adjuvant; For, formalin; NA, non-acupoint; NGS, normal goat serum; BSA, bovine serum albumin; DAB, 3,3’-diaminobenzidine; NMDA, N-methyl-D-aspartate. Received November 8, 2013, Revised February... Acupuncture is the process of stimulating skin regions called meridians or acupoints and has been used to treat pain-related symptoms. However, the pain-relieving effects of acupuncture may be different depending on acupoints. In the present study, the effects of acupuncture on behavioral responses and c-Fos expression were evaluated using a formalin test in male Sprague-Dawley rats in order to clarify the analgesic effects of three different acupoints. Each rat received manual acupuncture at...