자료유형
발행기관
- 대한수의학회(322)
- 대한생리학회-대한약리학회(315)
- 한국식물병리학회(108)
- 대한약리학회(15)
- 대한신경정신의학회(12)
- 대한생리학회(10)
- 한방비만학회(9)
- 대한치과교정학회(8)
- 물리치료재활과학회(6)
- 대한구순구개열학회(4)
- 한국기초간호학회(4)
- 대한방사선종양학회(3)
- 대한치과이식임플란트학회(3)
- 대한방사선치료학회(2)
- 한국교원대학교 뇌기반교육연구소(2)
- 한국습지학회(2)
- 한국청각언어재활학회(2)
- 한국초등체육학회(2)
- 한국탄소학회(2)
- 고려인삼학회(1)
- 대한방사선과학회(1)
- 대한신경계작업치료학회(1)
- 대한의용생체공학회(1)
- 한국공업화학회(1)
- 한국교육학회(1)
- 한국웰니스학회(1)
- 한국의학물리학회(1)
- 한국헬스커뮤니케이션학회(1)
- 한국환경농학회(1)
- 환태평양유아교육연구학회(1)
간행물
- THE KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY(315)
- JOURNAL OF VETERINARY SCIENCE(201)
- THE PLANT PATHOLOGY JOURNAL (97)
- 대한수의학회 학술대회발표집(80)
- KOREAN JOURNAL OF VETERINARY RESEARCH(구 대한수의학회지)(41)
- 대한약리학잡지(15)
- 식물병연구(11)
- 신경정신의학(11)
- 대한생리학회지(10)
- 대한한방비만학회지(9)
- THE KOREAN JOURNAL OF ORTHODONTICS(8)
- PHYSICAL THERAPY REHABILITATION SCIENCE(6)
- JOURNAL OF KOREAN BIOLOGICAL NURSING SCIENCE(4)
- 대한구순구개열학회지(4)
- JOURNAL OF DENTAL IMPLANT RESEARCH(3)
- 대한방사선종양학회지(3)
- AUDIOLOGY AND SPEECH RESEARCH(2)
- CARBON LETTERS(2)
- 대한방사선치료학회지(2)
- 한국습지학회지(2)
- 한국초등체육학회지(2)
- ASIA-PACIFIC JOURNAL OF RESEARCH IN EARLY CHILDHOOD EDUCATION(1)
- BRAIN & LEARNING(1)
- BRAIN, DIGITAL, & LEARNING(1)
- JOURNAL OF BIOMEDICAL ENGINEERING RESEARCH : THE OFFICIAL JOURNAL OF THE KOREAN SOCIETY OF MEDICAL &(1)
- PSYCHIATRY INVESTIGATION(1)
- 고려인삼학회지(1)
- 공업화학(1)
- 대한방사선기술학회지(1)
- 의학물리(1)
- 재활치료과학(1)
- 한국교육학회 학술대회논문집(1)
- 한국웰니스학회지(1)
- 한국환경농학회지(1)
- 헬스커뮤니케이션연구(1)
전체 선택해제
총 842건 검색
본문검색 결과만 보기
-
Enhanced Hepatogenic Transdifferentiation of Human Adipose Tissue Mesenchymal Stem Cells by Gene Engineering with Oct4 and Sox2
Sei Myoung Han, Goo Jang, Kee Ok Jeon, Sang Chul Park, Woojin Song, Min Ok Ryu, Quiang Li, Aryung Nam, Ji Ye Lee, Sung Keun Kang, Hee Woo 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 춘계학술심포지움 168 226-226 (1 pages)
program. The validation of the transgene position, which was found by computer predicted sequence, transposition site with transgene were amplified by target specific PCR primers and sequenced. In this manual analysis, sleeping beauty-mediated integration was found to occur TA duplication of the insertion site. Conclusions: In conclusion, for the first time we have generated successfully a... -
Human Umbilical Cord Blood Mesenchymal Stem Cell Delivered Intra-nasally : A Noninvasive Stem Cell Therapy to Target Niemann-Pick Type C1
In sung Kang, Yoo jin Seo, Hyung Sik Kim, Kyung Sun Kang 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 379 397-397 (1 pages)
small rodent model. J Tissue Eng Regen Med 2015. [3] Gilbert TW, Sellaro TL, Badylak SF. Decellularization of tissues and organs. Biomaterials 2016. 27, 3675-3683. P-319 Human Umbilical Cord Blood Mesenchymal Stem Cell Delivered Intra-nasally : A Noninvasive Stem Cell Therapy to Target Niemann-Pick Type C1 Insung Kang 1, Yoojin Seo 2,3, Hyung-Sik Kim 2,3, Kyung-Sun Kang *1 1Research Institute... -
Guanylyl cyclase C and guanylin reduce fat droplet accumulation in cattle mesenteric adipose tissue
Masahiro Yasuda, Jyunya Kawabata, Sayaka Akieda-Asai, Tetsuo Nasu, Yukari Date 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 3호 11 341-348 (8 pages)
BigDye Terminator v3.1 Cycle Sequencing Kit (Applied Biosystems, Japan). The resulting sequencing data indicated that each primer set amplified its target gene precisely (data not shown). Isolation and preservation of the SVF Approximately 2 g of mesenteric adipose tissue were collected, washed with Hank’s balanced salt solution (HBSS; Invitrogen, USA), minced with scissors, and incubated in... in rat mesenteric adipose tissue macrophages. To examine the role of GC-C and GNY in lipid metabolism in cattle, we used a bovine mesenteric adipocyte primary culture system and a coculture system for bovine adipocytes and GNY-/GC-C-expressing macrophages. Fat droplets were observed to accumulate in bovine mesenteric adipocytes cultured alone, whereas few fat droplets accumulated in adipocytes indirectly cocultured with macrophages. We also observed that GC-C was present in bovine mesenteric... -
Duplex nested reverse transcriptase polymerase chain reaction for simultaneous detection of type 2 porcine reproductive and respiratory syndrome virus and porcine circovirus type 2 from tissue samples
Hye Kwon Kim, Kwang Soo Lyoo, Thi My Le Huynh, Hyoung Joon Moon, Van Giap Nguyen, Bong Kyun Park 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 2호 16 253-256 (4 pages)
CP07-401-9). As shown in Fig. 1, the duplex nested RT-PCR successfully amplified target bands of 265 bp for PCV2 (lane 5) and 347 bp for type 2 PRRSV (lane 6). Non-specific amplification was not visualized when the templates were prepared from either PCV1-infected PK15 cells (lanes 13), PCV1-free PK15 cells (lane 4), or MARC-145 cells (lane 8). Two specific PCR products were observed from a... 2 (PCV2) in porcine tissue. This study established a duplex nested reverse transcriptase polymerase chain reaction (RT-PCR) method that targets the genomic RNA of type 2 PRRSV and the mRNA of PCV2 in infected tissues. The method amplified discriminative bands of 347 bp and 265 bp specific for type 2 PRRSV and PCV2, respectively. The limits of detection of the duplex nested RT-PCR were 10 TCID50/mL for type 2 PRRSV and 10 infected cells/mL for PCV2. The kappa statistic, which measures agreement... -
Temporal changes in mammalian target of rapamycin (mTOR) and phosphorylated-mTOR expressions in the hippocampal CA1 region of rat with vascular dementia
Jin-A Park, Choong-Hyun Lee 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 1호 2 11-16 (6 pages)
mammalian target of rapamycin (mTOR) and phosphorylated-mTOR expressions in the hippocampal CA1 region of rat with vascular dementia Jin-A Park, Choong-Hyun Lee* Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan 31116, Korea Mammalian target of rapamycin (mTOR) has an important role in various biological processes in cells. In the present study, we investigated temporal... Mammalian target of rapamycin (mTOR) has an important role in various biological processes in cells. In the present study, we investigated temporal changes in mTOR and phosphorylated-mTOR (p-mTOR) expressions in the rat hippocampal CA1 region following chronic cerebral hypoperfusion (CCH) induced by permanent bilateral common carotid arteries occlusion (2VO). The mTOR immunoreactivity in the pyramidal neurons and mTOR protein level in the hippocampal CA1 region were markedly decreased at 21 and... -
Preparation and evaluation of enrofloxacin microspheres and tissue distribution in rats
Fan Yang, Jijun Kang, Fang Yang, Zhensheng Zhao, Tao Kong, Zhenling Zeng 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 2호 4 157-164 (8 pages)
of target animals (e.g., dogs and cats) would be sacrificed during tissue distribution experiments, rodents were chosen as the primary model species to evaluate the lung-targeting abilities of different preparations. The objectives of this study were to develop and characterize an ENR microsphere (ENR-MIC), ..PAGE:2 158 Fan Yang et al. Journal of Veterinary Science and determine whether this... New enrofloxacin microspheres were formulated, and their physical properties, lung-targeting ability, and tissue distribution in rats were examined. The microspheres had a regular and round shape. The mean diameter was 10.06 μm, and the diameter of 89.93% of all microspheres ranged from 7.0 μm to 30.0 μm. Tissue distribution of the microspheres was evaluated along with a conventional enrofloxacin preparation after a single intravenous injection (7.5 mg of enrofloxacin/kg bw). The results... -
The production and distribution of IL-6 and TNF-α in subcutaneous adipose tissue and their correlation with serum concentrations in Welsh ponies with equine metabolic syndrome
Katarzyna Basinska, Krzysztof Marycz, Agnieszka ?mieszek, Jakub Nicpo? 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 1호 15 113-120 (8 pages)
labeling was performed using polyclonal antibodies against IL-6 (Genorise Scientific) and TNF- (R&D Systems, USA). Antigen heat-induced retrieval was performed by incubating the slides with target retrieval solution (pH 9.0; Dako) for 20 min at 96 oC. Endogenous peroxidase activity was blocked with 3% hydrogen peroxide and the slides were then washed with Tris-buffered saline (TBS) for 5 min... was performed. The results obtained showed that IL-6 expression in adipose tissue biopsies derived from animals with EMS was enhanced while TNF-α levels of both groups were comparable. Compared to the obese ponies, EMS animals also had significantly elevated levels of serum IL-6 and TNF-α. Histological analysis revealed macrophage infiltration and fibrosis in adipose tissue preparations from the EMS group. These data suggest that IL-6 may play a key... -
Tissue-specific expression of the NOD-like receptor protein 3 in BALB/c mice
Zhiqiang Huang, Meng Yu, Shuang Tong, Kun Jia, Rongchang Liu, Heng Wang, Shoujun Li*, Zhangyong Ning* 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 2호 1 173-177 (5 pages)
of these two target gene fragments showed 100% homology with the original sequences. NLRP3 mRNA was expressed in all BALB/c mice tissues examined (Fig. 1). The expression of NLRP3 in kidney and lymph nodes was higher than that in other tissues. Immunohistochemical analysis of NLRP3 distribution in BALB/c mice tissues Immunohistochemical analysis revealed tissue-specific variation in NLRP3... roles in the inflammatory and innate immune responses associated with autoimmune/inflammatory syndrome. However, analysis of the tissue distribution and expression profiles in BALB/c mice is still incomplete. In this study, we investigated the tissue distribution and expression pattern of NLRP3 in BALB/c mice to further elucidate its function in innate immunity in this commonly used laboratory animal model. NLRP3 mRNA expression levels and tissue distribution of the protein were investigated by... -
Development of a multiplex PCR to identify Salmonella, Leptospira and Brucella species in tissue samples
Truong Quang Lam , Byung Il Yoon , Tae Wook Hahn 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 8 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2012, 제 52권 제 2호 3 75-82 (8 pages)
tissue samples did not reduce the ability of the PCR or mPCR to detect specific target genes or different combinations of the three infectious pathogens. This result suggests that other primer pairs might also be used for the direct detection of Brucella species in tissue samples. The positive PCR results for Salmonella were confirmed by isolation of the pathogen from the tissue (data not show),... -
Cyclophilin A as a New Therapeutic Target for Hepatitis C Virus- induced Hepatocellular Carcinoma
JinhwaLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.5 1 375-383 (9 pages)
Recent studies indicate that PPIases utilize isomer- ization catalysis on the substrate proteins under both phys- iological and pathophysiological conditions. Then, the de- velopment of isoenzyme-, tissue- or organelle-specific PPIase inhibitors will open a new road for cancer inter- vention strategies. CYPA AS A THERAPEUTIC TARGET FOR HCC Targeting CypA for cancer therapeutics has recently be-... good target for molecular cancer therapy. Because of antiviral activity, the CypA inhibitors have been tested for the treatment of chronic hepatitis C. Nonimmunosuppressive Cyp inhibitors such as NIM811, SCY-635, and Alisporivir have attracted more interests for appropriating CypA for antiviral chemotherapeutic target on HCV infection. This review describes CypA inhibitors as a potential HCC treatment tool that is contrived by their obstructing chronic HCV infection and summarizes roles of CypA...