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Anti-fatigueactivities of Korean Red Ginseng and Antler Velvet response to exhaustiveswimming exercise
Shang Jin Kim 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 195 316-317 (2 pages)
adenosine triphosphate (ATP), hexokinase (HE), citrate synthase (CS), malondialdehyde (MDA) and superoxidedismutase (SOD) in quadriceps muscle were measured by spectrophotometry. Also,the Transient receptor potential melastatin-7 (TRPM7) channels and solutecarrier family 41 member A1 (SLC41A1) gene expressions were measured byreal-time PCR. Results: After exercise, Mg in serum, heart,... -
Transient forebrain ischemia induces impairment in cognitive performance prior to extensive neuronal cell death in Mongolian gerbil (Meriones unguiculatus)
Tomohiro Kondo, Suguru Yoshida, Hiroaki Nagai, Ai Takeshita, Masaki Mino, Hiroshi Morioka, Takayuki Nakajima, Ken Takeshi Kusakabe, Tosh 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 4호 5 505-511 (7 pages)
the transient forebrain ischemia, suggesting that the defects in associative/contextual memory are related to the hippocampal neuronal cell death. This notion is supported by the report by Soeda et al. [32] that showed that the step-through passive avoidance response requires hippocampus-dependent learning. In the Sham group, latency time decreased with each trial over the 1st to 3rd and 4th... In Mongolian gerbils, bilateral common carotid artery occlusion (BCCAO) for several minutes induces ischemia, due to an incomplete circle of Willis, resulting in delayed neuronal cell death in the Cornet d’Ammon 1 (CA1) region of the hippocampus. Neuronal cell death in the hippocampus and changes in behavior were examined after BCCAO was performed for 5 min in the gerbils. One day after BCCAO, the pyramidal neurons of the CA1 region of the hippocampus showed degenerative changes (clumped... -
The Characteristics of Supramammillary Cells Projecting to the Hippocampus in Stress Response in the Rat
WoongKiChoi, DavidWirtshafter, Hyun-JungPark, , Mi-SookLee, , SongHer, InsopShim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.1 3 17-24 (8 pages)
in response to stress. IMO stress is acknowledged to be involved in psy- chological and physical stress by altering behavioral and physiological responses [27,28]. IMO stress acutely initiates a transient increase in CRF ex pression in the PVN and pro- duces increased plasma corticosterone in the present study (data not shown). The majority of CRF-immunoreactive cells have been found to... The hypothalamus-pituitary-adrenocortex (HPA) axis is the central mediator of the stress response. The supramammillary (SuM) region is relatively unique among the hypothalamic structures in that it sends a large, direct projection to the hippocampal formation. It has been shown that mild stress could activate the SuM cells that project to the hippocampus. However, the role of these cell populations in modulating the stress response is not known. The present study examined the effect of stress on... -
CD40 Co-stimulation Inhibits Sustained BCR-induced Ca2＋ Signaling in Response to Long-term Antigenic Stimulation of Immature B Cells
YenHoangNguyen, Ki-YoungLee, TaeJinKim, SungJoonKim, TongMookKang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.3 9 179-187 (9 pages)
110-799, Korea Regulation of B cell receptor (BCR)-induced Ca 2＋ signaling by CD40 co-stimulation was compared in long-term BCR-stimulated immature (WEHI-231) and mature (Bal-17) B cells. In response to long-term pre-stimulation of immature WEHI-231 cells to α-IgM antibody (0.5 ∼48 hr), the initial transient decrease in BCR-induced [Ca 2＋]i was followed by spontaneous recovery to control... In response to long-term pre-stimulation of immature WEHI-231 cells to Ձ-IgM antibody (0.5∼48 hr), the initial transient decrease in BCR-induced [Ca2＋]i was followed by spontaneous recovery to control level within 24 hr. The recovery of Ca2＋ signaling in WEHI-231 cells was not due to restoration of internalized receptor but instead to an increase in the levels of PLCՃ2 and IP3R-3. CD40 co-stimulation of WEHI-231 cells prevented BCR-induced cell cycle arrest and apoptosis, and it... -
Involvement of Endoplasmic Reticulum Stress Response in the Neuronal Differentiation
YoonMiCho, YoonSeongJang, Young-MinJang, Jin-YoungSeo, HoShikKim, JeongHwaLee, SeongWhanJeong, InKyungKim, Oh-JooKwon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.6 2 239-248 (10 pages)
of ER stress response was examined. Expressions of phosphorylated forms of PERK (P-PERK) and eIF2α (P-eIF2α) were examined b y immunoblot analysis (I). P-PERK and P-eIF2α showed transient expression patterns which reac hed the peak level at day 3. Transcriptions of downstream targets of eIF2α were examined with real time PCR. ATF4 (D) was remarkably up-regulated from day 3, and CHOP showe d... of endoplasmic reticulum stress response (ERSR) genes were examined during the neuronal differentiation of rat fetal cortical precursor cells (rCPC) and rat pheochromocytoma PC12 cells. When rCPC were differentiated into neuronal cells for 7 days, early stem cell marker, nestin, expression was decreased from day 4, and neuronal markers such as neurofilament-L, -M and Tuj1 were increased after day 4. In this condition, expressions of BIP, ATF6, and phosphorylated PERK as well as their down stream... -
Lucerne transient streak virus; a Recently Detected Virus Infecting Alfafa (Medicago sativa) in Central Saudi Arabia
한국식물병리학회 The Plant Pathology Journal 10 Pages
한국식물병리학회 The Plant Pathology Journal 2017, 33권 1호 5 43-52 (10 pages)
CLL, chlorotic local lesions; M, mottle; Mo, mosaic; Y, yellowing; CS, chlorotic streaks; NLL, necrotic lo- cal lesions; C, crinkling; MC, marginal chlorosis; S, stunting. Table 3. Response of host range plant species by DAS-ELI- SA and dot blot hybridization after mechanical inoculation with Lucerne transient streak virus (LTSV) Host plant LTSV results ELISA Dot blot Chenopodium quinoa Lot #5... A survey was conducted to determine the status of Lucerne transient streak virus (LTSV) in three high-yielding alfalfa regions in central Saudi Arabia (Riyadh, Qassim, and Hail) during 2014. Three hundred and eight symptomatic alfalfa, and seven Sonchus oleraceus samples were collected. DAS-ELISA indicated that 59 of these samples were positive to LTSV. Two isolates of LTSV from each region were selected for molecular studies. RT-PCR confirmed the presence of LTSV in the selected samples using a... -
A Rice Gene Homologous to Arabidopsis AGD2-LIKE DEFENSE1 Participates in Disease Resistance Response against Infection with Magnaporthe oryzae
한국식물병리학회 The Plant Pathology Journal 6 Pages
한국식물병리학회 The Plant Pathology Journal 2016, 32권 4호 9 357-362 (6 pages)
et al., 2009; Livak and Schmittgen, 2001; Pfaff, 2001). Nucleotide sequenc- es of primers used in this study are presented in Table 1. A basic PR1, OsPR1b gene (Os01g0382000) was strongly transcribed in the leaves after M. oryzae infection (Fig. 1C), suggesting that the pathosystem between cv. Dongjin plant and M. oryzae KJ-105a isolate was sufficient to analyze gene expression and disease... ALD1 (ABERRANT GROWTH AND DEATH2 [AGD2]-LIKE DEFENSE1) is one of the key defense regulators in Arabidopsis thaliana and Nicotiana benthamiana. In these model plants, ALD1 is responsible for triggering basal defense response and systemic resistance against bacterial infection. As well ALD1 is involved in the production of pipecolic acid and an unidentified compound(s) for systemic resistance and priming syndrome, respectively. These previous studies proposed that ALD1 is a potential candidate for... -
The neuroprotective mechanism of ampicillin in a mouse model of transient forebrain ischemia
Kyung-EonLee, Kyung-OkCho, Yun-SikChoi, SeongYunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.2 7 185-192 (8 pages)
Physiol Pharmacol. 2015;19:177-181. 4. Melani A, Dettori I, Corti F, Cellai L, Pedata F. Time-course of protection by the selective A2A receptor antagonist SCH58261 after transient focal cerebral ischemia. Neurol Sci. 2015;36:1441-1448. 5. Yu G, Wu F, Wang ES. BQ-869, a novel NMDA receptor antagonist, protects against excitotoxicity and attenuates cerebral ischemic injury in stroke. Int J Clin... a mouse model of transient global forebrain ischemia. Male C57BL/6 mice were anesthetized with halothane and subjected to bilateral common carotid artery occlusion for 40 min. Before transient forebrain ischemia, ampicillin (200 mg/kg, intraperitoneally [i.p.]) or penicillin G (6,000 U/kg or 20,000 U/kg, i.p.) was administered daily for 5 days. The pretreatment with ampicillin but not with penicillin G significantly attenuated neuronal damage in the hippocampal CA1 subfield. Mechanistically, the... -
The effects of therapeutic ultrasound stimulation on the inflammation cytokine in rat articular chondrocytes
Eun-Jung Kim, Su-jin Hwang, Gye-Yeop Kim 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2013, 제 2권 제 1호 4 21-26 (6 pages)
in response to stimulation with LPS in rat chondrocyte. These cytokines downregulate the enzy- matic antioxidant defenses in chondrocytes, resulting in the transient accumulation of LPS [36,37]. Inflammatory medi- ator can directly sensitize nociceptors and increase neuronal excitation and sensitivity [38]. Therefore, cytokine level downregulation is important to pain control. Our study... Objective: The aim of this study was to investigate the effect of therapeutic ultrasound (US) of cell viability and inflammatory cytokine in rat articular chondrocyte cultures stimulated with lipopolysaccharide (LPS). Design: One group pretest-posttest design. Methods: Cultured chondrocytes were treated with US and/or LPS and assessed for viability, Tumor necrosis factor (TNF)-α and Interleukin (IL)-1 production. Results: Oxidative stress was induced in rat chondrocytes with LPS. The cell... -
The effect of coenzyme Q10 on endothelial function in a young population
Jerrold Petrofsky, M. Laymona, H. Lee, E. Hernandez, D. Dequine, L. Thorsen, R. Lovell, J. Andrade 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2012, 제 1권 제 1호 2 6-12 (7 pages)
This causes an in- crease in potassium permeability in vascular smooth muscle surrounding the endothelial cell [22,33,35]. Relaxation of vascular smooth muscle then increases blood flow. But this response only lasts a few minutes. The sustained response to increasing temperature in the skin is mediated by transient receptor potential vanilloid type-4 (TRPV-4) voltage gated calcium channels ... blood flow in the forearm skin and the blood flow response to 4 minutes of vascular occlusion and the response to local heat (42oC) for 6 minutes. Results: The results showed that, for this population, there was no difference in the response to heat. However, the response to occlusion was improved after administration of CoQ10. Conclusions: It would appear that in a young population CoQ10 has no effect on the nitric oxide vasodilator pathway in skin but does influence other vasodilator pathways.