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Protective and therapeutic effects of an extract mixture of alder tree, labiate herb, milk thistle green bean-rice bran fermentation, and turnip against ethanol-induced toxicity in the rat
Min-Won Baek, Seung-Hyeok Seok, Hui-Young Lee, Dong Jae Kim, Byoung-Hee Lee, Young-Tae Ahn, Kwang-Sei Lim, Chul-Sung Huh, Jae-Ha 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 1호 5 31-37 (7 pages)
2 ×) of herbal extract mixture and yogurt were used. The herbal extract mixture 1 × with the dose of the yogurt additive, was expected to be put on the market. The herbal extract mixture 2 × had a two-fold concentration. The commercial drug (Legalon; Bukwang Pharm, Korea) consisted of sylibin (Carduus marianus extract) was used as a control. The ethanol purchased from the Sigma-Aldrich... and histopathological analysis. It was also shown that co-treatment with herbal extract mixture and yogurt against a triple oral dose of ethanol (2 g/kg body weight, over one week) provided protection against ethanol toxicity. After the initial set of experiments, the herbal extract mixture and yogurt treatments were extended for three more weeks. When compared to the positive control, further treatment with both the herbal extract and yogurt significantly reduced liver injury and resulted in a... -
Guanosine 5'-monophosphate-chelated calcium and iron feed additives maintains egg production and prevents Salmonella Gallinarum in experimentally infected layers
Hye-Ji Noh, HeeKyong Kim, Su Jeong Heo, Hyang Hyun Cho, Hong Bum Koh 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 3호 5 291-297 (7 pages)
egg production rate and broken eggs [11,31]. Interestingly, the infected CaFe-GMP additive group retained a normal egg production rate and broken eggs were not observed during the experimental period. Similarly, others have shown that dietary supplementation with a Fe-soy proteinate effectively improved egg quality [28], and dietary supplementation of an organic mineral mixture increased the... We evaluated the effects of guanosine 5′-monophosphate (GMP)-chelated calcium and iron (CaFe-GMP) on health and egg quality in layers experimentally infected with Salmonella Gallinarum. In this study, a CaFe-GMP feed additive was added to a commercial layer feed and fed to layers over a four-week period. All were inoculated with Salmonella Gallinarum. Body weight, mortality, clinical symptoms, and poultry production including feed intake, egg production, egg loss, and feed conversion rate were... -
Predominant D1 Receptors Involvement in the Over-expression of CART Peptides after Repeated Cocaine Administration
ZhenzhenHu, Eun-HyeOh, YeonBokChung, JinTaeHong, Ki-WanOh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.2 2 89-97 (9 pages)
an additive effect are that the D 1R, but not the D2R, is a critical regulator for gene expressions during the development of BS. We agree with the previous studies that D 2R antagonists are less effective in inhibiting the psychostimulants-induced pCREB than D1R antagonists [37,38]. This possibility is also supported by Bertran-Gonzalez et al. [6] who reported that early ERK activation in... The aim of this study was to investigate the involvement of dopaminergic receptors (DR) in behavioral sensitization, as measured by locomotor activity, and the over-expression of cocaine- and amphetamine-regulated transcript (CART) peptides after repeated administration of cocaine in mice. Repeated administrations of cocaine induced behavioral sensitization and CART over-expression in mice. The levels of striatal CART mRNA were significantly increased on the 3rd day. CART peptides were... -
Differential Effects of Tautomycetin and Its Derivatives on Protein Phosphatase Inhibition, Immunosuppressive Function and Antitumor Activity
MingshanNiu, YanSun, BoLiu, LiTang, RongguoQiu 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.2 10 145-151 (7 pages)
ades of these molecular targets may produce additive and even synergistic cytostatic effects. Identification of poten- tial novel targets responsible for different effects of TMC is underway. ACKNOWLEDGEMENTS This research was supported by National Natural Science Funds for Distinguished Young Scholar 30688003 to L. Tang. We thank Dr. Yongliang Ya ng for critical reading of the manuscript.... In the present work, we studied the structure-activity relationship (SAR) of tautomycetin (TMC) and its derivatives. Further, we demonstrated the correlation between the immunosuppressive fuction, anticancer activity and protein phosphatase type 1 (PP1) inhibition of TMC and its derivatives. We have prepared some TMC derivatives via combinatorial biosynthesis, isolation from fermentation broth or chemical degradation of TMC. We found that the immunosuppressive activity was correlated with... -
The Neuroprotective Potential of Cyanidin-3-glucoside Fraction Extracted from Mulberry Following Oxygen-glucose Deprivation
MohammadIqbalHossainBhuiyan, Hyun-BokKim, SeongYunKim, Kyung-OkCho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.6 6 353-362 (10 pages)
at a relatively lower concen- tration. However, the additive neuroprotective effect of oth- er component(s) present in crude C3G fraction cannot be excluded, given that the mulberry C3G fraction used in our study was not 100% pure. Glutamate-induced excitotoxi city can also contribute to neuronal damage and degeneration following in vivo cere- bral ischemia [39,40] and in vitro hypoxia/ischemia... In this study, cyanidin-3-glucoside (C3G) fraction extracted from the mulberry fruit (Morus alba L.) was investigated for its neuroprotective effects against oxygen-glucose deprivation (OGD) and glutamate-induced cell death in rat primary cortical neurons. Cell membrane damage and mitochondrial function were assessed by LDH release and MTT reduction assays, respectively. A time-course study of OGD-induced cell death of primary cortical neurons at 7 days in vitro (DIV) indicated that neuronal... -
Rapid and Sensitive Detection of Lettuce Necrotic Yellows Virus and Cucumber Mosaic Virus Infecting Lettuce (Lactuca sativa L.) by Reverse Transcription Loop-Mediated Isothermal Amplification
Yubao Zhang, Zhongkui Xie, John D Fletcher, Yajun Wang, Ruoyu Wang, Zhihong Guo, Yuhui He 한국식물병리학회 The Plant Pathology Journal 11 Pages
한국식물병리학회 The Plant Pathology Journal 2020, 36권 1호 7 76-86 (11 pages)
the LAMP reaction mixture (often referred to as RT-LAMP) (Bhat et al., 2013). Both LAMP and RT-LAMP use four to six primers along with DNA polymerization with strand-displacing activity to generate amplification products. These products can be vi- sually detected using agarose gel electrophoresis or through color changes visualized by adding SYBR Green I, ethid- ium bromide or calcein to the... Cucumber mosaic virus (CMV) is damaging to the growth and quality of lettuce crops in Lanzhou, China. Recently, however, for the first time an isolate of lettuce necrotic yellows virus (LNYV) has been detected in lettuce crops in China, and there is concern that this virus may also pose a threat to lettuce production in China. Consequently, there is a need to develop a rapid and efficient detection method to accurately identify LNYV and CMV infections and help limit their spread. Reverse... -
Mechanical properties of epoxy composites reinforced with ammonia-treated graphene oxides
Mi-Seon Park, Sangmin Lee, Young-Seak Lee 한국탄소학회 Carbon Letters 7 Pages
한국탄소학회 Carbon Letters 2017, Vol.21 1 1-7 (7 pages)
the mixture. The temperature of the suspension was increased to 70°C, and the suspension was then stirred for 12 h. After the addi- tion of distilled water (400 mL), the suspension was stirred for an additional 12 h. Hydrogen peroxide (8 mL, 34.5%) was then slowly added, and vigorous bubbles appeared as the color of the suspension changed from dark brown to yellow. The suspension was then... The effects of ammonia-treated graphene oxide (GO) on composites based on epoxy resin were investigated. Ammonia solutions of different concentrations (14?28%) were used to modify GO. Nitrogen functional groups were introduced on the GO surfaces without significant structural changes. The ammonia-treated GO-based epoxy composites exhibited interesting changes in their mechanical properties related to the presence of nitrogen functional groups, particularly amine (C-NH2) groups on the GO... -
Effects of an inorganic ammonium salt treatment on the flame-retardant performance of lyocell fibers
Hyeong Gi Kim, Byong Chol Bai, Se Jin In, Young-Seak Lee 한국탄소학회 Carbon Letters 5 Pages
한국탄소학회 Carbon Letters 2016, Vol.17 No.1 11 74-78 (5 pages)
in Table 1. All of the steps of the IDT decreased with the (NH4)2SO4/ NH4Cl additive but increased with the heating rate. This was attributed to the easy thermal decomposition by the dehydration of the lyocell fbers catalyzed by the phosphoric acid byproduct, which also contributed to quenching the pyrolysis system. At lower temperature, the decomposition reactions became slow, and thus a... -
색채 잔상 지각에서 배경 색에 의해 유도된 색의 가산 혼합 현상 탐구
김선아, 정찬섭, Kim. Sun Ah, Chung. Chan-Sup 한국인지과학회 인지과학 10 Pages
한국인지과학회 인지과학 2004, Vol.15 No.4 21-30 (10 pages)
등광도인 두 색으로 이루어진 배경(적색/녹색, 청색/녹색, 혹은 청색/황색 배경) 위의 중앙에 회색 원이 놓일 때 이 회색 원에 대한 잔상은 본래의 두 배경 색에 대한 가산 혼합 색인 것으로 나타났다. 잔상에 나타난 이러한 흔한 색은 두 배경 색의 광도가 다를 때에도 나타났고, 회색 인의 크기가 증가하였을 때에도 나타났다. 나타난 잔상의 채도는 순응 배경 자극의 평균 광도 값이 증가할수록, 그리고 회색 원의 크기가 감소할수록 증가하는 것으로 나타났다. 하지만 검사 자극의 중앙에 유채색 혹은 무채색의 경계선이 놓일 때 순응... -
Antioxidant Effects of Pyrogallol in Neural Cells and Mice Brain
Jisub Moon, Heesun Gwak, Tae-Hee Lee, Eun Suk An, Yun-Bae Kim, Dongsun Park 한국교원대학교 뇌기반교육연구소 Brain, Digital, & Learning 12 Pages
한국교원대학교 뇌기반교육연구소 Brain, Digital, & Learning 2019, 제 9권 제 3호 2 113-124 (12 pages)
color additive. However, the results of the current study show that pyrogallol can also up-regulate antioxidant enzyme mRNA levels (and presumably activities) and is relatively non-toxic, thus potentially useful to treat neurodegenerative diseases. Acknowledgments This work was supported by the 2017 New Professor Research Grant funded by the Korea National University of Education. ..PAGE:10 Moon,... Polyphenols can easily react with reactive oxygen species (ROS) resulting in powerful antioxidant activity. Pyrogallol is a polyphenol found in a variety of fruits and vegetables. Therefore, plants containing pyrogallol can be used for their antioxidant, anti-bacterial, anti-fungal, anti-allergic, and anti-inflammatory properties. However, its effectiveness as an antioxidant is still a matter of debate because pyrogallol is also a superoxide anion generator and induces superoxide anion-mediated...