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전체 선택해제
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본문검색 결과만 보기
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Concentrations of strontium, barium, cadmium, copper, zinc, manganese, chromium, antimony, selenium, and lead in the liver and kidneys of dogs according to age, gender, and the occurrence of chronic kidney disease
Nadine Paßlack, Barbara Mainzer, Monika Lahrssen-Wiederholt, Helmut Schafft, Richard Palavinskas, Angele Breithaupt, Ju 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 1호 8 57-66 (10 pages)
KL. Hepatic copper concentrations in Labrador Retrievers with and without chronic hepatitis: 72 cases (1980-2010). J Am Vet Med Assoc 2013, 242, 372-380. 15. Kane E, Morris G, Rogers QR, Ihrke PJ, Cupps PT. Zinc deficiency in the cat. J Nutr 1981, 111, 488-495. 16. Keen CR, Lonnerdal B, Fisher GL. Age-related variations in hepatic iron, copper, zinc and selenium concentrations in beagles. Am... chronic kidney disease (CKD). Tissues from 50 dogs were analyzed using inductively coupled plasma mass spectrometry. Cu, Zn, and Mn levels were highest in the liver followed by the renal cortex and renal medulla. The highest Sr, Cd, and Se concentrations were measured in the renal cortex while lower levels were found in the renal medulla and liver. Female dogs had higher tissue concentrations of Sr (liver and renal medulla), Cd (liver), Zn (liver and renal cortex), Cr... -
[3H]MK-801 Binding to the Synaptic Membranes of Rat Forebrains Age-related Regulation by Glutamate, Glycine and Spermine
JungsookCho, JaeYangKong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 1 117-125 (9 pages)
J Appl Pharmacol 4: 196 -201， 1996 Cohen SA and Mueller WE: Age-related a1terations of NMDA receptor properties in the mouse forebrain partial restoration by chronic phosphatidylserine treat ment. Brain Res 584: 174-180， 1992 Collingridge GL， Kehl SJ， McLennan H: Excitatory amino 3cids in synaptic transmission in the Schaffer collatcral commissural pathway of thc rat hippocam pus. J... (NMDA) receptor-mediated glutamatergic neurotransmission is involved in synaptic plasticity, developmental processes, learning and memory and many neuropathological disorders including age-related diseases. In the present study, regulation of the NMDA receptor properties by various ligands was investigated using [3H]MK-801 binding studies in the synaptic membranes of young and aged rat forebrains. The binding in the presence of glutamate and glycine increased dramatically with growth between 1... -
Relationships between upper extremity performance and unified Parkinson’s disease rating scale-motor exam
Won-jeong Hwang, Su-jin Hwang, Kyoung-suk Lee, Yi-jung Chung 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2013, 제 2권 제 2호 7 99-103 (5 pages)
both upper extremities. This is because our potential limitation of the study was a relatively small sample. The results of this study cannot necessarily be gen- eralized to rehabilitation of more chronic and severe states of PD, because all of the participants had Hoehn and Yahr stages II to III PD. In future studies, ADL and quality of life will be measured for investigation of relationship... as a quantifying clinical tool of upper extremity function in persons with Parkinson’s disease. Design: Cross-sectional study. Methods: Thirty-two idiopathic Parkinson’s Disease persons participated in this study. To investigate the relationship between the UPDRS-motor exam, Box and Block test (BBT), and Action Research Arm Test (ARAT) by two physical therapists. The examination took up to 1 hour, and the participants were invited to rest between each clinical measure in order to minimize the... -
GPS Collars of Cloven-Hoofed Livestock Movement Patterns and Prevention of Foot and Mouth Disease in Eastern Mongolia
Suvd Erdene Tseren Ochir, Oun Kyong Moon, Woo seog Jeong, Hac hung Yoon, Jida Choi, Yong Myong Kang, Erdene Ochir Tseren Ochir, Ganzori 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 174 426-427 (2 pages)
of fatal, neurodegenerative disorders including human Creuzfeldt-Jakob disease, bovine spongiform encephalopathy, ovine scrapie and chronic wasting disease of North American deer and elk. Polymorphisms in the PRNP gene can lead to different prion forms that moderate individual susceptibility to and progression of TSE infection. The aim of this study was to identify the PRNP polymorphism... -
Retrospective study of degenerative mitral valve disease in small-breed dogs: survival and prognostic variables
Hyun-Tae Kim, Sei-Myoung Han, Woo-Jin Song, Boeun Kim, Mincheol Choi, Junghee Yoon, Hwa-Young Youn 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 3호 14 369-376 (8 pages)
kg, were included in this study. Physical, chest radiograph, and echocardiographic examinations were performed for all dogs. Some dogs with concurrent disease such as chronic kidney disease, liver failure or hormonal disease (e.g., Cushing’s disease, diabetes mellitus, or hypothyroidism) were included only if the condition was well managed with medicinal therapy. The numbers of dogs showing... Small-breed dogs (n = 168; weight ＜ 15 kg) diagnosed with myxomatous mitral valve degeneration based on a routine clinical examination, radiology, electrocardiography, and echocardiography at the Seoul National University Veterinary Medical Teaching Hospital were included in this study. Survival periods were determined, and there were significant differences in survival rates among the three International Small Animal Cardiac Health Council classes. The mean follow-up period was 14.3 ± 12.1... -
Neuronal maturation in the hippocampal dentate gyrus via chronic oral administration of Artemisa annua extract is independent of cyclooxygenase 2 signaling pathway in diet-induced obesity mouse model
Hye Kyung Baek, Pan Soo Kim, Ji Ae Song, Dong-Hwa Choi, Do Eun Kim, Seung Il Oh, Sang-Kyu Park, Sung-Jo Kim, Ki-Duk Song, In Koo 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 2호 1 119-127 (9 pages)
western blotting for COX-2 and Iba-1, in order to assess correlations between systemic inflammation (interleukin-6) and food type. Additionally, we tested the effect of AA in an Alzheimer’s disease model of Caenorhabditis elegans and uncovered a potential benefit. The results show that chronic AA dosing significantly increases neuronal maturation, particularly in the high-fat diet group. This... Therefore, the present study was undertaken to assess whether AA increases neuronal maturation by reducing inflammatory responses, such as those mediated by cyclooxygenase 2 (COX-2). Mice were fed normal chow or a high-fat diet with or without chronic daily oral administration of AA extract (0.2 g/10 mL/kg) for 4 weeks; then, changes in their hippocampal dentate gyri were measured via immunohistochemistry/immunofluorescence staining for bromodexoxyuridine, doublecortin, and neuronal nuclei,... -
Molecular-level evaluation of selected periodontal pathogens from subgingival regions in canines and humans with periodontal disease
Magdalena Goły?ska, Izabela Polkowska, Małgorzata Bartoszcze-Tomaszewska, Aleksandra Sobczy?ska-Rak, Łukasz Matuszewski 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 1호 7 51-58 (8 pages)
identified Tannerella forsythia and P as the predominant pathogens in the course of periodontitis in humans. In contrast, Al-Hebsi et al. [4], in their study of bacterial microflora in humans with chronic periodontitis, reported a low correlation between Pgingivalis and periodontal disease when compared to the correlations with other evaluated bacteria; those results contradict the results i... Dogs commonly serve as a model for various human conditions, including periodontal diseases. The aim of this study was to identify the anaerobic bacteria that colonize the subgingival areas in dogs and humans by using rapid real-time polymerase chain reaction (RT-PCR)-based tests and to compare the results obtained in each species. Bacterial microflora evaluations, both quantitative and qualitative, were performed by applying ready-made tests on twelve dogs and twelve humans. Five samples were... -
Effects of cetirizine in dogs with chronic atopic dermatitis: a randomized, double blind, placebo-controlled trial
Yun-Hsia Hsiao, Charles Chen, Ton Willemse 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 4호 14 549-553 (5 pages)
sensitivity of 85% and a specificity of 79% to differentiate dogs with atopic dermatitis (AD) from those with chronic or recurrent pruritus without AD. Effects of cetirizine in dogs with chronic atopic dermatitis: a randomized, double blind, placebo-controlled trial Yun-Hsia Hsiao 1,*, Charles Chen 1 , Ton Willemse 2 1Asian Referral Center, Taipei 106, Taiwan 2 Faculty of Veterinary Medicine,... blind, placebo-controlled study, without concomitant medication. The effects were evaluated using a pruritus visual analog scale at the start (day 0) and at day 14. After 14 days, cetirizine clearly had no effect on the pruritus in dogs with chronic AD, and there was no significant difference between groups. These findings indicated that cetirizine (and likely H1 histamine receptor antagonists in general) should not be recommended for the control of pruritus in dogs with long term allergies. -
Frequencies of Micronuclei in Peripheral Lymphocytes in Korean Populations after Chronic Low-dose Radiation Exposure
Mi-Young An and Tae-Hwan Kim 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 3호 11 213-218 (6 pages)
or even until recently, had not developed any recognizable and reliable techniques for measuring chronic low-dose exposure below background level 8-11 . Accordingly, to determine the usefulness of MN assay as a reliable biomarker for monitoring chromosome damage of peripheral lymphocytes in human populations following chronic low-dose exposure to ionizing radiation below background levels, the... The purpose of this study was to estimate predictive markers of intrinsic radiosensitivity in individuals who were exposed to occupational or environmental radiation. Throughout this process, the actual biohazard risks and base-line chromosome damage were evaluated in human population. Further studies were carried out to provide evidence for the existence of individual variations in age-dependent responses through micronuclei (MN) assay. Spontaneous frequencies not only vary greatly between... -
Allogeneic clonal mesenchymal stem cell therapy for refractory graft-versus-host disease to standard treatment: a phase I study
HyeonGyuYi, Seung-AhYahng, InhoKim, Je-HwanLee, Chang-KiMin, JunHyungKim, ChulSooKim, SunU.Song 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.1 8 63-67 (5 pages)
Rasmusson I, Sundberg B, Gotherstrom C, Hassan M, Uzunel M, Ringden O. Treatment of severe acute graft-versus- host disease with third party haploidentical mesenchymal stem cells. Lancet. 2004;363:1439-1441. 7. Herrmann R, Sturm M, Shaw K, Purtill D, Cooney J, Wright M, Phillips M, Cannell P. Mesenchymal stromal cell therapy for steroid- refractory acute and chronic graft versus host disease: a... (3/11 patients). The only one adverse drug reaction related to cMSC administration was grade 2 myalgia in one patient. Treatment response was observed in four patients: one with acute GVHD (partial response) and three with chronic GVHD. The other chronic patients maintained stable disease during the observation period. This study demonstrates single cMSC infusion to have an acceptable safety profile and promising efficacy, suggesting that we can proceed with the next stage of the clinical trial.