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Pretreatment of Albino Rats with Methanolic Fruit Extract of Randia Dumetorum (L.) Protects against Alcohol Induced Liver Damage
ArshadAliNoorani, MohanK.Kale 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.2 7 125-130 (6 pages)
Albino Rats with Methanolic Fruit Extract of Randia Dumetorum (L.) Protects against Alcohol Induced Liver Damage Arshad Ali Noorani 1 , and Mohan K. Kale 2 1Department of Pharmacology, Mandsaur Institute of Pharmacy, MIT Campus, Mandsaur 458-001, Madhya Pradesh, 2Department of Pharmacology, Sharad Pawar College of Pharmacy, Nagpur 441-110, Maharashtra, India Alcohol abuse and its medical and... Alcohol abuse and its medical and social consequences are a major health problem in many areas of the world. The present study was conducted to evaluate the protective effect of methanolic fruit extract of Randia dumetorum (L.) on alcohol-induced liver damage in rats. Rats were divided into five different groups (n=6), group I served as a control, group II received ethanol (3 ml/100 g/day p.o.), group III served as standard group and received silymarin (50 mg/kg p.o.), group IV and V served as... -
Water and oxygen permeation through transparent ethylene vinyl alcohol/(graphene oxide) membranes
Hye Min Kim, Heon Sang Lee 한국탄소학회 Carbon Letters 7 Pages
한국탄소학회 Carbon Letters 2014, Vol.15 No.1 7 50-56 (7 pages)
nm. The EVOH/GO membranes exhibited 100 times better (water vapor)/(oxygen) selectivity performance than pure EVOH membrane. Key words: graphene oxide, ethylene vinyl alcohol, permeability, selectivity, water vapor 1. Introduction Ethylene vinyl alcohol (EVOH) is one of the best known oxygen barrier materials in use today, with excellent gas barrier properties, processability, and sensitivity to... prepared ethylene vinyl alcohol (EVOH)/graphene oxide (GO) membranes by solution casting method. X-ray diffraction analysis showed that GOs were fully exfoliated in the EVOH/GO membrane. The glass transition temperatures of EVOH were increased by adding GOs into EVOH. The melting temperatures of EVOH/GO composites were decreased by adding GOs into EVOH, indicating that GOs may inhibit the crystallization of EVOH during non-isothermal crystallization. However, the equilibrium melting temperatures... -
Can prosthetic limbs made too quickly cause kidney damage?
Jerrold S. Petrofsky, Mary Browne, Mahyar Jamshidi, Anthony Libo-on, Ha-neul Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2014, 제 3권 제 2호 7 119-124 (6 pages)
of dimethyl sulfoxide, polyethylene glycol 400, dimethylforma- mide, absolute ethanol, and benzyl alcohol in inbred mouse strains. Arzneimittelforschung 1994;44:566-70. 34. Matanoski GM, Tao XG. Styrene exposure and ischemic heart disease: a case-cohort study. Am J Epidemiol 2003;158:988-95. 35. Matanoski GM, Tao X. Case-cohort study of styrene exposure and ischemic heart disease.Res Rep Health... Objective: The use of chemicals for building prosthetic sockets present the possibility of being hazardous and unsafe due to off-gassing. The purpose of the present study was to investigate if freshly made materials used in prosthetic sockets causes off-gassing that would penetrate the skin and cause damage to the kidneys or blood. Design: Cross-sectional study. Methods: In this research, the off-gassing effects during the initial curing process of styrene monomer, vinyl ester resin, epoxy... -
Hair Growth Effect of Eclipta Prostrata L. onC57BL/6N Mice
Jun Kyu Kim, Sung Min Cho, Won Kyung Rim, Young jae Lee, Chang Hoon Han 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 299 355-356 (2 pages)
..PAGE:1 Vol. 56, No. 3 October 355 and acetaldehyde concentrations of mice pre-treated with alcohol. In addition, the differential gene expression patterns in mice liver were analyzed through cDNA microarray analysis to observe the effects of HD or SHV on gene expression related to alcohol metabolism. Results: Both HD and SHV showed DPPH radical scavenging activities and showed... -
Efficacy of horse chestnut leaf extract ALH-L1005 as a matrix metalloproteinase inhibitor in ligature-induced periodontitis in canine model
Se Eun Kim, Tae Hyun Kim, Shin Ae Park, Won Tae Kim, Young Woo Park, Jae Sang Ahn, Manbok Jeong, Min-Young Kim, Kangmoon Seo 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 2호 15 245-251 (7 pages)
6 5 20 *25% aqueous alcohol extract of horse chestnut leaf ( Aesculus hippocastanum L.). injection and are used in the treatment of edema and venous insufficiency [2]. The purpose of this study was to assess the clinical effect of the horse chestnut leaf extract ALH-L1005 as an MMP inhibitor on periodontitis progression in beagle dogs with experimentally induced periodontitis. Materials and... Matrix metalloproteinases (MMPs) are the main proteinases associated with periodontal tissue destruction and remodeling. Therefore, inhibition of host-derived MMPs has a key role in the prevention and reduction of periodontitis progression. Horse chestnut (Aesculus hippocastanum L.) extracts have been used as treatments for inflammatory disease, traditionally. This study assessed the clinical effect as a MMP inhibitor of horse chestnut leaf extract ALH-L1005 on periodontitis. ALH-L1005 was... -
Aristolochia manshuriensis Kom ethyl acetate extract protects against high-fat diet-induced non-alcoholic steatohepatitis by regulating kinase phosphorylation in mouse
Dong Hoon Kwak, Ji-Su Kim, Kyu-Tae Chang, Young-Kug Choo 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 3호 3 279-287 (9 pages)
(ND) group received a normal diet. The animals were casually separated into four groups (n = 10). Specifically, the ND group received a normal diet, the HFD group received HFD alone, the butyl alcohol (BuOH) group received HFD plus BuOH extract of AMK (62.5 mg/kg/day, orally), and the EtOAc extract group received the HFD plus the AMK EtOAc extract (2.5 mg/kg/day). After 15 weeks, the mice... Aristolochia manshuriensis Kom (AMK) is an herb used as a traditional medicine; however, it causes side effects such as nephrotoxicity and carcinogenicity. Nevertheless, AMK can be applied in specific ways medicinally, including via ingestion of low doses for short periods of time. Non-alcoholic steatohepatitis (NASH) induced the hepatocyte injury and inflammation. The protective effects of AMK against NASH are unclear; therefore, in this study, the protective effects of AMK ethyl acetate... -
A simplified one-step nuclear transfer procedure alters the gene expression patterns and developmental potential of cloned porcine embryos
Sang Kyu Park, Sangho Roh*, Jong-Im Park* 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 1호 8 73-80 (8 pages)
and 0.1% (w/v) polyvinyl alcohol (PVA) [3]. Preparation of nuclear donor cells Fibroblasts were recovered from one porcine conceptus, which was assumed to be between embryonic days 28 to 39 in age, collected from a local slaughterhouse. The head, extremities, and internal organs were removed, and the remaining tissues were cut into small pieces (less than 1mm cube). Cells were dispersed by... Various somatic cell nuclear transfer (SCNT) techniques for mammalian species have been developed to adjust species-specific procedures to oocyte-associated differences among species. Species-specific SCNT protocols may result in different expression levels of developmentally important genes that may affect embryonic development and pregnancy. In the present study, porcine oocytes were treated with demecolcine that facilitated enucleation with protruding genetic material. Enucleation and donor... -
Elm tree bark extract inhibits HepG2 hepatic cancer cell growth via pro-apoptotic activity
Tae Myoung Kim, Sang-Kyung Shin, Tae-Wang Kim, So-Young Youm, Dae Joong Kim, Byeongwoo Ahn* 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2012, 제 13권 제 1호 2 7-13 (7 pages)
[19]. In addition to viral infections, several etiological risk factors have been identified including alcohol abuse, expose to aflatoxin B1, and nonalcoholic fatty liver change [16]. HCC frequently arises in patients with liver cirrhosis, the result of a complex pathogenesis involving chronic hepatitis, necrosis, and regenerative fibrosis. Since terminal stage HCC can rarely be cured by... Control of inflammation is widely accepted as an important strategy for cancer chemoprevention. Anti-inflammatory effects of bark extracts of elm tree (BEE) have been amply reported. Therefore, BEE may be a good candidate cancer chemopreventive agent. Considering the high incidence of hepatic cancer and limited therapeutic approaches for treating this disease, it is important to develop liver cancer-specific chemopreventive agents. To evaluate the chemopreventive potential of BEE, we... -
Fast neutron irradiation deteriorates hippocampus-related memory ability in adult mice
Miyoung Yang, Hwanseong Kim, Juhwan Kim, Sung-Ho Kim, Jong-Choon Kim, Chun-Sik Bae, Joong-Sun Kim, Taekyun Shin, Changjong Moon* 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2012, 제 13권 제 1호 1 1-6 (6 pages)
buffer (0.01 M, pH 6.0) and heated in an autoclave for 10 min. All subsequent steps were performed at room temperature. The sections were treated with 0.3% hydro- gen peroxide in methyl alcohol for 20 min to block endogenous peroxidase activity. After three washes with PBS, the sections were blocked with 10% normal goat serum (Vector Laboratories, USA) in PBS for 1 h and then incubated for 2... Object recognition memory and contextual fear conditioning task performance in adult C57BL/6 mice exposed to cranial fast neutron irradiation (0.8 Gy) were examined to evaluate hippocampus-related behavioral dysfunction following acute exposure to relatively low doses of fast neutrons. In addition, hippocampal neurogenesis changes in adult murine brain after cranial irradiation were analyzed using the neurogenesis immunohistochemical markers Ki-67 and doublecortin (DCX). In the object...