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Nitric Oxide Plays an Important Role in β-Aminobutyric Acid-Induced Resistance to Botrytis cinerea in Tomato Plants
Rui Li, Jiping Sheng, Lin Shen 한국식물병리학회 The Plant Pathology Journal 12 Pages
한국식물병리학회 The Plant Pathology Journal 2020, 36권 2호 2 121-132 (12 pages)
way enzyme phenylalanine ammonia-lyase in the biosynthe- sis of phenylpropanoids. Mol. Plant 8:17-27. Zhang, X., Shen, L., Li, F., Meng, D. and and Sheng, J. 2011. Methyl salicylate-induced arginine catabolism is associated with up-regulation of polyamine and nitric oxide levels and improves chilling tolerance in cherry tomato fruit. J. Agric. Food Chem. 59:9351-9357. Zheng, Y., Hong, H., Chen... β-Aminobutyric acid (BABA) has consistently been reported to enhance plant immunity. However, the specific mechanisms and downstream components that mediate this resistance are not yet agreed upon. Nitric oxide (NO) is an important signal molecule involved in a diverse range of physiological processes, and whether NO is involved in BABA-induced resistance is interest- ing. In this study, treatment with BABA significantly increased NO accumulation and reduced the sensitivity to Botrytis cinerea... -
Evaluation of IGF-I levels and serum protein profiles of diabetic cats and dogs
Gulay Ciftci*, Gul Fatma Yarim 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2011, 제 12권 제 4호 4 325-331 (7 pages)
to increased protein catabolism [41,44] and hyperglycemia. Insulin is an anabolic agent and an important regulator of the growth hormone (GH) and insulin-like growth factors (IGF) [7]. The two major IGF-I and -II were found to be low molecular weight polypeptide hormones [34]. IGF-I is mainly synthesized in the liver, and the secretion of IGF-I was stimulated by growth hormone [38]. This... In this study, we measured the insulin-like growth factor (IGF)-I levels and evaluated the serum protein profiles of diabetic, insulin-treated, and healthy cats and dogs. The total IGF-I concentrations were 33.74 ± 3.4 ng/mL for normal, 25.8 ± 4.5 ng/mL for diabetic, and 180.4 ± 31.4 ng/mL for insulin-treated cats. IGF-I concentrations were 46.4 ± 6.6 ng/mL for normal, 25.1 ± 4.1 ng/mL for diabetic, and 303.0 ± 61.3 ng/mL for insulin-treated dogs. Total serum protein profiles were analyzed... -
Neuropharmacological effects of deltamethrin in rats
S. Manna, D. Bhattacharyya, T. K. Mandal, S. Dey 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 2호 7 133-136 (4 pages)
increased catabolism of GABA resulting in the inactivation of the Cl channel leading to excitation and convulsion. Deltamethrin increased the pentobarbitone induced sleeping time in rats. On the other hand, pentobarbitone reduced the CNS excitation symptoms caused by deltamethrin, which were corroborated by the findings reported Forshaw et al. [5], who showed that the voltage dependent chloride... a rotarod, the pentobarbitone-induced sleeping time and pentylenetetrazole (PTZ)-induced convulsion as well as the gamma aminobutyric acid (GABA) level. Albino Wistar rats were used as the experimental animals. Different neuropharmacological paradigms such as the motor co-ordination by the rotarod, pentobarbitone-induced sleeping time and the PTZinduced convulsion were examined after administering deltamethrin orally at two doses, 150 mg/kg (LD50) and 15 mg/kg (1/10 LD50). The GABA level in the... -
Time-dependent proteomic and genomic alterations in Toll-like receptor-4-activated human chondrocytes: increased expression of lamin A/C and annexins
SeungHeeHa, HyoungKyuKim, NguyenThiTuyetAnh, NariKim, KyungSooKo, ByoungDooRhee, JinHan 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 16 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.5 8 531-546 (16 pages)
on other signaling pathways mediating catabolism in the joint [5,6]. Several studies report that oncostatin M, fibronectin fragments, and retinoic acid induce chondrocyte-mediated catabolism, thereby reducing the aggrecan proteoglycan levels in cartilage [7-9]. Toll-like receptors (TLRs) have crucial functions in inflam- matory diseases [10-12] because they recognize pathogen- associated... Activation of Toll-like receptor-4 (TLR-4) in articular chondrocytes increases the catabolic compartment and leads to matrix degradation during the development of osteoarthritis. In this study, we determined the proteomic and genomic alterations in human chondrocytes during lipopolysaccharide (LPS)-induced inflammation to elucidate the underlying mechanisms and consequences of TLR-4 activation. Human chondrocytes were cultured with LPS for 12, 24,and 36 h to induce TLR-4 activation. The... -
Hypericum Perforatum Decreased Hippocampus TNF-α and Corticosterone Levels with No Effect on Kynurenine/Tryptophan Ratio in Bilateral Ovariectomized Rats
WesamMEl-Bakly, AmanyHHasanin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.3 6 233-239 (7 pages)
of depression probably through the catabolism of TRY along the KYN pathway [31]. A measurement for in vivo IDO ac- tivity is the ratio of product/ substrate (KYN/TRY). Thus, an increase in the ratio refl ects greater enzyme activity, a decrease indicates lower acti vity [32]. Shift from seroto- nin synthesis to KYN pathway leads to decrease the former level which is one of the well-known... The present study was designed to investigate the effect Hypericum Perforatum (HP), on behavioral changes, corticosterone, TNF-α levels and tryptophan metabolism and disposition in bilateral ovariectomized rats compared to 17α-ethinylestradiol. Behavioral analysis by measuring immobility time in forced swimming test and open field test, serum and hippocampal corticosterone and TNF-α along with hippocampal kynurenine/tryptophan ratio were determined in mature ovariectomized rats treated orally... -
Rifampicin Inhibits the LPS-induced Expression of Toll-like Receptor 2 via the Suppression of NF-κB DNA-binding Activity in RAW 264.7 Cells
SeongKeunKim, YoungMiKim, ChungEunYeum, Song-HyoJin, GueTaeChae, Seong-BeomLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.6 11 475-482 (8 pages)
a transcription factor for various genes, encoding xenobiotics metabolizing en- zymes and transporters, and is also implicated in lipid me- tabolism, where it inhibits lipid catabolism, increases fatty acid uptake and lipogenesis in the liver (Moreau et al., 2008). In addition, the activation of PXR shows anti-inflammatory effects. It has been reported that repression of the NF-κB signaling... Rifampicin is a macrocyclic antibiotic which is used extensively for treatment against Mycobacterium tuberculosis and other mycobacterial infections. Recently, a number of studies have focused on the immune-regulatory effects of rifampicin. Therefore, we hypothesized that rifampicin may influence the TLR2 expression in LPS-activated RAW 264.7 cells. In this study, we determined that rifampicin suppresses LPS-induced TLR2 mRNA expression. The down-regulation of TLR2 expression coincided with... -
Changes in the Endothelin-1-induced Contraction of Aorta in Streptozotocin-induced Diabetic Rats
HyunJooCheong, EunJinKim, SuJinKim, SunHeeLee, ByungYongRhim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.3 3 185-195 (11 pages)
of protein and lipid catabolism and induces the hypercholesterolemia， atherosc1erosis， hypertension and various cardiovascular diseases Corresponding to: Byung Yong Rhim， Department of Phara cology， Pusan National University College of Medicine， Pusan 602-739， Korea. (Tel) 82-51-240-7728， (Fax) 82-51-244-1036， (E-mail)byrhim@hyowon.pusan.ac.kr 185 (Lavy et al， 1973; Cohen et al，... Vascular diseases are significant complications of diabetes mellitus (DM), and the endothelial cells may play a pivotal role in the development of vascular disease in DM. Endothelin-1 (ET-1) released from endothelium is a potent vasoconstrictor peptide and circulating level of ET-1 is increased in a variety of disease states. The purpose of this study was to determine the changes of responsiveness to ET-1 in DM, and we experimented on the changes in the ET-1-induced contraction, levels of... -
Hydrocortisone, DHEA, Estradiol 및 Testosterone에 의하여 나타나는 마우스-간 및 소장 Polyamine 대사의 변동에 관한 연구
최상현(Sang-Hyun Choi), 전보권(Boe-Gwun Chun), 김남헌(Nam-Hun Kim), 천연숙(Yeon-Sook Chun) 대한약리학회 대한약리학잡지 10 Pages
대한약리학회 대한약리학잡지 1990, 제 26권 제 1호 8 67-76 (10 pages)
of polyamine catabolism, and that the HC-induced increase of the intestinal PT content is due partly to the inhibition of polyamine catabolism via DAO. Key Words: Polyamine metabolism, Diamine oxidase, Hydrocortisone, Estradiol, DHEA, Testosterone Abbreviations: HC, hydrocortisone; E2, estradiol; DHEA, dehydroepiandrosterone; TS, testosterone; PT, putrescine; SD, spermidine; SM, spermine; DAO,... 웅성-마우스의 고환을 diethyl ether 마취하에서 제거하고, 수종의 steroid 홀몬을 각각 매일 1회씩 4일간 피하주사하여, 간 및 소장의 polyamine 함량과 소장의 diamine oxidase (DAO) 활성도에 미치는 그들의 영향을 검색하였다. 1. Hydrocortisone succinate 50 mg/kg (HC) 및 dehydroepiandrosterone 250 mg/kg (DHEA)에 의하여, 소장의 putrescine (PT)은 유의하게 증가되었으나, spermidine (SD) 및 spermine (SM)은 별 영향을 받지 않았고, 간의 SD은 다소 증가되고, SM은 다소 감소 되었으나, PT은 별 변동을 보이지 않았다. 2.... -
정상 한국 성인의 공복시 및 식후 혈장 Secretin 농도
심여림(Sim, Yeo-Rim), 조양혁(Jo, Yang-Hyeok), 심상수(Sim, Sang-Soo), 남상채(Nam, Sang-Chae), 김명석(Kim, Myung-Suk) 대한생리학회 대한생리학회지 12 Pages
대한생리학회 대한생리학회지 1985, 제 19권 제 2호 6 161-172 (12 pages)
gastric acid. Gut, 19: 812-818, 1978. Tai, H.-H. and W. Y. Chey: Rapid extraction of secretin from ptasma by XAD-2 resin and its application in the radioimmunoassay of secre- tin. Anal. Biochem., 87:376-385, 1978. Thompson, J.C., O.L. Llanos, A. Schafmayer, R. K. Teichman and P.L. Rayford: Mechanisms of release and catabolism of secretin. In: Gut Hormones, edited by S.R. Bloom, Edinburgh:... 한국의 정상 성인 20 명에서 공복시 및 음식물 섭취후의 철장 secretin농도를 방사면역 측정법(radioimmunoassay)으로 다음과 같이 측정하였다. 20명중 12명은 단백질 음식물인 햄버거와 쌀밥을 일주일 간격으로 섭취하였다. 햄버거 섭취 추 평균 혈장 secretin농도(12 ~ 16 pg/ml)는 공복시의 평균 혈장 secretin농도(10 pg/m1 이하) 보다 유의하게 증가하였으며 그 증가가 오랫동안 지속하였다. 쌀밥의 섭취 후에는 혈장 secretin농도(9 ~ 13 pg/ml)가 공복시의 값보다 증가하는 경향이었으며, 단지 식후 30분의 값에서만 유의하게... -
Genome Wide Analysis of the Potato Soft Rot Pathogen Pectobacterium carotovorum Strain ICMP 5702 to Predict Novel Insights into Its Genetic Features
Tista Mallick, Rukmini Mishra, Sasmita Mohanty, Raj Kumar Joshi 한국식물병리학회 The Plant Pathology Journal 13 Pages
한국식물병리학회 The Plant Pathology Journal 2022, 38권 2호 4 102-114 (13 pages)
(n = 233, 5.15%) formed the largest group. The category for Cell motility, Transport and catabolism and Defence mechanisms represented the smallest groups with 51, 45, and 44 genes, respectively. Besides, the clusters for Amino acid transport and metabolism (n = 224, 4.95%), Carbo- hydrate transport and metabolism (n = 217, 4.80%), Co- enzyme transport and metabolism (n = 201, 4.44%), and... Pectobacterium carotovorum subsp. carotovorum (Pcc) is a gram-negative, broad host range bacterial pathogen which causes soft rot disease in potatoes as well as other vegetables worldwide. While Pectobacterium infection relies on the production of major cell wall degrading enzymes, other virulence factors and the mechanism of genetic adaptation of this pathogen is not yet clear. In the present study, we have performed an in-depth genome-wide characterization of Pcc strain ICMP5702 isolated from...