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A Review of the Potency of Plant Extracts and Compounds from Key Families as an Alternative to Synthetic Nematicides: History, Efficacy, and Current Developments
Abraham Okki Mwamula, Md. Faisal Kabir, DongWoon Lee 한국식물병리학회 The Plant Pathology Journal 25 Pages
한국식물병리학회 The Plant Pathology Journal 2022, 38권 2호 1 53-77 (25 pages)
a mixture of biologically active substanc- es, an attribute that reduces the possibilities of resistance development by the target nematodes (Dimetry, 2014; Sax- ena, 1983). The use of botanical nematicides has therefore been widely recommended as a suitable alternative of plant protection, with minimal side effects though there are some documented reports of undesirable effects on non-target... efficacy, potency and composition continue to persist, and commercialization of new botanical nematicides is still lagging. Herein, we have reviewed the history of botanical nematicides and regional progresses, the potency of the identified phytochemicals from the key important plant families, and deciphered some of the impediments involved in standardization of the active compounds in addition to the concerns over the safety of the purified compounds to non-target microbial communities. -
Development of Biomarkers Utilizing Variable Lymphocyte Receptors (VLRs) of Inshore Hagfish (Eptatretus burgeri) against Avian Influenza Virus
Se pyeong Im, Tae sung Jung, Jae sung Kim, Jung seok Lee, Si won Kiim, Tae hoon Kim, Jae wook Jung 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 춘계학술심포지움 42 158-159 (2 pages)
Mogg TJ, Burton GW. 2014. Biologically active polymers from spontaneous carotenoid oxidation: a new frontier in carotenoid activity. PLoS ONE 9 (10). [2] Cui B, Liu S, Wang Q, LinX. 2012. Effect of β-carotene on immunity function and tumour growth in hepatocellular carcinoma rats. Molecules 17: 8595-8603. [3] Shojadoost B, Vince AR, Prescott JF. 2012. The successful experimental induction... -
Association between endotoxin levels in dust from indoor swine housing environments and the immune responses of pigs
Katharine Roque, Kyung Min Shin, Ji Hoon Jo, Gyeong Dong Lim, Eun Seob Song, So Jung Shin, Ravi Gautam, Jae Hee Lee, Yeon Gyeong Kim, Ah 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 3호 2 331-338 (8 pages)
is a biologically active aerosol because it contains microorganisms such as bacteria, viruses, and fungi and their organic compounds, including endotoxins [22]. Endotoxins are one of the most ubiquitous organic compounds in agricultural settings. This is partly due to their heat resistance, which allows them to persist in the environment even under extreme conditions [21]. Airborne endotoxin... Indoor animal husbandry environments are inevitably contaminated with endotoxins. Endotoxin exposure is associated with various inflammatory illnesses in animals. This cross-sectional study evaluated the relationship between the degree of endotoxin exposure and the cellular and humoral immune profiles of fattening pigs. Blood samples were taken from the jugular vein of 47 pigs from ten pig farms in Korea. Whole blood cell counts and plasma immunoglobulin (Ig) classes were determined.... -
Effect of fermented soybean products intake on the overall immune safety and function in mice
Jae Hee Lee, Se Hee Paek, Hye Won Shin, Seung Yeon Lee, Byoung Seok Moon, Jung Eun Park, Gyeong Dong Lim, Chang Yul Kim, Yong He 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 1호 4 25-32 (8 pages)
the plain diet control, the fermented soy products could be responsible for the immune upregulation described above. Soybeans contain many biologically functional components including isoflavones, unsaturated fatty acids, and bioactive peptides, and the fermentation process is known to improve nutritional and functional properties of soybeans [6,21,34]. Among these components, isoflavone, a... Various functional activities have been reported for the fermented soybean products doenjang (DJ) and cheonggukjang (CGJ), although no systemic investigations of their immune functions have been conducted to date. We examined the effects of an experimental diet of DJ, CGJ, or a mixture of unfermented raw material for 4 weeks on overall immunity and immune safety in mice. No significant alterations were observed in peripheral or splenic immune cells among groups. Enhanced splenic natural killer... -
Anti-obesity activity of diglyceride containing conjugated linoleic acid in C57BL/6J ob/ob mice
Jin-Joo Hue, Ki Nam Lee, Jae-Hwang Jeong, Sang-Hwa Lee, Young Ho Lee, Seong-woon Jeong, Sang Yoon Nam, Young Won Yun, Beom Jun L 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2009, 제 10권 제 3호 3 189-195 (7 pages)
a low concentration of conjugated linoleic acid. Biosci Biotechnol Biochem 2001, 65, 2200-2204. 33. Pariza MW, Park Y, Cook M. The biologically active isomers of conjugated Linoleic acid. Prog Lipid Res 2001, 40, 283-298. 34. Parodi PW. Cows’ milk fat components as potential anticarcinogenic agents. J Nutr 1997, 127, 1055-1060. 35. Park Y, Albright KJ, Storkson JM, Liu W, Cook ME, Pariza... This study was to investigate the anti-obesity effects of diglyceride (DG)-conjugated linoleic acid (CLA) containing 22% CLA as fatty acids in C57BL/6J ob/ob male mice. There were four experimental groups including vehicle control, DG, CLA, and DG-CLA. The test solutions of 750 mg/kg dose were orally administered to the mice everyday for 5 weeks. CLA treatments significantly decreased mean body weight in the obese mice throughout the experimental period compared to the control (p ＜ 0.01). All... -
Additive Estrogenic Activities of the Binary Mixtures of Four Estrogenic Chemicals in Recombinant Yeast Expressing Human Estrogen Receptor
Yong Soon Lee, Kyung Sun Kang, Sung Dae Cho 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 1호 1 1-5 (5 pages)
system expressing hER. Acknowledgement This work was supported by the G-7 project from the Korean Ministry of Environment and partly by the Brain Korea 21 project. References 1. McLachlan, J.A., Functional toxicology: A new approach to detect biologically active xenobiotics. Environ Health Perspect 1993, 101 , 3 8 6 - 3 8 7 2. Colborn, T., Environmental estrogens: Health implications for humans... To evaluate the estrogenic activities of several chemicals such as 17beta-estradiol (E2), rho-nonylphenol, bisphenol A, butylparaben, and combinations of these chemicals, we used recombinant yeasts containing the human estrogen receptor [Saccharomyces cerevisiae ER + LYS 8127]. We evaluated E2 was most active in the recombinant yeast assay, followed by rho-nonylphenol, bisphenol A, butylparaben. The combinations of some concentrations of 17-estradiol as a strong estrogen and bisphenol A or... -
Epigallocatechin-3-Gallate (EGCG) Attenuates Traumatic Brain Injury by Inhibition of Edema Formation and Oxidative Stress
BoZhang, BingWang, ShuhuaCao, YongqiangWang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.6 3 491-497 (7 pages)
EGCG, the most biologically active compound in green tea, on trau- matic brain injury and its underlying mechanism. Our re- sults showed that EGCG sign ificantly inhibited TBI-in- duced edema formation and decreased vascular permeability. TBI-induced inflammation was reduced by EGCG treatment. Moreover, EGCG treatment significantly inhibited AQP4 and GFAP expression in injured brain tissue. As... Traumatic brain injury (TBI) is a major cause of mortality and long-term disability, which can decrease quality of life. In spite of numerous studies suggesting that Epigallocatechin-3- gallate (EGCG) has been used as a therapeutic agent for a broad range of disorders, the effect of EGCG on TBI remains unknown. In this study, a weight drop model was established to evaluate the therapeutic potential of EGCG on TBI. Rats were administered with 100 mg/kg EGCG or PBS intraperitoneally. At different... -
The Effect of Polyphenols Isolated from Cynanchi wilfordii Radix with Anti-inflammatory, Antioxidant, and Anti-bacterial Activity
SunyoungJeong, SunwooLee, WooJinChoi, UyDongSohn, WonyongKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.2 10 151-158 (8 pages)
involving vascular disorders, includ- ing diabetes mellitus, ischemia-induced diseases, and the progression of aging [2]. It is widely used as an effective functional food for management of fatigue, osteoporosis, and constipation, pa rticularly in menopausal disorders. Cynanchi wilfordii Radix , a plant belonging to the Asclepia- daceae family, is commonly used in Oriental medicine. It is a... a functional food effective for relieving fatigue, osteoporosis, and constipation, particularly in menopausal disorders. However, its anti-inflammatory and anti-microbial activities have not been explored in detail to date. The anti-inflammatory, antioxidant, and anti-bacterial properties of the Cynanchi wilfordii Radix extracts obtained with water, methanol, ethanol, and acetone were compared. All 4 polyphenol- containing extracts exhibited anti-inflammatory and antioxidant effects. The ethanol... -
Bisphenol A and 4-tert-Octylphenol Inhibit Cx46 Hemichannel Currents
SeunghoonOh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.1 11 73-79 (7 pages)
channel blockers. Curr Drug Targets. 2002;3:455-464. 22. Boger DL, Patterson JE, Guan X, Cravatt BF, Lerner RA, Gilula NB. Chemical requirements for inhibition of gap junction communication by the biologically active lipid oleamide. Proc Natl Acad Sci U S A. 1998;95:4810-4815. 23. Srinivas M, Hopperstad MG, Spray DC. Quinine blocks specific gap junction channel subtypes. Proc Natl Acad Sci U ... Connexins (Cx) are membrane proteins and monomers for forming gap junction (GJ) channels. Cx46 and Cx50 are also known to function as conductive hemichannels. As part of an ongoing effort to find GJ-specific blocker(s), endocrine disruptors were used to examine their effect on Cx46 hemichannels expressed in Xenopus oocytes. Voltage-dependent gating of Cx46 hemichannels was characterized by slowly activating outward currents and relatively fast inward tail currents. Bisphenol A (BPA, 10 nM)... -
Immunostimulatory Effects of b-glucan Purified from Paenibacillus polymyxa JB115 on Mouse Splenocytes
Ji-MiKim, Hong-GuJoo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.4 1 225-230 (6 pages)
(β-glu- can) on mouse splenocytes. β-glucan-treated cells had en- hanced viability, were protected against cytokine with- drawal-induced cell death, and were more responsive to IL-2. Natural, biologically active compounds are ideal for clinical purposes due to their low intrinsic toxicities [22,23]. Our data provide valuable information that can be used to broaden the use of β-glucan as a... We investigated the effects of Ղ-glucan purified from Paenibacillus polymyxa JB115 on the viability and proliferation of splenocytes. Splenocytes play a critical role in host immunity. MTT assays and trypan blue exclusion tests revealed that Ղ-glucan significantly promoted the viability and proliferation of splenocytes over a range of concentrations. However, there was no specific subset change. Ղ-glucan protected splenocytes from cytokine withdrawal-induced spontaneous cell...