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전체 선택해제
총 127건 검색
본문검색 결과만 보기
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Ser1778 of 53BP1 Plays a Role in DNA Double-strand Break Repairs
Jung-HeeLee, Hyang-MinCheong, Mi-YoungKang, Sang-YoungKim, YoonsungKang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.5 2 343-348 (6 pages)
is a versatile and sensitive method for measuring single- and double-strand DNA breaks. Thus, we ..PAGE:5 Ser1778 of 53BP1 Plays a Role in DNA Double-strand Break Repairs 347 compared the relationship between the phosphorylation pattern of 53BP1 and DNA repair . As is shown in Fig. 4, we determined that the NCS-induced DNA breaks in U2OS cells were almost completely repaired at 18 hours. DNA... important genome stability regulator, which protects cells against double-strand breaks. Following DNA damage, 53BP1 is rapidly recruited to sites of DNA breakage, along with other DNA damage response proteins, including Ճ-H2AX, MDC1, and BRCA1. The recruitment of 53BP1 requires a tandem Tudor fold which associates with methylated histones H3 and H4. It has already been determined that the majority of DNA damage response proteins are phosphorylated by ATM and/or ATR after DNA damage, and... -
High Power Electric Double Layer Capacitor(EDLC's)
M.Endo, T.Takeda, Y.j.Kim 한국탄소학회 Carbon Letters 12 Pages
한국탄소학회 Carbon Letters Vol.1 No.3&4 1 117-128 (12 pages)
short distance, such as atomic distance, between both at the contact interface of two different phases (e.g., solid electrode and liquid). This charge distribution layer is called the electric double layer. There are various explanations for this interfacial charge distribu- tion. Fig. 2 presents the behavior of electrolyte ion and the pore with and without electric field. EDLC is made from a... -
Numerical estimation of ion transport and electroosmotic flow around a pair of cylindrical electrodes in a microchannel using immersed boundary method
Fernandes. Dolfred Vijay, Kang. Sang-Mo, Suh. Yong-Kweon 대한기계학회 Journal of mechanical science and technology 11 Pages
대한기계학회 Journal of mechanical science and technology 2010, Vol.24 No.12 2467-2477 (11 pages)
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Pressure pain threshold and visual analogue scale changes in the high and low energy extracorporeal shock wave
You-Jin Yang, Seung-Joon Lee, Matthew Choi 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2014, 제 3권 제 2호 10 142-147 (6 pages)
double blinded study, so there can be some bias because the exam- iner knew who was in the low energy group or in the high en- ergy group. Also we did not collect the data of disease dura- tion so we could not prove that there is no significant differ- ence of disease duration between the low energy group and the high energy group. Conflict of Interest The authors declared no potential conflicts... Objective: This study aims to investigate high energy and low energy extracorporeal shockwave therapy (ESWT) and which one is more effective for shoulder pain. Design: Single blind randomized controlled trial. Methods: Fifty two subjects with upper trapezius (UT) trigger point (TrP) participated in this study. They were allocated to high energy (n=26) and low energy group (n=26). This study applies ESWT and investigates the changes of pressure pain threshold (PPT) and visual analogue scale... -
Stress and language recovery in individuals with aphasia
Brian Sharp, Paige Shaughnessy, Lee Berk, Noha Daher 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2013, 제 2권 제 2호 6 92-98 (7 pages)
at noon so as to control for diurnal variability. The participants were instructed to bring the sali- va sample the morning of their language pre-testing. Once received, the salivary samples were double checked for vol- ume, correct labeling and collection time. All samples were then placed in a 80 oC freezer in the Molecular Research Lab in the School of Allied Health Professions, Loma Linda... Objective: Constraint induced aphasia therapy (CIAT) is a more intensive form of language treatment for aphasia as compared to traditional treatments. This study examined whether there are differences in cortisol stress levels between the two methods of aphasia treatment as well as effects on language skills. Design: Randomized controlled trial. Methods: A total of 20 participants with expressive aphasia were randomly placed into one of the two treatment groups. The CIAT group received 10 days... -
Analysis of swine leukocyte antigen class I gene profiles and porcine endogenous retrovirus viremia level in a transgenic porcine herd inbred for xenotransplantation research
Daria Matczyń, ska, Daniel Sypniewski, Sabina Gałka, Dagna Sołtysik, Tomasz Loch, Ewa Nowak, Zdzisław Smorą, g, Ilona Bednarek1 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 3호 8 384-392 (9 pages)
additive effect of double transfection (GLA and FUT2 genes) has been observed, and it resulted in complete absence of the Gal epitope on the cell surface [25]. In addition, regulation of the complement system may influence positive on xenograft acceptance. One of the complement system blocking agents is factor CD59 (membrane inhibitor of reactive lysis) that prevents entry of the complement... Molecular characterization of swine leukocyte antigen (SLA) genes is important for elucidating the immune responses between swine-donor and human-recipient in xenotransplantation. Examination of associations between alleles of SLA class I genes, type of pig genetic modification, porcine endogenous retrovirus (PERV) viral titer, and PERV subtypes may shed light on the nature of xenograft acceptance or rejection and the safety of xenotransplantation. No significant difference in PERV gag RNA level... -
Prevalence, toxin gene profile, antibiotic resistance, and molecular characterization of Clostridium perfringens from diarrheic and non-diarrheic dogs in Korea
Jung-Whan Chon, Kun-Ho Seo, Dongryeoul Bae, Ji-Hee Park, Saeed Khan, Kidon Sung 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 3호 6 368-374 (7 pages)
under aerobic and anaerobic conditions on blood agar. Colonies showing double hemolysis and growing only under anaerobic conditions were regarded as presumptive C perfringens strains, and were selected and stored at oC. Polymerase chain reaction (PCR) amplification A colony subcultured on blood agar was removed and genomic DNA was extracted by applying the boiling method [4]. Table 1 shows... Clostridium perfringens causes diarrhea and other diseases in animals and humans. We investigated the prevalence, toxin gene profiles, and antibiotic resistance of C. perfringens isolated from diarrheic dogs (DD) and non-diarrheic dogs (ND) in two animal hospitals in Seoul, Korea. Fecal samples were collected from clinically DD (n = 49) and ND (n = 34). C. perfringens was isolated from 31 of 49 DD (63.3%) and 21 of 34 ND dogs (61.8%). All C. perfringens strains were positive for the ... -
Immunogenicity of recombinant Lactobacillus plantarum NC8 expressing goose parvovirus VP2 gene in BALB/c mice
Yu-Ying Liu, Wen-Tao Yang, Shao-Hua Shi, Ya-Jie Li, Liang Zhao, Chun-Wei Shi, Fang-Yu Zhou, Yan-Long Jiang, Jing-Tao Hu, Wei Gu, 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 2호 5 159-167 (9 pages)
the recombinant expression plasmid pSIP-409-VP2 Positive pGEMT-VP2 plasmids were double-digested with XbaI and KpnI, and, after recycling and purification, the target fragments were ligated with T4 DNA ligase overnight at 16 o C with the pSIP-409 plasmid. The ligated products were then transformed into E. coli DH5 competent cells [23]. After screening the transformants by restriction enzyme... Goose parvovirus (GPV) continues to be a threat to goose farms and has significant economic effects on the production of geese. Current commercially available vaccines only rarely prevent GPV infection. In our study, Lactobacillus (L.) plantarum NC8 was selected as a vector to express the VP2 gene of GPV, and recombinant L. plantarum pSIP409-VP2/NC8 was successfully constructed. The molecular weight of the expressed recombinant protein was approximately 70 kDa. Mice were immunized with a 2 × 10... -
Retrospective study of the clinical effects of acupuncture on cervical neurological diseases in dogs
Ching Ming Liu, Fang Chia Chang, Chung Tien Lin 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 3호 10 337-345 (9 pages)
with ..PAGE:3 Acupuncture treatment of dogs with cervical spinal diseases 339 www.vetsci.org Table 2. The ingredients and actions of Double P II and Cervical Formula [20] Chinese herbs Ingredients Actions Double P II Angelica Dang Gui Break down stasis, Relieve pain Myrrh Mo Yao Break down stasis, Relieve pain Olibanum Ru Xiang Break down stasis, Relieve pain Strychnos Ma Qian Zi Move Qi, Relieve... This study was conducted to evaluate new acupuncture protocols for the clinical treatment of cervical spinal cord diseases in 19 dogs. Three treatment options containing Jing-jiaji (cervical jiaji) were developed to treat neck pain, hemiparesis, and tetraparesis depending on the severity. The interval between the neurological disease onset and treatment (duration of signs), time to improvement after treatment, and recovery time were compared in dogs by body weight,...