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Synthesis and Docking Studies of New 1,4-Dihydropyridines Containing 4-(5)-Chloro-2-ethyl-5-(4)-Imidazolyl Substituent as Novel Calcium Channel Agonist
Davood. Asghar, Nematollahi. Ali Reza, Iman. Maryam, Shafiee. Abbas 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 7 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2009, Vol.32 No.4 481-487 (7 pages)
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Oxidative Aromatization of Hantzsch 1,4-Dihydropyridines by SiO2/P2O5-SeO2 under Mild and Heterogeneous Conditions
Paul. Satya, Sharma. Shivani, Gupta. Monika, Choudhary. Deepak, Gupta. Rajive 대한화학회 Bulletin of the Korean Chemical Society 3 Pages
대한화학회 Bulletin of the Korean Chemical Society 2007, Vol.28 No.2 336-338 (3 pages)
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CuI Nanoparticles as New, Efficient and Reusable Catalyst for the One-pot Synthesis of 1,4-Dihydropyridines
Safaei-Ghomi. Javad, Ziarati. Abolfazl, Teymuri. Raheleh 대한화학회 Bulletin of the Korean Chemical Society 4 Pages
대한화학회 Bulletin of the Korean Chemical Society 2012, Vol.33 No.8 2679-2682 (4 pages)
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Polymer Support Immobilized Acidic Ionic Liquid: Preparation and Its Application as Catalyst in the Synthesis of Hantzsch 1,4-Dihydropyridines
Jahanbin. Bentolhoda, Davoodnia. Abolghasem, Behmadi. Hossein, Tavakoli-Hoseini. Niloofar 대한화학회 Bulletin of the Korean Chemical Society 5 Pages
대한화학회 Bulletin of the Korean Chemical Society 2012, Vol.33 No.7 2140-2144 (5 pages)
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An Expeditious Oxidative Aromatization of Hantzsch 1,4-Dihydropyridines to Pyridines Using Cetyltrimethylammonium Peroxodisulfate: A Phase Transferring Oxidant
Kumar. Parvin, Kumar. Ashwani 대한화학회 Bulletin of the Korean Chemical Society 5 Pages
대한화학회 Bulletin of the Korean Chemical Society 2010, Vol.31 No.8 2299-2303 (5 pages)
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Oxidation of Hantzsch 1,4-Dihydropyridines Using Supported Nitric Acid on Silica Gel and Poly Vinyl Pyrrolidone (PVP) under Mild and Heterogeneous Conditions
Ghorbani-Choghamarani. Arash, Nikoorazm. Mohsen, Goudarziafshar. Hamid, Shiri. Lotfi, Chenani. Zahra 대한화학회 Bulletin of the Korean Chemical Society 3 Pages
대한화학회 Bulletin of the Korean Chemical Society 2009, Vol.30 No.4 972-974 (3 pages)
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An Efficient Oxidation of 1,4-Dihydropyridines to Pyridines Using Silver Carbonate on Silica Gel and Celite
Momeni. Ahmad Reza, Sameh. Tayebeh, Golmohammadi. Hosein, Naghash. Hamid Javaherian, Aliyan. Hamid, Massah. Ahmad Reza, Solati. Shirin 대한화학회 Bulletin of the Korean Chemical Society 2 Pages
대한화학회 Bulletin of the Korean Chemical Society 2006, Vol.27 No.3 355-356 (2 pages)
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Efficient Introduction of Aryl Acetylenes to Quinolinium and Pyridinium Salts: Synthesis of 1-Acyl-1,2-dihydroquinolines and 1-Acyl-1,2-dihydropyridines
Lee. Ka-Young, Lee. Mi-Jung, Kim. Jae-Nyoung 대한화학회 Bulletin of the Korean Chemical Society 3 Pages
대한화학회 Bulletin of the Korean Chemical Society 2005, Vol.26 No.4 665-667 (3 pages)
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Chronic Ca2+ influx through voltage-dependent Ca2+ channels enhance delayed rectifier K+ currents via activating Src family tyrosine kinase in rat hippocampal neurons
Yoon-SilYang, Sang-ChanJeon, Dong-KwanKim, Su-YongEun, Sung-CherlJung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.2 14 259-265 (7 pages)
Excessive influx and the subsequent rapid cytosolic elevation of Ca2+ in neurons is the major cause to induce hyperexcitability and irreversible cell damage although it is an essential ion for cellular signalings. Therefore, most neurons exhibit several cellular mechanisms to homeostatically regulate cytosolic Ca2+ level in normal as well as pathological conditions. Delayed rectifier K+ channels (IDR channels) play a role to suppress membrane excitability by inducing K+ outflow in various... -
Inhibitory Effects of Ginsenoside-Rb2 on Nicotinic Stimulation-Evoked Catecholamine Secretion
Hyo-JeongLim, Hyun-YoungLee, Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.5 12 431-439 (9 pages)
The aim of the present study was to investigate whether ginsenoside-Rb2 (Rb2) can affect the secretion of catecholamines (CA) in the perfused model of the rat adrenal medulla. Rb2 (3∼30 μM), perfused into an adrenal vein for 90 min, inhibited ACh (5.32 mM)-evoked CA secretory response in a dose- and time-dependent fashion. Rb2 (10 μM) also time-dependently inhibited the CA secretion evoked by DMPP (100 μM, a selective neuronal nicotinic receptor agonist) and high K+ (56 mM, a direct membrane... -
Polyphenols of Rubus coreanum Inhibit Catecholamine Secretion from the Perfused Adrenal Medulla of SHRs
Byung-SikYu, Duck-MiNa, Mi-YoungKang, Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.6 17 517-526 (10 pages)
The present study was attempted to investigate whether polyphenolic compounds isolated from wine, which is brewed from Rubus coreanum Miquel (PCRC), may affect the release of catecholamines (CA) from the isolated perfused adrenal medulla of the spontaneously hypertensive rats (SHRs), and to establish its mechanism of action. PCRC (20∼180Ռg/ml) perfused into an adrenal vein for 90 min relatively dose-dependently inhibited the CA secretory responses to ACh (5.32 mM), high K＋ (56 mM), DMPP... -
Naltrexone Inhibits Catecholamine Secretion Evoked by Nicotinic Receptor Stimulation in the Perfused Rat Adrenal Medulla
Byung-SikYu, Seon-YoungMin, Yoo-SeokSeo, Cheol-HeeChoi, Eun-HwaLee, Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.4 6 223-230 (8 pages)
The purpose of the present study was to examine the effect of naltrexone, an opioid antagonist, on secretion of catecholamines (CA) evoked by cholinergic nicotinic stimulation and membrane-depolarization from the isolated perfused rat adrenal gland and to establish the mechanism of its action. Naltrexone (3⁓106 M) perfused into an adrenal vein for 60 min produced time-dependent inhibition in CA secretory responses evoked by ACh (5.32⁓103 M), high K... -
Effect of Amrinone, a Selective Inhibitor of Phosphodiesterase III, on PMNs-induced
ByungKwonOh, HyoungKiKim, SooRanChoi, JinHoSong, EonSubPark, Byung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.1 7 43-50 (8 pages)
Ischemia followed by reperfusion in the presence of polymorphonuclear leukocytes (PMNs) results in a marked cardiac contractile dysfunction. Amrinone, a specific inhibitor of phosphodiesterase 3, has an antioxidant activity against PMNs. Therefore, we hypothesized that amrinone could attenuate PMNs-induced cardiac dysfunction by suppression of reactive oxygen species (ROS) produced fby PMNs. In the present study, we examined the effects of amrinone on isolated ischemic (20 min) and reperfused... -
Influence of Tacrine on Catecholamine Secretion in the Perfused Rat Adrenal Gland
Seok-JeongJang, Won-HoYang, Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.4 6 207-214 (8 pages)
The present study was designed to clarify whether tacrine affects the release of catecholamines (CA) from the isolated perfused model of rat adrenal gland or not and to elucidate the mechanism of its action. Tacrine (3⁓105∼3⁓104 M) perfused into an adrenal vein for 60 min inhibited CA secretory responses evoked by ACh (5.32⁓103 M), DMPP (a selective neuronal nicotinic agonist, 104 M for 2 min) and McN-A-343 (a selective muscarinic M1-agonist,... -
Nimodipine as a Potential Pharmacological Tool for Characterizing R-Type Calcium Currents
SeogBaeOh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.6 8 511-519 (9 pages)
Nimopidine, one of dihydropyridine derivatives, has been widely used to pharmacologically identify L-type Ca currents. In this study, it was tested if nimodipine is a selective blocker for L-type Ca currents in sensory neurons and heterologous system. In mouse dorsal root ganglion neurons (DRG), low concentrations of nimodipine (＜10μM), mainly targeting L-type Ca currents, blocked high-voltage-activated calcium channel currents by ∼38%. Interestingly, high concentrations of nimodipine... -
N-Type Calcium Channels
KeithS.Elmslie 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.6 12 525-530 (6 pages)
The early studies of cardiac and smooth muscle cells provided evidence for two different calcium channels, the L-type (also called high-voltage activated [HVA]) and the T-type (low-voltage activated [LVA]). These calcium channels provided calcium for muscle contractions and pace-making activities. As might be expected, the number of different calcium channels increased when researchers studied neurons and the identification of the neuronal calcium channel has proven to be much more difficult...
