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Acute Toxicity Study on Fermented Ginkgo Epicarp in ICR Mice
Ha Young Kim, Hong Kook Kim, Byeong Soo Kim 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 77 225-226 (2 pages)
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Acute Toxicity Study of Recombinant Granulocyte-Macrophage Colony Stimulating Factor (LBD-005) in ICR mice
Kim. Hyoung-Chin, Song. Si-Whan, Cha. Shin-Woo, Shin. Chun-Chul, Ha. Chang-Su, Han. Sang-Seop 한국응용약물학회 The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmaco 5 Pages
한국응용약물학회 The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmaco 1993, Vol.1 No.2 270-274 (5 pages)
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Acute Toxicity Study of Recombinant Human Interferon ${alpha}A$ (LBD-007) in ICR Mice
Kim. Hyoung-Chin, Song. Si-Whan, Cha. Shin-Woo, Shin. Chun-Chul, Ha. Chang-Su, Han. Sang-Seop 한국응용약물학회 The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmaco 4 Pages
한국응용약물학회 The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmaco 1993, Vol.1 No.2 266-269 (4 pages)
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A PRELIMINARY STUDY ON THE ACUTE TOXICITY OF TARTRAZINE IN RABBIT AND GUINEA PIG
유태종, Yu. Tai-Jong 한국응용생명화학회 한국농화학회지 4 Pages
한국응용생명화학회 한국농화학회지 1970, Vol.13 No.3 257-260 (4 pages)
식용색소(食用色素) Tartrazine을 토끼의 경우 $7.5{sim}50mg/kg$, 몰모트의 경우 $1,000{sim}2,000mg/$수(首)를 경구(經口) 또는 복막주사(腹膜注射), 정맥주사(靜脈注射)로 투여(投與)하여 그 동물(動物)에 있어서의 색소(色素)의 독성(毒性)을 관찰조사(觀察調査)하였다. 혈청(血淸)은 화학분석(化學分析)하였고 각各 장기(臟器)는 현미경적(的) 관찰(觀察)을 통(通)하여 조사(調査)하였다. 그 결과(結果) 사용(使用)한 양(量)의 색소(色素)로서 대부분(大部分)의 장기(臟器)가 충혈(充血) 또는 출혈(出血)되였고 특(特)히... -
Acute and Sub-chronic Oral Toxicity Study of Ammonium Persulfate in Spraque-Dawley Rats
Kim. Yong-Soon, Baek. Min-Won, Sung. Jae-Hyuck, Ryu. Hyun-Youl, Kim. Jin-Sik, Cho. Hyun-Sun, Choi. Byung-Gil, Song. Min-Sub, Song. Moon- 한국독성학회 Toxicological research 8 Pages
한국독성학회 Toxicological research 2009, Vol.25 No.3 132-139 (8 pages)
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Chemoradiation Related Acute Morbidity in Carcinoma Cervix and Correlation with Hematologic Toxicity: A South Indian Prospective Study
Kumaran. Aswathy, Guruvare. Shyamala, Sharan. Krishna, Rai. Lavanya, Hebbar. Shripad 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 4 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2014, Vol.15 No.11 4483-4486 (4 pages)
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Acute Toxicity and General Pharmacological Action of QGC EXT
JongMiLee, WiJoonIm, YoonJinNam, KyungHoonOh, JaeChunLim, WanKyunnWhang, UyDongSohn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.1 8 49-57 (9 pages)
It has been shown that QGC isolated and purified from Rumecis folium found protective effects of gastritis and esophagitis which EXT is an ethanol extract of it. We examined acute toxicity and the general pharmacological action of QGC EXT to search for any side effects of it in rats, mice, guinea pigs, and cats. In a single dose toxicity study, QGC EXT didn't show toxicological effects in rats and mice, and the LD50 was over 5 g/kg in both animals, and there were also no changes in weight, feed... -
A Single Oral Dose Toxicity Study of Bamboo Leaf Water Extract in Sprague-Dawley Rats
Shin. Dong-Ho, Jang. Pan-Gu, Oh. Ki-Seok, Kim. Jae-Ha, Chung. Hee-Jong, Kim. Jong-Choon 한국응용약물학회 The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmaco 4 Pages
한국응용약물학회 The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmaco 2003, Vol.11 No.3 200-203 (4 pages)
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A Single Oral Dose Toxicity Study of Plant Sterol Ester in Sprague-Dawley Rats
Kim. Jong-Choon, Kim. Kab-Sig, Chung. Dae-Won, Chung. Moon-Koo 한국응용약물학회 The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmaco 4 Pages
한국응용약물학회 The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmaco 2000, Vol.8 No.2 167-170 (4 pages)
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Acute Hematotoxicity induced by diazinon in SD rats
Su Hyeon Kim, Sang Hee Jeong, Sang Jung Park, Sang In Lee, Chae Ryeong Yi, Si Wan Han, Jae Eun Kim 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 330 388-389 (2 pages)
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A 2-week Dose Range Finding Study of KMRC01, Salmonella flagellin-derived TLR 5 agonist, administered by intramuscular injection in Cynomolgus Monkeys
Hong Soo Lee, Son Il Pak, Doo Wan Cho, Woo Jong Lee, Chi Min Choi, Dong Hun Jung, Su Cheol Han 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 180 309-309 (1 pages)
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Toxicity of crude and detoxified Tityus serrulatus venom in anti-venom-producing sheep
Marina G. Ferreira, Clara G. Duarte, Maira S. Oliveira, Karen L. P. Castro, Ma?lson S. Teixeira, L?lian P. G. Reis, Jos? A. Zamb 대한수의학회 Journal of Veterinary Science 11 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 4호 5 467-477 (11 pages)
the immunogens used. This study was conducted to evaluate the toxic and immunogenic activities of crude and detoxified Tityus serrulatus (Ts) venom in sheep during the production of anti-scorpionic anti-venom. Sheep were categorized into three groups: G1, control, immunized with buffer only; G2, immunized with crude Ts venom; and G3, immunized with glutaraldehyde-detoxified Ts venom. All animals were subjected to clinical exams and supplementary tests. G2 sheep showed mild clinical changes, but... -
In vitro toxicity of melamine against Tetrahymena pyriformis cells
Zhengfang Wang, Liben Chen, Rashad Al-Kasir, Bo Han* 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2011, 제 12권 제 1호 5 27-34 (8 pages)
This study assessed the toxicity of melamine against the unicellular eukaryotic system of Tetrahymena (T.) pyriformis exposed to 0, 0.05, 0.25, 0.5, 2.5, and 5 mg/mL of melamine. Cell growth curves of different cultures, the half maximum inhibition concentration (IC50) value of melamine, and morphological changes in cells were obtained via optical and transmission electron microscopic observation. The effects of eleven melamine concentrations, 0.25, 0.5, 1, 1.5, 2, 2.5, 3, 3.5, 4, 4.5 and 5... -
Histopathological retrospective study of canine renal disease in Korea, 2003∼2008
Ji-Young Yhee, Chi-Ho Yu, Jong-Hyuk Kim, Keum-Soon Im, Seung-Ki Chon, Jung-Hyang Sur* 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2010, 제 11권 제 4호 1 277-283 (7 pages)
in this study. Tissue histopathology was performed using light microscopy with hematoxylin and eosin stains. Masson's trichrome, Congo Red, and Warthin starry silver staining were applied in several individual cases. Glomerular diseases (22.9%), tubulointerstitial diseases (8.6%), neoplastic diseases (8.6%), conditions secondary to urinary obstruction (24.3%), and other diseases (35.7%) were identified. Glomerulonephritis (GN) cases were classified as acute proliferative GN (5.7%), membranous GN... -
Pathological features of bone marrow transplantation-related toxicity in a mouse
Yong-Hoon Kim, Chang-Su Ha, Hyun-Sook Lee, Sun-Hwa Lim, Kyoung-Sik Moon, Moon-Koo Chung, Hwa-Young Son* 대한수의학회 Journal of Veterinary Science 3 Pages
대한수의학회 Journal of Veterinary Science 2009, 제 10권 제 4호 15 361-363 (3 pages)
In this case report, we present a mock-transduced bone marrow (BM) transplantation in a mouse, which was found moribund and autopsied to evaluate pathogenesis. Macroscopically, red discoloration of systemic organs was observed. Hematological values revealed a decrease in white blood cells, red blood cells, hematocrit, hemoglobin, and platelets, but an increase in reticulocytes. In BM cytology, hematopoietic cell lines were severely depleted. Histopathologically, hemorrhage in the cerebellar... -
Comparative study on the aflatoxin B1 degradation ability of rumen fluid from Holstein steers and Korean native goats
Santi Devi Upadhaya, Ha Guyn Sung, Chan Hee Lee, Se Young Lee, Sun Woo Kim, Kyung Jin Cho, Jong K. Ha* 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2009, 제 10권 제 1호 5 29-34 (6 pages)
The aflatoxin B1 degrading abilities of two different ruminants were compared in this study. One set of experiments evaluated the aflatoxin B1 degradation ability of different rumen fluid donors (steers vs. goats) as well as the rumen fluid filtration method (cheese cloth filtered vs. 0.45 Ռm Millipore) in a 2 × 2 factorial arrangement. Additional studies examined aflatoxin B1 degradation by collecting rumen fluid at different times (0, 3, 6, 9 and 12 h) after feeding. Cannulated...


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