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Screening and Histopathological Characterization of Korean Carrot Lines for Resistance to the Root-Knot Nematode Meloidogyne incognita
한국식물병리학회 The Plant Pathology Journal 7 Pages
한국식물병리학회 The Plant Pathology Journal 2014, 30권 1호 9 75-81 (7 pages)
In total, 170 carrot lines developed in Korea were screened for resistance to Meloidogyne incognita race 1 to select parental genetic resources useful for the development of nematode-resistant carrot cultivars. Using the gall index (GI), gall formation was examined on carrot roots inoculated with approximately 1,000 second-stage juveniles of the nematode 7 weeks after inoculation. Sixty-one carrot lines were resistant (GI ≤ 1.0), while the other 109 were susceptible (GI > 1.0) with... -
Quantitative real-time polymerase chain reaction for detecting Mycoplasma hyosynoviae and Mycoplasma hyorhinis in pen-based oral, tonsillar, and nasal fluids
João Carlos Gomes Neto, Leslie Bower, Barbara Z. Erickson, Chong Wang, Matthew Raymond, Erin L. Strait 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 2호 9 195-201 (7 pages)
Mycoplasma (M.) hyorhinis and M. hyosynoviae are pathogens known to cause disease in pigs post-weaning. Due to their fastidious nature, there is increased need for culture-independent diagnostic platforms to detect these microorganisms. Therefore, this study was performed to develop and optimize quantitative real-time PCR (qPCR) assays to rapidly detect M. hyorhinis and M. hyosynoviae in pen-based oral fluids as well as nasal and tonsillar fluids as proxies for samples used in swine herd... -
Influence of endotoxin induced fever on the pharmacokinetics of intramuscularly administered cefepime in rabbits
Ayman Goudah, Samar M. Mouneir, Jae-Han Shim, A. M. Abd El-Aty 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 2호 10 151-155 (5 pages)
This study examined the effect of experimentally induced fever on the pharmacokinetics of cefepime (75 mg/kg BW) administered intramuscularly to six rabbits. The study was carried out in two consecutive phases separated by a two-week washout period. An infection was induced by an intravenous inoculation of 5 × 108 colony-forming units of Escherichia coli 24 h before the pharmacokinetic investigation. A quantitative microbiological assay was employed to measure the plasma cefepime concentrations... -
Antidepressant drug paroxetine blocks the open pore of Kv3.1 potassium channel
HyangMiLee, OkHeeChai, SangJuneHahn, BokHeeChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.1 8 71-80 (10 pages)
a Hill coefficient of 1.43, and also accelerated the decay of Kv3.1 current. The paroxetine-induced inhibition of Kv3.1 channels was voltage-dependent even when the channels were fully open. The binding (k+1) and unbinding (k–1) rate constants for the paroxetine effect were 4.5 µM–1s–1 and 35.8 s–1, respectively, yielding a calculated KD value of 7.9 µM. The analyses of Kv3.1 tail current indicated that paroxetine did not affect ion selectivity and slowed its... -
Blockade of Kv1.5 channels by the antidepressant drug sertraline
HyangMiLee, SangJuneHahn, BokHeeChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.2 8 193-200 (8 pages)
Hill coefficient of 0.71 μM and 1.29, respectively. Sertraline accelerated the decay rate of inactivation of Kv1.5 currents without modifying the kinetics of current activation. The inhibition increased steeply between –20 and 0 mV, which corresponded with the voltage range for channel opening. In the voltage range positive to +10 mV, inhibition displayed a weak voltage dependence, consistent with an electrical distance δ of 0.16. Sertraline slowed the deactivation time course, resulting... -
Blockade of Kv1.5 by paroxetine, an antidepressant drug
HyangMiLee, SangJuneHahn, BokHeeChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.1 10 75-82 (8 pages)
and a Hill coefficient of 4.11 µM and 0.98, respectively. Paroxetine accelerated the decay rate of inactivation of Kv1.5 currents without modifying the kinetics of current activation. The inhibition increased steeply between –30 and 0 mV, which corresponded with the voltage range for channel opening. In the voltage range positive to 0 mV, inhibition displayed a weak voltage dependence, consistent with an electrical distance d of 0.32. The binding (k+1) and unbinding (k–1) rate... -
Aortic Remodelling in Chronic Nicotine-Administered Rat
SatirahZainalabidin, SitiBalkisBudin, AnRamalingam, YiChengLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.5 9 411-418 (8 pages)
(equivalent to light smoker) on aortic reactivity, oxidative stress markers and histomorphological changes. Twelve age-matched male Sprague-Dawley rats were randomly divided into two groups, i.e.: normal saline as control or 0.6 mg/kg nicotine for 28 days (i.p., n=6 per group). On day-29, the rats were sacrificed and the thoracic aorta was dissected immediately for further studies. Mean arterial pressure (MAP) and pulse pressure (PP) of nicotine-treated vs. control were significantly increased... -
Dietary Ascorbate Supplementation Reduces Oxidative Tissue Damage and Expression of iNOS in the Kidney of Streptozotocin Induced Diabetic Rats
MyungSeoupChoi, YoonYoungJang, WooSeungLee, JinHoSong, YongKyooShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.1 8 39-45 (7 pages)
Reactive oxygen species (ROS) have been suggested to be contributory factors in complications of diabetes mellitus. In the present study, we investigated the generation of superoxide, the lipid peroxide level measured as thiobarbituric acid reactive substances, the vasorelaxation of isolated thoracic aorta and the iNOS expression in kidney of streptozotocin induced diabetic rats. Sprague Dawley rats were divided into four groups: control, ascorbate (400 mg/kg rat weight daily in drinking water),... -
Activation of ATP-sensitive Potassium Channels by the Predominant Metabolite of Isoflurane in Rabbit Ventricular Myocytes
JinHan, NariKim, EuiyongKim, SungjuKim, KangheeCho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.2 7 165-175 (11 pages)
in a concentration-dependent fashion. The concentration of TFA for half-maximal activation and the Hill coefficient were 0.03 mM and 1.2, respectively. TFA did not affect the single channel conductance of KATP channels. Analysis of open and closed time distributions showed that TFA increased burst duration and decreased the interburst interval without changes in open and closed time distributions shorter than 5 ms. TFA diminished ATP sensitivity of KATP channels in a concentration-response... -
Virulence Structure of Blumeria graminis f. sp. avenae Populations in Poland across 2014-2015
Magdalena Cieplak, Katarzyna Terlecka, Tomasz Ociepa, Beata Zimowska, Sylwia Oko? 한국식물병리학회 The Plant Pathology Journal 9 Pages
한국식물병리학회 The Plant Pathology Journal 2021, 37권 2호 3 115-123 (9 pages)
of oat powdery mildew (Blumeria grami- nis f. sp. avenae, Bga) populations in Poland collected in 2014 and 2015. Powdery mildew isolates were collected from 18 locations in Poland. In total, nine lines and cultivars of oat, with different mildew resistance genes, were used to assess virulence of 180 isolates. The results showed that a significant proportion of the Bga isolates found in Poland were virulent to differentials with Pm1, Pm3, Pm6, and Pm3 + Pm8 genes. In contrast Pm4, Pm5, Pm2, and... -
Triazole Fungicides Sensitivity of Sclerotinia homoeocarpa in Korean Golf Courses
한국식물병리학회 The Plant Pathology Journal 8 Pages
한국식물병리학회 The Plant Pathology Journal 2017, 33권 6호 7 589-596 (8 pages)
that of the control strains. Two isolates of S. homoeocarpa S0–41 and Sh14-2-1 showed sensitivity toward all the fungicides used, while two other isolates Sh7-5-1 and Sh2-1-1 showed resistance to all fungicides. Each isolate showed similar resistance to the three types of triazole fungicides, whereby cross-resistance of isolates was confirmed in the present study; all three triazole fungicide combinations displayed significant correlation coefficients equivalent to or greater than 0.8. -
캐나다 이주 한국인들의 전반적인 여가 의미 측정도구 개발
한국여가문화학회 여가학연구 2018, vol.16 no.1 1 1-28 (28 pages)
일반인들이 여가활동으로부터 경험하는 여가 의미들의 문화간적인 연구는 계속 성장하고 있다. 여가학 학문 안에서 여가의 의미에 초점을 둔 연구는 스트레스 해소와 인간 발달에 중요한 함의를 준다. 본 연구는 캐나다 이주 한국인들을 대 상으로 한 전반적인 여가 의미 (GLMS) 측정도구 개발을 다루고 있다. 전반적인 여가 의미는 일반인들이 일생의 삶을 통하여 내재화되어지고 일반화 되어진 여가 의미들의 총체 및 집적체로 정의될 수 있다. 본 연구는 탐색적 요인분석 통계적 방법을 이용하여 6개의 전반적인 여가 의미 요인구조를... -
유한차분법과 유한체적법을 이용한 1차원과 2차원 개수로 흐름해석
김만식, 이진희, 정찬, 박노혁 한국습지학회 한국습지학회지 13 Pages
한국습지학회 한국습지학회지 2008, Vol.10 No.2 5 67-79 (13 pages)
하천에서의 부정류 해석을 위해서 1차원 유한차분법(FDM)인 Abbott-Ionescu scheme과 2차원 유한체적법(FVM)인 근사의 Riemann solver(Osher scheme)에 대하여 살펴보았다. 두 모형은 직선 하도, 약간 굽어진 사행하도 및 사행하도에서의 흐름 문제들에 적용되었으며 결과의 비교는 균일한 직사각형 수로에 대하여 이루어졌다. 하천의 복잡한 형상의 표현하기 위해서는 이를 고려할 수 있는 유한체적법을 이용하였다. 유한차분법과 유한체적법 결과는 수위 및 유량 수문곡선에 대하여 매우 만족스러운 것으로 나타났다. 균일한 직선하도에... -
동기면담이 심부전 환자의 질병 관련 지식, 우울, 자가간호 및 삶의 질에 미치는 효과
김성민, 이해정 한국노인간호학회 노인간호학회지 12 Pages
한국노인간호학회 노인간호학회지 2013, 제 15권 제 2호 7 143-154 (12 pages)
심부전은 만성적으로 지속되는 노인인구에서 흔하게 발병 하는 질환으로, 치료기술의 발달에도 불구하고 그 유병률과 사망률이 높고(van Jaarsveld et al., 2006), 잦은 입원, 낮은 삶의 질, 다양한 동반질환, 복잡한 치료방법 등을 특징으로 하 는 임상 증후군이다(Heart Failure Society of America, 2010). 심부전의 주요 증상인 피로와 호흡곤란은 환자들의 일 상생활 기능을 제한하며 잦은 입원과 사망의 주요 원인이 되 며(Schnell-Hoehn, Naimark, & Tate, 2009), 환자들은 높 은 수준의 우울과 낮은 삶의 질을 경험한다(Gottlieb... -
구조물 밀집지역 범람수치모의를 위한 상당저항계수 산정 수치실험
김형석, 최준우, 고광오, 윤성범, Kim. Hyeong-Seok, Choi. Jun-Woo, Ko. Kwang-Oh, Yoon. Sung-Bum 한국해안해양공학회 한국해안·해양공학회논문집 8 Pages
한국해안해양공학회 한국해안·해양공학회논문집 2008, Vol.20 No.6 532-539 (8 pages)
권 등(2008)은 수면보다 높은 사각기둥 저항체를 등간격으로 배치하고 항력계수가 일정한 값을 갖는 흐름조건$(Re>10^4)$에서 수리실험을 수행하여 바닥마찰과 형상저항에 의한 흐름저항을 나타내는 상당저항계수로서의 Manning계수 값을 산정하였다. 그리고 힘의 평형방정식으로부터 유도된 이론식에 실험결과를 사용하여 얻어진 경험적 항력상호작용계수를 도입하여 얻은 상당저항계수 식을 제안하였다. 본 연구에서는 이 수리실험을 3차원 전산유체해석 프로그램인 FLOW-3D를 사용하여 수치모의하고 그 결과를 실험결과 및... -
통계적 분석을 이용한 터널 환기시스템 적정설계변수의 산정 및 적용에 관한 연구
이보영, 유용호, 김진 한국암반공학회 터널과 지하공간: 한국암반공학회지 8 Pages
한국암반공학회 터널과 지하공간: 한국암반공학회지 2004, Vol.14 No.5 373-380 (8 pages)
본 연구에서는 도로터널 환기시설 설계기준에 의한 소요환기량 산정 시 오염물질의 기준배출량을 환경부 고시기준에 대해 산정하여 차종별, 속도별로 산정된 기준배출량을 모델터널에 적용하여 시뮬레이션 한 결과 기존의 배출량 기준 적용에 대해 소요환기량은 약 49%로 감소되었다. 또한 터널 내 유동손실로서 작용하는 변수 중 터널마찰계수와 입구저항계수 및 등가저항면적을 통계적 분석기법을 이용하여 이들 계수 중 터널의 환기량 산정에 가장 민감하게 영향을 미치는 인자가 마찰계수이며 시뮬레이션을 통해 실제 적용 가능한... -
Pharmacokinetics of tilmicosin in healthy pigs and in pigs experimentally infected with Haemophilus parasuis
Ling Zhang, Li Zhao, Yonghong Liu, Junfeng Liu, Xianqiang Li 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 4호 2 431-437 (7 pages)
A comparative in vivo pharmacokinetic (PK) study of tilmicosin (TIL) was conducted in 6 crossbred healthy pigs and 6 crossbred pigs infected with Haemophilus (H.) parasuis following oral administration of a single 40 mg/kg dose. The infected model was established by intranasal inoculation and confirmed by clinical signs, blood biochemistry, and microscopic examinations. Plasma TIL concentrations were determined by a validated high-performance liquid chromatography method with ultraviolet... -
Transcranial Doppler ultrasound analysis of resistive index in rostral and caudal cerebral arteries in dogs
Minho Seo, Hojung Choi, Kichang Lee, Mincheol Choi, Junghee Yoon 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2005, 제 6권 제 1호 9 61-66 (6 pages)
Transcranial Doppler (TCD) was carried out to determine the resistive index (RI) values of normal canine cerebral arteries and its reproducibility and to evaluate the change of cerebral vascular resistance following diuretics administration. RI values of rostral cerebral artery (RCA) were compared between fontanelle window and temporal window. Normal ranges and reproducibility of the RI values were examined in the rostal cerebral artery (RCA) and caudal cerebral artery (CCA). And after...
