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Temperature is a key factor for inflammasome activation
Sang hoon Seo, Geun Shik Lee 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 289 350-351 (2 pages)
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Failurein neuroprotection of remote limb ischemic postconditioning (RIPoC) in the hippocampus of a gerbil model of transient cerebral ischemia
Hyun Jin Tae, Byung Yong Park, In Shik Kim, Dong choon Ahn, Ji Hyeon Ahn, Joon Ha Park, Jeong Hwi Cho, Bich Na Shin, Tae Kyeong Lee, Jae 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 288 350-350 (1 pages)
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Molecular characterization of the feline T-cell receptor γ alternate reading frame protein (TARP) ortholog
Alexander Th. A. Weiss*, Marie-Charlotte von Deetzen, Werner Hecht, Manfred Reinacher, Achim D. Gruber 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2012, 제 13권 제 4호 3 345-353 (9 pages)
T-cell receptor γ alternate reading frame protein (TARP) is expressed by human prostate epithelial, prostate cancer, and mammary cancer cells, but is not found in normal mammary tissue. To date, this protein has only been described in humans. Additionally, no animal model has been established to investigate the potential merits of TARP as tumor marker or a target for adoptive tumor immunotherapy. In this study conducted to characterize feline T-cell receptor γ sequences, constructs very... -
Changes of biomarkers with oral exposure to benzo(a)pyrene, phenanthrene and pyrene in rats
Hwan Goo Kang, Sang Hee Jeong*, Myung Haing Cho, Joon Hyoung Cho 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 4호 8 361-368 (8 pages)
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants present in air and food. Among PAHs, benzo(a)pyrene(BaP), phenanthrene (PH) and pyrene (PY) are considered to be important for their toxicity or abundance. To investigate the changes of biomarkers after PAH exposure, rats were treated with BaP (150 ■g/kg) alone or with PH (4,300 ■g/kg) and PY (2,700 ■g/kg) (BPP group) by oral gavage once per day for 30 days. 7-ethoxyresorufin-O-deethylase activity in liver... -
Improvement Characteristics of Bio-active Materials Coated Fabric on Rat Muscular Mitochondria
DongheeLee, Young-WonKim, Jung-HaKim, MisukYang, HyemiBae, InjaLim, HyoweonBang, Kyung-ChanGo, Gwang-WungYang, Yong-HwanRho, Hyo-SukPark, E 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.3 14 283-289 (7 pages)
to decrease in control group, but the expression was down-regulated then subsequently increased with the use of the BMCF in a dose-dependent manner. Caspase 3 increased and subsequently decreased in a dose-dependent manner. These results suggest that the BMCF invigorates mitophagy and improves mitochondrial oxidative respiration in skeletal muscle, and in early stage of apoptosis induced by the BMCF is not related to extrinsic death-receptor mediated but mitochondria-mediated signaling pathway. -
Microarray Analysis of Gene Expression Profiles in Response to Treatment with Melatonin in Lipopolysaccharide Activated RAW 264.7 Cells
JuYeonBan, BumSikKim, SooCheolKim, DongHwanKim, Joo-HoChung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.1 4 23-30 (8 pages)
of 1073 genes and the down-regulation of 1144 genes when compared to the control group. Melatonin pretreatment of LPS-stimulated RAW 264.7 cells resulted in the down regulation of 241 genes and up regulation of 164 genes. Interestingly, among genes related to macrophage-mediated immunity, LPS increased the expression of seven genes (Adora2b, Fcgr2b, Cish, Cxcl10, Clec4n, Il1a, and Il1b) and decreased the expression of one gene (Clec4a3). These changes in expression were attenuated by melatonin.... -
Gender-Related Differences in a Process of the Age-Dependent Alterations of the Elements in Monkey Sino-Atrial Node
HiroyasuSatoh, SetsukoTohno, TakeshiMinami, TakaoOishi, MotoharuHayashi, YoshiyukiTohno 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.5 1 249-256 (8 pages)
Gender differences in the trace elements of monkey sino-atrial (SA) node were investigated in a process of age-dependent alterations. Sixty hearts from Japanese and rhesus monkeys (30 male and 30 female) used were aged ranging from 1-day- to 30-year-old. The elements were analyzed using an inductively coupled plasma-atomic emission spectrometer (ICP-AES). Advancing age decreased all the trace elements. Ca, P, S and Mg significantly decreased. The correlation coefficients of Ca and P were... -
Buffering Contribution of Mitochondria to the [Ca2+]i Increase by Ca2+ Influx through Background Nonselective Cation Channels in Rabbit Aortic Endothelial Cells
YoungChulKim, SangJinLee, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.1 5 29-36 (8 pages)
To prove the buffering contribution of mitochondria to the increase of intracellular Ca2+ level ([Ca2+]i) via background nonselective cation channel (background NSCC), we examined whether inhibition of mitochondria by protonophore carbonylcyanide m-chlorophenylhydrazone (CCCP) affects endothelial Ca2+ entry and Ca2+ buffering in freshly isolated rabbit aortic endothelial cells (RAECs). The ratio of fluorescence by fura-2 AM (R340/380) was measured in RAECs. Biological state was checked by... -
Changes of Polyamine Metabolism and Delayed Neuronal Degeneration of Hippocampus after Transient Cerebral Ischemia in Mongolian Gerbils
신경호(Kyung-Ho Shin), 신화정(Hwa-Jung Shin), 이영재(Young-Jae Lee), 김형건(Hyung-Gun Kim), 최상현(Sang-Hyun Choi), 천연숙(Yeon-Sook Chun), 전보권(Boe-Gwun 대한약리학회 대한약리학잡지 12 Pages
대한약리학회 대한약리학잡지 1996, 제 32권 제 3호 4 323-334 (12 pages)
Male Mongolian gerbils (60 ~ 80g) were given DL-difluoromethylornithine (DFMO; 250mg/kg, ip) and methylglyoxal bis(guanylhydrazone) (MGBG; 50 mg/k, ip), respectively, 1 h prior to transient (7 min) occlusion of bilateral common carotid arteries (OBC7) and a daily dose of one of them for 6 days after recirculation, and the polyamine contents, activities of ornithine and S-adenosylmethionine decarboxylases (ODC and SAM-DC), and light microscopic findings of the hippocampus were evaluated. The... -
뇌허혈 손상에 있어서 해마-세포외액내 Glutamate와 Polyamine 농도의 변동에 관한 연구
신경호(Kyung-Ho Shin), 김형건(Hyung-Gun Kim), 최상현(Sang-Hyun Choi), 조소현(So-Hyun Cho), 천연숙(Yeon-Sook Chun), 전보권(Boe-Gwun Chun) 대한약리학회 대한약리학잡지 18 Pages
대한약리학회 대한약리학잡지 1994, 제 30권 제 3호 2 273-290 (18 pages)
뇌-허혈후 나타나는 신경세포의 손상에 glutamate의 과다한 유리와 그의 N-methyl-D-aspartate (NMDA) 수용체: calcium 통로 활성작용 및 polyamine중 putrescine의 증가로 인한 신경세포내 [Ca2+]의 상승과 관련 있다는 보고들이 있다. 본 연구에서는 Mongolian gerbil에서 5분간 경동맥을 차단하여 뇌-허혈을 가한후 재관류시 해마의 세포외액내 polyamine, glutamate, acetylcholine농도, 해마의 [3H]MK-801 결합능의 변동 및 해마조직소견의 변동에 미치는 비가역성 ornithine decarboxylase (ODC) 억제제인 difluoromethylornithine... -
백서의 조건회피반응-유지에 대한 경련성 전기충격의 저해작용에 미치는 CDP-Choline, Aminoguanidine, 및 Difluoromethylornithine의 영향에 관한 연구 : 뇌내 Acetylcholine과 Polyamine 함량-변동에 연관하여
김형건(Hyung-Gun Kim), 김창현(Chang-Hyun Kim), 최상현(Sang-Hyun Choi), 임숙영(Suk-Young Ihm), 이민수(Min-Soo Lee), 전보권(Boe-Gwun Chun) 대한약리학회 대한약리학잡지 14 Pages
대한약리학회 대한약리학잡지 1992, 제 28권 제 2호 1 115-128 (14 pages)
Two-way shuttle box에서 active conditioned response (ACR)을 10일간 매일 30회 부하하여 10회 이상 반응한 웅성 Wistar 백서를 이용하여, 경련성 전기충격 (ECS: 50 mA, 100 Hz, 1.5 sec)에 의한 ACR-유지의 변동에 미치는 CDP-choline (250 mg/kg/day/CC), aminoguanidine (100 mg/kg/day: AG), α-difluoromethylornithine (250 mg/kg/day, DO), 및 spermine (10/mg/kg/day: SM) 각각의 10일간 복강내-주사의 영향을 검토하였다. 그 결과, 10일간 획득된 ACR은 그 다음 10일후에 더욱 증가되었으며, 이는 일일 간격의 5회 ECS... -
간-부분절제(肝-部分切除) 후 나타나는 재생과정(再生過程)에서 교감신경계(交感神經系)의 역할(役割)에 관(關)한 연구(硏究)
최상현(Sang-Hyun Choi), 이중근(Joong-Geun Lee), 박청산(Chung-San Park), 전보권(Boe-Gwun Chun), 천연숙(Yeon-Sook Chun) 대한약리학회 대한약리학잡지 8 Pages
대한약리학회 대한약리학잡지 1990, 제 26권 제 2호 10 177-184 (8 pages)
간-부분절제후 재생과정에서 간 polyamine 대사에 교감신경계가 촉진적으로 간여하는지를 확인하기 위하여 본 실험을 시행하였다. Guanethidine 25mg/kg를 1회 (G-1), 또는 매일 1회씩 3(G-3), 5(G-5) 및 6일간(G-6) 각각 복강내-주사하고, diethyl ether 마취하에서 웅성 백서의 간을 부분(70.4 ± 1.99%)-절제하여, 절제 전후의 혈압, 혈장 catecholamine치 및 간 polyamine 함량의 변동을 검토하여 다음의 성적을 얻었다. 1. 백서 꼬리에서 측정한 정상 수축기 혈압은 98.0 ± 3.9mmHg이며, 이는 G-1에 별 영향을 받지 않았으나, G-3,... -
생체의 Polyamine-분석을 위하여 FNBT-유도체를 이용하는 간편하고 특이적이며 예민한 Isocratic RP-HPLC 분석법과 재생성 흰쥐-간의 Polyamine-대사의 변동에 관한연구
최상현(Sang-Hyun Choi), 김형건(Hyung-Gun Kim), 박홍익(Hong-Ik Park), 전보권(Boe-Gwun Chun) 대한약리학회 대한약리학잡지 8 Pages
대한약리학회 대한약리학잡지 1988, 제 24권 제 2호 9 233-240 (8 pages)
복잡한 시료-전처리과정을 배제하여 간편하고 선택적이며 예민한 polyamine 측정방법으로써 4-fluoro-3-nitrobenzotrifluoride (FNBT)유도체 및 단일이동상을 이용하는 역상의 고속액체 크로마토 그래피 (HPLC) 방법과 아울러 이 방법을 이용한 흰쥐의 재생성간내 polyamine대사의 변동에 관한 관찰-결과를 요약하면 다음과 같다. 1. 간내-polyamine은 0.4M perchloric acid에 추출한 후 Spragg와 Hutchings의 방법에 따라서 FNBT로 N-2 -nitro-4 -trifluoromethylphenyl polyamine (NTP-polyamine) 유도체를 만들고 이를HPLC로 분석... -
Effects of Systemic and Focal Hypoxia on the Activities of Rostral Ventrolateral Medullary Neurons in Cats
Yan, Hai-Dun, Kim, Charn, Kim, Ji-Mok, Lim, Won-Il, Kim, Sang-Jeong, Kim, Jun 대한생리학회 대한생리학회지 12 Pages
대한생리학회 대한생리학회지 1996, 제 30권 제 1호 11 105-116 (12 pages)
Rendering the brain ischemic would evoke the cerebral ischemic reflex which is characterized by an arterial pressor response, apnea and bradycardia. Since the rostral ventrolateral medulla (RVLM) is known to play a key role in the maintenance of normal cardiopulmonary activity, during the cerebral ischemic reflex some cardiac related cells should be excited and respiration related cells inhibited. In this context, the responses of RVLM neurons to systemie and focal hypoxia were analyzed in the... -
The Action of Acetylcholine on the End-Plate Potential
Koh, Il-Sup 대한생리학회 대한생리학회지 8 Pages
대한생리학회 대한생리학회지 1975, 제 9권 제 2호 6 41-48 (8 pages)
The failure of the action potential at the end-plate membrane to reach the sodium equilibrium potential is due to the stimulating action of acetylcholine on Na+-K+ pump. This action of acetylcholine causes an enormous increase in the K+ transport rate. The quantitative amount of potassium ions in the inside of the end-plate membrane prevented the permeability of sodium ions during the depolarization phase of the action potential. It would favor the changes in the shape of action potential by... -
Suppression of Melanose Caused by Diaporthe citri on Citrus Leaves Pretreated with Bio-sulfur
Yong Ho Shin, Eun Ju Ko, Su Jeong Kim, He Nam Hyun, Yong Chull Jeun 한국식물병리학회 The Plant Pathology Journal 8 Pages
한국식물병리학회 The Plant Pathology Journal 2019, 35권 5호 3 417-424 (8 pages)
Melanose, caused by Diaporthe citri, is one of severe diseases in citrus, a major economic resource in Jeju island. To reduce the usage amount of organic synthetic fungicide, bio-sulfur was tested as an alternative chemical to control citrus melanose in the present study. Direct antifungal activity of bio-sulfur against D. citri was determined through in vitro experiment using artificial nutrient media. Disease severity of melanose on bio-sulfur pretreated citrus leaves was lower than that on... -
Purification and Characterization of a Major Extracellular Chitinase from a Biocontrol Bacterium, Paenibacillus elgii HOA73
한국식물병리학회 The Plant Pathology Journal 11 Pages
한국식물병리학회 The Plant Pathology Journal 2017, 33권 3호 10 318-328 (11 pages)
Chitinase-producing Paenibacillus elgii strain HOA73 has been used to control plant diseases. However, the antimicrobial activity of its extracellular chitinase has not been fully elucidated. The major extracellular chitinase gene (PeChi68) from strain HOA73 was cloned and expressed in Escherichia coli in this study. This gene had an open reading frame of 2,028 bp, encoding a protein of 675 amino acid residues containing a secretion signal peptide, a chitin-binding domain, two fibronectin type... -
Control of Basal Stem Rot Disease in Oil Palm by Supplementation of Calcium, Copper, and Salicylic Acid
한국식물병리학회 The Plant Pathology Journal 11 Pages
한국식물병리학회 The Plant Pathology Journal 2016, 32권 5호 3 396-406 (11 pages)
Continuous supplementation of mineral nutrients and salicylic acid (SA) as foliar application could improve efficacy in controlling basal stem rot (BSR) disease in oil palm seedling. It is revealed from the results that the highest disease severity index (58.3%) was recorded in T8 treatments at 9 months after inoculation. The best disease control was achieved by T7 treatments (calcium/copper/SA [Ca/Cu/SA]) (5.0%) followed by T1 (5.5%), T5 (5.8%), T3 (8.3%), T6 (8.3%), T4 (13.3%), and T2 (15.8%)... -
Development of a Selective Medium for the Fungal Pathogen Cylindrocarpon destructans Using Radicicol
한국식물병리학회 The Plant Pathology Journal 5 Pages
한국식물병리학회 The Plant Pathology Journal 2014, 30권 4호 11 432-436 (5 pages)
The soil-borne ascomycete fungus Cylindrocarpon destructans causes ginseng root rot disease and produces various secondary metabolites such as brefeldin A and radicicol. The slow growth of this fungus compared with other plant pathogenic and saprophytic fungi in soil disturbs isolation of this fungus from soil and infected ginseng. In this study, we developed a selective medium for C. destructans using radicicol produced by this fungus. Supplementing 50 mg/L of radicicol to medium inhibited the... -
Note : Open Access ; Development of a Selective Medium for the Fungal Pathogen Fusarium graminearum Using Toxoflavin Produced by the Bacterial Pathogen Burkholderia glumae
한국식물병리학회 The Plant Pathology Journal 5 Pages
한국식물병리학회 The Plant Pathology Journal 2013, 29권 4호 11 446-450 (5 pages)
The ascomycete fungus Fusarium graminearum is a major causal agent for Fusarium head blight in cereals and produces mycotoxins such as trichothecenes and zearalenone. Isolation of the fungal strains from air or cereals can be hampered by various other airborne fungal pathogens and saprophytic fungi. In this study, we developed a selective medium specific to F. graminearum using toxoflavin produced by the bacterial pathogen Burkholderia glumae. F. graminearum was resistant to toxoflavin, while... -
Examination of Correlations Between Several Biochemical Components and Powdery Mildew Resistance of Flax Cultivars
한국식물병리학회 The Plant Pathology Journal 7 Pages
한국식물병리학회 The Plant Pathology Journal 2012, 28권 2호 3 149-155 (7 pages)
A field trial was conducted in 2009/2010 and 2010/2011 growing seasons at Giza Agricultural Research Station to examine correlations between some biochemical componets and powdery mildews (PMs) resistance in flax cultivars. Nine flax cultivars could be divided into five distinct groups, i.e., highly susceptible (Cortland and C.I. 2008), moderately susceptible (Giza 7, and Marshall), moderately resistant (Cass), resistant (Koto, Dakota and Wilden), and highly resistant (Ottowa 770B). The... -
Response of Bentgrass Cultivars to Microdochium nivale Isolates Collected from Golf Courses
한국식물병리학회 The Plant Pathology Journal 10 Pages
한국식물병리학회 The Plant Pathology Journal 2011, 27권 3호 4 232-241 (10 pages)
Pink snow mold, caused by Microdochium nivale, is a major disease on cool season turfgrasses in golf courses in northern Unites States. The relative susceptibility of 17 commercial cultivars of three bentgrass species (creeping, colonial and velvet bentgrass) to Microdochium nivale and the aggressiveness of M. nivale eight isolates obtained from infected turfgrasses on golf courses in Wisconsin were evaluated under controlled conditions. For the field trial, susceptibility of 2 year-old 12... -
Effective Estimation Software cost using Test Generations
Sattarova Feruza, Farkhod Alisherov 인문사회과학기술융합학회 예술인문사회융합멀티미디어논문지 10 Pages
인문사회과학기술융합학회 예술인문사회융합멀티미디어논문지 2011, 제 1권 제 1호 1 1-10 (10 pages)
In software engineering, we have many problems particularly with software cost estimation and the assessment of the evaluation model. Software cost estimation mainly depends on two factors which are the estimation consistency and estimation accuracy. These are very much important to the perfect development of the software without any drawbacks to it. In the past there have been many models and techniques that have failed to give the correct software estimation that really challenges the all... -
Denitration Effect by Non-thermal Plasma
Hyun Choon Kang, Yong Yi Park, Myung Whan Hwang, Seong Joong Kim, In sung Woo, Yeun Seon Kim 한국열환경공학회 열환경공학 8 Pages
한국열환경공학회 열환경공학 2005, 제 2권 1호 4 31-46 (8 pages)
The surface discharge induced plasma chemical process(SPCP) was applied to decompose nitric oxide(NO). The operating condition was optimized in order to maximize the NO decomposition efficiency. The highest NO decomposition efficiency obtained was 94.3% at the power consumption of 19.8 W for the frequency of 10 kHz. NO decomposition efficiency increased with increasing residence time or with decreasing initial concentration of NO. As the thickness and melting point of the electrode increased,... -
DTF를 이용한 석탄가스화기 내의 회분 융착 거동에 관한 이론 해석
최병철, 김형택, 임병표 한국열환경공학회 열환경공학 9 Pages
한국열환경공학회 열환경공학 2005, 제 2권 1호 3 21-29 (9 pages)
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PCBs함유 폐기물 처리를 위한 플라즈마 용융기술
박현서, 송현선, 박동화, 유병수 한국열환경공학회 열환경공학 17 Pages
한국열환경공학회 열환경공학 2011, 제 8권 1호 7 51-67 (17 pages)
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Melting Characteristics of Simulated Non-combustible Radioactive Wastes in a Plasma Torch Melter System
Seung-Chul Park, Hyun-Je Cho, Cheon-Woo Kim 한국열환경공학회 열환경공학 7 Pages
한국열환경공학회 열환경공학 2011, 제 8권 3호 7 53-59 (7 pages)
water cooling refractory melter, an waste feeder, a slag tapping equipment, etc. Especially, the high-technology of a dual mode operation of plasma torch is realized with the invention of the KHNP-CRI patented power supply system. Among a series of dual mode performance tests, a 24-hour melting test for typical surrogate non-combustible waste is introduced in this paper. Electrical currents and voltages of the system was well confined under the operation limits at the test. And the slag melt was... -
한국교육모델 대안 탐색을 위한 소고:아프리카교육 문제와의 비교를 기반으로
한국교육행정학회 교육행정학연구 2017, 제 35권 제 2호 9 209-226 (18 pages)
대한민국의 교육모델은 세계성을 갖출 수 있을 것인가가 본 논문의 질문이다. 이 논문에서 는 질문에 대한 답을 위해 기존 설명방식을 검토하고 특히 당면한 아프리카교육의 사례와 비 교를 통해 그 한계점과 대안을 탐색하였다. 선행연구들을 살펴보면 현재까지 밝혀져 온 한국 교육발전의 요인들로서는 첫째 역사문화적 요인으로서 교육열과 숭문주의, 둘째 정책적 노력 요인으로서 저비용 양적성장정책, 셋째 초등학교에서부터 중학교 고등학교 그리고 대학으로 순차적인 단계를 밟은 발전 전략, 넷째 사립학교와 민간재원 의존 전략이...
