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The effect of enamel matrix derivative (EMD) in combination with deproteinized bovine bone material (DBBM) on the early wound healing of rabbit calvarial defects
김유석, 장현선, 박주철, 김흥중, 이종우, 김종관, 김병옥, Kim. You-Seok, Jang. Hyun-Seon, Park. Ju-Chol, Kim. Heoung-Jung, Lee. Jong-Woo, Kim. Chong-Kwan, Kim. Byun 대한치주과학회 대한치주과학회지 18 Pages
대한치주과학회 대한치주과학회지 2005, Vol.35 No.1 199-216 (18 pages)
상실된 치주조직의 형태적, 기능적 재건이다. 법랑기칠 단백질 유도체(enamel matrix derivative: EMD)는 치주 병소에 사용시 상피세포의 증식을 억제하며 치주인대 및 백악아세포를 활성화시켜 무세포성 백악질 및 치주인대와 골조직의 생성을 유도한다고 보고되고 있다. 또한 법랑기질 단백칠 유도체는 골모세포의 증식 및 분화를 촉진시키며 alkaline phosphatase의 활성 및 mineralized nodule의 형성을 촉진시킨다고 보고되고 있다. 이에 본 연구에서는 토끼 두개골 결손부에 법랑기질 단백질 유도체와 이종골 이식재를 이식한 후... -
Synthesis and Characterization of New Poly(terphenylene vinylene)Derivative as Bule Emitting Material
김윤희, 안준환, 신동철, 김준학, 박영욱, 최돈수, 김영관, 권순기, Kim. Yun Hui, An. Jun Hwan, Sin. Dong Cheol, Kim. Jun Hak, Park. Yeong Uk, Choe. Don Su, Kim. Yeong Gw 대한화학회 Bulletin of the Korean Chemical Society 2 Pages
대한화학회 Bulletin of the Korean Chemical Society 2001, Vol.22 No.11 1181-1182 (2 pages)
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The Water-Soluble Chitosan Derivative, N-Methylene Phosphonic Chitosan, Is an Effective Fungicide against the Phytopathogen Fusarium eumartii
Florencia Anabel Mesas, Mar?a Cecilia Terrile, Mar?a Ximena Silveyra, Adriana Zu?iga, Mar?a Susana Rodriguez, Claudia Anah? Casalongu?, Julieta Ren?e Mendieta 한국식물병리학회 The Plant Pathology Journal 10 Pages
한국식물병리학회 The Plant Pathology Journal 2021, 37권 6호 4 533-542 (10 pages)
Chitosan has been considered an environmental-friend- ly polymer. However, its use in agriculture has not been extended yet due to its relatively low solubility in water. N-Methylene phosphonic chitosan (NMPC) is a water- soluble derivative prepared by adding a phosphonic group to chitosan. This study demonstrates that NMPC has a fungicidal effect on the phytopathogenic fungus Fusarium solani f. sp. eumartii (F. eumartii) judged by the inhibition of F. eumartti mycelial growth and spore... -
The expression of plasmid mediated afimbrial adhesin genes in an avian septicemic Escherichia coli strain
Eliana Guedes Stehling, *, Tatiana Amabile Campos, Marcelo Brocchi, Vasco Ariston de Carvalho Azevedo, Wanderley Dias da Silveira 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 1호 10 75-83 (9 pages)
An Escherichia coli strain (SEPT13) isolated from the liver of a hen presenting clinical signs of septicaemia had a LD50 of 4.0 × 105 CFU/ml in one-day-old chickens, expressed Ia, Ib, E1, E3, K and B colicins and aerobactin. The strain was ampicillin and streptomycin resistant, and found to have fimA, csgA and tsh DNA related sequences; it could adhere to and invade HEp-2 and tracheal epithelial cells, expressed fimbriae (observed by electron microscopy), and had five plasmids of 2.7, 4.7,... -
Cystic endometrial hyperplasia and endometritis in a dog following prolonged treatment of medroxyprogesterone acetate
Kyung-Suk Kim, Okjin Kim 대한수의학회 Journal of Veterinary Science 2 Pages
대한수의학회 Journal of Veterinary Science 2005, 제 6권 제 1호 13 81-82 (2 pages)
gross findings of uterus were enlarged lesions in two areas of the left horn, which had thickened wall and yellowish sticky material in the lumen. Histopathologically, cystic endometrial hyperplasia (CEH) and endometritis were present in the thickened area. In this case, CEH and endometritis may be attributed to prolonged treatment of MPA. It was concluded that further study is needed to clarify the association of MPA treatment with age, its pathogenesis and abnormal uterine changes in dogs. -
Cap-independent protein translation is initially responsible for 4-(N-methylnitrosamino)-1-(3-pyridyl)-butanone (NNK)-induced apoptosis in normal human bronchial pithelial cells
Seo-Hyun Moon, Hyun-Woo Kim, Jun-Sung Kim, Jin-Hong Park, Hwa Kim, Gook-Jong Eu, Hyun-Sun Cho, Ga-Mi Kang, Kee-Ho Lee, Myung-Hai 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2004, 제 5권 제 4호 13 369-378 (10 pages)
Evidences show that eukaryotic mRNAs can perform protein translation through internal ribosome entry sites (IRES). 5'-Untranslated region of the mRNA encoding apoptotic protease-activating factor 1 (Apaf-1) contains IRES, and, thus, can be translated in a cap-independent manner. Effects of changes in protein translation pattern through rapamycin pretreatment on 4-(methylnitrosamino)-1-(3-pyridyl)-butanone(NNK, tobacco-specific lung carcinogen)-induced apoptosis in human bronchial epithelial... -
Immunologic reactivity of a lipopolysaccharide-protein complex of type A Pasteurella multocida in mice
Hyo-ik Ryu, Chul-joong Kim 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2000, 제 1권 제 2호 5 87-95 (9 pages)
The immunologic reactivity of a lipopolysaccharide (LPS)-protein complex isolated from a potassium thiocyanate extract of a Pasteurella multocida (capsular type A and somatic type 3) strain was evaluated in mice. The LPS-protein complex provided 100% protection in mice against a challenge with the homologous strain. However, when the complex was fractionated into LPS and protein moieties by phenol-water treatment, both components lacked immunogenicity. The complex and extracted components were... -
Expression of the S glycoprotein of transmissible gastroenteritis virus (TGEV)in transgenic potato and its immunogenicity in mice
Dong Joo Ahn , Jung Won Youm , Suk Weon Kim , Won Kee Yoon , Hyoung Chin Kim , Tai Young Hur , Young Hee Joung , Jae Heu 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 8 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2013, 제 53권 제 4호 5 217-224 (8 pages)
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Immunotherapy with methyl gallate, an inhibitor of Treg cell migration, enhances the anti-cancer effect of cisplatin therapy
HyunseongKim, GihyunLee, Sung-HwaSohn, ChanjuLee, JungWonKwak, HyunsuBae 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.3 5 261-268 (8 pages)
Foxp3+ CD25+CD4+ regulatory T (Treg) cells are crucial for the maintenance of immunological self-tolerance and are abundant in tumors. Most of these cells are chemo-attracted to tumor tissues and suppress anti-tumor responses inside the tumor. Currently, several cancer immunotherapies targeting Treg cells are being clinically tested. Cisplatin is one of the most potent chemotherapy drugs widely used for cancer treatment. While cisplatin is a powerful drug for the treatment of multiple cancers,... -
The Effect of Methanol on the Structural Parameters of Neuronal Membrane Lipid Bilayers
Hyung-JinJoo, Shin-HoAhn, Hang-RaeLee, Sung-WooJung, Chang-WonChoi, Min-SeokKim, Moon-KyoungBae, In-KyoChung, Soo-KyoungBae, Hye-OckJang, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.4 5 255-264 (10 pages)
The structures of the intact synaptosomal plasma membrane vesicles (SPMVs) isolated from bovine cerebral cortexs, and the outer and the inner monolayer separately, were evaluated with 1,6-diphenyl- 1,3,5-hexatriene (DPH) and 1,3-di(1-pyrenyl)propane (Py-3-Py) as fluorescent reporters and trinitrophenyl groups as quenching agents. The methanol increased bulk rotational and lateral mobilities of SPMVs lipid bilayers. The methanol increased the rotational and lateral mobilities of the outer... -
Pretreatment of Albino Rats with Methanolic Fruit Extract of Randia Dumetorum (L.) Protects against Alcohol Induced Liver Damage
ArshadAliNoorani, MohanK.Kale 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.2 7 125-130 (6 pages)
Alcohol abuse and its medical and social consequences are a major health problem in many areas of the world. The present study was conducted to evaluate the protective effect of methanolic fruit extract of Randia dumetorum (L.) on alcohol-induced liver damage in rats. Rats were divided into five different groups (n=6), group I served as a control, group II received ethanol (3 ml/100 g/day p.o.), group III served as standard group and received silymarin (50 mg/kg p.o.), group IV and V served as... -
Chronic Opium Treatment Can Differentially Induce Brain and Liver Cells Apoptosis in Diabetic and Non-diabetic Male and Female Rats
MajidAsiabanha, GholamrezaAsadikaram, AmirRahnema, MehdiMahmoodi, GholamhoseinHasanshahi, MohammadHashemi6, MohammadKhaksari 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.6 2 327-332 (6 pages)
It has been shown that some opium derivatives promote cell death via apoptosis. This study was designed to examine the influence of opium addiction on brain and liver cells apoptosis in male and female diabetic and non-diabetic Wistar rats. This experimental study was performed on normal, opium-addicted, diabetic and diabetic opium-addicted male and female rats. Apoptosis was evaluated by TUNEL and DNA fragmentation assays. Results of this study showed that apoptosis in opium-addicted and... -
The Efficacy of Shikonin on Cartilage Protection in a Mouse Model of Rheumatoid Arthritis
YoungOckKim, SeungJaeHong, Sung-VinYim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.4 1 199-204 (6 pages)
The potential therapeutic action of shikonin in an experimental model of rheumatoid arthritis (RA) was investigated. As a RA animal model, DBA/1J mice were immunized two times with type II collagen. After the second collagen immunization, mice were orally administered shikonin (2 mg/kg) once a day for 35 days, and the incidence, clinical score, bone mineral density (BMD), bone mineral content (BMC) and joint histopathology were evaluated. BMD in the proximal regions of the tibia largely... -
Anti-ischemic Effect of Polygala Tenuifolia in Isolated Rat Heart
Chang-WonKang, Jong-HoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.3 3 89-95 (7 pages)
Polygala tenuifolia (PT) is one of the most well-known traditional herbal medicines in Korea which is commonly used for the treatment of cardiovascular symptoms. The anti-ischemic effects of PT in isolated rat heart was investigated by analyzing changes in blood pressure, aortic flow, coronary flow, and cardiac output. And, its underlying mechanism was examined by quantitating intracellular calcium content in rat neonatal cardiomyocytes. Rats were divided into two groups: an ischemia-induced... -
What is the Key Step in Muscle Fatty Acid Oxidation after Change of Plasma Free Fatty Acids Level in Rats?
Kyung-OhDoh, Sang-DugSuh, Jong-YeonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.3 7 173-178 (6 pages)
The purpose of this study was to discern the critical point in skeletal muscle fatty acid oxidation by changing plasma free fatty acids (FFA) level in rat. In the study, 3 key steps in lipid oxidation were examined after changing plasma FFA level by acipimox. The rates of both palmitate and palmitoyl- carnitine oxidation were decreased by decrease of plasma FFA level, however, carnitine palmitoyl transferase (CPT) 1 activity was not changed, suggesting CPT1 activity may not be involved in the... -
Lorazepam이 가토 혈중 주정농도에 미치는 영향에 관한 실험적 연구
대한신경정신의학회 신경정신의학 1977, 제 16권 제 4호 3 340-348 (9 pages)
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Dibenzepine이 가토 혈중 주정농도에 미치는 영향에 관한 실험적 연구
대한신경정신의학회 신경정신의학 1980, 제 19권 제 1호 6 40-46 (7 pages)
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GS 283의 평활근 억제 작용기전
김시환(Si Hwan Kim), 이영수(Young Soo Lee), 정원석(Won Seog Chong), 장기철(Ki Churl Chang) 대한약리학회 대한약리학잡지 10 Pages
대한약리학회 대한약리학잡지 1994, 제 30권 제 1호 11 101-110 (10 pages)
Tetrahydroisoquinoline유도체인 GS 283의 약리학적 특성을 흰쥐 흉부대동맥, 기니픽 결장띠 및 토끼 장간막 동맥 및 흰쥐 뇌를 사용하여 조사하였다. 혈관 평활근에서 GS283은 고 K+에 의한 수축을 농도 의존적으로 억제하여 Ca2+ 길항작용을 보였다. 또한α1- 수용체 자극에 의한 수축도 억제하였다. GS 283의 혈관이완 작용은 propranolol영향을 받지 않으므로 β-수용체 자극작용에 의한 것이 아니었다. 세포내 칼슘이온과 근장력 변화를 동시에 측정하였을 때 GS 283의 억제효과는 조직내 형광의 증가를 수반했다. 이 증가는 fura... -
흰쥐 장관에 있어 칼륨에 의해 활성화되는 칼슘 채널에 대한 Cyclobuxine E의 영향
이종화(Jong-Hwoa Lee), 권준택(Jun-Tack Kwon), 조병헌(Byung-Heon Cho), 최규홍(Kyu-Hong Choi), 김유재(Yu-Jae Kim), 김종배(Jong Bae Kim), 김천숙(Chun-Sook Kim 대한약리학회 대한약리학잡지 6 Pages
대한약리학회 대한약리학잡지 1989, 제 25권 제 1호 6 53-58 (6 pages)
본 연구실에는 최근 수년동안 말라리아, 성병등에 민간약으로 사용되어 온 회양목(Buxus microphylla var. koreana Nakai)으로 부터 다수의 물질을 분리하여 그 약리작용을 경색하여왔다. Coumarin의 유도체인 buxuletin은 이뇨 작용이 있음이 인정되었으며, steroid 성 alkaloid인 Cyclobuxine D(C25H42ON2)는 항염증작용, 흰쥐에서 심박동수 감소작용 및 적출 평활근 이완 작용을 나타냈다. 본 연구에서는 회양목에서 Cyclobuxine D의 유도체인 Cyclobuxine E(C24H38ON2)를 분리하여 그 구조를 이화학적인 방법으로 규명하였으며 흰쥐의... -
가토 두개골에서 Bio-glass와 자가골 이식에 관한 실험적 연구
위현철, 임병섭, 정세화, 박창주, 임재중, 황경균, 심광섭 대한치과이식임플란트학회 Journal of Dental Implant Research 12 Pages
대한치과이식임플란트학회 Journal of Dental Implant Research 2007, 제 26권 2호 2 11-22 (12 pages)
구강내 골 결손을 회복하기 위해 골이식술의 재료로 자가골은 gold standard1) 로 알려져 왔지만 골 결손부 의 크기나 형태, 적절한 공여부 조직의 부족, 이차적 인 수술적 접근으로 인한 부담 등은 자가골 이용의 제 한 요인이기도 하다2). 또한 자가골은 이식부에 거부 반응 없이 생착되는 반면 그 흡수량이 예측 불가능하 고 이식골의 종류, 고정의 방식, 골화 기원에 따라 많 은 영향을 받는다. -
Identification, Characterization, and Efficacy Evaluation of Bacillus velezensis for Shot-Hole Disease Biocontrol in Flowering Cherry
Viet-Cuong Han, Nan Hee Yu, Hyeokjun Yoon, Neung-Ho Ahn, Youn Kyoung Son, Byoung-Hee Lee, Jin-Cheol Kim 한국식물병리학회 The Plant Pathology Journal 16 Pages
한국식물병리학회 The Plant Pathology Journal 2022, 38권 2호 5 115-130 (16 pages)
Though information exists regarding the pathogenesis of the shot-hole disease (SH) in flowering cherry (FC), there has been a lack of research focusing on SH management. Therefore, here, we investigated the inhibitory activities of antagonistic bacteria against SH pathogens both in vitro and in vivo as well as their biochemical characteristics and bioactive compounds. Two biosurfactant- producing bacterial antagonists, identified as Bacillus velezensis strains JCK-1618 and JCK-1696, exhibited... -
A Review of the Potency of Plant Extracts and Compounds from Key Families as an Alternative to Synthetic Nematicides: History, Efficacy, and Current Developments
Abraham Okki Mwamula, Md. Faisal Kabir, DongWoon Lee 한국식물병리학회 The Plant Pathology Journal 25 Pages
한국식물병리학회 The Plant Pathology Journal 2022, 38권 2호 1 53-77 (25 pages)
The global nematicides market is expected to continue growing. With an increasing demand for synthetic chemical-free organic foods, botanical nematicides are taking the lead as replacements. Consequently, in the recent years, there have been vigorous efforts towards identification of the active secondary metabolites from various plants. These include mostly glucosinolates and their hydrolysis products such as isothiocyanates; flavonoids, alkaloids, limonoids, quassinoids, saponins, and the more... -
Role of Trehalose Synthesis in Ralstonia syzygii subsp. indonesiensis PW1001 in Inducing Hypersensitive Response on Eggplant (Solanum melongena cv. Senryo-nigou)
Nur Laili, Takafumi Mukaihara, Hidenori Matsui, Mikihiro Yamamoto, Yoshiteru Noutoshi, Kazuhiro Toyoda, Yuki Ichinose 한국식물병리학회 The Plant Pathology Journal 14 Pages
한국식물병리학회 The Plant Pathology Journal 2021, 37권 6호 7 566-579 (14 pages)
Ralstonia syzygii subsp. indonesiensis (Rsi, former name: Ralstonia solanacearum phylotype IV) PW1001, a causal agent of potato wilt disease, induces hypersen- sitive response (HR) on its non-host eggplant (Solanum melongena cv. Senryo-nigou). The disaccharide treha- lose is involved in abiotic and biotic stress tolerance in many organisms. We found that trehalose is required for eliciting HR on eggplant by plant pathogen Rsi PW1001. In R. solanacearum, it is known that the OtsA/ OtsB pathway is... -
A Genome-Wide Analysis of Antibiotic Producing Genes in Streptomyces globisporus SP6C4
Da-Ran Kim, Youn-Sig Kwak 한국식물병리학회 The Plant Pathology Journal 7 Pages
한국식물병리학회 The Plant Pathology Journal 2021, 37권 4호 8 389-395 (7 pages)
Soil is the major source of plant-associated microbes. Several fungal and bacterial species live within plant tissues. Actinomycetes are well known for producing a variety of antibiotics, and they contribute to improving plant health. In our previous report, Streptomyces glo- bisporus SP6C4 colonized plant tissues and was able to move to other tissues from the initially colonized ones. This strain has excellent antifungal and antibacterial activities and provides a suppressive effect upon... -
Inhibitory Effect of Moriniafungin Produced by Setosphaeria rostrata F3736 on the Development of Rhizopus Rot
Min Young Park, So Jung Park, Jae-Jin Kim, Dong Ho Lee, Beom Seok Kim 한국식물병리학회 The Plant Pathology Journal 9 Pages
한국식물병리학회 The Plant Pathology Journal 2020, 36권 6호 4 570-578 (9 pages)
a known sordarin derivative, which showed minimum inhibitory concentrations of 1-8 μg/ml against Colletotrichum spp. and 0.03-0.13 μg/ml against Rhizopus spp. in vitro. Moriniafungin showed protective control efficacies against Rhizopus rot on apple and peach fruits. Treatment with 25 μg/ ml moriniafungin delimited the lesion diameter significantly by 100% on R. oryzae-inoculated apple fruits compared with the non-treated control. Treatment with 0.04 μg/ml of moriniafungin reduced the lesion... -
Effects of Salicylic Acid and Indole Acetic Acid Exogenous Applications on Induction of Faba Bean Resistance against Orobanche crenata
Fatima Zahra Briache, Mounia Ennami, Joseph Mbasani-Mansi, Assia Lozzi, Abdelhadi Abousalim, Walid El Rodeny, Moez Amri, Zine El Abidine Triqui, Rachid Mentag 한국식물병리학회 The Plant Pathology Journal 15 Pages
한국식물병리학회 The Plant Pathology Journal 2020, 36권 5호 10 476-490 (15 pages)
The parasitic weed, Orobanche crenata, is one of the most devastating constraint for faba bean production in Mediterranean regions. Plant host defense induction was reported as one of the most appropriate control methods in many crops. The aim of this study was to elucidate the effect of salicylic acid (SA) and indole acetic acid (IAA) on the induction of faba bean resistance to O. crenata under the field and controlled experimental conditions. Both hormones were tested on two contrasting faba... -
vfr, A Global Regulatory Gene, is Required for Pyrrolnitrin but not for Phenazine-1-carboxylic Acid Biosynthesis in Pseudomonas chlororaphis G05
Xia Wu, Xiaoyan Chi, Yanhua Wang, Kailu Zhang, Le Kai, Qiuning He, Jinxiu Tang, Kewen Wang, Longshuo Sun, Xiuying Hao, Weihai Xie, Yihe Ge 한국식물병리학회 The Plant Pathology Journal 11 Pages
한국식물병리학회 The Plant Pathology Journal 2019, 35권 4호 7 351-361 (11 pages)
In our previous study, pyrrolnitrin produced in Pseudomonas chlororaphis G05 plays more critical role in suppression of mycelial growth of some fungal pathogens that cause plant diseases in agriculture. Although some regulators for pyrrolnitrin biosynthesis were identified, the pyrrolnitrin regulation pathway was not fully constructed. During our screening novel regulator candidates, we obtained a white conjugant G05W02 while transposon mutagenesis was carried out between a fusion mutant...
