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전체 선택해제
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본문검색 결과만 보기
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Notch, Snail, and Polycomb Repressive Complex 2 SupportHuman Mesenchymal Stem Cell Migration by High Glucose
Ji Young Oh, Jung Min Ryu, Sei Jung Lee, Hyun Jik Lee, Eun Ju Song, Ki Hoon Lee, Dah Ihm Kim, Jeong Yeon Kim, Gee Euhn Choi, So Hee Ko, Ho 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 271 483-483 (1 pages)
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Anti-osteoarthritis effect of a combinational treatment with human adipose tissue-derived mesenchymal stem cells and thrombospondin 2 in rabbits
Eun Suk An, Kyung ha Shin, Ye seul Cha, Ban Young Hwan, Hai yu Guo, Da Woom Seo, Jung Min You, Ehn Kyoung Choi, Yun Bae Kim 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 377 396-396 (1 pages)
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Effect of stacking sequence on the flexural and fracture properties of carbon/basalt/epoxy hybrid composites
Jae Il Lim, Kyong Yop Rhee, Hyun Ju Kim, Dong Ho Jung 한국탄소학회 Carbon Letters 4 Pages
한국탄소학회 Carbon Letters 2014, Vol.15 No.2 9 125-128 (4 pages)
In this study, the effect of stacking sequence on the flexural and fracture properties of carbon/ basalt/epoxy hybrid composites was investigated. Two types of carbon/basalt/epoxy hybrid composites with a sandwich form were fabricated: basalt skin-carbon core (BSCC) composites and carbon skin-basalt core (CSBC) composites. Fracture tests were conducted and the fracture surfaces of the carbon/basalt/epoxy hybrid composites were then examined using scanning electron microscopy (SEM). The results... -
Effect of donor age on the proliferation and multipotency of canine adipose-derived mesenchymal stem cells
Jienny Lee, Keum Sil Lee, Chan-Lan Kim, Jeong Su Byeon, Na-Yeon Gu, In-Soo Cho, Sang-Ho Cha 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 2호 3 141-148 (8 pages)
Research into adipose tissue-derived mesenchymal stem cells (AD-MSCs) has demonstrated the feasibility of their use in clinical applications due to their ease of isolation and abundance in adipose tissue. We isolated AD-MSCs from young and old dogs, and the cells were subjected to sequential sub-passaging from passage 1 (P1) to P7. Canine AD-MSCs (cAD-MSCs) were examined for proliferation kinetics, expression of molecules associated with self-renewal, expression of cell surface markers, and... -
Comparison of the effects of muscle stretching exercises and cupping therapy on pain thresholds, cervical range of motion and angle
Jong-eun Yim, Jun-hyuck Park, Hong-seop Kim, Ju-yeon Woo, So-yeong Joo, Su-min Lee, Je-won Song 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2017, 제 6권 제 2호 6 83-89 (7 pages)
Objective: Computers and smartphones have become a necessity for modern people, and the use of these things in an inappropriate position has increased the number of people who complain about neck problems. The purpose of this study was to compare the changes of cervical angle, range of motion (ROM) and pain threshold according to the McKenzie stretching and dry cupping therapy. Design: Cross-over design. Methods: We included 12 male and 6 female college students in their twenties, and conducted... -
Effects of performing hip abduction and adduction during bridging exercise on trunk and lower extremity muscle activity in healthy individuals
Joo Young Hwang, Woo Young Ahn, Hyo Jae Kim, Je Hyun Woo, Woo Jin Choi, Jae Wook Park, Mi Young Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2017, 제 6권 제 1호 3 14-19 (6 pages)
Objective: To investigate the effect of performing three different bridge exercise conditions on the activities of four different muscles using surface electromyography (sEMG) in healthy young adults. Design: Cross-sectional study. Methods: A total of 20 healthy young adults (10 males, 10 females) voluntarily participated in this study. All subjects randomly performed three different bridge conditions as follows: general bridge exercise, isometric hip abduction (IHAB) with a blue Theraband... -
Relationship between anticipatory postural adjustment of the trunk, dual tasks and physical performance with chronic stroke survivors
Won Jeong Hwang, Min Kwon Cho, Yi-jung Chung 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2015, 제 4권 제 1호 8 44-48 (5 pages)
Objective: The purpose of this study was to investigate the relationship between anticipatory postural adjustment (APA), single task, dual tasks and physical performances. The trunk muscles of APA consist of bilateral erector spinae (ES) and bilateral internal oblique (IO) adnominal muscles, during rapid stepping with the affected or unaffected leg in a sitting posture. Design: Cross-sectional study. Methods: In patients with chronic stroke, electrodes of surface electromyography (EMG) were... -
The potential role of COX-2 in cancer stem cell-mediated canine mammary tumor initiation: an immunohistochemical study
Jian Huang, Di Zhang, Fuqiang Xie, Degui Lin 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 2호 13 225-231 (7 pages)
tumor initiation and maintenance. Additionally, it is becoming apparent that cyclooxygenase (COX) signaling is associated with canine mammary tumor development. The goals of the present study were to investigate COX-2 expression patterns and their effect on CSC-mediated tumor initiation in primary canine mammary tissues and tumorsphere models using immunohistochemistry. Patterns of COX-2, CD44, octamer-binding transcription factor (Oct)-3/4, and epidermal growth factor receptor (EGFR) expression... -
Toxic effects of methylmercury, arsanilic acid and danofloxacin on the differentiation of mouse embryonic stem cells into neural cells
Seok-Jin Kang, Sang-Hee Jeong, Eun-Joo Kim, Young-Il Park, Sung-Won Park, Hyo-Sook Shin, Seong-Wan Son, Hwan-Goo Kang* 대한수의학회 Journal of Veterinary Science 11 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 1호 7 61-71 (11 pages)
This study was performed to assess the neurotoxic effects of methylmercury, arsanilic acid and danofloxacin by quantification of neural-specific proteins in vitro. Quantitation of the protein markers during 14 days of differentiation indicated that the mouse ESCs were completely differentiated into neural cells by Day 8. The cells were treated with non-cytotoxic concentrations of three chemicals during differentiation. Low levels of exposure to methylmercury decreased the expression of GABAA-R... -
A modified method for inducing periodontitis in dogs using a silk-wire twisted ligature
Se Eun Kim, Eui Ri Lee, Yesran Lee, Manbok Jeong, Young Woo Park, Jae Sang Ahn, Jeong Taek Ahn, Kangmoon Seo* 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2012, 제 13권 제 2호 11 193-197 (5 pages)
This study was designed to assess the effectiveness of a modified silk ligature twisted with wire for inducing advanced periodontitis. Periodontitis was induced in five premolars and one molar of 20 healthy dogs over a 60-day period. The dogs were divided into four groups according to the ligature- inducing materials used: soft moistened food only, wire ligature (WL), silk ligature (SL) and twisted ligature with silk and wire (SWL). Periodontal indices were recorded, and dental radiographs were... -
Translocational changes of localization of synapsin in axonal sprouts of regenerating rat sciatic nerves after ligation crush injury
Ku-birm Kwon, Jin-suk Kim, Byung-joon Chang 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2000, 제 1권 제 1호 1 1-9 (9 pages)
Time-dependent translocational changes of Synapsin I (SyI), a synaptic vesicle-associated phosphoprotein and its involvement in the axonal transport were investigated in the regenerating axonal sprouts. A weak SyI immunoreactivity (IR) was found in the axoplasm of normal axons. Rat sciatic nerves were crush-injured by ligating with 1-0 silk thread at the mid-thigh level and released from the ligation 24 h later. At various times after release, immunocytochemistry was performed. SyI was... -
CEPHALOMETRIC CHARACTERISTICS OF OPEN-BITE CASES WITH DEGENERATIVE JOINT DISEASE(DJD) OF TMJ
Tae Woo Kim 대한치과교정학회 The Korean Journal of Orthodontics 10 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1995, 제 25권 제 6호 2 665-674 (10 pages)
The purpose of this study is to investigate the cephalometric characteristics of the open-bite patients with DJD of TMJ. The DJD open-bite cases were compared with normal samples and Class II open-bite cases with normal TMJ respectively. Twenty three open-bite patients with bilateral DJD of TMJ(13.9~35.3 years old, Group I) were selected from the Department of Orthodontics, SNUDH. Group II consisted of thirteen Class II open-bite cases(13.2-27.4 years old) with no TMD signs/symtoms and good... -
백서 부분적 설절제가 하악골 성장에 미치는 영향에 관한 실험적 연구
현석환(Sug-Hwan Hyun), 김광원(Kwang-Won Kim) 대한치과교정학회 The Korean Journal of Orthodontics 9 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1995, 제 25권 제 5호 5 567-575 (9 pages)
이 연구의 목적은 부분적 설절제가 백서 하악골의 성장에 미치는 영향을 규명하기 위함이다. 생후 4주령의 옹서백서를 두 집단으로 분류하였다. 첫번째 집단은 대조군으로 사용하고 두번째 집단은 부분적으로 설절제를 시행한 집단이다. 이 실험동물은 부분적인 설절제 후 4주와 8주에 희생되었다. 부분적인 설절제 후 쥐의 하악성장변화는 건조 골표본에 의해 관찰되었다. 이 연구로부터 얻어진 결과는 다음과 같다. 1. 성장기 백서의 설절제는 하악골 자체의 형태에는 영향을 미치지 못하였으나 전반적인 하악골 성장의 감소를... -
혀의 크기와 위치 및 두개안면골격이 치열공극에 미치는 영향에 관한 연구
김선화(Sun-Hwa Kim), 박수병(Soo-Byung Park), 손우성(Woo-Sung Son) 대한치과교정학회 The Korean Journal of Orthodontics 14 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1996, 제 26권 제 5호 14 623-636 (14 pages)
뚜렷한 국소적 요인없이 상악이나 하악 또는 상하악 모두에서 전반적인 공극을 보이는 55명과 상하악에서 심한 총생을 보이는 32명을 선정하여 혀크기 및 위치를 계측비교하여, 이 중 상하악 모두에서 전반적인 공극을 보이는 군을 대상으로 두개안면골격 및 치열궁 크기를 계측하여 총생치열군과의 차에 대한 유의성 검정 및 혀와 두개안면골격 그리고 치열궁 사이의 상관관계를 조사하여 다음과 같은 결론을 얻었다. 1. 혀의 길이는 상악공극치열군이 가장 컸고 총생치열군에서 가장 작게 나타났으며, 혀의 위치는 상악공극치열군에서... -
전치부 반대교합 성인의 저작양상에 관한 연구
손병화(Byung-Wha Sohn), 유형석(Hyung-Seog Yu), 박종진(Jong-Jin Park) 대한치과교정학회 The Korean Journal of Orthodontics 10 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1997, 제 27권 제 1호 3 35-44 (10 pages)
저작은 기본적으로 Brain system의 central pattern generator(CPG)에 의해 조절되면, CPG로 부터 target 기관까지의 출력(output)은 oral sensory seedback에 의해 변형된다. 전치부 반대교합은 이 feedback mechanism에 영향을 미치어 muscle activity와 jaw movement를 바꾼다. 본 연구는 정상교합자와 전치부 반대교합자의 muscle activity와 jaw movement pattern의 차이를 알고자 시행하였다. 대상은 각각 성인 남녀 30명씩으로 하였으며 측정은 Biopak system의 EMG와 EGN을 사용하여 얻은 결과는 다음과 같다. 1. Resting시... -
삼각피판법을 이용한 편측 불완전 구순열 환자의 구순 교정 수술-증례 보고
송인석, 홍종락, 정필훈, 서병무 대한구순구개열학회 대한구순구개열학회지 7 Pages
대한구순구개열학회 대한구순구개열학회지 2007, 제 10권 2호 1 67-73 (7 pages)
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Parry-Romberg Syndrome 환자에서 악정형 및 교정 치료
유국호, 백형선 대한구순구개열학회 대한구순구개열학회지 10 Pages
대한구순구개열학회 대한구순구개열학회지 2012, 제 15권 1호 1 1-10 (10 pages)
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Epigallocatechin-3-Gallate (EGCG) Attenuates Traumatic Brain Injury by Inhibition of Edema Formation and Oxidative Stress
BoZhang, BingWang, ShuhuaCao, YongqiangWang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.6 3 491-497 (7 pages)
of disorders, the effect of EGCG on TBI remains unknown. In this study, a weight drop model was established to evaluate the therapeutic potential of EGCG on TBI. Rats were administered with 100 mg/kg EGCG or PBS intraperitoneally. At different times following trauma, rats were sacrificed for analysis. It was found that EGCG (100 mg/kg, i.p.) treatment significantly reduced brain water content and vascular permeability at 12, 24, 48, 72 hour after TBI. Real-time PCR results revealed that EGCG... -
Bacterial PAMPs and Allergens Trigger Increase in [Ca2+]i-induced Cytokine Expression in Human PDL Fibroblasts
Ga-YeonSon, DongMinShin, JeongHeeHong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.3 15 291-297 (7 pages)
activator of NF-κB ligand and osteoprotegerin) and intracellular Ca2+-involved effect. Bacterial pathogens and allergic mediators induced increased expression of pro-inflammatory cytokines, and these results are dependent on intracellular Ca2+. However, bacterial pathogens and allergic mediators did not lead to increased expression of bone remodeling mediators, except lipopolysaccharide-induced effect on receptor activator of NF-κB ligand expression. These experiments provide evidence that a... -
Role of Cerebrospinal Fluid Biomarkers in Clinical Trials for Alzheimer’s Disease Modifying Therapies
Ju-HeeKang, Na-YoungRyoo, DongWunShin, JohnQTrojanowski, LeslieM.Shaw 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.6 1 447-456 (10 pages)
Until now, a disease-modifying therapy (DMT) that has an ability to slow or arrest Alzheimer’s disease (AD) progression has not been developed, and all clinical trials involving AD patients enrolled by clinical assessment alone also have not been successful. Given the growing consensus that the DMT is likely to require treatment initiation well before full-blown dementia emerges, the early detection of AD will provide opportunities to successfully identify new drugs that slow the course of AD... -
Mutant p53-Notch1 Signaling Axis Is Involved in Curcumin-Induced Apoptosis of Breast Cancer Cells
Yun-HeeBae, JongHyoRyu, Hyun-JooPark, KwangRokKim, Hee-JunWee, Ok-HeeLee, Hye-OckJang, Moon-KyoungBae, Kyu-WonKim, Soo-KyungBae 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.4 6 291-297 (7 pages)
activator of the Notch1 in MDA-MB-231 cells, and explore the role of this mutant p53-Notch1 axis in curcumin-induced apoptosis. We found that curcumin treatment resulted in an induction of apoptosis in MDA-MB-231 cells, together with downregulation of Notch1 and its downstream target, Hes1. This reduction in Notch1 expression was determined to be due to the decreased activity of endogenous mutant p53. We confirmed the suppressive effect of curcumin on Notch1 transcription by performing a Notch1... -
Increased HoxB4 Inhibits Apoptotic Cell Death in Pro-B Cells
Sung-WonPark, Kyung-JongWon, Yong-SooLee, HyeSunKim, Yu-KyungKim, Hyeon-WooLee, BokyungKim, ByeongHanLee, Jin-HoiKim, Dong-KuKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.4 6 265-271 (7 pages)
investigated the effect of overexpressed HoxB4 on cell survival under various conditions that induce death, using the Ba/F3 cell line. Analysis of phenotypical characteristics showed that HoxB4 overexpression in Ba/F3 cells reduced cell size, death, and proliferation rate. Moreover, the progression from early to late apoptotic stages was inhibited in Ba/F3 cells subjected to HoxB4 overexpression under removal of interleukin-3-mediated signal, leading to the induction of cell cycle arrest at the... -
Effects of Isoflurane Anesthesia on Post-Anesthetic Sleep-Wake Architectures in Rats
Hwan-SooJang, Ji-YoungJung, Kwang-HoJang, Maan-GeeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.5 7 291-297 (7 pages)
direct restorative effect. Little is known about the effects of isoflurane anesthesia on sleep homeostasis. We investigated whether 1) isoflurane anesthesia could provide a sleep-like process, and 2) the depth of anesthesia could differently affect the post-anesthesia sleep response. Nine rats were treated for 2 hours with ad libitum sleep (Control), sleep deprivation (SD), and isoflurane anesthesia with delta- wave-predominant state (ISO-1) or burst suppression pattern-predominant state (ISO-2)... -
Inhibition of β-amyloid1-40 Peptide Aggregation and Neurotoxicity by Citrate
YongHoonPark, Young-JinKim, IlHongSon, HyunDukYang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.4 2 273-279 (7 pages)
The accumulation of Ղ-amyloid (AՂ) aggregates is a characteristic of Alzheimer's disease (AD). Furthermore, these aggregates have neurotoxic effects on cells, and thus, molecules that inhibit AՂ aggregate formation could be valuable therapeutics for AD. It is well known that aggregation of AՂ depends on its hydrophobicity, and thus, in order to increase the hydrophilicity of AՂ, we considered using citrate, an anionic surfactant with three carboxylic acid groups. We... -
Differential Effects of Nitric Oxide Synthase Inhibitors in Rats
Jun-HeeLee, ChangYellShin, BongSuKang, JiHoonJeong, KyeongBumChoi, YoungSilMin, JinHakKim, InHoiHuh, UyDongSohn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.2 3 99-104 (6 pages)
aorta. This augmentation by L-NAME or L-NMMA was attenuated with the treatment of NO precursor, arginine. ACh, however, decreased the augmentation induced by L-NMMA, but not by L-NAME. Superoxide dismutase (SOD, 50 u/ml) potentiated an inhibitory effect of ACh on the PE (107 M)-induced contraction. It has been known that platelet activating factor itself induces iNOS. Platelet activating factor (PAF, 107 M) inhibited PE (107 M)-induced contraction. Pretreatment with L-NMMA...
