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전체 선택해제
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본문검색 결과만 보기
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Direct tyrosine phosphorylation of Akt/PKB by epidermal growth factor receptor
배순식, 최장현, 윤성지, 김은경, 오용석, 김치대, 서판길, Bae. Sun-Sik, Choi. Jang-Hyun, Yun. Sung-Ji, Kim. Eun-Kyung, Oh. Yong-Suk, Kim. Chi-Dae, Suh. Pann-Ghill 한국생명과학회 생명과학회지 7 Pages
한국생명과학회 생명과학회지 2007, Vol.17 No.2 185-191 (7 pages)
Akt/PKB는 세포의 증식, 분화, 사멸, 혈관신생 등 매우 많은 생리활성 조절에 있어 매우 중요한 역할을 수행한다. 우리는 Akt/PKB의 tyrosine잔기의 인산화가 $Thr^{308}$ 인산화에 필수적임을 밝혔다. COS-7 세포주에 EGF를 처 리하면 Akt/PKB의 tyrosine 잔기에 인산화가 촉진되었으며 이러한 인산화 촉진은 Akt/PKB에 myristoylation site를 이용해 세포막으로 이동시키면 더욱 더 증가하였다. 특히, 분리된 Akt/PKB와 EGF 수용체를 이용해 인산화 반응을 실시하면 tyrosine잔기의 인산화뿐만 아니라 $Ser^{473}$에 대한 인산화도... -
Expression of DNA-dependent Protein Kinase and Its Relationship with Epidermal Growth Factor Receptor Signaling in Metastatic Cancer Cell Lines
황지영, 김선희, 강치덕, 윤만수, Hwang. Jee Young, Kim. Sun Hee, Kang. Chi Dug, Yoon. Man Soo 한국생명과학회 생명과학회지 9 Pages
한국생명과학회 생명과학회지 2005, Vol.15 No.3 406-414 (9 pages)
암세포의 유전적 불안정성은 부적절하게 활성화된 DNA수복경로와 관련되어 있다. 전이성 암은 높은 유전적 불안정성을 나타내는데, 이와 관련하여 본 연구에서는 전이성 암세포에서의 중요한 DNA수복 단백질의 하나인 DN의존성 단백질 키나아제(DNA-PK)의 발현 변화를 조사하였다. 여러 종류의 전이도가 다른 암세포들을 대상으로 한 실험에서 전이성 암세포들은 각각의 모세포에 비하여 DNA-PK 성분의 조절 소단위인 Ku70/80의 발현 및 Ku의 DNA 결합 활성이 증강되어 있었다. 또한 DNA-PK의 촉매 소단위인 DNA-PKcs의 발현 및 whole... -
Alternative drug therapies are superior to epidermal growth factor receptor -targeted chemotherapeutic drug responses in non-small cell lung cancer
Sikdar. Sourav, Khuda-Bukhsh. Anisur Rahman 탕정한의학회 TANG : International journal of genuine traditional medicine 2 Pages
탕정한의학회 TANG : International journal of genuine traditional medicine 2013, Vol.3 No.2 10-11 (2 pages)
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Comparison of Epidermal Growth Factor Receptor Mutations between Primary Tumors and Lymph Nodes in Non-small Cell Lung Cancer: a Review and Meta-analysis of Published Data
Wang. Feng, Fang. Ping, Hou. Dan-Yang, Leng. Zai-Jun, Cao. Le-Jie 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 5 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2014, Vol.15 No.11 4493-4497 (5 pages)
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Epidermal Growth Factor Receptor Mutations in Non-Small Cell Lung Cancers in a Multiethnic Malaysian Patient Population
Liam. Chong-Kin, Leow. Hwong-Ruey, How. Soon-Hin, Pang. Yong-Kek, Chua. Keong-Tiong, Lim. Boon-Khaw, Lai. Nai-Lang, Kuan. Yeh-Chunn, Pai 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 6 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2014, Vol.15 No.1 321-326 (6 pages)
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Simultaneous Blockage of Epidermal Growth Factor Receptor and Cyclooxygenase-2 in a Human Xenotransplanted Lung Cancer Model
Mu. Xiao-Yan, Dong. Xue-Li, Sun. Jie, Ni. Yu-Hua, Dong. Zhang, Li. Xi-Li, Sun. Er-Lian, Yi. Zhou, Li. Gao 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 5 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2014, Vol.15 No.1 69-73 (5 pages)
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Feasibility Study of Docetaxel and Cyclophosphamide Six- Cycle Therapy as Adjuvant Chemotherapy for Japanese Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer Patients
Abe. Hajime, Mori. Tsuyoshi, Kawai. Yuki, Tomida. Kaori, Kubota. Yoshihiro, Umeda. Tomoko, Tani. Tohru 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 4 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2013, Vol.14 No.8 4835-4838 (4 pages)
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Clinical Significance of Serum p53 and Epidermal Growth Factor Receptor in Patients with Acute Leukemia
Abdel-Aziz. Mohamed Mohamed 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 5 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2013, Vol.14 No.7 4295-4299 (5 pages)
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Relationship between Epidermal Growth Factor Receptor Gene Mutations and Clinicopathological Features in Patients with Non-Small Cell Lung Cancer in Western Turkey
Unal. Olcun Umit, Oztop. Ilhan, Calibasi. Gizem, Baskin. Yasemin, Koca. Dogan, Demir. Necla, Akman. Tulay, Ellidokuz. Hulya, Yilmaz. Ahm 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 5 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2013, Vol.14 No.6 3705-3709 (5 pages)
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Expressional Correlation of Human Epidermal Growth Factor Receptor 2, Estrogen/Progesterone Receptor and Protein 53 in Breast Cancer
Panahi. Marzieh, Saki. Najmaldin, Ashourzadeh. Sara, Rahim. Fakher 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 5 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2013, Vol.14 No.6 3699-3703 (5 pages)
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Differences in Epidermal Growth Factor Receptor Gene Mutations and Relationship with Clinicopathological Features in NSCLC Between Uygur and Han Ethnic Groups
Zhang. Yan, Wang. Qiang, Han. Zhi-Gang, Shan. Li 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 5 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2013, Vol.14 No.5 2879-2883 (5 pages)
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High Resolution Melting Analysis for Epidermal Growth Factor Receptor Mutations in Formalin-fixed Paraffin-embedded Tissue and Plasma Free DNA from Non-small Cell Lung Cancer Patients
Jing. Chang-Wen, Wang. Zhuo, Cao. Hai-Xia, Ma. Rong, Wu. Jian-Zhong 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 5 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2013, Vol.14 No.11 6619-6623 (5 pages)
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Association of Human Epidermal Growth Factor Receptor-2 Expression and Clinicopathological Findings in Patients with Colorectal Cancer
Karaca. Halit, Deniz. Kemal, Berk. Veli, Inanc. Mevlude, Ozkan. Metin 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 5 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2012, Vol.13 No.12 6221-6225 (5 pages)
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Epidermal Growth Factor Receptor-Related DNA Repair and Radiation-Resistance Regulatory Mechanisms: A Mini-Review
Bai. Jing, Guo. Xiao-Guang, Bai. Xiao-Ping 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 3 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2012, Vol.13 No.10 4879-4881 (3 pages)
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Conversion of a murine monoclonal antibody A13 targeting epidermal growth factor receptor to a human monoclonal antibody by guided selection
Chang. Ki-Hwan, Kim. Min-Soo, Hong. Gwang-Won, Shin. Yong-Nam, Kim. Se-Ho 생화학분자생물학회 Experimental & molecular medicine : EMM 8 Pages
생화학분자생물학회 Experimental & molecular medicine : EMM 2012, Vol.44 No.1 52-59 (8 pages)
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Molecular Docking and Molecular Dynamics Simulations of the Kinase Domain Inhibitor for an Epidermal Growth Factor Receptor
Choi. Youngjin, Kang. In-Cheol, Cho. Eunae, Kim. Jaebum, Jeong. Karpjoo, Jung. Seunho 대한화학회 Bulletin of the Korean Chemical Society 4 Pages
대한화학회 Bulletin of the Korean Chemical Society 2013, Vol.34 No.8 2515-2518 (4 pages)
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Design and Synthesis of Novel Epidermal Growth Factor Receptor Kinase Inhibitors
Ha. Jae-Du, Kang. Seung-Kyu, Kim. Kun-Do, Choi. Joong-Kwon, Kong. Jae-Yang, Ahn. Chang-H. 대한화학회 Bulletin of the Korean Chemical Society 7 Pages
대한화학회 Bulletin of the Korean Chemical Society 2005, Vol.26 No.6 959-965 (7 pages)
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Correlation Between $^{18}F$-Fluorodeoxyglucose Uptake and Epidermal Growth Factor Receptor Mutations in Advanced Lung Cancer
Choi. Yun-Jung, Cho. Byoung Chul, Jeong. Yong Hyu, Seo. Hyo Jung, Kim. Hyun Jeong, Cho. Arthur, Lee. Jae Hoon, Yun. Mijin, Jeon. Tae Joo 대한핵의학회 Nuclear medicine and molecular imaging : NMMI 7 Pages
대한핵의학회 Nuclear medicine and molecular imaging : NMMI 2012, Vol.46 No.3 169-175 (7 pages)
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위장관 간질성 종양의 Epidermal Growth Factor Receptor 유전자 돌연변이 연구
유남진, 이종우, 송영화, 전해명, 남석우, 김수영, 박원상, 이정용, 이석형, Yoo. Nam Jin, Lee. Jong Woo, Soung. Young Hwa, Jeon. Hae Myung, Nam. Suk Woo, Kim. Su Young, Park. 대한위암학회 대한위암학회지 4 Pages
대한위암학회 대한위암학회지 2004, Vol.4 No.4 268-271 (4 pages)
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Affinity Maturation of an Epidermal Growth Factor Receptor Targeting Human Monoclonal Antibody ER414 by CDR Mutation
Chang. Ki-Hwan, Kim. Min-Soo, Hong. Gwang-Won, Seo. Mi-Sun, Shin. Yong-Nam, Kim. Se-Ho 대한면역학회 Immune network : official journal of the Korean association of immunobiologists 10 Pages
대한면역학회 Immune network : official journal of the Korean association of immunobiologists 2012, Vol.12 No.4 155-164 (10 pages)
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Apigenin and Wogonin Regulate Epidermal Growth Factor Receptor Signaling Pathway Involved in MUC5AC Mucin Gene Expression and Production from Cultured Airway Epithelial Cells
Sikder. Md. Asaduzzaman, Lee. Hyun Jae, Ryu. Jiho, Park. Su Hyun, Kim. Ju-Ock, Hong. Jang-Hee, Seok. Jeong Ho, Lee. Choong Jae 대한결핵및호흡기학회 Tuberculosis and respiratory diseases : TRD 7 Pages
대한결핵및호흡기학회 Tuberculosis and respiratory diseases : TRD 2014, Vol.76 No.3 120-126 (7 pages)
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Molecular Basis of Drug Resistance: Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors and Anaplastic Lymphoma Kinase Inhibitors
Yang. Sei-Hoon 대한결핵및호흡기학회 Tuberculosis and respiratory diseases : TRD 11 Pages
대한결핵및호흡기학회 Tuberculosis and respiratory diseases : TRD 2013, Vol.75 No.5 188-198 (11 pages)
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Neuroendocrine Differentiation in Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor
Chang. Youjin, Kim. Seon Ye, Choi. Yun Jung, So. Kwang Sup, Rho. Jin Kyung, Kim. Woo Sung, Lee. Jae Cheol, Chung. Jin-Haeng, Choi. Chang 대한결핵및호흡기학회 Tuberculosis and respiratory diseases : TRD 9 Pages
대한결핵및호흡기학회 Tuberculosis and respiratory diseases : TRD 2013, Vol.75 No.3 95-103 (9 pages)
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Autophagy Inhibition with Monensin Enhances Cell Cycle Arrest and Apoptosis Induced by mTOR or Epidermal Growth Factor Receptor Inhibitors in Lung Cancer Cells
Choi. Hyeong Sim, Jeong. Eun-Hui, Lee. Tae-Gul, Kim. Seo Yun, Kim. Hye-Ryoun, Kim. Cheol Hyeon 대한결핵및호흡기학회 Tuberculosis and respiratory diseases : TRD 9 Pages
대한결핵및호흡기학회 Tuberculosis and respiratory diseases : TRD 2013, Vol.75 No.1 9-17 (9 pages)
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Repeated Favorable Responses to Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors in a Case of Advanced Lung Adenocarcinoma
Kim. Eun-Young, Kim. Yoon-Hee, Ban. Hee-Jung, Oh. In-Jae, Kwon. Yong-Soo, Kim. Kyu-Sik, Kim. Yu-Il, Lim. Sung-Chul, Kim. Young-Chul 대한결핵및호흡기학회 Tuberculosis and respiratory diseases : TRD 5 Pages
대한결핵및호흡기학회 Tuberculosis and respiratory diseases : TRD 2013, Vol.74 No.3 129-133 (5 pages)