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Pulmonary Adenocarcinoma with a Micropapillary Pattern Detected by Bronchial Washing - A Brief Case Report -
박재홍, 하승연, 조현이, 정동해, 김나래, 박상희, Park. Jae-Hong, Ha. Seung-Yeon, Cho. Hyun-Yee, Chung. Dong-Hae, Kim. Na-Rae, Park. Sang-Hui 대한세포병리학회 대한세포병리학회지 3 Pages
대한세포병리학회 대한세포병리학회지 2008, Vol.19 No.2 206-208 (3 pages)
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Aerosol delivery of kinase-deficient Akt1 attenuates Clara cell injury induced by naphthalene in the lungs of dual luciferase mice
Arash Minai-Tehrani, Young-Chan Park, Soon-Kyung Hwang, Jung-Taek Kwon, Seung-Hee Chang, Sung-Jin Park, Kyeong-Nam Yu, Ji-Eun Ki 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2011, 제 12권 제 4호 2 309-317 (9 pages)
Conventional lung cancer therapies are associated with poor survival rates; therefore, new approaches such as gene therapy are required for treating cancer. Gene therapies for treating lung cancer patients can involve several approaches. Among these, aerosol gene delivery is a potentially more effective approach. In this study, Akt1 kinase-deficient (KD) and wild-type (WT) Akt1 were delivered to the lungs of CMV-LucR-cMyc-IRES-LucF dual reporter mice through a nose only inhalation system using... -
Distribution and characterization of IL-10-secreting cells in lymphoid tissues of PCV2-infected pigs
Alan R. Doster, Sakthivel Subramaniam, Ji-Young Yhee, Byung-Joon Kwon, Chi-Ho Yu, So-Young Kwon, Fernando A. Osorio, Jung-Hyang 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2010, 제 11권 제 3호 1 177-183 (7 pages)
Distribution and characterization of interlukin-10 (IL-10)- secreting cells in lymphoid tissues of pigs naturally infected with porcine circovirus type 2 (PCV2) were evaluated in accordance with PCV2 antigen detection. After screening a total of 56 pigs showing the symptoms of postweaning multisystemic wasting syndrome (PMWS), 15 pigs were PCV2 positive and 5 pigs, which showed stronger positive signals over multiples tissues were further investigated. This study showed that in PCV2-infected... -
Synergistic effect of ERK inhibition on tetrandrine-induced apoptosis in A549 human lung carcinoma cells
Hyun Sun Cho, Seung Hee Chang, Youn Sun Chung, Ji Young Shin, Sung Jin Park, Eun Sun Lee, Soon Kyung Hwang, Jung Taek Kwon, Aras 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2009, 제 10권 제 1호 4 23-28 (6 pages)
Tetrandrine (TET), a bis-benzylisoquinoline alkaloid from the root of Stephania tetrandra, is known to have anti-tumor activity in various malignant neoplasms. However, the precise mechanism by which TET inhibits tumor cell growth remains to be elucidated. The present studies were performed to characterize the potential effects of TET on phosphoinositide 3-kinase/Akt and extracellular signal-regulated kinase (ERK) pathways since these signaling pathways are known to be responsible for cell... -
Tissue distribution of bovine viral diarrhea virus antigens in persistently infected cattle
Taekyun Shin, Helen Acland 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2001, 제 2권 제 2호 2 81-84 (4 pages)
The tissue distribution and cellular localization of viral antigens in three cattle with persistent bovine viral diarrhea virus (BVDV) infection was studied. In three cases, necropsy findings of oral ulcers, abmasal ulcers and necrosis of Peyer's patches were suspected have been caused by BVDV infection. Non-cytopathic BVDV was isolated from a tissue pool of liver, kidneys and spleen. Immunohistochemical detection of BVDV showed that BVDV antigens were detected in both epithelial and... -
Overexpression of cyclin D1 and cyclin E in 1,2-dimethylhydrazine dihydrochloride-induced rat colon carcinogenesis
Kwon Hur, Jung-Rae Kim, Byung-Il Yoon, Jung-Keun Lee, Jae-Hoon Choi, Goo-Taeg Oh, Dae-Yong Kim 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2000, 제 1권 제 2호 9 121-126 (6 pages)
Deregulation of G1 cyclins has been reported in several human and rodent tumors including colon cancer. To investigate the expression pattern of G1 cyclins in 1,2- dimethyl-hydrazine dihydrochloride (DMH)-induced rat colon carcinogenesis, we studied the expression of cyclin D1 and cyclin E by quantitative reverse transcription-polymerase chain reaction (RT-PCR) analysis and immunohistochemistry (IHC). The mRNA level of cyclin D1 was increased 1.2-fold in adenocarcinomas but not significantly in... -
Prevalence of porcine parvovirus in pigs with postweaning multisystemic wasting syndrome in Jeju Island
Kyeong Nam Ko , Ji Youl Jung , Sang Chul Kang , Ki Seung Kim , Jae Hoon Kim , Dae Yong Kim , Eui Kyung Hwang 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 6 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2011, 제 51권 제 3호 4 203-208 (6 pages)
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NecroX-5 exerts anti-inflammatory and anti-fibrotic effects via modulation of the TNFα/Dcn/TGFβ1/Smad2 pathway in hypoxia/reoxygenation-treated rat hearts
VuThiThu, HyoungKyuKim, LeThanhLong, ToThanhThuy, NguyenQuangHuy, SoonHaKim, NariKim, KyungSooKo, ByoungDooRhee, JinHan 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.3 10 305-314 (10 pages)
Inflammatory and fibrotic responses are accelerated during the reperfusion period, and excessive fibrosis and inflammation contribute to cardiac malfunction. NecroX compounds have been shown to protect the liver and heart from ischemia-reperfusion injury. The aim of this study was to further define the role and mechanism of action of NecroX-5 in regulating infl ammation and fi brosis responses in a model of hypoxia/reoxygenation (HR). We utilized HR-treated rat hearts and lipopolysaccharide... -
The Inhibitory Mechanism of Gentamicin on Electrical Field Stimulation Response in Rat Bladder Smooth Muscle
ChangHoMin, YiYiWang, JinhyungBae, JungHoonHan, UyDongSohn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.5 11 473-478 (6 pages)
To see the inhibitory mechanism of gentamicin in response to electrical field stimulation (EFS) using the rat bladder smooth muscle, atropine or guanethidine was treated but had no effect. Methylsergide, a non-selective 5-HT1, 5-HT2 receptor antagonist was also treated but had on effect. Kinase inhibitors, such as chelerythrine (PKC inhibitor), ML-9 (MLCK inhibitor), or Y27632 (rho kinase inhibitor) were pretreated before gentamicin treatment, but did not have effect. For U73122, a phospholipase... -
Calcium Sensitization Induced by Sodium Fluoride in Permeabilized Rat Mesenteric Arteries
EnyueYang, JoonYongCho, UyDongSohn, InKyeomKim, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.1 8 51-57 (7 pages)
It was hypothesized that NaF induces calcium sensitization in Ca2＋-controlled solution in permeabilized rat mesenteric arteries. Rat mesenteric arteries were permeabilized with Ղ- escin and subjected to tension measurement. NaF potentiated the concentration-response curves to Ca2＋ (decreased EC50 and increased Emax). Cumulative addition of NaF (4.0, 8.0 and 16 mM) also increased vascular tension in Ca2＋-controlled solution at pCa 7.0 or pCa 6.5, but not at pCa 8.0. NaF-induced... -
Calcium Channel Blocking and Phosphodiesterase Inhibitory Action of GS386, a Dihydroisoquinoline Derivative, in Isolated Rat Trachea
장기철(Ki Churl Chang), 이회영(Hoi Young Lee), 강영진(Young Jin Kang), 구의본(Eui Bon Koo) 대한약리학회 대한약리학잡지 8 Pages
대한약리학회 대한약리학잡지 1996, 제 32권 제 3호 8 373-380 (8 pages)
Recently we reported that GS 386, 1-(4 -methoxybenzyl)-6,7-dimethoxy-3,4-dihydroisoquinoline, inhibited amplitude of the Ca2+ current by reducing the probability of Ca2+ channel opening without changing channel kinetics in isolated rabbit atrial myocyte. In the present study, further investigation of the mechanism of action of GS 386 was performed using isolated rat trachealis. GS 386 concentration-dependently relaxed rat trachealis contracted by carbachol (0.3μM) and high K+(65.4 mM) with IC50... -
폐의 원발성 악성 섬유성 조직구종의 기관지솔질과 기관지세척 검사의 세포학적 소견 - 1예 보고 -
박미옥, 안욱수, Park. Mi-Ok, Ahn. Wook-Su 대한세포병리학회 대한세포병리학회지 5 Pages
대한세포병리학회 대한세포병리학회지 1999, Vol.10 No.2 151-155 (5 pages)
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기도의 선양 낭종암의 세포학적 소견 - 2례 보고 -
조영미, 박소영, 이인철, Cho. Young-Mee, Park. So-Young, Lee. In-Chul 대한세포병리학회 대한세포병리학회지 5 Pages
대한세포병리학회 대한세포병리학회지 1995, Vol.6 No.2 214-218 (5 pages)
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폐암의 세포병리학적 진단에 관한 검토
박인애, 함의근, Park. In-Ae, Ham. Eui-Keun 대한세포병리학회 대한세포병리학회지 8 Pages
대한세포병리학회 대한세포병리학회지 1991, Vol.2 No.1 20-27 (8 pages)
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객담도말 음성인 폐결핵환자의 기관지세척액에서 Amplicor PCR과 IS61110 PCR의 임상적 유용성에 관한 비교 연구
이준구, 김영삼, 박재민, 고원기, 양동규, 김세규, 장준, 김성규, 최종락, Lee. Jun-Gu, Kim. Young-Sam, Park. Jae-Min, Ko. Won-Ki, Yang. Dong-Goo, Kim. Se-Kyu, Chang. Joon, Ki 대한결핵및호흡기학회 결핵 및 호흡기 질환 9 Pages
대한결핵및호흡기학회 결핵 및 호흡기 질환 2001, Vol.50 No.2 213-221 (9 pages)
연구배경 : 임상에서 흉부 엑스선상 폐결핵이 의심되나 객담 도말에서 음성이거나 객담배출을 못하는 환자에서 신속한 진단을 위해 기관지세척액에서 상품화된 Roche사의 Amplcor M. tuberculosis kit와 IS6110 in-house PCR의 유용성을 알아보고자 하였다. 방 법 : 객담 항산균도말에서 음성인 환자 혹은 결핵과 감별진단이 필요한 환자를 대상으로 기관지내시경을 시행하여 기관지세척액에서 항산균 도말, 결핵균배양, IS6110 PCR검사법, Roche사의 Amplicor PCR를 동시에 시행하였다. 결 과 : 기관지 세척액을 통한 항산균도말에서... -
기관지암종 진단에 있어서 객담과 기관지 세척액 검사의 유용성 - 기관지경 검사를 통해 확진된 예를 대신으로 -
김준미, 민수기, 주영채, 조철호, Kim. Joon-Mee, Min. Soo-Kee, Chu. Young-Chae, Cho. Chul-Ho 대한세포병리학회 대한세포병리학회지 7 Pages
대한세포병리학회 대한세포병리학회지 2001, Vol.12 No.1 17-23 (7 pages)
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폐종양의 세포학적 진단에서 경기관지세침흡인검사의 유용성
김태엽, 공경엽, 김원동, 김온자, Kim. Tae-Yub, Gong. Gyung-Yub, Kim. Won-Dong, Kim. On-Ja 대한세포병리학회 대한세포병리학회지 6 Pages
대한세포병리학회 대한세포병리학회지 1997, Vol.8 No.2 109-114 (6 pages)
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폐에 전이된 점액표피양 암종의 세포병리학적 소견
박원서, 함의근, Park. Weon-Seo, Ham. Eui-Keun 대한세포병리학회 대한세포병리학회지 4 Pages
대한세포병리학회 대한세포병리학회지 1994, Vol.5 No.2 180-183 (4 pages)
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폐결핵환자에서 기관지 세척액의 Adenosine deaminase(ADA) 임상적 의의
김남수, 천기태, 이흥범, 이용철, 이양근, Kim. Nam-Su, Cheon. Ki-Tae, Lee. Heung-Bum, Lee. Yong-Chul, Rhee. Yang-Keun 대한결핵및호흡기학회 결핵 및 호흡기 질환 6 Pages
대한결핵및호흡기학회 결핵 및 호흡기 질환 1999, Vol.47 No.5 595-600 (6 pages)
목 적: 폐흉수에서 ADA 활성도의 측정은 결핵성 폐흉수의 진단에 유용한 검사로 증명되어왔다. 하지만 기관지 폐포 세척액에서 ADA의 유용성에 대해서는 논란이 많으며 또한 그 연구가 극히 미미한 실정이다. 본 연구는 폐결핵의 조기진단의 생화학적 지표로서 결핵환자의 기관지 세척액 ADA의 유용성을 알아보고자 하였다. 대상 및 방법: 폐결핵이 확진된 경우를 제 1군(25명)으로 하였고 폐암환자들을 제 2군(26명)으로 하였으며 대조군을 제 3군(10명)으로 하여 기관지 세척액 ADA 활성도에 있어서 세군 사이에 차이가 있는지를 비교... -
기관지 세척액 검사를 이용한 MAGE 유전자 검사의 임상적 의의
이승준, 윤명재, 이성태, 오혜진, 송숙희, 손인, 김연정, 한경훈, 김선희, 김수현, Lee. Seung-June, Yun. Myung-Jae, Lee. Seong-Tae, Oh. Hye-Jin, Song. Sook-Hee, Sohn. In, Kim. Ye 대한결핵및호흡기학회 Tuberculosis and respiratory diseases : TRD 8 Pages
대한결핵및호흡기학회 Tuberculosis and respiratory diseases : TRD 2010, Vol.69 No.6 442-449 (8 pages)
