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전체 선택해제
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본문검색 결과만 보기
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Neuroprotective effect of Sigesbeckia pubescens extract onglutamate-induced oxidative stress in HT22 cells via downregulation of MAPKs and caspase pathway
Rashedunnabi Aka, In shik Kim, Dong choon Ahn, Hyun Jin Tae, Gi Beum Kim, Byung Yong Park 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 294 353-353 (1 pages)
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ROS Generation, MAPKs Activation, mTOR Inhibition, Leads Autophagy and Lysosomal Degradation in Naringin Induced Cell Death in AGS Cancer Cells
Suchismita Raha, Gon Sup Kim, Silvia Yumnam, Venu Venkatarame Gowda Saralamma, Ho Jeong Lee, Jeong Doo Heo, Sang Joon Lee, Eun Hee Kim 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 283 346-347 (2 pages)
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Cell-type Specific Activation of MAPKs in the Progression of Gastric Ulcer in Rats
유리, 권영삼, 오태호, 김태환, 박상준, Yu. Ri, Kwon. Young Sam, Oh. Tae-Ho, Kim. Tae-Hwan, Park. Sang-Joon 한국임상수의학회 Journal of veterinary clinics 7 Pages
한국임상수의학회 Journal of veterinary clinics 2013, Vol.30 No.5 339-345 (7 pages)
진행에 있어 MAPKs의 세포특이적 활성에 관한 연구결과들에 대해서는 잘 알려져 있지 않다. 본 연구에서는 이부프로펜에 의해 유도된 위궤양의 진행에 있어 활성화된 MAPKs가 다양한 세포들에 어떻게 분포하는지를 실험하였다. 위궤양 유발은 200 mg/kg 이부프로펜을 하루에 8시간간격으로 3번 투여하였다. 동물부검은 이부프로펜을 투여한 후 24, 48, 72시간에 실시하였고, 위조직은 면역조직화학 및 웨스턴블랏에 사용되었다. 활성화된 p-ERK는 정상 랫드 위점막상피의 위상피증식층에서만 주로 발현되었으나, 이부프로펜을 투여한 후... -
Anti-inflammatory effect of methanol extract from Erigeron Canadensis L. may be involved with upregulation of heme oxygenase-1 expression and suppression of $NF{kappa}B$ and MAPKs activation in macrophages
Sung. Jeehye, Sung. Misun, Kim. Younghwa, Ham. Hyeonmi, Jeong. Heon-Sang, Lee. Junsoo 한국영양학회 Nutrition research and practice 8 Pages
한국영양학회 Nutrition research and practice 2014, Vol.8 No.4 352-359 (8 pages)
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대식세포에서 MAPKs 및 PI3K/AKT 신호전달계 활성을 통한 괴각 추출물의 prostaglandin E2 및 tumor necrosis factor-α 생성의 촉진
강영순, 한민호, 이문희, 홍수현, 박흥식, 정재철, 이정래, 이은우, 강경화, 김철민, 김병우, 최영현, Kang. Young-Soon, Han. Min Ho, Lee. Moon Hee, Hong. Su Hyun, Park. Heungsik, Jung. Ja 한국생명과학회 생명과학회지 7 Pages
한국생명과학회 생명과학회지 2013, Vol.23 No.11 1397-1403 (7 pages)
$PGE_2$ 및 $TNF-{alpha}$의 생성을 촉진하였으며, 이는 cyclooxygenase-2 (COX-2)와 $TNF-{alpha}$ 유전자의 전사 및 번역 수준에서의 활성화와 연관성이 있었다. 또한 FSE 처리에 의하여 다양한 종류의 cytokine 발현의 증가를 cytokine array 분석을 통하여 확인하였으며, RAW 264.7 대식세포의 활성화에는 mitogen-activated protein kinases (MAPKs) 및 phosphatidylinositol-3-kinase (PI3K)/Akt 경로 활성화가 연관되어 있음을 알 수 있었다. 본 연구의 결과는 괴각 추출물이 면역 증강제로서의 개발 가능성이 매우 높음을... -
Exopolysaccharide-Overproducing Lactobacillus paracasei KB28 Induces Cytokines in Mouse Peritoneal Macrophages via Modulation of NF-${kappa}B$ and MAPKs
Kang. Hee, Choi. Hye-Sun, Kim. Ji-Eun, Han. Nam-Soo 한국미생물생명공학회 Journal of microbiology and biotechnology 5 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2011, Vol.21 No.11 1174-1178 (5 pages)
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An Ester Extract of Cochinchina Momordica Seeds Induces Differentiation of Melanoma B16 F1 Cells via MAPKs Signaling
Zhao. Lian-Mei, Han. Li-Na, Ren. Feng-Zhi, Chen. Shu-Hong, Liu. Li-Hua, Wang. Ming-Xia, Sang. Mei-Xiang, Shan. Bao-En 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 8 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2012, Vol.13 No.8 3795-3802 (8 pages)
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Induction of Apoptosis and Transient Increase of Phosphorylated MAPKs by Diallyl Disulfide Treatment in Human Nasopharyngeal Carcinoma CNE2 Cells
Zhang. Yi Wei, Wen. Jun, Xiao. Jian Bo, Talbot. Simon G., Li. Gloria C., Xu. Ming 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 7 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2006, Vol.29 No.12 1125-1131 (7 pages)
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Mitogen-Activated Protein Kinases (MAPKs) Mediate SIN-1/ Glucose Deprivation-Induced Death in Rat Primary Astrocytes
Yoo. Byoung-Kwon, Choi. Ji-Woong, Choi. Min-Sik, Ryu. Mi-Kyoung, Park. Gyu-Hwan, Jeon. Mi-Jin, Ko. Kwang-Ho 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 6 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2005, Vol.28 No.8 942-947 (6 pages)
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Activation of Antioxidant-Response Element (ARE), Mitogen- Activated Protein Kinases (MAPKs) and Caspases by Major Green Tea Polyphenol Components during Cell Survival and Death
Chen. Chi, Yu. Rong, Owuor. Edward D., Kong. A.NTony 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 8 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2000, Vol.23 No.6 605-612 (8 pages)
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Bone Morphogenetic Protein 2-induced MAPKs Activation Is Independent of the Smad1/5 Activation
Jun. Ji-Hae, Ryoo. Hyun-Mo, Woo. Kyung-Mi, Kim. Gwan-Shik, Baek. Jeong-Hwa 대한구강생물학회 International journal of oral biology : official journal of the Korean Academy of Oral Biology and t 7 Pages
대한구강생물학회 International journal of oral biology : official journal of the Korean Academy of Oral Biology and t 2009, Vol.34 No.2 115-121 (7 pages)
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목향에탄올추출물의 ROS-MAPKs 경로를 통한 세포사멸 유도
김대성, 이성진, 이장천, 우원홍, 임규상, 문연자, Kim. Dae-Sung, Lee. Sung-Jin, Lee. Jang-Cheon, Woo. Won-Hong, Lim. Kyu-Sang, Mun. Yeun-Ja 대한약학회 약학회지 7 Pages
대한약학회 약학회지 2012, Vol.56 No.3 173-179 (7 pages)
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Naringininduces Autophagy and Growth Inhibition by Down Regulating PI3K/Akt/mTOR Andactivating MAPK Pathway in AGS Cancer Cell
Suchismita Raha, Gyeong Eun Hong, Silvia Yumnam, Ho Jeong Lee, Venu Venkatarame Gowda Saralamma, Jeong Doo Heo, Sang Joon Lee, Gon Sup 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 춘계학술심포지움 136 209-210 (2 pages)
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Complete Genome of A Novel Phage KBNP 1315 that Infects Avian Pathogenic Escherichia coli and Functional Characterization of Its Lysis-cassette
Jae Wook Jung, Tae Hun Kim, Jung Seok Lee, Seong Bin Park, Seong Won Nho, Ki Sei Kim, Tae Hwan Kim, Jong Earn Yu, Se Pyeong Im, Si Won K 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 춘계학술심포지움 135 208-209 (2 pages)
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Isolation and characterization of the Citrobacter freundii phage EF1 from earthworm (Eisenia fetida)
Jun Heon Yeo, Jung Seok Lee, Se Pyeong Im, Jassy Mary Lazarte, Si Won Kim, Jae Wook Jung, Hong Jae Shin, Jung Yeol Bae, Ae Rin Lee, Jae s 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 293 352-353 (2 pages)
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Identification of Taylorella equigenitalis responsible for contagious equine metritis(CEM) in equine genital swabs from Korea inland Thoroughbred mares by Real-time polymerase chain reaction
Ji Yong Hwang, Chul Song Park, Gil Jae Cho 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 92 234-235 (2 pages)
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IntracellularTrafficking Modulation by Ginsenoside Rg3 Inhibits the Brucella abortus Uptake and Intracellular Survival within RAW 264.7Cells
Tran Xuan Ngoc Huy, Lauren Togonon Arayan, Alisha Wehdnesday Bernardo Reyes, Huynh Tan Hop, Suk Kim 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 91 233-234 (2 pages)
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Involvement of MAPK/NF-κB signal transduction pathways: Camelliajaponica mitigates inflammationand gastric ulcer
Rashedunnabi Aka, Weishun Tian, Anowarul Islam, In Shik Kim, Dongchoon Ahn, Hyun Jin Tae, Gi beum Kim, Byung Yong Park 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 247 344-345 (2 pages)
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MAPK/NF-κB targeting anti-inflammatory and gastroprotective activities of Rabdosia inflexa in vivo and in vitro
Rashedunnabi Aka, Weishun Tian, Anowarul Islam, In Shik Kim, Dong-choon Ahn, Hyun Jin Tae, Byung Yong Park 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 244 343-343 (1 pages)
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Single-factor-encoding mRNA mediate direct lineage reprogramming of human umbilical cord blood-derived mesenchymal stem cells into neural stem cells
Bo Eun Kim, Soon Won Choi, Ji Hee Shin, Myoung Geun Kook, Kyung Sun Kang 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 243 342-343 (2 pages)
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Naringin Induced Lysosomal Degradation and Mitochondrial Oxidative Stress Cross Talk Leads Autophagic Cell Death in Gastric CancerAGS Cells
Suchismita Raha, Ho Jeong Lee, Venu Venkatarame Gowda Saralamma, Seong Min Kim, Anjugam Paramanantham, Sang Eun Ha, Jeong Doo Heo, Sang 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 211 324-324 (1 pages)
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Cytoprotective effect of Sargassum honeri in micro dust exposed normal lung epithelial cell line MLE-12 cells: comparison with lung carcinoma cell line A549 cells
Kalahe hewage Iresha Nadeeka Madushani Herath, Jin-hee Cho, A-reum Kim, You jin Jeon, Young-heun Jee 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 210 323-324 (2 pages)
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Comparative aspects of microRNA expression in canine and human cancers
Kabiru Sahabi, Gayathri T. Selvarajah, Rasedee Abdullah, Yoke Kqueen Cheah, Geok Chin Tan 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 2호 2 162-171 (10 pages)
MicroRNAs (miRNAs) have important roles in all biological pathways in multicellular organisms. Over 1,400 human miRNAs have been identified, and many are conserved among vertebrates and invertebrates. Regulation of miRNA is the most common mode of post-transcriptional gene regulation. The miRNAs that are involved in the initiation and progression of cancers are termed oncomiRs and several of them have been identified in canine and human cancers. Similarly, several miRNAs have been reported to be... -
Tannic acid-mediated immune activation attenuates Brucella abortus infection in mice
Alisha W. B. Reyes, Huynh T. Hop, Lauren T. Arayan, Tran X. N. Huy, Wongi Min, Hu Jang Lee, Hong Hee Chang, Suk Kim 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 1호 8 51-57 (7 pages)
(MAPKs) (ERK 1/2 and p38α) phosphorylation were reduced in TA-treated cells compared with that in control cells. The mice were infected via an intraperitoneal route and were orally given TA or phosphate-buffered saline for 14 days. Spleen weights of the TA-treated and control mice were not different; however, splenic proliferation of B. abortus was significantly reduced in the TA-treated group. Immune response analysis showed that, compared with the control group, non-infected TA-treated mice... -
Inhibitory effect of red ginseng acidic polysaccharide from Korean red ginseng on phagocytic activity and intracellular replication of Brucella abortus in RAW 264.7 cells
Alisha Wehdnesday Bernardo Reyes, Hannah Leah Tadeja Simborio, Huynh Tan Hop, Lauren Togonon Arayan, Won Gi Min, Hu Jang Lee, Ma 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 3호 7 315-321 (7 pages)
of B. abortus-containing phagosomes with lysosome-associated membrane protein 1 (LAMP-1) were observed in RGAP-treated cells compared with the control. Overall, the results of this study suggest that RGAP can disrupt phagocytic activity of B. abortus via suppression of mitogen-activated protein kinases (MAPKs) signaling proteins ERK, JNK and p38 levels and inhibit intracellular replication of B. abortus by enhancing phagolysosome fusion, which may provide an alternative control of brucellosis. -
Aristolochia manshuriensis Kom ethyl acetate extract protects against high-fat diet-induced non-alcoholic steatohepatitis by regulating kinase phosphorylation in mouse
Dong Hoon Kwak, Ji-Su Kim, Kyu-Tae Chang, Young-Kug Choo 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 3호 3 279-287 (9 pages)
Aristolochia manshuriensis Kom (AMK) is an herb used as a traditional medicine; however, it causes side effects such as nephrotoxicity and carcinogenicity. Nevertheless, AMK can be applied in specific ways medicinally, including via ingestion of low doses for short periods of time. Non-alcoholic steatohepatitis (NASH) induced the hepatocyte injury and inflammation. The protective effects of AMK against NASH are unclear; therefore, in this study, the protective effects of AMK ethyl acetate... -
Gap junction blockage promotes cadmium-induced apoptosis in BRL 3A derived from Buffalo rat liver cells
Di Hu, Hui Zou, Tao Han, Junze Xie, Nannan Dai, Liling Zhuo, Jianhong Gu, Jianchun Bian, Yan Yuan, Xuezhong Liu, Zongping Liu 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 1호 8 63-70 (8 pages)
Gap junctions mediate direct communication between cells; however, toxicological cascade triggered by nonessential metals can abrogate cellular signaling mediated by gap junctions. Although cadmium (Cd) is known to induce apoptosis in organs and tissues, the mechanisms that underlie gap junction activity in Cd-induced apoptosis in BRL 3A rat liver cells has yet to be established. In this study, we showed that Cd treatment decreased the cell index (a measure of cellular electrical impedance) in...
