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LPS Increases 5-LO Expression on Monocytes via an Activation of Akt-Sp1/NF-κB Pathways
SeungJinLee, KyoWonSeo, ChiDaeKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.3 11 263-268 (6 pages)
pivotal role in the progression of atherosclerosis. Therefore, this study investigated the molecular mechanisms involved in 5-LO expression on monocytes induced by LPS. Stimulation of THP-1 monocytes with LPS (0∼3 μg/ml) increased 5-LO promoter activity and 5-LO protein expression in a concentration-dependent manner. LPS-induced 5-LO expression was blocked by pharmacological inhibition of the Akt pathway, but not by inhibitors of MAPK pathways including the ERK, JNK, and p38 MAPK pathways. In... -
Arabinogalactan-type Polysaccharides (APS) from Cordyceps militaris Grown on Germinated Soybeans (GSC) Induces Innate Immune Activity of THP-1 Monocytes through Promoting Their Macrophage Differentiation and Macrophage Activity
Park. Dong Ki, Hayashi. Toshimitsu, Park. Hye-Jin 한국식품과학회 Food science and biotechnology 6 Pages
한국식품과학회 Food science and biotechnology 2012, Vol.21 No.5 1501-1506 (6 pages)
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Isolation of Monocytes with High Purity and Yield from Peripheral Blood Mononuclear Cells by Flotation Density Gradient Centrifugation
배재호, 손철훈, 박유수, 김동완, 김선희, 강치덕, Bae. Jae-Ho, Son. Cheol-Hun, Park. You-Soo, Kim. Dong-Wan, Kim. Sun-Hee, Kang. Chi-Dug 한국생명과학회 생명과학회지 7 Pages
한국생명과학회 생명과학회지 2009, Vol.19 No.6 728-734 (7 pages)
본 연구에서는, PBMC로부터 고순도 및 고수율의 단세포를 분리하기 위해 Histopaque 용액의 density 및 osmolarity를 PBS와 NaCI 용액으로 1.072 g/ml 및 335 mOsm로 조절하여 간단하고 경제적인 방법인 부유밀도구배 원심분리법을 개발하였다. 위와 같이 조절된 Histopaue 용액을 사용하여 부유밀도구배 원심분리를 시행한 결과 단세포는 Top층에서 가장 많이 회수되었다. 회수된 단세포의 순도는 71.44${sim}$82.38%의 범위를 나타내었고 평균 74.75${pm}$3.84% 이었다. 또한, 수율은 21.02${sim}$53.63%의 범위를 나타내어 평균... -
KR-31543 reduces the production of proinflammatory molecules in human endothelial cells and monocytes and attenuates atherosclerosis in mouse model
Choi. Jae-Hoon, Yoo. Ji-Young, Kim. Sun-Ok, Yoo. Sung-Eun, Oh. Goo Taeg 생화학분자생물학회 Experimental & molecular medicine : EMM 7 Pages
생화학분자생물학회 Experimental & molecular medicine : EMM 2012, Vol.44 No.12 733-739 (7 pages)
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In vitro cytotoxicity of four calcium silicate-based endodontic cements on human monocytes, a colorimetric MTT assay
Khedmat. Sedigheh, Dehghan. Somayyeh, Hadjati. Jamshid, Masoumi. Farimah, Nekoofar. Mohammad Hossein, Dummer. Paul Michael Howell 대한치과보존학회 RDE : Restorative dentistry & endodontics 6 Pages
대한치과보존학회 RDE : Restorative dentistry & endodontics 2014, Vol.39 No.3 149-154 (6 pages)
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The House Dust Mite Allergen, Dermatophagoides pteronyssinus Suppresses the Chemotactic Activity of Human Monocytes
Lee. Ji-Sook, Yang. Eun Ju, Kim. In Sik 대한의생명과학회 Journal of experimental & biomedical sciences 3 Pages
대한의생명과학회 Journal of experimental & biomedical sciences 2012, Vol.18 No.4 435-437 (3 pages)
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Functional Activation of Macrophages, Monocytes and Splenic Lymphocytes by Polysaccharide Fraction from Tricholoma matsutake
Byeon. Se-Eun, Lee. Jae-Hwi, Lee. Eun-Ji, Lee. Song-Yi, Hong. Eock-Kee, Kim. Young-Eon, Cho. Jae-Youl 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 8 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2009, Vol.32 No.11 1565-1572 (8 pages)
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Effects of Mitochondrial Inhibitors on Cell Viability in U937 Monocytes Under Glucose Deprivation
Han. Mi-Jin, Im. Dong-Soon 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 9 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2008, Vol.31 No.6 749-757 (9 pages)
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Anti-inflammatory Mechanisms of Apigenin: Inhibition of Cyclooxygenase-2 Expression, Adhesion of Monocytes to Human Umbilical Vein Endothelial Cells, and Expression of Cellular Adhesion Molecules
Lee. Je-Hyuk, Zhou. Hong-Yu, Cho. So-Yean, Kim. Yeong-Shik, Lee. Yong-Soo, Jeong. Choon-Sik 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 10 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2007, Vol.30 No.10 1318-1327 (10 pages)
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In Vitro Stimulation of Murine Peritoneal Monocytes Induced by Alginates
Pasquali. Paolo, Zalcman. Amy, Murtas. Susanna, Adone. Rosanna, Brambilla. Gianfranco, Marianelli. Cinzia, Cagiola. Monica, Ciuchini. F 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 6 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2005, Vol.28 No.8 936-941 (6 pages)
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Role of Mitogen-Activated Protein Kinase Pathways in the Production of TNF-$alpha$, IL-10, and MCP-1 by Mycobacterium tuberculosis H37Rv-Infected Human Blood Monocytes
Song. Chang-Hwa, Lee. Ji-Sook, Lee. So-Hyun, Lim. Jae-Hyun, Lee. Kil-Soo, Jung. Saet-Byel, Kim. Su-Young, Kim. Hwa-Jung, Park. Jeong-Kyu 대한미생물학회 Journal of bacteriology and virology : JBV 11 Pages
대한미생물학회 Journal of bacteriology and virology : JBV 2003, Vol.33 No.2 139-149 (11 pages)
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Global Transcriptional Analysis Reveals Upregulation of NF-${kappa}B$-responsive and Interferon-stimulated Genes in Monocytes by Treponema lecithinolyticum Major Surface Protein
Lee. Sung-Hoon, Lee. Hae-Ri, Jun. Hye-Kyoung, Choi. Bong-Kyu 대한구강생물학회 International journal of oral biology : official journal of the Korean Academy of Oral Biology and t 11 Pages
대한구강생물학회 International journal of oral biology : official journal of the Korean Academy of Oral Biology and t 2011, Vol.36 No.2 91-101 (11 pages)
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Ginsenoside fractions regulate the action of monocytes and their differentiation into dendritic cells
Lee. Yeo Jin, Son. Young Min, Gu. Min Jeong, Song. Ki-Duk, Park. Sung-Moo, Song. Hyo Jin, Kang. Jae Sung, Woo. Jong Soo, Jung. Jee Hyung 고려인삼학회 Journal of ginseng research 9 Pages
고려인삼학회 Journal of ginseng research 2015, Vol.39 No.1 29-37 (9 pages)
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Effectivesuppression of PRRSV replicating in monocyte- derived macrophages byCD8-depleted PBMC
Sang Ho Cha, Amanda L. Grimm, Joanna Rzepka, Dharani Ajithdoss, Grace Chung, William C, Davis, Jae Young Song, In soo Cho, Jienny Lee, Cha 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 255 474-475 (2 pages)
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Tlymphocytes induced by single PRRSV strain efficiently recognize epitopesprocessed from highly diverse PRRSV strains
Amanda L. Grimm, Grace Chung, Sang Ho Cha, Kyoung Jin Yoon, Joel Sparks, Locke A. Karriker, Chung won J. Chung 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 210 448-448 (1 pages)
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Overview of Ebola Virus Infection
Ji yeon Kim, Won jun Bae, Sung mo Je, Seung Hyeok Seok, Eung Soo Hwang 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 48 275-275 (1 pages)
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Use of animal models in the development of radioprotector
Joong Sun Kim 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 18 115-115 (1 pages)
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Development of Biomarkers Utilizing Variable Lymphocyte Receptors (VLRs) of Inshore Hagfish (Eptatretus burgeri) against Avian Influenza Virus
Se pyeong Im, Tae sung Jung, Jae sung Kim, Jung seok Lee, Si won Kiim, Tae hoon Kim, Jae wook Jung 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 춘계학술심포지움 42 158-159 (2 pages)
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Genetic engineering of a temperate phage-based delivery system for CRISPR/Cas9 antimicrobials against Staphylococcus aureus
Bo-youn Moon, Joo Youn Park, Justin A. Thornton, Juw Won Park, Yong Ho Park, Kyung Ki Lee, Seong Hee Kim, Yeon Hee Kim, Dong Chan Moon, B 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 114 249-250 (2 pages)
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Effect of ivermectin on prevention of Theileria Infection and hemolytic anemiain grazing cattle
Jeong Byoung Chae, Su Hee Kim, Suck Han Jeong, Jin Hee Kang, Do Hyeon Yu, Kyoung Seong Choi, Hyeon Cheol Kim, Bae Keun Park, Joon Seok C 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 310 378-379 (2 pages)
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Polioencephalomalacia in cattle, 2012~2016
Ji Youl Jung, Kyung-hyun Lee, Byung-Jae So, Eun-jin Choi 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 283 364-364 (1 pages)
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Hepatobiliary diseases in buffalo (Bubalus bubalis)
Arafat Khalphallah, Nasr-Eldin M. Aref, Ashraf M. Abu-Seida, Enas Elmeligy, Sara A. Bayoumi, Al-lethie A. Al-lethie, Doaa Salman 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 4호 10 543-549 (7 pages)
This study describes ultrasonographic observations of five hepatobiliary diseases in buffalo (Bubalus bubalis). Fifty buffalo, including 20 clinically normal and 30 hepatobiliary diseased buffalo were enrolled in the study. Complete clinical, radiographic and ultrasonographic examinations and laboratory analyses were conducted. Focal parenchymal lesions including liver abscess (n = 12) and hepatic cyst (n = 6), diffuse parenchymal lesion (hepatobiliary cirrhosis, n = 5) and obstruction of... -
A Salmonella Typhi ghost induced by the E gene of phage X174 stimulates dendritic cells and efficiently activates the adaptive immune response
Gayeon Won, Seong Kug Eo, Sang-Youel Park, Jin Hur, John Hwa Lee 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 4호 9 536-542 (7 pages)
Previously, we genetically engineered a Salmonella Typhi bacterial ghost (STG) as a novel inactivated vaccine candidate against typhoid fever. The underlying mechanism employed by the ghost in stimulating the adaptive immune response remains to be investigated. In this study, we aimed to evaluate the immunostimulatory effect of STG on mouse bone marrow-derived dendritic cells (BMDCs) and its activation of the adaptive immune response in vitro. Immature BMDCs were stimulated with STG, which... -
Marek’s disease vaccine activates chicken macrophages
Dan Wang, Shuhong Sun, Mohammad Heidari 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 3호 7 375-383 (9 pages)
To provide insights into the role of innate immune responses in vaccine-mediated protection, we investigated the effect of Marek’s disease (MD) vaccine, CVI988/Rispens, on the expression patterns of selected genes associated with activation of macrophages in MD-resistant and MD-susceptible chicken lines. Upregulation of interferon , interleukin (IL)-1, IL-8, and IL-12 at different days post-inoculation (dpi) revealed activation of macrophages in both chicken lines. A strong... -
Association between endotoxin levels in dust from indoor swine housing environments and the immune responses of pigs
Katharine Roque, Kyung Min Shin, Ji Hoon Jo, Gyeong Dong Lim, Eun Seob Song, So Jung Shin, Ravi Gautam, Jae Hee Lee, Yeon Gyeong Kim, Ah 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 3호 2 331-338 (8 pages)
Indoor animal husbandry environments are inevitably contaminated with endotoxins. Endotoxin exposure is associated with various inflammatory illnesses in animals. This cross-sectional study evaluated the relationship between the degree of endotoxin exposure and the cellular and humoral immune profiles of fattening pigs. Blood samples were taken from the jugular vein of 47 pigs from ten pig farms in Korea. Whole blood cell counts and plasma immunoglobulin (Ig) classes were determined.... -
Haemoproteus in barn and collared scops owls from Thailand
Chaleow Salakij, Pornchai Pornpanom, Preeda Lertwatcharasarakul, Chaiyan Kasorndorkbua, Jarernsak Salakij 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 2호 14 280-289 (10 pages)
The barn owl (BO) and the collared scops owl (CSO) are common nocturnal raptors throughout Thailand. Blood samples from 23 adult BOs and 14 CSOs were collected and processed for complete blood cell counts and parasite morphological examinations. Two Haemoproteus-positive samples were processed for ultrastructural observation. Polymerase chain reaction (PCR) analysis for a partial cytochrome b gene (cytb) from Haemoproteus was performed in all samples. Haemoproteus presence detected by light... -
Tannic acid-mediated immune activation attenuates Brucella abortus infection in mice
Alisha W. B. Reyes, Huynh T. Hop, Lauren T. Arayan, Tran X. N. Huy, Wongi Min, Hu Jang Lee, Hong Hee Chang, Suk Kim 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 1호 8 51-57 (7 pages)
Brucellosis is an emerging infectious disease affecting humans and animals. In this study, we investigated the in vitro and in vivo effects of tannic acid (TA) against Brucella abortus infection. After infection, F-actin polymerization and mitogen-activated protein kinases (MAPKs) (ERK 1/2 and p38α) phosphorylation were reduced in TA-treated cells compared with that in control cells. The mice were infected via an intraperitoneal route and were orally given TA or phosphate-buffered saline for 14...


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