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Effect of Horizontal Resistance at Slab Bottom on Behavior of Concrete Slabs-on-Grade under Vertical Loads
심재수, 김성민, Shim. Jae-Soo, Kim. Seong-Min 한국도로학회 한국도로학회논문집 10 Pages
한국도로학회 한국도로학회논문집 2005, Vol.7 No.4 141-150 (10 pages)
지반위에 놓인 콘크리트 슬래브가 수직 하중을 받을 때 지반의 전단저항과 슬래브 하부와 지반과의 마찰 등에 의해 생기는 슬래브 하부의 수평저항을 고려하여 지반위에 놓인 콘크리트 슬래브의 거동을 분석하였다. 슬래브 하부의 수평 저항을 고려하기 위한 해석 공식을 유도하였고 퓨리에변환을 이용한 변환영역에서 이러한 공식의 해를 구하였다. 또한 판요소와 쉘요소를 이용한 유한요소법에 의한 모델을 개발하여 수치 해석 결과도 도출하였다. 이러한 해석 공식과 수치해석 모델을 이용한 해석 결과를 비교 분석하였고 매우 비슷한... -
The characteristics of the multi-span suspension bridge with double main cables in the vertical plane
Zhang. Li-Wen, Xiao. Ru-Cheng, Jiang. Yang, Chai. Sheng-Bo 테크노프레스 Structural engineering and mechanics : An international journal 21 Pages
테크노프레스 Structural engineering and mechanics : An international journal 2012, Vol.42 No.3 291-311 (21 pages)
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Effects of foot pressure using the elastic band with rings during sit-to-stand in persons with stroke
Young-In Hwang, Ki-Song Kim 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2017, 제 6권 제 4호 1 159-163 (5 pages)
Objective: Persons with stroke have a tendency to exhibit asymmetric weight-bearing during sit-to-stand because due to the attempt to support themselves with the non-paretic foot. However, there are few devices that can assist with sit-to-stand (STS) performance. This study was designed to investigate the use of the elastic band with rings (EBR) in improving weight-bearing effectively in persons with stroke during STS training. Design: Cross-sectional study. Methods: Thirteen stroke survivors... -
The effects of water-based exercise on postural control in children with spastic cerebral palsy
Kyung Ho Kim, Hwa Kyung Shin 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2017, 제 6권 제 2호 5 77-82 (6 pages)
Objective: Swimming and water-based exercise (WE) programs can provide vigorous physical activity in a fun and a motivating environment. The properties of water, may make it easier for children with cerebral palsy (CP) to move and to participate in an WE program. The aims of this study was to evaluate the effect of WEs on postural control in children with spastic CP. Design: Quasi-experimental design (one group pretest-posttest design). Methods: Twenty preschoolers with spastic CP participated... -
Musculoskeletal diseases of heavy industrial workers
Hyun-jin Baek, Sun-hae Song, Dong-geon Lee, Seung-hyeon Pyo, Doo-chul Shin, Gyu-chang Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2017, 제 6권 제 2호 4 71-76 (6 pages)
Objective: The purpose of this study was to investigate the musculoskeletal diseases (MSDs) that occur in heavy industrial workers according to the occupational category, prevalence, environment, and number of physical therapy visits. Design: Retrospective cohort study. Methods: For this study, data was collected of workers who were engaged in heavy industry in Korea and who visited the company physicians and received physical therapy in 2016. Data was collected from 855 subjects and was... -
Effect of changes in head postures during use of laptops on muscle activity of the neck and trunk
Seul-gi Lee, Ye-seb Lee, Yi-jung Chung 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2017, 제 6권 제 1호 6 33-38 (6 pages)
at their knees while having their external auditory meatus, acromion, and greater trochanter vertical to the ground. For the natural head posture, they practiced typing while balancing their posture between extension and flexion of the cervical vertebrae by themselves without any guidelines. While a forward head posture was created by having their heads face the front horizontal to the rope hanging from the ceiling, they practiced typing with their external auditory meatus located in the place... -
Effects of vibration resistance exercise on strength, range of motion, function, pain and quality of life in persons with tennis elbow
Jong-Hun Lim, Won-Seob Shin 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 4호 1 163-169 (7 pages)
Objective: The purpose of this study was to investigate the effects of vibration resistance exercise (VRE) in patients with tennis elbow on strength, range of motion (ROM), function, pain and quality of life (QOL). Design: Randomized controlled trial. Methods: Twenty-seven participants were randomly assigned to either the VRE group (n=9), weight resistance exercise (WRE) group (n=9) or control group (n=9). Each group underwent hot compress for 15 minutes and electrotherapy for 15 minutes. The... -
Reliability and validity of a personal computer based muscle viewer for measuring upper trapezius and transverses abdominis muscle thickness
Ju-Ri Jeong, Ju Hee Han, Ji-Eun Cho, Wan-hee Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 3호 8 155-161 (7 pages)
Objective: This study aimed to investigate the reliability and validity of a personal computer-based muscle viewer (PC-BMW) compared with that of a portable ultrasound (P-US) for measuring upper trapezius (UT) and transversus abdominis (TrA) muscle thickness at rest and during contraction. Design: Observational inter-rater reliability study. Methods: Fifty-five healthy participants (25 men, 30 women) participated in this study. PC-BMW and P-US were randomly measured at the UT and TrA muscles.... -
The effect of applying a head-weight device on cervical angle and pain of neck muscles
Jin-Hong Kim, Jong-Gun Kim, Kwang-Sun Do, Jong-eun Yim 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 2호 8 101-105 (5 pages)
Objective: The purpose of this study was to measure the change in pain threshold of levator scapular muscle, carniovertebral angle, and head position angle when applying a head-weight device on healthy adult. Design: Cross-sectional study. Methods: This study was conducted with 21 healthy adult male and female who voluntarily agreed to participate in this study after being informed of the purpose and method of this study. After measuring the cervical angle and pain threshold of levator scapular... -
Electromyographic analysis according to shoe weight during ambulation
Eun-sang Lee, Byung-hoon Lee, Ju-chul Cho, Yong-woo Lee, Seung-won Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2015, 제 4권 제 2호 9 115-120 (6 pages)
Objective: To examine the effects of different shoe weights on lower leg muscle fatigue when walking by electromyographic(EMG) analysis due to the most effective weight for loading not being established. Design: Cross-sectional study. Methods: Thirty healthy university students (15 male, 15 female) were enrolled and randomly assigned into three conditions, which included wearing athletic shoes with an addition of 300 g, 500 g, and 1,000 g weights respectively. Prior to walking, all subjects were... -
The effect of whole body vibration training on postural sway in patients with spinal cord injury
Yasuyoshi Asakawa, Myung-Mo Lee, Chang-Ho Song 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2013, 제 2권 제 2호 2 70-74 (5 pages)
Objective: The aim of this study was to determine the impact of the application of whole body vibration training (WBV) on the balance ability of patients with an American Spinal Injury Association (ASIA) type C or D spinal cord injury. Design: Randomized controlled trial. Methods: Twelve patients with spinal cord injury were enrolled in this study. The participants were randomized to an experimental group (n=6) or control group (n=6). The subjects in the experimental group received WBV exercise... -
Changes in hoof kinetics and kinematics at walk in response to hoof trimming
Babak Faramarzi, An Nguyen, Fanglong Dong 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 4호 12 557-562 (6 pages)
when p < 0.05. Vertical force (p = 0.026) and contact pressure (p = 0.006) increased after trimming. Stance-phase duration (p = 0.006), swing-phase duration (p = .023), and gait-cycle duration (p = 0.007) decreased significantly post-trimming. The observed changes in kinetic and kinematic parameters were related to hoof trimming. The reported results underline the importance of farriery practice and its effect on hoof biomechanics, which should be considered by both farriers and veterinarians. -
Phenotypic and genotypic analyses of an attenuated porcine reproductive and respiratory syndrome virus strain after serial passages in cultured porcine alveolar macrophages
Seung-Chul Lee, Sunhee Lee, Gun-Woo Yoo, Hwan-Won Choi, Yun-Hee Noh, Chang Eon Park, Jae-Ho Shin, In-Joong Yoon, Shien-Young Kang4, Chang 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 3호 5 358-367 (10 pages)
The porcine reproductive and respiratory syndrome virus (PRRSV) is a globally ubiquitous swine viral pathogen that causes major economic losses worldwide. We previously reported an over-attenuated phenotype of cell-adapted PRRSV strain CA-2-P100 in vivo. In the present study, CA-2-P100 was serially propagated in cultured porcine alveolar macrophage (PAM) cells for up to 20 passages to obtain the derivative strain CA-2-MP120. Animal inoculation studies revealed that both CA-2-P100 and CA-2-MP120... -
Hepatitis E virus as an emerging zoonotic pathogen
Woo-Jung Park, Byung-Joo Park, Hee-Seop Ahn, Joong-Bok Lee, Seung-Yong Park, Chang-Seon Song, Sang-Won Lee, Han-Sang Yoo, In-Soo 대한수의학회 Journal of Veterinary Science 11 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 1호 1 1-11 (11 pages)
Hepatitis E outbreaks are a serious public health concern in developing countries. The disease causes acute infections, primarily in young adults. The mortality rate is approximately 2%; however, it can exceed 20% in pregnant women in some regions in India. The causative agent, hepatitis E virus (HEV), has been isolated from several animal species, including pigs. HEV genotypes 3 and 4 have been isolated from both humans and animals, and are recognized as zoonotic pathogens. Seroprevalence... -
Development and clinical evaluation of a rapid diagnostic kit for feline leukemia virus infection
Won-Shik Kim, Chom-Kyu Chong, Hak-Yong Kim, Gyu-Cheol Lee, Wooseog Jeong, Dong-Jun An, Hye-Young Jeoung, Jae-In Lee, Young-Ki Le 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 1호 10 91-97 (7 pages)
Feline leukemia virus (FeLV) causes a range of neoplastic and degenerative diseases in cats. To obtain a more sensitive and convenient diagnosis of the disease, we prepared monoclonal antibodies specific for the FeLV p27 to develop a rapid diagnostic test with enhanced sensitivity and specificity. Among these antibodies, we identified two clones (hybridomas 8F8B5 and 8G7D1) that specifically bound to FeLV and were very suitable for a diagnostic kit. The affinity constants for 8F8B5 and 8G7D1... -
An overview of calf diarrhea - infectious etiology, diagnosis, and intervention
Yong-il Cho, Kyoung-Jin Yoon* 대한수의학회 Journal of Veterinary Science 17 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 1호 1 1-17 (17 pages)
Calf diarrhea is a commonly reported disease in young animals, and still a major cause of productivity and economic loss to cattle producers worldwide. In the report of the 2007 National Animal Health Monitoring System for U.S. dairy, half of the deaths among unweaned calves was attributed to diarrhea. Multiple pathogens are known or postulated to cause or contribute to calf diarrhea development. Other factors including both the environment and management practices influence disease severity or... -
The critical time of avian leukosis virus subgroup J-mediated immunosuppression during early stage infection in specific pathogen-free chickens
Feng Wang, Xiaowei Wang, Hongbo Chen, Jianzhu Liu, Ziqiang Cheng* 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2011, 제 12권 제 3호 6 235-241 (7 pages)
The critical time of avian leukosis virus subgroup J (ALV-J)-mediated immunosuppression was determined by body weight, relative immune organ weight, histopathology, and presence of group specific antigen and antibodies in specific pathogen-free (SPF) chickens. CD4 and CD8 cell activity in the spleen, total and differential leukocyte counts in blood, and viral RNA levels in spleen were measured. Significant growth suppression was observed in the two ALV-J-infected groups. A strong immune response... -
Comparison of the age-related porcine endogenous retrovirus (PERV) expression using duplex RT-PCR
Hyoung Joon Moon, Hye Kwon Kim, Seong Jun Park, Chul Seung Lee, Dae Sub Song, Bo Kyu Kang, Bong Kyun Park* 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2009, 제 10권 제 4호 7 317-322 (6 pages)
Porcine endogenous retroviruses (PERVs) are members of family Retroviridae, genus Gamma retrovirus, and transmitted by both horizontally and vertically like other endogenous retroviruses (ERVs). PERV was initially described in the 1970s having inserted its gene in the host genome of different pig breeds, and three classes, PERV-A, PERV-B, and PERV-C are known. The therapeutic use of living cells, tissues, and organs from animals called xenotransplantation might relieve the limited supply of... -
Contribution of the xenograft bone plate-screw system in lumbar transpedicular stabilization of dogs: an in-vitro study
Hakan Salci*, Sani Sarigul, Seref Dogan, Huseyin Lekesiz, Resat Ozcan, O. Sacit Gorgul, Kaya Aksoy 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 2호 10 193-196 (4 pages)
We performed biomechanical comparison of a xenograft bone plate-screw (XBPS) system for achieving cadaveric lumbar transpedicular stabilization (TS) in dogs. Twenty dogs' cadaveric L2-4 lumbar specimens were harvested and their muscles were removed, but the discs and ligaments were left intact. These specimens were separated to four groups: the L2-4 intact group as control (group I, n = 5), the L3 laminectomy and bilateral facetectomy group (LBF) (group II, n = 5), the LBF plus TS with metal... -
The effects of cyclophosphamide treatment on the pathogenesis of subgroup J avian leukosis virus (ALV-J) infection in broiler chickens with Marek's disease virus exposure
Yongbaek Kim, Thomas P. Brown and Mary J. Pantin-Jackwood 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2004, 제 5권 제 1호 7 49-58 (10 pages)
viremia, in the CY treated group. No neoplastic foci consistent with ALVJ infection were observed in any of the experimental chickens. The frequency and intensity of viral antigen expression determined by immunohistochemistry was significantly higher in tissues from CY treated birds than those of PBS treated chickens at 3 weeks post-infection. This study showed that B cell specific immunosuppression with CY treatment in chickens resulted in increase in viremia and viral antigen load in tissues. -
Effects of cyclosporin A treatment on the pathogenesis of avian leukosis virus subgroup J infection in broiler chickens with Marek’s disease virus exposure
Yongbaek Kim, Thomas P. Brown, Mary J. Pantin-Jackwood 대한수의학회 Journal of Veterinary Science 11 Pages
대한수의학회 Journal of Veterinary Science 2003, 제 4권 제 3호 8 245-255 (11 pages)
In this study, we investigated the effects of T-cell suppression on the pathogenesis of subgroup J avian leukosis virus (ALV-J). Chickens were treated with cyclosporin A (CSP) 50 mg/Kg body weight or a corresponding volume of olive oil per every three days after hatching until the end of experiment. Some of the chickens from each treatment group were infected with an isolate of ALV-J, ADOL-7501, at 2 weeks of age. The effects of viral infection were compared to uninfected birds in same treatment... -
Cytokine expression pattern in milk somatic cells of subclinical mastitis-affected cattle analyzed by real time PCR
Vaibhav D Bhatt , Prasad S Khade , Sagar B Tarate , Ajai K Tripathi , Dev S Nauriyal , Dharamshi N Rank , Anju P Kunjadia 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 8 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2012, 제 52권 제 4호 3 231-238 (8 pages)
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Effects of thermoforming on the physical and mechanical properties of thermoplastic materials for transparent orthodontic aligners
Jeong-Hyun Ryu, Jae-Sung Kwon, Heng Bo Jiang, Jung-Yul Cha, Kwang-Mahn Kim 대한치과교정학회 The Korean Journal of Orthodontics 10 Pages
대한치과교정학회 The Korean Journal of Orthodontics 2018, 제 48권 제 5호 5 316-325 (10 pages)
Objective: The aim of this systematic multiscale analysis was to evaluate the effects of thermoforming on the physical and mechanical properties of thermoplastic materials used to fabricate transparent orthodontic aligners (TOAs). Methods: Specimens were fabricated using four types of thermoplastic materials with different thicknesses under a thermal vacuum. Transparency, water absorption and solubility, surface hardness, and the results of three-point bending and tensile tests were evaluated... -
Displacement and stress distribution of the maxillofacial complex during maxillary protraction using palatal plates
Jusuk Eom, Mohamed Bayome, Jae Hyun Park, Hee Jin Lim, Yoon-Ah Kook, Seong Ho Han 대한치과교정학회 The Korean Journal of Orthodontics 12 Pages
대한치과교정학회 The Korean Journal of Orthodontics 2018, 제 48권 제 5호 4 304-315 (12 pages)
Objective: The purpose of this study was to analyze initial displacement and stress distribution of the maxillofacial complex during dentoskeletal maxillary protraction with various appliance designs placed on the palatal region by using three-dimensional finite element analysis. Methods: Six models of maxillary protraction were developed: conventional facemask (Type A), facemask with dentoskeletal hybrid anchorage (Type B), facemask with a palatal plate (Type C), intraoral traction using a... -
Histomorphometric evaluation of the bone surrounding orthodontic miniscrews according to their adjacent root proximity
Hyun-Ju Oh, Jung-Yul Cha, Hyung-Seog Yu, Chung-Ju Hwang 대한치과교정학회 The Korean Journal of Orthodontics 9 Pages
대한치과교정학회 The Korean Journal of Orthodontics 2018, 제 48권 제 5호 2 283-291 (9 pages)
Objective: This study was conducted to perform histomorphometric evaluations of the bone surrounding orthodontic miniscrews according to their proximity to the adjacent tooth roots in the posterior mandible of beagle dogs. Methods: Four male beagle dogs were used for this study. Six orthodontic miniscrews were placed in the interradicular spaces in the posterior mandible of each dog (n = 24). The implanted miniscrews were classified into no loading, immediate loading, and delayed loading groups... -
Report on a case treated with lingual multibracket appliance
Hee-Moon Kyung 대한치과교정학회 The Korean Journal of Orthodontics 11 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1996, 제 26권 제 6호 6 705-715 (11 pages)
The lingual multibracket appliance was developed to overcome the unesthetic nature of traditional fixed orthodontic labial appliances; however, treatment with this appliance was regarded as very difficult as well as a time-consuming. Recently, these problems have been reduced because of advances in lingual bracket systems, improved indirect bonding technique and the development of more flexible wires. There has been a marked increase in the number of adults desiring orthodontic treatment over... -
The effects of posterior retraction on the displacement of the maxilla
Bo-Yeong Yoo, Jong-Chul Kim 대한치과교정학회 The Korean Journal of Orthodontics 13 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1996, 제 26권 제 6호 5 691-703 (13 pages)
Three-dimensional finite element model was made from adult skull to find desirable direction of retraction force to treat skeletal class II malocclusion. The retraction force of 400g was applied to the first molar. The direction of the force application was 23° downward, parallel, 23° upward and 45` upward to the occlusal plane. The stress distribution and the displacement within the maxilla were analyzed by three-dimensional finite element method. The findings obtained were as follows: 1.... -
작업기억 검사도구 개발에 관한 소고
손태권, 이광호, 성창근 한국교원대학교 뇌기반교육연구소 Brain, Digital, & Learning 24 Pages
한국교원대학교 뇌기반교육연구소 Brain, Digital, & Learning 2019, 제 9권 제 3호 4 139-162 (24 pages)
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Repaglinide, but Not Nateglinide Administered Supraspinally and Spinally Exerts an Anti-Diabetic Action in D-Glucose Fed and Streptozotocin-Treated Mouse Models
Yun-BeomSim, Soo-HyunPark, Yu-JungKang, Sung-SuKim, Chea-HaKim, Su-JinKim, Su-MinLim, Jun-SubJung, Ohk-HyunRyu, Moon-GiChoi, Hong-WonSuh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.6 3 493-498 (6 pages)
We have recently demonstrated that some anti-diabetic drugs such as biguanide and thizolidi-nediones administered centrally modulate the blood glucose level, suggesting that orally administered anti-diabetic drugs may modulate the blood glucose level by acting on central nervous system. The present study was designed to explore the possible action of another class of anti-diabetic drugs, glinidies, administered centrally on the blood glucose level in ICR mice. Mice were administered... -
High K+-Induced Relaxation by Nitric Oxide in Human Gastric Fundus
DaeHoonKim, YoungChulKim, WoongChoi, Hyo-YoungYun, RohyunSung, HunSikKim, HeonKim, RaYoungYoo, Seon-MeePark6, SeiJinYun6, Young-JinSong, We 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.5 2 297-303 (7 pages)
This study was designed to elucidate high K+-induced relaxation in the human gastric fundus. Circular smooth muscle from the human gastric fundus greater curvature showed stretch-dependent high K+ (50 mM)-induced contractions. However, longitudinal smooth muscle produced stretch-dependent high K+-induced relaxation. We investigated several relaxation mechanisms to understand the reason for the discrepancy. Protein kinase inhibitors such as KT 5823 (1 ՌM) and KT 5720 (1 ՌM) which... -
A Computational Model of Cytosolic and Mitochondrial [Ca2+] in Paced Rat Ventricular Myocytes
JaeBoumYoum, SeongWooChoi, ChangHanJang, HyoungKyuKim, ChaeHunLeem, NariKim, JinHan 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 23 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.4 5 217-239 (23 pages)
We carried out a series of experiment demonstrating the role of mitochondria in the cytosolic and mitochondrial Ca2+ transients and compared the results with those from computer simulation. In rat ventricular myocytes, increasing the rate of stimulation (1∼3 Hz) made both the diastolic and systolic [Ca2+] bigger in mitochondria as well as in cytosol. As L-type Ca2+ channel has key influence on the amplitude of Ca2+-induced Ca2+ release, the relation between stimulus frequency and the... -
Polyphenols of Rubus coreanum Inhibit Catecholamine Secretion from the Perfused Adrenal Medulla of SHRs
Byung-SikYu, Duck-MiNa, Mi-YoungKang, Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.6 17 517-526 (10 pages)
The present study was attempted to investigate whether polyphenolic compounds isolated from wine, which is brewed from Rubus coreanum Miquel (PCRC), may affect the release of catecholamines (CA) from the isolated perfused adrenal medulla of the spontaneously hypertensive rats (SHRs), and to establish its mechanism of action. PCRC (20∼180Ռg/ml) perfused into an adrenal vein for 90 min relatively dose-dependently inhibited the CA secretory responses to ACh (5.32 mM), high K+ (56 mM), DMPP... -
Provinol Inhibits Catecholamine Secretion from the Rat Adrenal Medulla
Jung-HeeLee, Yu-SeungSeo, Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.3 14 229-239 (11 pages)
The aim of the present study was to examine the effect of provinol, which is a mixture of polyphenolic compounds from red wine, on the secretion of catecholamines (CA) from isolated perfused rat adrenal medulla, and to elucidate its mechanism of action. Provinol (0.3∼3Ռg/ml) perfused into an adrenal vein for 90 min dose- and time-dependently inhibited the CA secretory responses evoked by ACh (5.32 mM), high K+ (a direct membrane-depolarizer, 56 mM), DMPP (a selective neuronal nicotinic... -
Forskolin Changes the Relationship between Cytosolic Ca2+ and Contraction in Guinea Pig Ileum
KoonHeeHan, GapJinCheon, DongSooYeon, SeongChunKwon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.3 8 189-194 (6 pages)
This study was designed to clarify the mechanism of the inhibitory effect of forskolin on contraction, cytosolic Ca2+ level ([Ca2+]i), and Ca2+ sensitivity in guinea pig ileum. Forskolin (0.1 nM∼10ՌM) inhibited high K+ (25 mM and 40 mM)- or histamine (3ՌM)-evoked contractions in a concentration- dependent manner. Histamine-evoked contractions were more sensitive to forskolin than high K+- evoked contractions. Spontaneous changes in [Ca2+]i and contractions were inhibited by... -
Resveratrol Inhibits Nicotinic Stimulation-Evoked Catecholamine Release from the Adrenal Medulla
Seong-ChangWoo, Gwang-MoonNa, Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.4 5 155-164 (10 pages)
Resveratrol has been known to possess various potent cardiovascular effects in animal, but there is little information on its functional effect on the secretion of catecholamines (CA) from the perfused model of the adrenal medulla. Therefore, the aim of the present study was to determine the effect of resveratrol on the CA secretion from the isolated perfused model of the normotensive rat adrenal gland, and to elucidate its mechanism of action. Resveratrol (10∼100ՌM) during perfusion into... -
Influence of ω-Conotoxin GVIA, Nifedipine and Cilnidipine on Catecholamine Release in the Rat Adrenal Medulla
Byung-SikYu, Byeong-CheolKim, Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.1 4 21-30 (10 pages)
The present study was designed to establish comparatively the inhibitory effects of cilnidipine (CNP), nifedipine (NIF), and ω-conotoxin GVIA (CTX) on the release of CA evoked by cholinergic stimulation and membrane depolarization from the isolated perfused model of the rat adrenal medulla. CNP (3 μM), NIF (3μM), and CTX (3μM) perfused into an adrenal vein for 60 min produced greatly inhibition in CA secretory responses evoked by ACh (5.32⁓103 M), DMPP (104 M for 2 min),...


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