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전체 선택해제
총 822건 검색
본문검색 결과만 보기
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Expressional Profiling of Telomerase and Telomere-Associated Molecules in the Rat Testis and Seminal Vesicle during Postnatal Developmental Period
Seo. Hee-Jung, Lee. Seong-Kyu, Baik. Haing-Woon, Cheon. Yong-Pil, Chun. Tae-Hoon, Choi. In-Ho, Lee. Ki-Ho 한국동물자원과학회 한국동물자원과학회지 8 Pages
한국동물자원과학회 한국동물자원과학회지 2011, Vol.53 No.3 195-202 (8 pages)
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Effects of Exposure Period on the Developmental Toxicity of 2-Bromopropane in Sprague-Dawley Rats
Shin. In-Sik, Lee. Jong-Chan, Kim. Kang-Hyeon, Ahn. Tai-Hwan, Bae. Chun-Sik, Moon. Chang-Jong, Kim. Sung-Ho, Shin. Dong-Ho, Kim. Jong-Ch 한국독성학회 Toxicological research 9 Pages
한국독성학회 Toxicological research 2008, Vol.24 No.4 263-271 (9 pages)
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Developmental Toxicity by Exposure to Bisphenol A Diglycidyl Ether during Gestation and Lactation Period in Sprague-dawley Male Rats
Hyoung. Un-Jun, Yang. Yun-Jung, Kwon. Su-Kyoung, Yoo. Jae-Hyoung, Myoung. Soon-Chul, Kim. Sae-Chul, Hong. Yeon-Pyo 대한예방의학회 Journal of preventive medicine and public health 7 Pages
대한예방의학회 Journal of preventive medicine and public health 2007, Vol.40 No.2 155-161 (7 pages)
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Developmental changes in cell proliferation and apoptosis in the normal duck bursa of Fabricius
Jing Fang, Xi Peng 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 4호 2 465-474 (10 pages)
The aim of this work was to investigate developmental changes in cell proliferation and apoptosis in normal duck bursa of Fabricius using flow cytometry and immunohistochemistry. Studies were carried out on Tianfu ducks on days 24 and 27 of embryogenesis (E24 and E27) along with days 20, 70, and 200 of postnatal development (P20, P70, and P200). Results showed that the percentage of G0/G1 bursa cells significantly increased between E24 and P200 while the percentage of cells in the S phase or G2... -
Developmental changes in GABAA tonic inhibition are compromised by multiple mechanisms in preadolescent dentate gyrus granule cells
SudipPit, GyuSeungLee, JinBongPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.6 15 695-702 (8 pages)
a developmental increase in GABA transporter (GAT) expression, combined with gradual decrease in GABAAR α5 subunit, resulted in various Itonic in the dentate gyrus granule cells (DGGCs) of preadolescent rats. Both GAT-1 and GAT-3 expression gradually increased at infantile (P6-8 and P13-15) and juvenile (P20-22 and P27-29) stages, with stabilization observed thereafter in adolescents (P34-36) and young adults (P41-43). Itonic facilitation of a selective GAT-1 blocker (NO-711) was significantly... -
Enhancement of GluN2B Subunit-Containing NMDA Receptor Underlies Serotonergic Regulation of Long-Term Potentiation after Critical Period in the Rat Visual Cortex
KayoungJoo, Duck-JooRhie, , Hyun-JongJang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.6 7 523-531 (9 pages)
neurotransmissions were responsible for the suppression of LTP at 5 weeks and the facilitation of LTP at 8 weeks, respectively. These results indicate that the effects of 5-HT on neurotransmission change with development, and the changes may underlie the differential regulation of synaptic plasticity between different age groups. Thus, the developmental changes in 5-HT function should be carefully considered while investigating the 5-HT-mediated metaplastic control of the cortical network. -
Developmental Switch of the Serotonergic Role in the Induction of Synaptic Long-term Potentiation in the Rat Visual Cortex
Sung-WonPark, Hyun-JongJang, Kwang-HyunCho, , Myung-JunKim, ShinHeeYoon, Duck-JooRhie 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.1 10 65-70 (6 pages)
long-term potentiation (LTP) and long-term depression (LTD) have been studied as mechanisms of ocular dominance plasticity in the rat visual cortex. Serotonin (5-hydroxytryptamine, 5-HT) inhibits the induction of LTP and LTD during the critical period of the rat visual cortex (postnatal 3∼5 weeks). However, in adult rats, the increase in 5-HT level in the brain by the administration of the selective serotonin reuptake inhibitor (SSRI) fluoxetine reinstates ocular dominance plasticity and LTP in... -
Developmental Disability Animal Model Based on Neonatal Lipopolysaccharide with Altered 5-HT Function
JaeGooKim, MinSooKim, SeoulLee, GunTaeKim, JongDooLee, DongGooKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.3 6 113-119 (7 pages)
Developmental disability shows life-long behavioral abnormality with no significant physical malformation. This study was undertaken to develop an animal model for developmental disability by using two-factor approach. Lipopolysaccharide (LPS), a bacterial toxin, and NAN-190, a 5-HT1A receptor antagonist, were administered to Sprague-Dawley rats on postnatal day (PND) 5 to induce inflammation and an altered 5-HT system, respectively. Long-term alteration of behavior occurred in the drug-treated... -
Developmental Changes of Gustatory Neurons in Nucleus of Solitary Tract in Rats
MiwonKim, WonjaeKim, CharlotteMistretta 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.3 1 169-175 (7 pages)
To learn the developmental changes in intrinsic electrophysiological properties of the second order taste neurons, whole cell recordings from the developing nucleus of the solitary tract neurons were done in brainstem slices of postnatal rats. Rats aged from postnatal 0 to 21 days (P0-P21) were used, being divided into 3 age groups: postnatal first week (P0-P7 days), second week (P8-P14 days), and third week (P15-P21 days). Slices containing gustatory NTS were cut horizontally in the thickness... -
Unbalanced diet of children with developmental disabilities seen in blogs -Focusing on the cases where they corresponded the unbalanced diet-
AJIMI Akiko, TOKUDA Katsumi, MIZUNO Tomomi, NISHIDATE Arisa, NISHIMURA Miho, OKOSHI Kazumi 아시아아동지원학회 아시아아동지원연구 9 Pages
아시아아동지원학회 아시아아동지원연구 2013, 제 4권 9 69-77 (9 pages)
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Case Study on Small Group Art Therapy for Social Skill Improvement of Children with Developmental Disability
CHO Eunah, KIM Yongseob 아시아장애사회학회 아시아장애사회학연구 14 Pages
아시아장애사회학회 아시아장애사회학연구 2014, 제 13권 3 29-42 (14 pages)
are as follows: First, small group art therapy activities were found to have positive effects on the cooperation skill improvement of children with developmental disability Second, small group art therapy activities were found to have positive effects on the self-assertion skill improvement of children with developmental disability. Third, small group art therapy activities were found to have positive effects on the self-control skill improvement of children with developmental disability. -
Exploring the Connection between a Developmental Change and Relationship Development with Caregivers and Peers
Min sun Shin, Seung Yeon Lee 환태평양유아교육연구학회 Asia-Pacific journal of research in early childhood education 26 Pages
환태평양유아교육연구학회 Asia-Pacific journal of research in early childhood education 2011, Vol.5 No.2 1 1-26 (26 pages)
major developmental transition, specifically from 10 months to 14 months. The data were collected through multiple sources, including observations, interviews, documents, and researcher journals, for a semester. Among the developmental achievements the infant gained in this study, her independent walking ability appeared to influence her relationships most. As her independent walking ability enabled the infant to gain a greater access to peers and caregivers, her presence in the room and social... -
Biological Control Developmental Characteristics of Diadegma semiclausum Hellen (Hymenoptera: Ichneumonidae), a Larval Parasitoid of Plutella xylostella L. (Lepidoptera: Yponomeutidae)
Kwon. Min, Park. Kang-Ryong, Kwon. Hye-Jin 한국응용곤충학회 Journal of Asia-Pacific entomology 6 Pages
한국응용곤충학회 Journal of Asia-Pacific entomology 2003, Vol.6 No.1 105-110 (6 pages)
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Managing Developmental Dyslexia: Practices of Speech-Language Therapists in South Africa
Salom? Geertsema, Mia Le Roux 환태평양유아교육연구학회 Asia-Pacific journal of research in early childhood education 28 Pages
환태평양유아교육연구학회 Asia-Pacific journal of research in early childhood education 2020, Vol.14 No.1 4 71-98 (28 pages)
as their perceptions regarding developmental dyslexia (DD) management. The main aim was to determine the nature of DD management practices of SLTs in South Africa (SASLT). Method: A survey study with an embedded design was employed. More specifically, a descriptive, correlational study was conducted which included qualitative and quantitative data in the same general time period. Results: Results indicated that the majority of SASLTs do not manage DD and are not confident in their ability to... -
The effects of therapeutic ultrasound stimulation on the inflammation cytokine in rat articular chondrocytes
Eun-Jung Kim, Su-jin Hwang, Gye-Yeop Kim 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2013, 제 2권 제 1호 4 21-26 (6 pages)
Objective: The aim of this study was to investigate the effect of therapeutic ultrasound (US) of cell viability and inflammatory cytokine in rat articular chondrocyte cultures stimulated with lipopolysaccharide (LPS). Design: One group pretest-posttest design. Methods: Cultured chondrocytes were treated with US and/or LPS and assessed for viability, Tumor necrosis factor (TNF)-α and Interleukin (IL)-1 production. Results: Oxidative stress was induced in rat chondrocytes with LPS. The cell... -
한반도 선사·고대 동물(動物) 사육(飼育)의 역사와 그 의미
이준정 한국고고학회 한국고고학전국대회 발표문 19 Pages
한국고고학회 한국고고학전국대회 발표문 제36회 한국고고학대회 4 71-89 (19 pages)
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Examining the possibilities for children’s digital literacy practices at home: Two theoretical perspectives
Lisa Kervin 경인교육대학교 교육연구원 The Journal of Education 14 Pages
경인교육대학교 교육연구원 The Journal of Education 2020, Vol.3 No.2 6 95-108 (14 pages)
television advertisement that showcased children at play, and was first seen during the isolation period, I look to how various semiotics including speech, colour, movement, image and sound work together to build our understanding of the potential for children’s digital literacy. Looking at this as an instance of social semiotics, I then use Engeström s (1993) activity theory to further understand digital experiences in home contexts as I examine the relationships between issues of access,... -
Analysis of Operation and Development of Online Learning Systems for Software Education
Han Sun-Gwan 경인교육대학교 교육연구원 The Journal of Education 14 Pages
경인교육대학교 교육연구원 The Journal of Education 2019, Vol.2 No.1 1 1-14 (14 pages)
This study introduces a case of operating the online learning systems for the activation of Software Education as computer science in Korea. Software Education in Korea has emphasized a having computational thinking through a programmable computing capabilities. We have designed the online learning systems that are easy for users to access. Learning areas are divided into six categories: programming, computer science theory, physical computing, computational thinking, software education, and... -
물체의 움직임 관련 활동이 유아의 과학적 탐구능력에 미치는 영향
김한나(Kim Han Na) 한국교원대학교 유아교육연구소 한국유아교육연구 21 Pages
한국교원대학교 유아교육연구소 한국유아교육연구 2010, 제 12권 제 1호 5 99-119 (21 pages)
본 연구의 목적은 물체의 움직임 관련 활동이 유아의 과학적 탐구능력 및 과학적 탐구능력의 구성 요소인 예측하기, 관찰하기, 분류하기, 측정하기, 토의하기에 어떠한 영향을 미치는지 알아보고자 하는 것이다. 본 연구의 대상은 서울시 구로구에 위치한 S초등학교병설유치원에 재원중인 만5세 유아 40명으로 실험집단 20명과 통제집단 20명 이었다. 본 연구의 결과 물체의 움직임 관련 활동이 유아의 과학적 탐구능력 및 과학적 탐구능력의 구성요소인 예측하기, 관찰하기, 분류하기, 측정하기, 토이하기에 긍정적 영향을 미치는 것으로... -
대인인지에 어려움을 보이는 유아의 모래상자놀이 적용 사례연구
권혜선(Kwon Hye-Sun) 한국교원대학교 유아교육연구소 한국유아교육연구 30 Pages
한국교원대학교 유아교육연구소 한국유아교육연구 2014, 제 16권 제 1호 6 119-148 (30 pages)
이 연구는 대인인지에 어려움을 보이는 유아가 모래상자놀이 과정에서 어떻게 자아를 표현하고, 그 양상이 어떻게 변화되어 가는지를 살펴보고, 모래상자놀이의 적용 효과는 어떠한지를 분석해보았다. 연구대상 유아는 6년 4개월 된 남아 1명으로 유아가 때때로 다른 사람 앞에서 자신을 드러내는 일에 지나치게 소극적인 자세와 경직된 태도를 보이는 문제로 의뢰해 온 유아였다. 연구절차는 모래상자놀이실시, 모래상자놀이 표현, 모래상자놀이의 적용 효과로 진행되었다. 모래상자놀이도구는 Kalff(1996)가 제시한 방법에 따라 2013년... -
유아의 상상적 내러티브에 나타난 의도(Intention)의 탐색
오아름(Oh Ah-Reum) 한국교원대학교 유아교육연구소 한국유아교육연구 32 Pages
한국교원대학교 유아교육연구소 한국유아교육연구 2015, 제 17권 제 1호 3 45-76 (32 pages)
본 연구는 상상적 내러티브에 나타난 이야기를 만드는 유아의 의도와 상상적 내러티브에 나타난 등장인물의 의도는 어떠한지 탐색함으로써 유아의 의도에 대한 구체적이고 의미 있는 이해를 돕고자하는데 그 목적이 있다. 이를 위해 만 5세 유아 총 24명을 연구참여자로 하여 5주간 유아의 상상적 내러티브 내용을 수집하고, 내러티브에 나타난 의도를 이해하기 위한 참여관찰, 면담, 기타자료 수집 등의 질적 연구를 수행하였다. 연구 결과 첫째, 상상적 내러티브에 나타난 이야기를 만드는 유아의 의도는 「이야기 지식을 활용하려는... -
사진을 활용한 은유적 표현활동에 관한 연구
윤혜경(Yun Hye-Kyeong), 최연철(Choi Youn-chul) 한국교원대학교 유아교육연구소 한국유아교육연구 21 Pages
한국교원대학교 유아교육연구소 한국유아교육연구 2017, 제 19권 제 2호 2 17-37 (21 pages)
본 논문에서는 사진에서 나타난 유아의 은유적 표현에 대해 알아보았다. 유아가 유치원과 가정에서 찍은 사진을 활용하여 이야기 나누기를 하는 동안 새로운 사고가 표출되었으며 다양한 은유적 표현이 나타났다. 본 연구에서 나타난 유아의 은유는, 자신의 경험에 기반을 둔 은유적 표현, 유아의 적극적인 사진 읽기와 은유적 표현, 함께 나누며 더해지는 은유적 표현으로 유목화하였다 -
STB-HO, a novel mica fine particle, inhibits the teratoma-forming ability of human embryonic stem cells after in vivo transplantation
Soon Won Choi, Tae Hoon Shin, Ji Hee Shin, Byung Chul Lee, In sung Kang, Hafiz Uddin, Yoo jin Seo, Hyung Sik Kim, Kyung Sun Kang 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 306 501-502 (2 pages)
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Non-cytotoxic concentrations of aflatoxin B1 affect the development of hepatocyte progenitor cells to hepatocytes using human induced pluripotent stem cell
Seok Jin Kang, Hyuk Mi Lee, Young Il Park, Jae Young Song, Hwan Goo Kang 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 305 501-501 (1 pages)
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Effects of non-cytotoxic concentrations of chemicals on the development of hepatocyte progenitor cells to hepatocytes using human embryonic stem cells
Seok Jin Kang, So Ryeon Hwang, Young Il Park, Jae Young Song, Hwan Goo Kang, Hyun Ok Ku 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 394 406-406 (1 pages)
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High prevalence of Hepatitis E virus antibodies on wildboars (Sus scrofa) in Republic of Korea
Ji Young Park, Eun Mi Kim, Ha Chung Yoon, Yu Ri Park, Woo Seuk Jeong, Dong Jun An, Seung Yoon Lee, Sang Geon Yeo, Choi Kyu Park 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 393 405-406 (2 pages)
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Toxicities of disinfectants of animal health and sanitation products using different test organisms
Dong Yoon Kim, Hyun Jung Choi, Joo Yong Kang, Jung Woon Kim, Ba Reum Kwon, Sol Jang, Seong Jin Baek, Chang Seon Song, Seong Su Yuk 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 385 400-400 (1 pages)
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Effects of non-cytotoxic concentrations of chemicals on the development of hepatocyte progenitor cells to hepatocytes using human embryonic stem cells
Seok Jin Kang, So Ryeon Hwang, Young Il Park, Jae Young Song, Hwan Goo Kang, Hyun Ok Ku 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 384 399-400 (2 pages)
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The change of histopathology and TNF-α immunohistochemistry in the heart of rat after asphyxial cardiacarrest
Hyun Jin Tae, Anowarul Islam, Rashedunnabi Aka, Weishun Tian, Tae Kyeong Lee, Jae chul Lee, Taek Geun Ohk, Jun Hwi Cho, Moo Ho Won, In Sh 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 259 350-351 (2 pages)
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A Salmonella Typhi ghost induced by the E gene of phage X174 stimulates dendritic cells and efficiently activates the adaptive immune response
Gayeon Won, Seong Kug Eo, Sang-Youel Park, Jin Hur, John Hwa Lee 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 4호 9 536-542 (7 pages)
Previously, we genetically engineered a Salmonella Typhi bacterial ghost (STG) as a novel inactivated vaccine candidate against typhoid fever. The underlying mechanism employed by the ghost in stimulating the adaptive immune response remains to be investigated. In this study, we aimed to evaluate the immunostimulatory effect of STG on mouse bone marrow-derived dendritic cells (BMDCs) and its activation of the adaptive immune response in vitro. Immature BMDCs were stimulated with STG, which... -
Clinical assessment after human adipose stem cell transplantation into dogs
Seok Hee Lee, Erif M.N. Setyawan, Yoo Bin Choi, Jeong Chan Ra, Sung Keun Kang, Byeong Chun Lee, Geon A Kim 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 3호 15 452-461 (10 pages)
Adipose tissue-derived stem cell (ASCs) are an attractive source of stem cells with therapeutic applicability in various fields for regenerating damaged tissues because of their stemness characteristics. However, little has reported on evaluating adverse responses caused by human ASC therapy. Therefore, in the present study, a clinical assessment after human ASC transplantation into dogs was undertaken. A total of 12 healthy male dogs were selected and divided into four groups: saline infusion,... -
Microglial involvement in the development of olfactory dysfunction
Yoojin Seo, Hyung-Sik Kim, Kyung-Sun Kang 대한수의학회 Journal of Veterinary Science 12 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 3호 1 319-330 (12 pages)
Olfactory impairment is the most common clinical manifestation among the elderly, and its prevalence increases sharply with age. Notably, growing evidence has shown that olfactory dysfunction is the first sign of neurodegeneration, indicating the importance of olfactory assessment an early marker in the diagnosis of neurological disorders. In this review, we describe the nature of olfactory dysfunction and the advantage of using animal models in olfaction study, and we include a brief... -
Analysis of structure-function relationship in porcine rotavirus A enterotoxin gene
Sharad Saurabh, Shubhankar Sircar, Jobin J. Kattoor, Souvik Ghosh, Nobumichi Kobayashi, Krisztian Banyai, Obli R. VinodhKumar, U 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 1호 6 35-43 (9 pages)
Rotavirus (RV)-infected piglets are presumed to be latent sources of heterologous RV infection in humans and other animals. In RVs, non-structural protein 4 (NSP4) is the major virulence factor with pleiotropic properties. In this study, we analyzed the nsp4 gene from porcine RVs isolated from diarrheic and non-diarrheic cases at different levels of protein folding to explore correlations to diarrhea-inducing capabilities and evolution of nsp4 in the porcine population. Full-length nsp4 genes... -
Molecular cloning and characterization of porcine ribosomal protein L21
Wu-Sheng Sun, Ju-Lan Chun, Dong-Hwan Kim, Jin-Seop Ahn, Min-Kyu Kim, In-Sul Hwang, Dae-Jin Kwon, Seongsoo Hwang, Jeong-Woong Lee 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 4호 18 531-540 (10 pages)
Ribosomal protein L21 (RPL21) is a structural component of the 60S subunit of the eukaryotic ribosome. This protein has an important role in protein synthesis and the occurrence of hereditary diseases. Pig is a common laboratory model, however, to the best of our knowledge, its RPL21 gene has not been cloned to date. In this study, we cloned and identified the full-length sequence of the pig RPL21 gene for the first time. In addition, we examined its expression pattern and function by using... -
Reactive oxygen species-mediated unfolded protein response pathways in preimplantation embryos
Ihsan Ali, Syed Zahid Ali Shah, Yi Jin, Zhong-Shu Li, Obaid Ullah, Nan-Zhu Fang 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 1호 1 1-9 (9 pages)
Excessive production of reactive oxygen species (ROS) and endoplasmic reticulum (ER) stress-mediated responses are critical to embryonic development in the challenging in vitro environment. ROS production increases during early embryonic development with the increase in protein requirements for cell survival and growth. The ER is a multifunctional cellular organelle responsible for protein folding, modification, and cellular homeostasis. ER stress is activated by a variety of factors including...
