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251.

Fenofibrate Reduces Age-related Hypercholesterolemia in Normal Rats on a Standard Diet

YingHan, Mi-HyangDo, MiSunKim, EunhuiSeo, Mi-KyoungPark, DukKyuKim, Hye-JeongLee, Su-YeongSeo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.2 3 77-81 (5 pages)

YingHan, Mi-HyangDo, MiSunKim, EunhuiSeo, Mi-KyoungPark, DukKyuKim, Hye-JeongLee, Su-YeongSeo 저
...
- 1,500원
Plasma cholesterol is increased in normal aging in both rodents and humans. This is associated with reduced elimination of cholesterol and decreased receptor-mediated clearance of plasma low-density lipoprotein (LDL) cholesterol. The aims of this study were: (1) to determine age-related changes in plasma lipid profiles, and (2) to determine the effect of fenofibrate, an activator of peroxisome proliferator activated receptor alpha (PPAR Ձ), on plasma lipid profiles in normal rats on a...
252.

Efficient Management Design for Swimming Exercise Treatment

KyunghunKim, TaewonKyung, WonhyunKim, ChungsickShin, YoungjaeSong, MooYeolLee, HyunwooLee, YongchanCho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.6 14 497-502 (6 pages)

KyunghunKim, TaewonKyung, WonhyunKim, ChungsickShin, YoungjaeSong, MooYeolLee, HyunwooLee, YongchanCho 저
...
- 3,000원
Exercise-mediated physical treatment has attracted much recent interest. In particular, swimming is a representative exercise treatment method recommended for patients experiencing muscular and cardiovascular diseases. The present study sought to design a swimming-based exercise treatment management system. A survey questionnaire was completed by participants to assess the prevalence of muscular and cardiovascular diseases among adult males and females participating in swimming programs at sport...
253.

Possible Involvement of Ca2＋ Activated K＋ Channels, SK Channel, in the Quercetin-Induced Vasodilatation

SeiichiroNishida, HiroyasuSatoh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.5 5 361-365 (5 pages)

SeiichiroNishida, HiroyasuSatoh 저
...
- 1,500원
Effects of quercetin, a kind of flavonoids, on the vasodilating actions were investigated. Among the mechanisms for quercetin-induced vasodilatation in rat aorta, the involvement with the Ca2＋ activated K＋ (KCa) channel was examined. Pretreatment with NE (5ՌM) or KCl (60 mM) was carried out and then, the modulation by quercetin of the constriction was examined using rat aorta ring strips (3 mm) at 36.5oC. Quercetin (0.1 to 100ՌM) relaxed the NE-induced vasoconstrictions in a...
254.

P2X7 Receptor-mediated Membrane Blebbing in Salivary Epithelial Cells

Sung-MinHwang, Na-YounKoo, Se-YoungChoi, Gae-SigChun, Joong-SooKim, KyungpyoPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.3 6 175-179 (5 pages)

Sung-MinHwang, Na-YounKoo, Se-YoungChoi, Gae-SigChun, Joong-SooKim, KyungpyoPark 저
...
- 1,500원
High concentrations of ATP induce membrane blebbing. However, the underlying mechanism involved in epithelial cells remains unclear. In this study, we investigated the role of the P2X7 receptor (P2X7R) in membrane blebbing using Par C5 cells. We stimulated the cells with 5 mM of ATP for 1∼2 hrs and found the characteristics of membrane blebbing, a hallmark of apoptotic cell death. In addition, 500ՌM Bz-ATP, a specific P2X7R agonist, induced membrane blebbing. However, 300ՌM of...
255.

Inhibition of the Desensitization of Canonical Transient Receptor Potential Channel 5 by Dimethyl Sulfoxide

ByungJooKim, InsukSo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.5 10 227-231 (5 pages)

ByungJooKim, InsukSo 저
...
- 1,500원
The classic type of transient receptor potential channel (TRPC) is a molecular candidate for Ca2+-permeable cation channel in mammalian cells. TRPC5 is rapidly desensitized after activation by G protein-coupled receptor. Herein we report the effect of dimethyl sulfoxide (DMSO) on the desensitization of TRPC5. TRPC5 was initially activated by muscarinic stimulation with 50μM carbachol (CCh) and then decayed rapidly even in the presence of CCh (desensitization). DMSO in the pipette solution...
256.

Effects of R. Glutinosa and E. Senticosus on Postmenopausal Osteoporosis

SooYeonOh, DipendraKumarAryal, Yoon-GyoonKim, , Hyung-GunKim, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.3 7 121-127 (7 pages)

SooYeonOh, DipendraKumarAryal, Yoon-GyoonKim, , Hyung-GunKim, 저
...
- 3,000원
In this study, we investigated the therapeutic effects of a novel formulation of low-dose calcium and vitamin D3, blended with Rehmannia glutinosa Libosch and Eleutherococcus senticosus Max (RE⁢), in postmenopausal women. The controls were given either a placebo or high dose calcium and vitamin D3 (Ca⁢D). Bone mineral density (BMD) in the L2-3 lumber spines and femur regions was assessed, and serum osteocalcin, bone-specific alkaline phosphatase (BALP), and cross-linked N-telopeptide...
257.

Androgen Hormone Inhibits Expression of iNOS and COX-2 Protein in Rat Vascular Smooth Muscle Cell

HwaYoungBae, JiEunPark, EunMiJeon, YoungJinKang, KwangYounLee, HyoungChulChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.4 5 215-222 (8 pages)

HwaYoungBae, JiEunPark, EunMiJeon, YoungJinKang, KwangYounLee, HyoungChulChoi 저
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- 3,000원
We investigated the effects of testosterone and dihydrotestosterone on inflammatory response of iNOS and COX-2 expression in rat vascular smooth muscle cells. Rat vascular smooth muscle cells (VSMC) stimulated with bacterial lipopolysaccharide (LPS; 10μg/ml) for 24 hours were incubated with increasing amounts of testosterone and dihydrotestosterone (1 and 100 nM). LPS was found to induce inflammatory response of iNOS and COX-2 mRNA and protein in VSMC. These processes were affected by male sex...
258.

The Improvement of Learning and Memory Ability of Normal Persons by BF-7

SangHyungLee, YongSikKim, YongKooKang, OhSangKwon, YongKyooShin, JinHoSong, MooYeolLee, Kwang-GillLee, Joo-HongYeo, WonBokLee, TaeJinLee, S 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.6 3 307-312 (6 pages)

SangHyungLee, YongSikKim, YongKooKang, OhSangKwon, YongKyooShin, JinHoSong, MooYeolLee, Kwang-GillLee, Joo-HongYeo, WonBokLee, TaeJinLee, S 저
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- 3,000원
To investigate whether BF-7, extracted from Bombyx mori, improved learning and memory of ordinary people, Rey-Kim Memory Test was performed with placebo group (32 persons), 200 mg BF-7 treated group (33 persons) and 400 mg BF-7 treated group (34 persons). BF-7 enhanced significantly learning and memory function in a dose-dependent manner. To know how BF-7 plays such a positive role, we measured the concentration of acetylcholine in the brain from memory impairment animal model. Treatment of BF-7...
259.

The Role of BF-7 on Neuroprotection and Enhancement of Cognitive Function

Hee-SunChae, YongKooKang, YongKyuShin, HyunJungLee, Ji-InYu, KwangGillLee, JooHongYeo, YongSikKim, Dong-SuepSohn, KyungYongKim, WonBokLee, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.4 1 173-180 (8 pages)

Hee-SunChae, YongKooKang, YongKyuShin, HyunJungLee, Ji-InYu, KwangGillLee, JooHongYeo, YongSikKim, Dong-SuepSohn, KyungYongKim, WonBokLee, 저
...
- 3,000원
Amyloid β-peptide (Aβ) contributes to the pathogenesis of Alzheimer's disease (AD), causing neuronal death through apoptosis. In this study, the neuroprotective role of BF-7, extracted form sericultural product, was examined against Aβ -induced toxicity in cultured human neuronal cell SKN-SH. In order to know if the BF-7 has positive role on the cognition and memory in human, the mixture of BF-7, DHA and EPA (BDE) was examined using Rey Kim and K-WAIS test with 50 healthy high school student....
260.

Role of Calmodulin in the Generation of Reactive Oxygen Species and Apoptosis Induced by Tamoxifen in HepG2 Human Hepatoma Cells

YongSooLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.4 3 187-192 (6 pages)

YongSooLee 저
...
- 3,000원
Tamoxifen, an antiestrogen, has previously been shown to induce apoptosis in HepG2 human hepatoblastoma cells through activation of the pathways independent of estrogen receptors, i.e., intracellular Ca2⁢ increase and generation of reactive oxygen species (ROS). However, the mechanism of tamoxifen to link increased intracellular Ca2⁢ to ROS generation is currently unknown. Thus, in this study we investigated the possible involvement of calmodulin, a Ca2⁢ activated protein, and...

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