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Modulation of radiation response in endothelial cells by GGA
Na Kyung Han, Ye Ji Jeong, Hae June Lee 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 325 369-370 (2 pages)
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Transcriptomics of neurogenesis in chronic RF-exposed hippocampus
Ye Ji Jeong, Na Kyung Han, Jong Hwa Kwon, Hae June Lee 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 324 369-369 (1 pages)
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Comparative aspects of microRNA expression in canine and human cancers
Kabiru Sahabi, Gayathri T. Selvarajah, Rasedee Abdullah, Yoke Kqueen Cheah, Geok Chin Tan 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 2호 2 162-171 (10 pages)
MicroRNAs (miRNAs) have important roles in all biological pathways in multicellular organisms. Over 1,400 human miRNAs have been identified, and many are conserved among vertebrates and invertebrates. Regulation of miRNA is the most common mode of post-transcriptional gene regulation. The miRNAs that are involved in the initiation and progression of cancers are termed oncomiRs and several of them have been identified in canine and human cancers. Similarly, several miRNAs have been reported to be... -
Development and clinical evaluation of a rapid diagnostic kit for feline leukemia virus infection
Won-Shik Kim, Chom-Kyu Chong, Hak-Yong Kim, Gyu-Cheol Lee, Wooseog Jeong, Dong-Jun An, Hye-Young Jeoung, Jae-In Lee, Young-Ki Le 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 1호 10 91-97 (7 pages)
prepared monoclonal antibodies specific for the FeLV p27 to develop a rapid diagnostic test with enhanced sensitivity and specificity. Among these antibodies, we identified two clones (hybridomas 8F8B5 and 8G7D1) that specifically bound to FeLV and were very suitable for a diagnostic kit. The affinity constants for 8F8B5 and 8G7D1 were 0.35 × 10 and 0.86 × 10, respectively. To investigate the diagnostic abilities of the rapid kit using these antibodies, we performed several clinical studies.... -
Vitamin D3 up-regulated protein 1 controls the priming phase of liver regeneration
Hyo-Jung Kwon, Sung-Kuk Hong, Won-Kee Yoon, Ki-Hoan Nam, In-Pyo Choi, Dae-Yong Kim, Hyoung-Chin Kim, Young-Suk Won 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 3호 4 257-262 (6 pages)
Vitamin D3 up-regulated protein 1 (VDUP1) is a potent growth suppressor that inhibits tumor cell proliferation and cell cycle progression when overexpressed. In a previous study, we showed that VDUP1 knockout (KO) mice exhibited accelerated liver regeneration because such animals could effectively control the expression of cell cycle regulators that drive the G1-to-S phase progression. In the present study, we further investigated the role played by VDUP1 in initial priming of liver... -
The critical time of avian leukosis virus subgroup J-mediated immunosuppression during early stage infection in specific pathogen-free chickens
Feng Wang, Xiaowei Wang, Hongbo Chen, Jianzhu Liu, Ziqiang Cheng* 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2011, 제 12권 제 3호 6 235-241 (7 pages)
The critical time of avian leukosis virus subgroup J (ALV-J)-mediated immunosuppression was determined by body weight, relative immune organ weight, histopathology, and presence of group specific antigen and antibodies in specific pathogen-free (SPF) chickens. CD4 and CD8 cell activity in the spleen, total and differential leukocyte counts in blood, and viral RNA levels in spleen were measured. Significant growth suppression was observed in the two ALV-J-infected groups. A strong immune response... -
Dendrotoxin-ĸ suppresses tumor growth induced by human lung adenocarcinoma A549 cells in nude mice
Soo Hwa Jang, Pan Dong Ryu, So Yeong Lee* 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2011, 제 12권 제 1호 6 35-40 (6 pages)
adenocarcinoma cell line A549 in a xenograft model. Kv1.1 mRNA and protein was expressed in A549 cells and the blockade of Kv1.1 by DTX-ĸ, reduced tumor formation in nude mice. Furthermore, treatment with DTX-ĸ significantly increased protein expression of p21, p27, and p15 and significantly decreased protein expression of cyclin D3 in tumor tissues compared to the control. These results suggest that DTX-ĸ has anti-tumor effects in A549 cells through the pathway governing G1-S transition. -
Low dietary inorganic phosphate affects the lung growth of developing mice
Cheng-Xiong Xu, Hua Jin, Youn-Sun Chung, Ji-Young Shin, Soon-Kyung Hwang, Jung-Taek Kwon, Sung-Jin Park, Eun-Sun Lee, Arash Mina 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2009, 제 10권 제 2호 3 105-113 (9 pages)
Inorganic phosphate (Pi) plays a critical role in diverse cellular functions, and regulating the Pi balance is accomplished by sodium-dependent Pi co-transporter (NPT). Pulmonary NPT has recently been identified in mammalian lungs. However, to date, many of the studies that have involved Pi have mainly focused on its effect on bone and kidney. Therefore, current study was performed to discover the potential effects of low Pi on the lung of developing transgenic mice expressing the... -
Overexpression of cyclin D1 and cyclin E in 1,2-dimethylhydrazine dihydrochloride-induced rat colon carcinogenesis
Kwon Hur, Jung-Rae Kim, Byung-Il Yoon, Jung-Keun Lee, Jae-Hoon Choi, Goo-Taeg Oh, Dae-Yong Kim 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2000, 제 1권 제 2호 9 121-126 (6 pages)
Deregulation of G1 cyclins has been reported in several human and rodent tumors including colon cancer. To investigate the expression pattern of G1 cyclins in 1,2- dimethyl-hydrazine dihydrochloride (DMH)-induced rat colon carcinogenesis, we studied the expression of cyclin D1 and cyclin E by quantitative reverse transcription-polymerase chain reaction (RT-PCR) analysis and immunohistochemistry (IHC). The mRNA level of cyclin D1 was increased 1.2-fold in adenocarcinomas but not significantly in...


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