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671.

Effect of UV Irradiation and Rebamipide on the Blood Flow and Viability of Rabbit Skin Flap

Eung-JooSuh, Hyoung-ChulChoi, Uy-DongSohn, Jeoung-HeeHa, Kwang-YounLee, Won-JoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.5 14 581-589 (9 pages)

Eung-JooSuh, Hyoung-ChulChoi, Uy-DongSohn, Jeoung-HeeHa, Kwang-YounLee, Won-JoonKim 저
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- 3,000원
to be enhanced by intradermal injection of L-NAME, a nitric oxide synthase (NOS) inhibitor, but the regression was significantly reversed by acetylcholine, an endothelial constitutive NOS (cNOS) activator and L-arginine, an NO precusor. Rebamipide, a novel antiulcer agent known to scavenge the hydroxyl radical, abruptly reversed the spontaneous regression of the UVL- induced increase in BFF by the same manner as L-arginine. In ischemic skin flap, rebamipide increased the BFF abruptly by the same...
672.

Effects of Ginsenosides on the Mechanism of Histamine Release in the Guinea Pig Lung Mast Cells Activated by Specific Antigen- Antibody Reactions

JaiYoulRo, YoungSooAhn, KyungHwanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.4 11 445-456 (12 pages)

JaiYoulRo, YoungSooAhn, KyungHwanKim 저
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- 4,100원
antigen-antibody reactions via both phosphatidylinositide-PLC and phosphatidylcholine- PLD systems, and then followed by the inhibition of histamine release. However, Re increases histamine release by stimulation of DAG production, which is mediated by phosphatidylcholine-PLD system rather than by phosphatidylinositide-PLC system, but inhibits the mass DAG production. Thus, it could be inferred that other mechanisms play a role in the increase of histamine release during mast cell activation.
673.

Changes in Renal Brush-Border Sodium-Dependent Transport Systems in Gentamicin-Treated Rats

SoongYongSuhl, DoWhanAhn, KyoungRyongKim, JeeYeunKim, YangSaengPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.4 7 403-411 (9 pages)

SoongYongSuhl, DoWhanAhn, KyoungRyongKim, JeeYeunKim, YangSaengPark 저
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- 3,000원
To elucidate the mechanism of gentamicin induced renal dysfunction, renal functions and activities of various proximal tubular transport systems were studied in gentamicin-treated rats (Fisher 344). Gentamicin nephrotoxicity was induced by injecting gentamicin sulfate subcutaneously at a dose of 100 mg/kg·day for 7 days. The gentamicin injection resulted in a marked polyuria, hyposthenuria, proteinuria, glycosuria, aminoaciduria, phosphaturia, natriuresis, and kaliuresis, characteristics of...
674.

Mechanisms Underlying Relaxations Caused by Angiotensin II and Its Analogs in Isolated Rabbit Mesenteric Artery

KiWhanHong, , JiYoungPark, ChiDaeKim, WonSukLee, ByungYongRhim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.4 6 393-402 (10 pages)

KiWhanHong, , JiYoungPark, ChiDaeKim, WonSukLee, ByungYongRhim 저
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- 3,000원
arteries with endothelium, which was inhibited by L-NNA and methylene blue, respectively. 7) AII enhanced synthesis of PGF2α and 6-keto PGF1α from the arterial segments with endothelium, which was inhibitable by indomethacin, but not by L-NNA. In conclusion, the vasorelaxant responses to AII of the rabbit mesenteric artery with endothelium are subserved by arachidonic acid and its metabolites produced via activation of cyclooxygenase and cytochrome P-450 enzyme as well as by nitric oxide.
675.

Platelet-Activating Factor Enhances Interleukin-1 Activity by Alveolar Macrophages Inhibition by PAF Specific Receptor Antagonists

JiheeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 10 201-208 (8 pages)

JiheeLee 저
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- 3,000원
or lipopolysaccharide(LPS) to AM cultures markedly enhanced IL-1 activity by 2-3 fold compared with AM cultures with the stimulant alone in a concentration dependent fashion. The peack effect was found at 10⁣8 M PAF with MDP and 10⁣14 M PAF with LPS. the effect of PAF was also tested in silica, toxic respirable dust, -added AM cultures as well as in the cultures containing bacterial compounds. Although silica did not stimulate the IL-1 activity, PAF could enhance IL-1 activity by 2...
676.

Comparision of Regulatory Action of cAMP and cGMP on the Activation of Neutrophil Responses

Chang-HwangHan, Young-ChulYoon, Yong-KyooShin, Eun-SookHan, Chung-SooLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.1 13 97-105 (9 pages)

Chang-HwangHan, Young-ChulYoon, Yong-KyooShin, Eun-SookHan, Chung-SooLee 저
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- 3,000원
The regulatory role of cyclic nucleotides in the expression of neutrophil responses has been examined. fMLP-stimulated superoxide production in neutrophils was inhibited by dibutyryl adenosine 3',5'-cyclic monophosphate (DBcAMP), histamine, adenosine⁢theophylline, cAMP elevating agents, and 8-bromoguanosine 3',5'-cyclic monophosphate (8-BrcGMP) and sodium nitroprusside, cGMP elevating agents. Staurosporine, a protein kinase C inhibitor, genistein, a protein tyrosine kinase inhibitor and...
677.

Alterations in Serum BDNF and GDNF Levels after 12 Weeks of Antidepressant Treatment in Female Outpatients with Major Depressive Disorder

Young-Min Park, Bun-Hee Lee 대한신경정신의학회 Psychiatry Investigation 6 Pages

대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 11 818-823 (6 pages)

Young-Min Park, Bun-Hee Lee 저
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- 3,000원
Objective_Some clinical studies have found alterations in the levels of serum brain-derived neurotrophic factor (BDNF) and glial cell line-derived neurotrophic factor (GDNF) after applying antidepressant treatment in patients with major depressive disorder (MDD). We evaluated the serum BDNF and GDNF levels before and after 12 weeks of antidepressant treatment in MDD outpatients. Methods_Serum BDNF and GDNF levels were measured in 23 female MDD outpatients at baseline and after 12 weeks of...
678.

알쯔하이머형 치매 환자의 단핵세포 증식과 싸이토카인 생성에 대한 β-아밀로이드 펩티드의 작용

채정호, 백인호 대한신경정신의학회 신경정신의학 11 Pages

대한신경정신의학회 신경정신의학 1999, 제 38권 제 1호 17 190-200 (11 pages)

채정호, 백인호 저
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- 4,000원
연구목적： 알쯔하이머 치매의 병인론에 면역성 기전이 개입된다는 가설을 확인하고자 본 연구를 행하였다. 방 법： 알쯔하이머 치매 19명, 혈관성 치매 22명, 정상 노인 19명에서 말초 혈액 단핵세포를 분리하여 phytohemagglutinin- P(PHA-P) 및 1-40의 β-아밀로이드(Aβ)로 자극하여 세포 증식 정도를 비교하였으며, 배양 상청액에서 interleukin-1β(IL-1β)와 tumor necrosis factor-α(TNF-α)를 효소결합면역흡착분석법 으로 측정하였다. 결 과： 1) PHA-P 자극에 의한 단핵 세포의 증식은 세 군에서 차이가 없었다. 2) Aβ...
679.

백서 뇌 별아교세포에서 LipopolysaccharideI에 의한 Nitric Oxide 생성기전

소광, 박래길, 이상렬, 박민철 대한신경정신의학회 신경정신의학 13 Pages

대한신경정신의학회 신경정신의학 1999, 제 38권 제 4호 20 881-893 (13 pages)

소광, 박래길, 이상렬, 박민철 저
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- 4,200원
연구목적： Nitric oxide(NO)는 뇌졸중 및 여러 가지 신경변성 질환의 병리생리에 중요한 역할을 한다. 본 연구는 백서 뇌로부터 분리한 별아교세포에서 세균내독소 lipopolysaccharide(LPS)에 의한 NO 생성과정이 MAP kinase cascades와 전사 활성인자 NF-kB에 의해 중재됨을 밝히고자 하는 것이다. 방 법： NO 생성은 Greese’s reagents와 Western blot analysis를 사용하여 측정하였고 Erk, JNK1, p38은 in vitro immunecomplex kinase assay로 측정했다. NF-kB의 전사적 활성은 electrophoretic mobility shift assay로 결정하였다....
680.

북한이탈주민의 외상 후 스트레스 장애와 자연살해세포 활성

김병창, 정성훈, 임효덕, 최종혁, 전정희, 전양환 대한신경정신의학회 신경정신의학 7 Pages

대한신경정신의학회 신경정신의학 2008, 제 47권 제 5호 8 481-487 (7 pages)

김병창, 정성훈, 임효덕, 최종혁, 전정희, 전양환 저
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- 3,000원

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