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Pharmacokinetics and bioavailability of doxycycline in ostriches (Struthio camelus) at two different dose rates
Ehab A. Abu-Basha, Nasir M. Idkaidek, Tareq M. Hantash 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 4호 4 327-332 (6 pages)
A bioavailability and pharmacokinetics study of doxycycline was carried out on 30 healthy ostriches after a single intravenous (IV), intramuscular (IM) and oral dose of 15 mg/kg body weight. The plasma doxycycline concentration was determined by HPLC/UV at 0 (pretreatment), 0.08, 0.25, 0.5 1, 2, 4, 6, 8, 12, 24 and 48 h after administration. The plasma concentration-time curves were examined using non-compartmental methods based on the statistical moment theory for only the higher dose. After IV... -
Efficacy of VP2 protein expressed in E. coli for protection against highly virulent infectious bursal disease virus
Abdul Rahman Omar, Chong Lee Kim, Mohd Hair Bejo, Aini Ideris 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 3호 6 241-247 (7 pages)
chickens survived the hvIBDV challenge. Despite showing low antibody titer profiles, all chickens immunized with the heat-inactivated whole virus also survived the challenged with hvIBDV. However, all of these chickens had bursal atrophy and mild to moderate depletion of lymphocytes. Thus, antibodies raised against IBDV VP2 protein expressed in E. coli and denatured IBDV proteins induced some degree of protection against mortality but not against bursal damage following challenge with hvIBDV. -
Influence of endotoxin induced fever on the pharmacokinetics of intramuscularly administered cefepime in rabbits
Ayman Goudah, Samar M. Mouneir, Jae-Han Shim, A. M. Abd El-Aty 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 2호 10 151-155 (5 pages)
by a two-week washout period. An infection was induced by an intravenous inoculation of 5 × 108 colony-forming units of Escherichia coli 24 h before the pharmacokinetic investigation. A quantitative microbiological assay was employed to measure the plasma cefepime concentrations using an agar-gel diffusion method with Bacillus subtilis ATCC 6633 as the test organism. Twenty-four hour after the injection, the rectal temperature in the infected animals increased by 1°C. There was a significant... -
BSE situation and establishment of Food Safety Commission in Japan
Takashi Onodera, Chi-Kyeong Kim 대한수의학회 Journal of Veterinary Science 11 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 1호 1 1-11 (11 pages)
as Food Safety Basic Law, and 8)Establish of Food Safety Commission in the Cabinet Office.At this moment, the extent of SRM risk has only been indicated by several reports employing tests with a limited sensitivity.There is still a possibility that the items in the SRM list will increase in the future, and this indiscriminately applies to Japanese cattle as well. Although current practices of SRM elimination partially guarantee total food safety, additional latent problems and imminent issues... -
Comparison of an enzyme-linked immunosorbent assay with serum neutralization test for serodiagnosis of porcine epidemic diarrhea virus infection
Jin Sik Oh, Dae Sub Song, Jeong Sun Yang, Ju Young Song, Hyoung Joon Moon, Tae Yung Kim, Bong Kyun 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2005, 제 6권 제 4호 14 349-352 (4 pages)
from the cytoplasm of PEDV-infected Vero cells using a non-ionic detergent, Triton X-100,and a simple protocol of PEDV ELISA was followed.The presence of antibodies in these experimental samples was confirmed by SN and ELISA in which the sensitivity of the ELISA was 89.1%,and the corresponding specificity was 94.5%.On testing 1,024 field samples,an overall agreement of 84.2%was generated between the SN and ELISA.This study demonstrates that the PEDV ELISA is a useful serodiagnostic screening tes... -
Comparative evaluation of phenobarbital-induced CYP3A and CYP2H1 gene expression by quantitative RT-PCR in Bantam, Bantamized White Leghorn and White Leghorn chicks
Harshad V. Goriya, Anil Kalia, Shailesh K. Bhavsar, Chaitanya G. Joshi, Dharamshibhai N. Rank, Aswin M. Thaker 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2005, 제 6권 제 4호 3 279-285 (7 pages)
in Bantam, Bantamized White Leghorn and White Leghorn chicks. Out of 18 chicks total 3 from each group (Bantam, Bantamized White Leghorn and White Leghorn) were treated intraperitoneal with phenobarbital at the dose rate of 12 mg/100 g (body weight) while the control group was treated with the saline. Total RNA was extracted from the liver samples using Tri Reagent based method. First strand cDNA was synthesized using one step RT-PCR kit. The PCR was performed and the product was subjected to... -
Effect of probiotic containing Saccharomyces boulardii on experimental ochratoxicosis in broilers: hematobiochemical studies
S. B. Agawane, P. S. Lonkar 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2004, 제 5권 제 4호 12 359-367 (9 pages)
with ochratoxin A of 0.5 ppm along with probiotic Saccharomyces boulardii of 10 mg/kg of diet. Hematological studies carried revealed significant decrease in the haemoglobin and packed cell volume in birds of group B and reduced effect in birds of group D due to probiotic. Biochemical profiles revealed significant improvement in probiotic treated group D when compared with decreased values of Total protein, albumin, globulin and increased levels of serum creatinine and SGPT in birds of groups B. -
Effect of β -mercaptoethanol or epidermal growth factor supplementation on in vitro maturation of canine oocytes collected from dogs with different stages of the estrus cycle
Min Kyu Kim, Yuda Heru Fibrianto, Hyun Ju Oh, Goo Jang, Hye Jin Kim, Kyu Seung Lee, Sung Keun Kang, Byeong Chun Lee, Woo Suk Hwa 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2004, 제 5권 제 3호 11 253-258 (6 pages)
Supplementation of β-mercaptoethanol (β-ME) in in vitro maturation (IVM) medium was shown to improve embryo development and quality in several species. Epidermal growth factor (EGF) was also shown to improve IVM of human oocyte and embryo development after in vitro fertilization (IVF). The effect of these two compounds were suggested to be mediated through the synthesis of glutathione (GSH) which is known to play an important role in protecting the cell or embryos from oxidative damage. Thus,... -
A comparative study of gastrointestinal parasites between ranched and free ranging Burchell's zebra (Equus burchelli antiquorum) in Isiolo district, Kenya
Elizabeth N. Wambwa, W.O. Ogara, Dennis Mudakha 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2004, 제 5권 제 3호 5 215-220 (6 pages)
total worm burden was higher in the free ranging zebra 2,743,410 ±849,604 than the ranched zebra, 787,669 ± 246,006. The range of individual genera varied from 0 to 269,225 in the free ranging group, which was higher than 0 to 77,890 in the ranched animals. From statistical analysis, no significant difference could be found between males and females. However, the burdens of genera Strongylus, Triodontophorus, Crossocephalus and Parascaris were significantly higher in free ranging animals. -
Mutation and overexpression of p53 as a prognostic factor in canine mammary tumors
Chung-Ho Lee, Wan-Hee Kim, Ji-Hey Lim, Min-Soo Kang, Dae-Yong Kim and Oh-Kyeong Kweon 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2004, 제 5권 제 1호 9 63-69 (7 pages)
We concentrated ourselves to evaluate the prognostic significance of the p53 gene mutations, its protein expression and MIB-1 index as a proliferative marker in canine mammary tumors. In the present study, a total of 20 cases were examined, among which there were 5 malignant mixed tumors, 4 mammary gland adenocarcinomas, 1 papillary adenocarcinoma, 8 benign mixed tumors and 2 mammary gland adenomas. Positive immunostaining for p53 with PAb240 antibody was found in 2 benign (20%) and 3 malignant...


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