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Impact of Micellar Vehicles on in situ Intestinal Absorption Properties of Beta-Lapachone in Rats
SoungBaekJang, DongjuKim, SeongYeonKim, ChangheePark, JiHoonJeong, Hyo-JeongKuh, JaehwiLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.1 2 9-13 (5 pages)
the in situ permeability of b-lap in all intestinal segments tested although the mixed micellar formulation was more effective in increasing the intestinal absorption of b-lap. The permeability of b-lap was greatest in the large intestinal segments. Compared with SLS micelles, the effective permeability coefficient values measured with mixed micelles were 5- to 23-fold higher depending on the intestinal segment. Our data suggest that b-lap should be delivered to the large intestine using a mixed... -
Intestinal Absorption of Fibrinolytic and Proteolytic Lumbrokinase Extracted from Earthworm, Eisenia andrei
XiangMeiYan, Chung-HyoKim, ChulKyuLee, JangSikShin, IlHwanCho, UyDongSohn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.2 2 71-75 (5 pages)
To investigate the intestinal absorption of a fibrinolytic and proteolytic lumbrokinase extracted from Eisenia andrei, we used rat everted gut sacs and an in situ closed-loop recirculation method. We extracted lumbrokinase from Eisenia andrei, and then raised polyclonal antibody against lumbrokinase. Fibrinolytic activity and proteolytic activity in the serosal side of rat everted gut sacs incubated with lumbrokinase showed dose- and time-dependent patterns. Immunological results obtained by... -
Effect of High-Molecular-Weight Poly-$gamma$-Glutamic Acid from Bacillus subtilis (chungkookjang) on Ca Solubility and Intestinal Absorption
PARK. CHUNG, CHOI. YOON-HO, SHIN. HYUN-JIN, POO. HARYOUNG, SONG. JAE JUN, KIM. CHUL-JOONG, SUNG. MOON-HEE 한국미생물생명공학회 Journal of microbiology and biotechnology 4 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2005, Vol.15 No.4 855-858 (4 pages)
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Effects of Furanocoumarins in Kampo Extract-Based Medicines on Rat Intestinal Absorption of CYP3A and P-glycoprotein Substrate Drugs In Vivo
Iwanaga. Kazunori, Arimune. Kaori, Miyazaki. Makoto, Shibano. Makio, Taniguchi. Masahiko, Baba. Kimiye, Kakemi. Masawo 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 10 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2012, Vol.35 No.6 1055-1064 (10 pages)
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The Effects of PLGA Microparticles on Intestinal Absorption of P-glycoprotein Substrate Using the Everted Rat Intestinal Sac Model
Derakhshandeh. Katayoun, Hosseinalizadeh. Aidin, Nikmohammadi. Maryam 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 9 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2011, Vol.34 No.11 1989-1997 (9 pages)


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