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전체 선택해제
총 277건 검색
본문검색 결과만 보기
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Effects of resveratrol on the insulin signaling pathway of obese mice
Hyun Ju Hong, Wonyoung Kang, Dong Geon Kim, Dae Ho Lee, Youngjae Lee, Chang-Hoon Han* 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 2호 2 179-185 (7 pages)
compared with the levels in the HF group. In addition, the phosphorylation levels of IRS-1 (Ser636/Ser639), PI-3K p85-subunit α/γ (Tyr467/Tyr199), PDK1 (Ser241), GSK-3α (S21) and GSK-3 (Ser9), which are involved in the insulin signaling pathway, were decreased in the HF group, whereas the levels were restored to normal in the HFR group. Overall, the results show that resveratrol restores the phosphorylation levels of proteins involved in the insulin signaling pathway, which were decreased by... -
Insulin-like growth factor-1 improves diabetic cardiomyopathy through antioxidative and anti-inflammatory processes along with modulation of Akt/GSK-3β signaling in rats
ChengYuWang, XiangDanLiZhiHongHao, DongyuanXu 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.6 7 613-619 (7 pages)
kinase (GSK-3β). IGF-1 treatment, however, attenuated the metabolic abnormalities and myocardial apoptosis, interstitial fibrosis, oxidative stress and inflammation seen in diabetic rats, while also increasing the phosphorylation levels of Akt and GSK-3β. These findings suggest that IGF-1 ameliorates the pathophysiological progress of DCM along with an activation of the Akt/GSK-3β signaling pathway. Our findings suggest that IGF-1 could be a potential therapeutic choice for controlling DCM. -
Nucleolar GTPase NOG-1 Regulates Development, Fat Storage, and Longevity through Insulin/IGF Signaling in C. elegans
Kim. Young-Il, Bandyopadhyay. Jaya, Cho. Injeong, Lee. Juyeon, Park. Dae Ho, Cho. Jeong Hoon 한국분자세포생물학회 Molecules and cells 7 Pages
한국분자세포생물학회 Molecules and cells 2014, Vol.37 No.1 51-57 (7 pages)
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Involvement of Phosphatidylinositol 3-Kinase in the Insulin Signaling in Preimplantation Mouse Embryos
Gye. Myung-Chan, Nah. Hee-Young, Kim. Moon-Kyoo 한국발생생물학회 발생과 생식 7 Pages
한국발생생물학회 발생과 생식 2000, Vol.4 No.1 29-35 (7 pages)
A phosphatidylinositol 3-kinase (PI3K)는 인슐린 신호전달의 상위구성 요소로 다양한 세포에서 단백질합성을 촉진한다. PI3K와 하위의 mammalian target of rapamycin (mTOR)가 착상전 생쥐 배아의 인슐린 신호전달에 관여하고 있는지의 여부를 조사하고자 하였다. 생쥐의 8-세포기 배아를 인슐린 또는 PI3K및 mTOR의 억제제를 포함한 조건에서 배양하면서 발생율, 할구수, 단백질합성 및 인산화를 조사하였다. 인슐린의 첨가는 포배형성과 부화 등 형태발생을 촉진하며 포배내 평균 할구수, 8-세포기 배아의 단백질 합성과 인산화를... -
Determination of Insulin Signaling Pathways in Hepatocytes
Kim. Sang-Kyum 한국독성학회 Journal of toxicology and public health : an official journal of the Korean Society of Toxicology 14 Pages
한국독성학회 Journal of toxicology and public health : an official journal of the Korean Society of Toxicology 2005, Vol.21 No.3 195-208 (14 pages)
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Identification of Novel Metabolic Proteins Released by Insulin Signaling of the Rat Hypothalmus Using Liquid Chromatography-Mass Spectrometry (LC-MS)
Chin. Chur 대한신경외과학회 Journal of Korean neurosurgical society 5 Pages
대한신경외과학회 Journal of Korean neurosurgical society 2007, Vol.42 No.6 470-474 (5 pages)
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지방세포분화에서 Hibiscus 추출물에 의한 Insulin signaling 억제효과
김진경, 송정훈, Kim. Jin-Kyung, Song. Jeong-Hoon 대한동의생리학회 동의생리병리학회지 7 Pages
대한동의생리학회 동의생리병리학회지 2007, Vol.21 No.1 86-92 (7 pages)
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Anticarcinogenic effect of quercetin by inhibition of insulin-like growth factor (IGF)-1 signaling in mouse skin cancer
Jung. Minjeong, Bu. So Young, Tak. Ka-Hee, Park. Jeong-Eun, Kim. Eunjung 한국영양학회 Nutrition research and practice 7 Pages
한국영양학회 Nutrition research and practice 2013, Vol.7 No.6 439-445 (7 pages)
