학지사 뉴논문

총 2,451건 검색

본문검색 결과만 보기

정확도순

최신순

등재순

발행기간

전체
최근 1년
최근 3년
직접입력

적용하기

본문검색

포함

제외

10개씩

91.

Efficacy of horse chestnut leaf extract ALH-L1005 as a matrix metalloproteinase inhibitor in ligature-induced periodontitis in canine model

Se Eun Kim, Tae Hyun Kim, Shin Ae Park, Won Tae Kim, Young Woo Park, Jae Sang Ahn, Manbok Jeong, Min-Young Kim, Kangmoon Seo 대한수의학회 Journal of Veterinary Science 7 Pages

대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 2호 15 245-251 (7 pages)

Se Eun Kim, Tae Hyun Kim, Shin Ae Park, Won Tae Kim, Young Woo Park, Jae Sang Ahn, Manbok Jeong, Min-Young Kim, Kangmoon Seo 저
...
- 3,000원
traditionally. This study assessed the clinical effect as a MMP inhibitor of horse chestnut leaf extract ALH-L1005 on periodontitis. ALH-L1005 was obtained from horse chestnut leaf and its MMP inhibitory activities estimated. Periodontitis was induced in beagles assigned to 4 groups and medicated for 6 weeks: low dose test (LT; ALH-L1005, 100 mg/kg/day), high dose test (HT; ALH-L1005, 200 mg/kg/day), positive control (PC; doxycycline, 10 mg/kg/day), or negative control (NC; placebo). Before and...
92.

Neuronal maturation in the hippocampal dentate gyrus via chronic oral administration of Artemisa annua extract is independent of cyclooxygenase 2 signaling pathway in diet-induced obesity mouse model

Hye Kyung Baek, Pan Soo Kim, Ji Ae Song, Dong-Hwa Choi, Do Eun Kim, Seung Il Oh, Sang-Kyu Park, Sung-Jo Kim, Ki-Duk Song, In Koo 대한수의학회 Journal of Veterinary Science 9 Pages

대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 2호 1 119-127 (9 pages)

Hye Kyung Baek, Pan Soo Kim, Ji Ae Song, Dong-Hwa Choi, Do Eun Kim, Seung Il Oh, Sang-Kyu Park, Sung-Jo Kim, Ki-Duk Song, In Koo 저
...
- 3,000원
tested the effect of AA in an Alzheimer’s disease model of Caenorhabditis elegans and uncovered a potential benefit. The results show that chronic AA dosing significantly increases neuronal maturation, particularly in the high-fat diet group. This effect was seen in the absence of any changes in COX-2 levels in mice given the same type of food, pointing to the possibility of alternate anti-inflammatory pathways in the stimulation of neurogenesis and neuro-maturation in a background of obesity.
93.

Aristolochia manshuriensis Kom ethyl acetate extract protects against high-fat diet-induced non-alcoholic steatohepatitis by regulating kinase phosphorylation in mouse

Dong Hoon Kwak, Ji-Su Kim, Kyu-Tae Chang, Young-Kug Choo 대한수의학회 Journal of Veterinary Science 9 Pages

대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 3호 3 279-287 (9 pages)

Dong Hoon Kwak, Ji-Su Kim, Kyu-Tae Chang, Young-Kug Choo 저
...
- 3,000원
of extracellular signal-regulated kinase 1/2 (ERK1/2). These results demonstrate that the protective effect of the extract against HFD-induced NASH occurred via reductions in reactive oxygen species production, inflammation suppression, and apoptosis related to the suppression of JNK1/2 activation and increased ERK1/2 phosphorylation. Taken together, these results indicate that that ethyl acetate extract of AMK has potential therapeutic effects in the HFD-induced NASH mouse model.
94.

Hematoporphyrin monomethyl ether combined with He?Ne laser irradiation-induced apoptosis in canine breast cancer cells through the mitochondrial pathway

Huatao Li, Jinjin Tong, Jun Bao, Damu Tang, Wenru Tian, Yun Liu 대한수의학회 Journal of Veterinary Science 8 Pages

대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 2호 13 235-242 (8 pages)

Huatao Li, Jinjin Tong, Jun Bao, Damu Tang, Wenru Tian, Yun Liu 저
...
- 3,000원
is a novel and promising photodynamic therapy (PDT)-induced apoptosis that can be applied in vitro on canine breast cancer cells. However, the exact pathway responsible for HMME-PDT in canine breast cancer cells remains unknown. CHMm cells morphology and apoptosis were analyzed using optical microscope, terminal deoxynucleotidyl transferase dUTP nick end labeling fluorescein staining and DNA ladder assays. Apoptotic pathway was further confirmed by Real-time-polymerase chain reaction and Western...
95.

Gap junction blockage promotes cadmium-induced apoptosis in BRL 3A derived from Buffalo rat liver cells

Di Hu, Hui Zou, Tao Han, Junze Xie, Nannan Dai, Liling Zhuo, Jianhong Gu, Jianchun Bian, Yan Yuan, Xuezhong Liu, Zongping Liu 대한수의학회 Journal of Veterinary Science 8 Pages

대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 1호 8 63-70 (8 pages)

Di Hu, Hui Zou, Tao Han, Junze Xie, Nannan Dai, Liling Zhuo, Jianhong Gu, Jianchun Bian, Yan Yuan, Xuezhong Liu, Zongping Liu 저
...
- 3,000원
induced apoptosis, involving changes in expression of Bax, Bcl-2, caspase-3 and the mitochondrial transmembrane electrical potential (Δψm). Additionally, GA was found to enhance ERK and p38 activation during Cd-induced activation of mitogen-activated protein kinases, but had no significant effect on JNK activation. Our results indicated the apoptosis-related proteins and the ERK and p38 signaling pathways may participate in gap junction blockage promoting Cd-induced apoptosis in BRL 3A cells.
96.

Agmatine protection against chlorpromazine-induced forebrain cortex injury in rats

Bratislav Dejanovic, Ivana Stevanovic, Milica Ninkovic, Ivana Stojanovic, Irena Lavrnja, Tatjana Radicevic, Milos Pavlovic 대한수의학회 Journal of Veterinary Science 9 Pages

대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 1호 7 53-61 (9 pages)

Bratislav Dejanovic, Ivana Stevanovic, Milica Ninkovic, Ivana Stojanovic, Irena Lavrnja, Tatjana Radicevic, Milos Pavlovic 저
...
- 3,000원
to investigate whether agmatine (AGM) provides protection against oxidative stress induced by treatment with chlorpromazine (CPZ) in Wistar rats. In addition, the role of reactive oxygen species and efficiency of antioxidant protection in the brain homogenates of forebrain cortexes prepared 48 h after treatment were investigated. Chlorpromazine was applied intraperitoneally (i.p.) in single dose of 38.7 mg/kg body weight (BW) The second group was treated with both CPZ and AGM (75 mg/kg BW). The...
97.

Time-course changes in the expression levels of miR-122, -155, and -21 as markers of liver cell damage, inflammation, and regeneration in acetaminophen-induced liver injury in rats

Hyun-Kyu Park, Woori Jo, Hyun-Ji Choi, Sungwoong Jang, Jae-Eun Ryu, Hyo-Ju Lee, Hyojin Lee, Hyejin Kim, Eun-Sil Yu, Woo-Chan Son 대한수의학회 Journal of Veterinary Science 7 Pages

대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 1호 6 45-51 (7 pages)

Hyun-Kyu Park, Woori Jo, Hyun-Ji Choi, Sungwoong Jang, Jae-Eun Ryu, Hyo-Ju Lee, Hyojin Lee, Hyejin Kim, Eun-Sil Yu, Woo-Chan Son 저
...
- 3,000원
Drug-induced liver injury (DILI) is a significant threat to patient health and a major concern during drug development. Recently, multiple circulating microRNAs (miRNAs) have been reported to be potential biomarkers for DILI. To adapt and validate miRNAs for clinical use, we investigated the time-course changes in miR-122 expression levels in an acetaminophen-induced liver injury model in rats. In addition, miR-155 and miR-21 were evaluated as makers of inflammation and regeneration,...
98.

Stress and pain response after oligofructose induced-lameness in dairy heifers

Hedie A. Bustamante, Alfredo R. Rodr?guez, Daniel E. Herzberg, Marianne P. Werner 대한수의학회 Journal of Veterinary Science 7 Pages

대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 4호 3 405-411 (7 pages)

Hedie A. Bustamante, Alfredo R. Rodr?guez, Daniel E. Herzberg, Marianne P. Werner 저
...
- 3,000원
of several pain and stress biomarkers after oligofructose-induced lameness in dairy heifers. Lameness was induced using an oligofructose overload model in 12 non-pregnant heifers. Clinical parameters and blood samples were obtained at 48 and 24 h and at 6, 12, 24, 36 and 48 h after induction of lameness. Clinical parameters included heart rate, respiratory rate, ruminal frequency and lameness score. Plasma biomarkers included cortisol, haptoglobin, norepinephrine, beta-endorphin and substance P....
99.

Anti-adipogenic effect of Artemisia annua in diet-induced-obesity mice model

Hye Kyung Baek, Hyeji Shim, Hyunmook Lim, Minju Shim, Chul-Kyu Kim, Sang-Kyu Park, Yong Seok Lee, Ki-Duk Song, Sung-Jo Kim, Sun 대한수의학회 Journal of Veterinary Science 8 Pages

대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 4호 1 389-396 (8 pages)

Hye Kyung Baek, Hyeji Shim, Hyunmook Lim, Minju Shim, Chul-Kyu Kim, Sang-Kyu Park, Yong Seok Lee, Ki-Duk Song, Sung-Jo Kim, Sun 저
...
- 3,000원
developing countries. Currently, anti-obesity drugs originating from natural products are being investigated for their potential to overcome adverse effects associated with chemical drugs. Artemisinic acid, which was isolated from the well-known anti-malaria herb Artemisia annua (AA) L., was recently shown to possess anti-adipogenic effects in vitro. However, the anti-adipogenic effects of AA in animal models have not yet been investigated. Therefore, we conducted daily oral administration with...
100.

Osteogenic potential of mesenchymal cells derived from canine umbilical cord matrix co-cultured with platelet-rich plasma and demineralized bone matrix

Talita F.B. Souza, Silmara S. Sakamoto, Gabriel T.N.M. Ferreira, Roberto Gameiro, Marcia Marinho, Alexandre L. de Andrade, Terez 대한수의학회 Journal of Veterinary Science 4 Pages

대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 3호 17 381-384 (4 pages)

Talita F.B. Souza, Silmara S. Sakamoto, Gabriel T.N.M. Ferreira, Roberto Gameiro, Marcia Marinho, Alexandre L. de Andrade, Terez 저
...
- 1,500원
osteogenic differentiation. Osteoblastic differentiation followed by mineralized bone matrix production was found to be significantly higher (p ＜ 0.05) when MSCs were associated with PRP/DBM in culture after 14–21-days of induction. Osteopontin and osteocalcin gene expression were significantly superior (p ＜ 0.05) under the same culture conditions after 21 days of observation. In conclusion, addition of PRP to DBM co-cultured with MSCs successfully induced osteogenesis in vitro.

한주간 이슈검색어