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Effects of Proinflammatory Cytokines and Natural Products on Mucin Release from Cultured Hamster Tracheal Surface Epithelial Cells
JiSunPark, HyoungSooKim, JeongHoSeok, GangMinHur, JongSunPark, UnKyoSeo, ChoongJaeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.6 6 329-334 (6 pages)
for 30 min in the presence of varying concentrations of each agent to assess the effects on 3H-mucin release. The results were as follows: TNF-alpha, CTMA and LPD increased mucin release at the highest concentration, but IL-1beta did not. We conclude that CTMA and LPD can stimulate mucin release by directly acting on airway mucin-secreting cells, and suggest that these agents should be further investigated for the possible use as mild expectorants during the treatment of chronic airway diseases. -
Effects of p-Chlorophenylalanine on the Synthesis of Pancreatic Amylase in Rats
HyeokYilKwon, WonSikEum, HyunWooJang, YunLyulLee, HyoungJinPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.2 7 129-135 (7 pages)
rats, indicating that the inhibitory effect of PCPA on the synthesis of pancreatic amylase was mainly regulated at a step prior to translation. It was also revealed in SDS-polyacrylamide gel electrophoresis that the qualitative change of amylase was induced by PCPA. The 54 KDa amylase band seems to be degraded into small molecular weight protein bands in PCPA-treated rats, suggesting that the PCPA- induced decrease of amylase may be partly attributed to the degradation of synthesized amylase. -
Increased Activity of Large Conductance Ca2+-Activated K+ Channels in Negatively-Charged Lipid Membranes
JinBongParkPanDongRyu 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 15 529-539 (11 pages)
were tested by analyzing the activity of single large conductance Ca2-activated K (maxi K) channel from rat skeletal muscle. The conductances and open-state probability (Po) of single maxi K channels were compared in three types of planar lipid bilayers formed from a neutral phosphatidylethanolamine (PE) or two negatively-charged phospholipids, phosphatidylserine (PS) and phosphatidylinositol (PI). Under symmetrical KCl concentrations (3∼1,000 mM), single channel conductances of... -
Combination of Electroconvulsive Therapy and Clozapine in Treatment-Resistant Schizophrenia
Jung Hyun Kim, Tak Youn, Jun Gwon Choi, Seong Hoon Jeong, Hee Yeon Jung, Yong Sik Kim, In Won Chung 대한신경정신의학회 Psychiatry Investigation 7 Pages
대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 13 829-835 (7 pages)
during five years of pre-determined period were recruited from Electronic Medical Record. Clinical effects of acute ECT on psychotic symptoms were investigated. We also tried to identify predictive variables requiring maintenance treatment of ECT. Results_Fourteen patients received ECT and clozapine and sixteen were treated with clozapine alone. In the ECT group, which could be refined as clozapine-resistance, PANSS total score was significantly reduced by 19.0±9.9 points, corresponding to a... -
Cyproheptadine Augmentation of Haloperidol in Chronic Schizophrenic Patients : A Double-Blind Placebo-Controlled Study
Hong Shick Lee, Jin Hak Kim, Young Moon Lee, Eun Sun Han, Man Kwon Kim, Byung Hoon Oh, Sung Kil Min Kae Joon Yoo, Ho Young Lee 대한신경정신의학회 신경정신의학 11 Pages
대한신경정신의학회 신경정신의학 1994, 제 33권 제 1호 23 262-272 (11 pages)
40명의 만성정신분열증 환자를 대상으로 Haloperdiol에 대한 Cyproheptadine 병용치료 효 과를 검중하기 위하여 6주간의 위약ᅳ대조,이중맹검 연구를 시행하였다. 6주간의 이중맹검 Cyproheptadine 병용치료는 양성 및 음성증상 모두에서 임상적인 중상의 호전을 보였으나 위약과 Haloperidol이 병용 투여된 대조군과 비교한 임상적 정신증상에서는 두군 간의 유의한 통계적 차이는 보이지 않았다. 그러나 Cyproheptadine 병용치료는 대조군에 비해 추체외로 증상의 유의한 감소를 보임으로써 항정신병 약물의 비정형적인 특성이... -
Inhibition of Human Neutrophil Elastase by NSAIDs and Inhibitors, and Molecular Pharmacological Mechanism of the Inhibition
강구일(Koo-il Kang), 김우미(Woo Mi Kim), 홍인식(In Sik Hong), 이무상(Moo Sang Lee) 대한약리학회 대한약리학잡지 8 Pages
대한약리학회 대한약리학잡지 1996, 제 32권 제 3호 14 425-432 (8 pages)
Frequencies and contours in the Raman spectra of various conditions of human neutrophil elastase undergo drastic changes upon partial removal and/or reconstitution of calcium and zinc ions. The metal ion content dependent activities and change of the contour of the Raman spectrogram suggest us that the mechanism of action of a chelator or chelator-like agents on neutrophil elastase may be related to the conformational change at/or near the active site, especially -C=O radical or -COOH radical. -
Vertical augmentation using the mandibular body bone for repair of failed implants: a case report
Da-Nee Jeon, Han-Kyul Park, Yong-Deok Kim 대한치과이식임플란트학회 Journal of Dental Implant Research 5 Pages
대한치과이식임플란트학회 Journal of Dental Implant Research 2015, 제 34권 2호 2 41-45 (5 pages)
An implant may fail due to insufficient osseointegration between the supporting bone and the implant. Surgical removal of a failed implant is unavoidable with severe bone loss and an infectious state. In this case, a wide-ranging bone graft surgery is needed. The mandibular body bone (MBB) is an autogenous bone that could be a donor site for an alveolar bone graft. An MBB graft is easy, simple, and safe. This study reports a successful bone graft that used only MBB to repair a failed implant... -
A retrospective study of Snucone implants: Clinical and radiographic results
Sunam Yang, Hyunsu Lee, Hyeongi Yi, Dongwoo Lee, Heesang Lee, Hongjae Kwak, Panjun Kim, Kiwook Song, Woonheuk Jung 대한치과이식임플란트학회 Journal of Dental Implant Research 5 Pages
대한치과이식임플란트학회 Journal of Dental Implant Research 2015, 제 34권 1호 4 22-26 (5 pages)
As osseointegration implant has become one of the important treatment methods to treat partially and fully edentulous patients, various implant systems have been developed by several manufacturers. However, there is few studies on Korean implant when compared to foreign implant. And it is true that people vaguely disbelieve Korean implant relatively. Therefore, these authors have analyzed clinical results of 5 years about 41 implants targeting the total 23 patients who had AF fixtures (Snucone,... -
The long-term clinical stability of implants placed with ridge splitting technique
Jae-Min Yoon, Young-taek Kim, Yong-ju Jang, Jung-chul Park, Seong-ho Choi, Kyoo-sung Cho, Chang-sung Kim 대한치과이식임플란트학회 Journal of Dental Implant Research 8 Pages
대한치과이식임플란트학회 Journal of Dental Implant Research 2011, 제 30권 1호 1 1-8 (8 pages)
period was 4.2 °æ 2.1 years. During the follow up, the cumulative survival rate of implants was 100%. The mean marginal bone loss of implants was 1.57 °æ 1.44 mm at the mesial side and 1.42 °æ 1.48 mm at the distal side. In non-submerged implants, the mean marginal bone loss was 1.17 mm and 0.70 mm on the mesial and the distal sides, respectively. In submerged implants, the loss was 1.74 mm and 1.59 mm on the mesial and the distal sides, respectively. The difference between the two groups... -
A new crestal approach for sinus floor elevation: Case reports
Young-Kyun Kim, Young-Ku Heo, Pil-Young Yun, Hyo-Jung Lee 대한치과이식임플란트학회 Journal of Dental Implant Research 7 Pages
대한치과이식임플란트학회 Journal of Dental Implant Research 2009, 제 28권 1호 5 41-47 (7 pages)
The posterior maxilla often presents specific problems for placement of dental implants. Frequently poor bone quality with inadequate bone volume has rendered long-term success rates for implants1). To overcome this situation, usually sinus floor elevation was carried out through the lateral approach technique or crestal approach, so called, osteotome method. The osteotome technique, first described in 1994, has been known for the primary advantage of being less invasive than lateral window...


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