자료유형
발행기관
- 대한생리학회-대한약리학회(203)
- 대한생리학회(54)
- 대한약리학회(35)
- 대한신경정신의학회(24)
- 대한수의학회(13)
- 대한약학회(4)
- 대한신경계작업치료학회(2)
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- 한국생명과학회(2)
- 경락경혈학회(1)
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- 대한동의생리학회(1)
- 대한본초학회(1)
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간행물
- THE KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY(203)
- 대한생리학회지(54)
- 대한약리학잡지(35)
- 신경정신의학(24)
- JOURNAL OF VETERINARY SCIENCE(10)
- ARCHIVES OF PHARMACAL RESEARCH : A PUBLICATION OF THE PHARMACEUTICAL SOCIETY OF KOREA(2)
- KOREAN JOURNAL OF VETERINARY RESEARCH(구 대한수의학회지)(2)
- 생명과학회지(2)
- 약학회지(2)
- 재활치료과학(2)
- AUDIOLOGY AND SPEECH RESEARCH(1)
- INTERNATIONAL JOURNAL OF MARITIME INFORMATION AND COMMUNICATION SCIENCES(1)
- JOURNAL OF GINSENG RESEARCH(1)
- JOURNAL OF KOREAN BIOLOGICAL NURSING SCIENCE(1)
- JOURNAL OF SEMICONDUCTOR TECHNOLOGY AND SCIENCE(1)
- PHYSICAL THERAPY REHABILITATION SCIENCE(1)
- 대한경락경혈학회지(1)
- 대한본초학회지(1)
- 대한수의학회 학술대회발표집(1)
- 대한치과보존학회지(1)
- 동의생리병리학회지(1)
- 전기전자재료학회지= THE JOURNAL OF THE KOREAN INSTITUTE OF ELECTRICAL AND ELECTRONIC MATERIAL ENGINEERS(1)
- 전자공학회논문지. JOURNAL OF THE INSTITUTE OF ELECTRONICS ENGINEERS OF KOREA. SC, 시스템 및 제어(1)
- 정보처리학회논문지. KIPS TRANSACTIONS ON SOFTWARE AND DATA ENGINEERING. 소프트웨어 및 데이터 공학(1)
- 한국농화학회지(1)
- 한국명상학회지(1)
- 한국보건기초의학회지(1)
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The Effect of External Divalent Cations on Intestinal Pacemaking Activity
ByungJooKim, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.4 3 203-208 (6 pages)
Electrical rhythmicity in the gastrointestinal (GI) muscles is generated by pacemaker cells, known as interstitial cells of Cajal (ICC). In the present study, we investigated the effect of external divalent cations on pacemaking activity in cultured ICC from murine small intestine by using whole-cell patch clamp techniques. ICC generated pacemaker currents under a voltage clamp or electrical pacemaker potentials under a current clamp, and showed a mean amplitude of 500⁑50 pA or... -
N-methyl-D-aspartate (NMDA) and Non-NMDA Receptors are Involved in the Production and Maintenance of Nociceptive Responses by Intraplantar Injection of Bee Venom and Melittin in the Rat
JaeHwaKim, HongKeeShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.3 8 179-185 (7 pages)
Whole bee venom (WBV) and its major component, melittin, have been reported to induce long-lasting spontaneous flinchings and hyperalgesia. The current study was designed to elucidate the peripheral and spinal mechanisms of N-methyl-D-aspartate (NMDA) and non-NMDA receptors by which intraplantar (i.pl.) injection of WBV and melittin induced nociceptive responses. Changes in mechanical threshold and flinching behaviors were measured after the injection of WBV (0.04 mg or 0.1 mg/paw) and melittin... -
Effects of a δ-opioid Agonist on the Brainstem Vestibular Nuclear Neuronal Activity of Rats
Tae-SunKim, MeiHuang, Myung-JooJang, Han-SeongJeong, Jong-SeongPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.3 1 137-142 (6 pages)
This study was undertaken to investigate the effects of [D-Ala2, D-Leu5]-enkephalin (DADLE) on the spontaneous activity of medial vestibular nuclear neurons of the rat. Sprague-Dawley rats, aged 14 to 16 days, were anesthetized with ether and decapitated. After enzymatic digestion, the brain stem portion of medial vestibular nuclear neuron was obtained by micropunching. The dissociated neurons were transferred to a recording chamber mounted on an inverted microscope, and spontaneous action... -
Regulation of L-type Calcium Channel Current by Somatostatin in Guinea-Pig Gastric Myocytes
YoungChulKim, JaeHoonSim, SangJinLee, TongMookKang, SungJoonKim, SeungRyulKim, SeiJinYoun, SangJeonLee, Wen-XieXu6, InsukSo, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.2 5 103-108 (6 pages)
To study the direct effect of somatostatin (SS) on calcium channel current (IBa) in guinea-pig gastric myocytes, IBa was recorded by using whole-cell patch clamp technique in single smooth muscle cells. Nicardipine (1μM), a L-type Ca2+ channel blocker, inhibited IBa by 98⁑1.9% (n=5), however IBa was decreased in a reversible manner by application of SS. The peak IBa at 0 mV were decreased to 95⁑1.1, 92⁑1.9, 82⁑4.0, 66⁑5.8, 10⁑2.9% at 1010, 109,... -
Differential Effects of Typical and Atypical Antipsychotics on MK- 801-induced EEG Changes in Rats
JeeSookKwon, KiMinKim, SuMinChang, Choong-YoungKim, TaiHoChung, Byung-JuChoi, MaanGeeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.1 3 17-22 (6 pages)
We examined whether the abnormal EEG state by NMDA receptor blocker MK-801 can be reversed by typical and atypical antipsychotics differentially by comparing their spectral profiles after drug treatment in rats. The spectral profiles produced by typical antipsychotics chlorpromazine (5 mg/kg, i.p.) and haloperidol (0.5 mg/kg, i.p.) were differ from that by atypical antipsychotic clozapine (5 mg/kg, i.p.) in the rats treated with or without MK-801 treatment (0.2 mg/kg, i.p.) which produce... -
Effects of PCB Congeners in Rodent Neuronal Cells in Culture
Sun-YoungKimJae-HoYang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.1 2 9-16 (8 pages)
We attempted to analyze the mechanism of polychlorinated biphenyl (PCB)-induced neurotoxicity and identify the target molecules in the neuronal cells for PCBs.Since the developing neuron is particularly sensitive to PCB-induced neurotoxicity, we isolated cerebellar granule cells derived from 7-day old Sprague Dawley (SD) rats and grew cells in culture for additional 7 days to mimic PND-14 conditions. Only non-coplanar PCBs at a high dose showed a significant increase of total protein kinase C... -
Effects of NMDA, AMPA and Kainate on the Release of Acetylcholine in Rat Hippocampal and Striatal Slices
DoKyungKim, SeoulLee, KyuYongJung, Jong-KeunKim, BongKyuChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.6 2 301-306 (6 pages)
This study examined the effects of N-methyl-D-aspartate (NMDA), α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) and kainate on basal and electrically-evoked release of acetylcholine (ACh) from the rat hippocampal and striatal slices which were preincubated with [3H]choline. Unexpectedly, the basal and evoked ACh release were not affected at all by the treatment with NMDA (3∼100μM), AMPA (1∼100μM) or kainate (1∼100μM) in hippocampal slices. However, in striatal slices, under... -
Effect of Fluoxetine on the Induction of Long-term Potentiation in Rat Frontal Cortex
Hwang-SooKim, Hyun-SokKim, SangJuneHahn, Myung-JunKim, ShinHeeYoon, Yang-HyeokJo, Myung-SukKim, Duck-JooRhie 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.6 1 295-300 (6 pages)
Serotonin (5-hydroxytroptamine, 5-HT) has been shown to affect the induction of long-term potentiation (LTP) in the cortex such as the hippocampus, the visual cortex and the prefrontal cortex. Fluoxetine, as a selective serotonin reuptake inhibitor, is used in the management of a wide variety of psychological diseases. To study the effect of fluoxetine on the induction of LTP, we recorded the field potential in layer II/III of the frontal cortex from 3-wk-old. LTP was induced in horizontal input... -
Comparative Study on the Nociceptive Responses Induced by Whole Bee Venom and Melittin
HongKeeShin, KyungHeeLee, SeoEunLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.5 7 281-288 (8 pages)
The present study was undertaken to confirm whether melittin, a major constituent of whole bee venom (WBV), had the ability to produce the same nociceptive responses as those induced by WBV. In the behavioral experiment, changes in mechanical threshold, flinching behaviors and paw thickness (edema) were measured after intraplantar (i.pl.) injection of WBV (0.1 mg & 0.3 mg/paw) and melittin (0.05 mg & 0.15 mg/paw), and intrathecal (i.t.) injection of melittin (6μg). Also studied were the... -
Characterization of Acetylcholine-induced Currents in Male Rat Pelvic Ganglion Neurons
Joong-HyunPark, Kyu-SangPark, Seung-KyuCha, Keon-IlLee, Min-JungKim, Jong-YeonPark, InDeokKong, Joong-WooLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.4 8 219-226 (8 pages)
α-methyllycaconitine, and dihydro-β-erythroidine, which are known as potent and sensitive blockers for α7 or α4β2 nAChRs, below micromolar concentrations showed negligible effect. RT-PCR analysis revealed that α3 and β4 subunits were predominantly expressed in MPG neurons. We suggest that MPG neurons have nAChRs containing α3 and β4 subunits, and that their activation induces fast inward currents, possibly mediating the excitatory synaptic transmission in pelvic autonomic ganglia.


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