자료유형
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- 대한생리학회-대한약리학회(158)
- 대한생리학회(53)
- 대한약리학회(42)
- 대한수의학회(17)
- 한국생약학회(4)
- 대한약학회(2)
- 물리치료재활과학회(2)
- 한국기초간호학회(2)
- 고려인삼학회(1)
- 대한신경정신의학회(1)
- 대한한의학회(1)
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- 한국탄소학회(1)
- 한방비만학회(1)
간행물
- THE KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY(158)
- 대한생리학회지(53)
- 대한약리학잡지(42)
- KOREAN JOURNAL OF VETERINARY RESEARCH(구 대한수의학회지)(11)
- JOURNAL OF VETERINARY SCIENCE(5)
- 생약학회지(4)
- ARCHIVES OF PHARMACAL RESEARCH : A PUBLICATION OF THE PHARMACEUTICAL SOCIETY OF KOREA(2)
- JOURNAL OF KOREAN BIOLOGICAL NURSING SCIENCE(2)
- PHYSICAL THERAPY REHABILITATION SCIENCE(2)
- CARBON LETTERS(1)
- JOURNAL OF GINSENG RESEARCH(1)
- THE JOURNAL OF APPLIED PHARMACOLOGY : THE OFFICIAL JOURNAL OF THE KOREAN SOCIETY OF APPLIED PHARMACO(1)
- 대한수의학회 학술대회발표집(1)
- 대한한방비만학회지(1)
- 대한한의학회지(1)
- 대한흉부외과학회지(1)
- 신경정신의학(1)
- 한국보건기초의학회지(1)
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총 288건 검색
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Differential Effects of Nitric Oxide Synthase Inhibitors in Rats
Jun-HeeLee, ChangYellShin, BongSuKang, JiHoonJeong, KyeongBumChoi, YoungSilMin, JinHakKim, InHoiHuh, UyDongSohn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.2 3 99-104 (6 pages)
We investigated the action of NOS inhibitors on NOS in rats. Both of nitric oxide synthase inhibitors, NG-monomethyl-L-arginine (L-NMMA, 3μM) or NG-nitro-L-arginine methylester (L-NAME, 30μM), augmented phenylephrine (PE, 107 M)-induced contraction which was inhibited by acetylcholine (ACh) in rat thoracic aorta. This augmentation by L-NAME or L-NMMA was attenuated with the treatment of NO precursor, arginine. ACh, however, decreased the augmentation induced by L-NMMA, but not by... -
Effects of Calcium Channel Blockers on Porcine Cardiac and Coronary Arterial Function in Ischemia-Reperfusion
YungHongBaik, HyunKook, SunHeePark, SeongJooJeong, DongYoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.6 7 587-595 (9 pages)
NI-RCA. Endothelium-dependent relaxation by calcium ionophore A23187 was inhibited in I-RCA and VI-RCA, and recovered in NI-RCA. Cyclic GMP contents were decreased in I-RCA group alone. Electrical field stimulation in C-RCA produced transient and frequency-dependent contractions and at 50 Hz caused biphasic contractions. The transient contractions were not affected by pretreatment with phentolamine and atropine, but the biphasic contraction was altered by the pretreatment. Both contractions were... -
Effects of Protein Kinase C Modulation on Hepatic Hemodynamics and Glucoregulation
JoongWooLee, InDeokKong, KyuSangPark, HaeSookChung, JamesPFilkins 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.6 5 571-578 (8 pages)
This study evaluated the effects of PKC activation using phorbol 12-myristate 13-acetate (PMA) and PKC inhibition using the isoquinoline sulfomide derivative H-7 on hemodynamics and glucoregulation in the isolated perfused rat liver. Livers were isolated from fed male Holtzman rats and perfused with Krebs Ringer bicarbonate solution under a constant flow of 50 ml/min at 35oC. Portal vein pressure, glucose and lactate concentrations in the medium and oxygen consumption rates were continuously... -
Enhanced Expression of Inducible Nitric Oxide Synthase May Be Responsible for Altered Vascular Reactivity in Streptozotocin-induced Diabetic Rats
JaeKwonJang, YoungJinKang, HanGeukSeo, SookJaeSeo, KiChurlChang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.4 2 375-382 (8 pages)
that STZ-treated rats increased the maximal contractile response of the aorta to phenylephrine (PE), and high K, while the sensitivity remained unaltered. Endothelium-dependent relaxation, but not SNP-mediated relaxation, was reduced in STZ-treated rats. Plasma nitrite/nitrates are significantly increased in STZ-treated rats compared to controls. The malondialdehyde (MDA) contents of liver, serum, and aorta of diabetic rats were also significantly increased. Furthermore, nitrotyrosine, a... -
Characteristics of Hypoxic Pulmonary Vasoconstriction of the Rat Study by the Vessel Size and Location in the Lung
Sang-JinLeeKiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 10 321-328 (8 pages)
Pulmonary blood vessels with diameters of 200∼400 μm produce considerably more force in response to vasoconstrictor drugs than those which are either smaller or larger. We have therefore investigated whether or not hypoxic pulmonary vasoconstriction (HPV) is more powerful in vessels of these diameters. We have also looked at the possibility that vessels from different regions of the lung respond differently. To do this we have grouped vessels according to their location within the lung as... -
Evidence for Adenosine Triphosphate (ATP) as an Excitatory Neurotransmitter in Guinea-Pig Gastric Antrum
TongMookKang, WenxieXu, SungJoonKim, SeungCheolAhn, YoungChulKim, InsukSo, MyoungKyuPark, Dae-YongUhm, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.2 6 165-174 (10 pages)
We explore the question of whether adenosine 5'-triphosphate (ATP) acts as an excitatory neurotransmitter in guinea-pig gastric smooth muscle. In an organ bath system, isometric force of the circular smooth muscle of guinea-pig gastric antrum was measured in the presence of atropine and guanethidine. Under electrical field stimulation (EFS) at high frequencies (＞20 Hz), NO-mediated relaxation during EFS was followed by a strong contraction after the cessation of EFS (a... -
Roles of Na+-Ca2+ Exchange in the Negative Force-Frequency Relationship
ChangMannKoSoonJinKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.6 8 715-724 (10 pages)
Frequency-force relationships (FFR) were studied in electrically field stimulated rat left atria (LA) by reducing the stimulation frequency from resting 3 Hz to test frequencies (0.1-1 Hz) for 5 minutes. The twitch amplitudes of LA elicited the typical negative staircases with 3-phased changes: the initial rapid increase, the second decrease and the following plateau at test frequencies. Verapamil (3⁓105 M) pretreatment elicited frequency-dependent suppression of the twitch... -
Moderate Elevation of Extracellular K+ Concentration Induces Vasorelaxation in Isolated Rat, Rabbit and Human Cerebral Arteries Role of Na Pump and Ba-Sensitive Process
DongHoKim, SungJoonKim, SangJinLee, SungJinPark, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.6 7 705-714 (10 pages)
in the rabbits and induced relaxation in the rats and humans. Addition of K (2∼10 mM) to the control solution induced vasorelaxations. These effects were inhibited by the pretreatment with both ouabain (10 ㄍM) and Ba2 (0.1∼0.3 mM) in the rat, but only with ouabain (10 ㄍM) in the rabbit and human. These results suggest that K-induced vasorelaxation occurs via the stimulation of electrogenic Na pump in the rabbit and human MCAs, while in the rat MCAs via the... -
Sensitivity of Rabbit Cerebral Artery to Serotonin is Increased with the Moderate Increase of Extracellular K+
SukHyoSuh, SungJinPark, JaiYoungChoi, JaeHoonSim, YoungChulKim, SungJoonKim, InsukSo, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.6 6 695-703 (9 pages)
6 mM to 12 mM. K-induced relaxation was evoked with the stepwise increment of extracellular K from 0 or 2 mM to 12 mM by 2 mM in basilar arterial rings, which were contracted by histamine. But [K]O elevation from 4 or 6 mM to 12 mM by the stepwise increment evoked no significant relaxation. Basal tension of basilar artery was increased with [K]O elevation from 6 mM to 12 mM by 2 mM steps or by the treatment with ouabain and the increase of basal tension was blocked by...
