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Functional Characterization of ABCB4 Mutations Found in Low Phospholipid-Associated Cholelithiasis (LPAC)
TaeHeeKim, HyoJinPark, JiHaChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.6 8 525-530 (6 pages)
Multidrug resistance 3 (MDR3) is expressed on the canalicular membrane of the hepatocytes and plays an important role in protecting the liver from bile acids. Altered ABCB4 gene expression can lead to a rare hepatic disease, low phospholipid-associated cholelithiasis (LPAC). In this study, we characterized 3 ABCB4 mutations in LPAC patients using various in vitro assay systems. We first measured the ability of each mutant to transport paclitaxel and then the mechanisms by which these mutations... -
Low Levels of after School-Hours Social Interaction and Physical Activity of 5-7 Year Olds
Anita Bundy, Lina Engelen, Geraldine Naughton, Shirley Wyver 환태평양유아교육연구학회 Asia-Pacific journal of research in early childhood education 14 Pages
환태평양유아교육연구학회 Asia-Pacific journal of research in early childhood education 2018, Vol.12 No.2 5 79-92 (14 pages)
As part of a cluster randomized controlled trial (Bundy et al., 2017), the after school-hours activities of 5-7 year old children were recorded by parents and other adult carers on four consecutive weekdays between 3:30pm-7:00pm. Records of time use showed most time was spent indoors in activities involving low levels of physical activity. The most-frequently-recorded activity was screen time, accounting for approximately one quarter of all activities. Higher levels of physical activity were... -
The effects of stacking sequence on the penetration-resistant behaviors of T800 carbon fiber composite plates under low-velocity impact loading
Furqan Ahmad, Jung-Wuk Hong, Heung Soap Choi, Soo-Jin Park, Myung Kyun Park 한국탄소학회 Carbon Letters 9 Pages
한국탄소학회 Carbon Letters 2015, Vol.16 No.2 6 107-115 (9 pages)
Impact damages induced by a low-velocity impact load on carbon fiber reinforced polymer (CFRP) composite plates fabricated with various stacking sequences were studied experimentally. The impact responses of the CFRP composite plates were significantly affected by the laminate stacking sequences. Three types of specimens, specifically quasi-isotropic, unidirectional, and cross-ply, were tested by a constant impact carrying the same impact energy level. An impact load of 3.44 kg, corresponding to... -
동방결절에서 과분극에 의해 활성화되는 내향전류에 대한 Cyclic-GMP의 영향 Effects of Cyclic-GMP on Hyperpolarization-activated inward Current (If) in Sino-atrial Node Cells of Rabbit
유신, 호원경, 엄융의, ShinYoo, Won-KyungHo, YungEEarm 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.6 14 731-739 (9 pages)
The aim of present study is to investigate the effects of cGMP on hyperpolarization activated inward current (If), pacemaker current of the heart, in rabbit sino-atrial node cells using the whole-cell patch clamp technique. When sodium nitroprusside (SNP, 80μM), which is known to activate guanylyl cyclase, was added, If amplitude was increased and its activation was accelerated. However, when If was prestimulated by isopreterenol (ISO, 1μM), SNP reversed the effect of ISO. In the absence of... -
Zero-Crossing 복조기를 위한 $0.5{mu}m$ CMOS FM 라디오 수신기
김성웅, 김영식, Kim. Sung-Woong, Kim. Young-Sik 대한전자공학회 電子工學會論文誌. Journal of the Institute of Electronics Engineers of Korea. SD, 반도체 6 Pages
대한전자공학회 電子工學會論文誌. Journal of the Institute of Electronics Engineers of Korea. SD, 반도체 2010, Vol.47 No.2 100-105 (6 pages)
수신기는 Low-IF 구조를 기초로 설계되었으며, Low-Noise Amplifier (LNA), Down-Conversion Mixer, Phase locked loop (PLL), Low-pass filter (LPF), 비교기를 포함하는 RF/Analog 집적회로로 개발되었다. 측정결과 LNA와 Mixer를 포함하는 RF Block은 23.2dB의 변환 이득과 입력 PldB는 -14dBm였고 전체 잡음지수는 15 dB로 나타났다. IF단 LPF와 비교기를 포함하는 Analog Block은 89dB 이상의 전압 이득을 가지고, IC내부의 레지스터를 제어하여 600KHz에서 1.3MHz까지 100KHz 단위로 Passband 대역를 조절할 수 있도록 설계되었다.... -
The Effects of Abdominal Draw-in Maneuver on Hip, Abdominal Muscle Activation Pattern and Trunk, Pelvic Displacement during One Leg Standing
Jeong-Hoon Lee, Nam-Goo Kang, Byeong-Jin Kim, Jong-Gil Seo, Jae-Seop Oh 한국임상움직임치료학회 한국임상움직임치료학회지 9 Pages
한국임상움직임치료학회 한국임상움직임치료학회지 2021, 제 1권 제 1호 5 35-43 (9 pages)
Background : The one-leg standing (OLS) test is a method of evaluating trunk stability. The transverse abdominis (TrA) is an important muscle that contributes to trunk stability during functional movement through abdominal draw-in maneuver (ADIM). The gluteus medius (Gmed) is also important for functional movement and for stability of the hip joints in the muscles that prevent lateral deviation of the trunk in OLS. During ADIM, the Gmed, TrA and internal oblique (IO) muscles are activated. It... -
Pressure pain threshold and visual analogue scale changes in the high and low energy extracorporeal shock wave
You-Jin Yang, Seung-Joon Lee, Matthew Choi 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2014, 제 3권 제 2호 10 142-147 (6 pages)
Objective: This study aims to investigate high energy and low energy extracorporeal shockwave therapy (ESWT) and which one is more effective for shoulder pain. Design: Single blind randomized controlled trial. Methods: Fifty two subjects with upper trapezius (UT) trigger point (TrP) participated in this study. They were allocated to high energy (n=26) and low energy group (n=26). This study applies ESWT and investigates the changes of pressure pain threshold (PPT) and visual analogue scale...


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