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- 정보처리학회논문지. THE KIPS TRANSACTIONS. PART A. PART A(1)
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Postnatal Changes in Atrial Compliance and Stretch-Induced ANP Secretion in Rabbits
SuhnHeeKim, KyungSunLee, SungZooKim, KyungHwanSeul, KyungWooCho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.5 8 393-401 (9 pages)
To define the postnatal changes in ANP secretion in response to mechanical stretch and atrial compliance, experiments have been done in perfused nonbeating rabbit atria with different ages: 1-day, 1-, 2-, 3-, 4-, and 8-wk-old. In 1-day-old-rabbits, an increase in intraatrial pressure resulted in an increase in atrial volume, which was higher than that in 1-wk-old rabbits. Increases in atrial volume stimulated the secretion of ANP with concomitant translocation of extracellular fluid (ECF) into... -
Enhancement of Cyclosporine-Induced Oxidative Damage of Kidney Mitochondria by Iron
Yoon-YoungJang, Eun-SookHan, Chung-SooLee, Young-KiKim, Jin-HoSong, Yong-KyooShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.6 12 631-640 (10 pages)
The present study investigated the stimulatory effects of iron (or ascorbate) on cyclosporine-induced kidney mitochondrial damage. Damaging effect of 50 μM cyclosporine plus 20 μM Fe2 on mitochondrial lipids and proteins of rat kidney and hyaluronic acid was greater than the summation of oxidizing action of each compound alone, except sulfhydryl oxidation. Cyclosporine and 100 μM ascorbate showed an enhanced damaging effect on lipids but not on proteins. The peroxidative action of... -
Comparative Effects on Secretion of LH, FSH, Prolactin, and Testosterone by Chronic and Direct Hypothalamic Administration of Nonylphenol to Adult Male Rats
Kun-SukPark, Won-CheoulJang, Mee-KyungKim, Hyung-GunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.2 12 215-222 (8 pages)
Nonylphenol (NP) is a widespread environmental pollutant that has been shown to exert both toxic and estrogenic effects on mammalian cells. As the effects of NP on the reproductive system of adult male vertebrates are virtually unknown, we investigated not only the changes of reproductive hormone secretion in serum after chronic exposure to NP but also, in order to identify the site of its action, the reproductive hormone secretion in serum 48 hours after microinfusion of NP within hypothalamic... -
Assessment of Flavin-containing Monooxygenase (FMO) Activity by Determining Urinary Ratio of Theobromine and Caffeine in a Korean Population after Drinking a Cup of Coffee
Woon-GyeChung, , Ju-HeeKang, Hyung-KeunRoh, Kyung-HoonLee, Chang-ShinPark, Young-NamCha, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.2 11 207-213 (7 pages)
To examine individual variation in drug metabolism catalyzed by flavin-containing monooxygenase (FMO), 179 Korean volunteers' urinary molar concentration ratio of theobromine (TB) and caffeine (CA) was determined. Their urine was collected for 1 hr (between 4 and 5 hrs) after they drank a cup of coffee containing 115 mg CA and analyzed by an HPLC system. The lowest TB/CA ratio obtained was 0.40, the highest ratio was 15.17 (38-fold difference), and the median ratio for all subjects was 1.87.... -
Further Characterization of Bombesin Like Immunoreactivities from the Skin of Korean Fire-bellied Toad, Bombina orientalis
HyeokYilKwon, HyungSeoPark, MooHoWon, YunLyulLee, HyoungJinPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.5 12 637-644 (8 pages)
Previously, we have isolated authentic bombesin and another bombesin like peptide named bombesin like immunoreactivity (BLI)-K2 from the skin of Korean fire-bellied toad, Bombina orientalis. In the present study, we have newly purified three heterogeneous forms of BLI named BLI-K3, BLI-K4, and BLI-K5 from side fractions obtained in previous isolation of bombesin like peptide. The BLIs were separated into five peaks on a column of C18 preparative HPLC. Among them, three minor peaks containing... -
Olanzapine을 투여 받은 정신분열병 환자의 체중, 체질량지수, 렙틴, 인슐린, 공복시 혈당의 변화
김양래, 권영준, 박인준, 정희연, 우기민, 조만희 대한신경정신의학회 신경정신의학 7 Pages
대한신경정신의학회 신경정신의학 2001, 제 40권 제 6호 24 1240-1246 (7 pages)
연구목적: 본 연구는 olanzapine의 투여와 관계된 체중증가의 가능한 기전을 규명하기 위하여 시행하였다. 방 법: 정신분열병으로 진단 받고 순천향대학교 천안병원 정신과에 입원 중인 13명의 환자를 대상으로 체중, 체질량 지수(body mass index:BMI), 렙틴(leptin), 인슐린(insulin)과 공복시 혈당(fasting glucose)을 olanzapine 투여전과 투여 후 1주, 2주, 4주, 6주에 측정하였다. 결 과: Olanzapine을 투여 받은 환자는 체중, 체질량 지수, 렙틴, 인슐린, 공복시 혈당이 모두 투여전과 비교하여 의 미있게 증가하였다.... -
Apathy : 개념의 변화와 전망
송후림, 박원명 대한신경정신의학회 신경정신의학 8 Pages
대한신경정신의학회 신경정신의학 2011, 제 50권 제 5호 4 354-361 (8 pages)
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Validity Study of Korean Version of the Schedule for Affective Disorder and SchizophreniaᅳLifetime
Ho Young Lee, Dong Ho Song 대한신경정신의학회 신경정신의학 7 Pages
대한신경정신의학회 신경정신의학 1987, 제 26권 제 3호 22 592-598 (7 pages)
최근에 정신과 영역의 임상 및 연구분야에 있어 서 진단과정상의 낮은 신뢰도와 타당도에 관한 문 제를 해결하려는 움직임이、활발한 것 같다. 이에 대한 방법상의 문제로 진단기준과 정보수 집 과정의 변인이 중요한 원인으로 대두되고 있으 며,연구 진단기준(Research Diagnostic C rite r ia ; RDC) 이나 DSM-M 의 개발은 진단기준의 변인을 조절하려는 노력이고, SADS일생형(S c h e d u le for A ffective D isorder and S chizophrenia - L ife tim e ; SADS-L)과 미국 NIMH가 개발한 진단적 면담검사(Diagnostic Interview...


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