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전체 선택해제
총 332건 검색
본문검색 결과만 보기
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The Mechanism of t-Butylhydroperoxide-Induced Apoptosis in IMR- 32 Human Neuroblastoma Cells
Jung-AeKim, YongSooLee, KeunHuh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 3 19-28 (10 pages)
Apoptosis has been implicated in the pathophysiological mechanisms of various neurodegenerative diseases. In a variety of cell types, oxidative stress has been demonstrated to play an important role in the apoptotic cell death. However, the exact mechanism of oxidative stress-induced apoptosis in neuronal cells is not known. In this study, we induced oxidative stress in IMR-32 human neuroblastoma cells with tert- butylhydroperoxide (TBHP), which was confirmed by significantly reduced... -
Renal Handling of Sodium and Potassium in Cadmium Exposed Rats
YungKyuKimYangSaengPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 12 503-510 (8 pages)
Effects of cadmium exposure on renal Na and K transports were studied in rats. During the course of cadmium treatment (2 mg Cd/kg/day, s.c. injections for 3 weeks) renal tubular transports of Na and K were evaluated by lithium clearance technique. During the early phase (first week) of cadmium treatment, urinary Na excretion decreased drastically and this was due to an increased Na reabsorption both in the proximal and distal nephrons. During the late... -
Ethanol Prevents from Acetaminophen Inducible Hepatic Necrosis by Inhibiting its Metabolic Activation in Mice
Sun-MeeLee, Tai-SoonCho, Young-NamCha 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.2 15 261-269 (9 pages)
large dose of acetaminophen (400 mg/kg). This was evidenced by the normal histological appearances of liver sections and by the lowered serum aminotransferase activities in mice treated with ethanol and acetaminophen together. In the mice treated with acetaminophen alone, along with the hepatic necrosis, the hepatic microsomal aminopyrine N-demethylase activity was decreased. However, co-administration of ethanol prevented this acetaminophen dependent inhibition on the microsomal mixed function... -
Effect of t-butylhydroperoxide on Na+-dependent Glutamate Uptake in Rabbit Brain Synaptosome
HyunJeLeeYongKeunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.4 3 367-376 (10 pages)
The effect of an organic peroxide, t-butylhydroperoxide (t-BHP), on glutamate uptake was studied in synaptosomes prepared from cerebral cortex. t-BHP inhibited the Na+-dependent glutamate uptake with no change in the Na+-independent uptake. This effect of t-BHP was not altered by addition of Ca2+ channel blockers (verapamil, diltiazem and nifedipine) or PLA2 inhibitors (dibucaine, butacaine and quinacrine). However, the effect was prevented by iron chelators (deferoxamine and phenanthroline)... -
Lithium 및 數種 睡眼劑가 家兎 血中酒精濃度에 미치는 影響에 關한 實驗的 研究
金核, 眞鑛建, 李起蘇, 白尙昌 대한신경정신의학회 신경정신의학 12 Pages
대한신경정신의학회 신경정신의학 1972, 제 11권 제 4호 5 243-254 (12 pages)
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항경련제의 부작용ㅡ DiphenyHiydantoin 의 부작용을 중심으로-----
李定均, 曹诛, 哲 대한신경정신의학회 신경정신의학 8 Pages
대한신경정신의학회 신경정신의학 1976, 제 15권 제 1호 7 57-64 (8 pages)
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Lithium이 家兔腦에 미치는 影響에 關한 病理組織學的 硏究
대한신경정신의학회 신경정신의학 1976, 제 15권 제 1호 5 28-44 (17 pages)
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Medazepam 및 Cloxazolam 이 가토혈중 주정 농도에 미치는 영양에 관한 실험적 연구
대한신경정신의학회 신경정신의학 1978, 제 17권 제 4호 2 343-351 (9 pages)
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고령환자에 대한 정신약물 사용
대한신경정신의학회 신경정신의학 1979, 제 18권 제 4호 13 459-465 (7 pages)
