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대사증후군에 대한 모발미네랄함량과 심박변이도의 연관성 연구
김현진(Hyun Jin Kim), 이재은(Jae Eun Ie), 허수정(Su Jeong Heo), 조현주(Hyun Ju Cho), 명성민(Sung Min Myoung) 한방비만학회 대한한방비만학회지 13 Pages
한방비만학회 대한한방비만학회지 2009, 제 9권 제 2호 4 33-45 (13 pages)
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오약순기산 발효물의 급성 독성에 관한 연구
이지혜(Ji Hye Lee), 곽동훈(Dong Hoon Kwak), 김태수(Tae Soo Kim), 마진열(Jin Yeul Ma) 한방비만학회 대한한방비만학회지 8 Pages
한방비만학회 대한한방비만학회지 2011, 제 11권 제 2호 3 25-32 (8 pages)
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C2C12 근아세포에서 산자나무 유래 Isorhamnetin의 산화적스트레스에 의한 Apoptosis 유발 억제 효과
최영현(Yung Hyun Choi) 한방비만학회 대한한방비만학회지 11 Pages
한방비만학회 대한한방비만학회지 2015, 제 15권 제 2호 4 93-103 (11 pages)
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삼정환의 랫드를 이용한 단회 경구투여 독성시험
김민지(Min jee Kim), 이명종(Myeong jong Lee), 김호준(Ho jun Kim) 한방비만학회 대한한방비만학회지 5 Pages
한방비만학회 대한한방비만학회지 2017, 제 17권 제 2호 5 96-100 (5 pages)
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Antioxidant Effects of Pyrogallol in Neural Cells and Mice Brain
Jisub Moon, Heesun Gwak, Tae-Hee Lee, Eun Suk An, Yun-Bae Kim, Dongsun Park 한국교원대학교 뇌기반교육연구소 Brain, Digital, & Learning 12 Pages
한국교원대학교 뇌기반교육연구소 Brain, Digital, & Learning 2019, 제 9권 제 3호 2 113-124 (12 pages)
the mRNA expression of superoxide dismutases 1, 2, and 3, glutathione peroxidase (GPx)1, and phospholipid hydroperoxide GPx in N2A and F3 cells, in the brains of mice that were orally administered pyrogallol (1.0, 3.2, and 10.0 mg/kg/day) for 7 days. The mice did not exhibit any toxic effects due to this treatment. Taken together, although pyrogallol induced cell death at high concentrations, it might be a good candidate antioxidant for neurodegenerative disease at low concentrations. -
The change of signaling pathway on the electrical stimulated contraction in streptozotocin-induced bladder dysfunction of rats
Jong Soo Han, Young Sil Min, Gil Hyung Kim, Sang-hyun Chae, Yoonjin Nam, Jaehwi Lee, Seok-Yong Lee, Uy Dong Sohn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.5 11 577-584 (8 pages)
Bladder dysfunction is a common complication of diabetes mellitus (DM). However, there have been a few studies evaluating bladder smooth muscle contraction in DM in the presence of pharmacological inhibitors. In the present study, we compared the contractility of bladder smooth muscle from normal rats and DM rats. Furthermore, we utilized pharmacological inhibitors to delineate the mechanisms underlying bladder muscle differences between normal and DM rats. DM was established in 14 days after... -
Carbon monoxide releasing molecule-2 protects mice against acute kidney injury through inhibition of ER stress
Md Jamal Uddin, Eun Seon Pak, Hunjoo Ha 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.5 10 567-575 (9 pages)
to determine the protective effect of carbon monoxide releasing molecule-2 (CORM2) on AKI associated with ER stress. Kidney injury was induced after LPS (15 mg/kg) treatment at 12 to 24 h in C57BL/6J mice. Pretreatment of CORM2 (30 mg/kg) effectively prevented LPS-induced oxidative stress and inflammation during AKI in mice. CORM2 treatment also effectively inhibited LPS-induced ER stress in AKI mice. In order to confirm effect of CO on the pathophysiological role of tubular epithelial cells in... -
Inhibitory effects of 2,6-di-tert-butyl-4-hydroxymethylphenol on asthmatic responses to ovalbumin challenge in conscious guinea pigs
Seul-YongJeong, Ji-YunLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.1 9 81-89 (9 pages)
This study evaluated the anti-asthmatic activities of 2,6-di-tert-butyl-4-hydroxymethylphenol (DBHP) that is a potent phenolic antioxidant in edible vegetable oil. The effects of DBHP on bronchial asthma were evaluated by determining the specific airway resistance (sRaw) and tidal volume (TV) during the immediate asthmatic response (IAR) and the late-phase asthmatic response (LAR) in guinea pigs with aerosolized ovalbumin-induced asthma. Recruitment of leukocytes and the levels of biochemical... -
Alleviation of ascorbic acid-induced gastric high acidity by calcium ascorbate in vitro and in vivo
Joon-KyungLee, Sang-HyukJung, Sang-EunLee, Joo-HuiHan, EunjiJo, Hyun-SooPark, Kyung-SunHeo, DeasunKim, Jeong-SookPark, Chang-SeonMyung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.1 4 35-42 (8 pages)
Ascorbic acid is one of the most well-known nutritional supplement and antioxidant found in fruits and vegetables. Calcium ascorbate has been developed to mitigate the gastric irritation caused by the acidity of ascorbic acid. The aim of this study was to compare calcium ascorbate and ascorbic acid, focusing on their antioxidant activity and effects on gastric juice pH, total acid output, and pepsin secretion in an in vivo rat model, as well as pharmacokinetic parameters. Calcium ascorbate and... -
Morroniside on anti-inflammation activities in rats following acute myocardial infarction
BangxingYu, GuoxingZhang, YiAn, WenWang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.1 2 17-21 (5 pages)
Our previous studies have confirmed that morroniside has neuroprotective effects. However, the effects of morroniside on cardiac myocardium remain unknown. Rats were anaesthetized with 10% chloral hydrate (0.35~0.4 mL/kg) and an acute myocardial infarction (AMI) was induced by ligating the anterior descending coronary artery (LAD). Following AMI, morroniside was administered intragastrically for 3 consecutive days at doses of 45, 90 and 180 mg/kg, respectively. Lactate dehydrogenase (LDH) and...
