학지사 뉴논문

총 490건 검색

본문검색 결과만 보기

정확도순

최신순

등재순

발행기간

전체
최근 1년
최근 3년
직접입력

적용하기

본문검색

포함

제외

10개씩

281.

Spinal Metabotropic Glutamate Receptors (mGluRs) are Involved in the Melittin-induced Nociception in Rats

ChulHyunCho, HongKeeShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.5 4 237-244 (8 pages)

ChulHyunCho, HongKeeShin 저
...
- 3,000원
Intraplantar injection of melittin has been known to induce sustained decrease of mechanical threshold and increase of spontaneous flinchings. The present study was undertaken to investigate how the melittin-induced nociceptive responses were modulated by changes of metabotropic glutamate receptor (mGluR) activity. Changes in paw withdrawal threshold (PWT), number of flinchings and paw thickness were measured at a given time point after injection of melittin (10Ռg/paw) into the mid-plantar...
282.

Effects of Apigenin on Glutamate-induced [Ca2+]i Increases in Cultured Rat Hippocampal Neurons

Ji-HwaHan, KiJungKim, Hyun-JongJang, JuHoJang, Myung-JunKim, KiWugSung, Duck-JooRhie, Yang-HyeokJo, SangJuneHahn, Mun-YongLee, ShinHeeYoon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.2 2 43-50 (8 pages)

Ji-HwaHan, KiJungKim, Hyun-JongJang, JuHoJang, Myung-JunKim, KiWugSung, Duck-JooRhie, Yang-HyeokJo, SangJuneHahn, Mun-YongLee, ShinHeeYoon 저
...
- 3,000원
Flavonoids have been shown to affect calcium signaling in neurons. However, there are no reports on the effect of apigenin on glutamate-induced calcium signaling in neurons. We investigated whether apigenin affects glutamate-induced increase of free intracellular Ca2+ concentration ([Ca2+]i) in cultured rat hippocampal neurons, using fura-2-based digital calcium imaging and microfluorimetry. The hippocampal neurons were used between 10 and 13 days in culture from embryonic day 18 rats....
283.

Effects of TGF-β;1 Ribbon Antisense on CCl4-induced Liver Fibrosis

Kyung-OhDoh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.1 1 1-6 (6 pages)

Kyung-OhDoh 저
...
- 3,000원
Ribbon-type antisense oligonucleotide to TGF-Ղ1 (TGF-Ղ1 RiAS) was designed and tested to prevent or resolve the fibrotic changes induced by CCl4 injection. When Hepa1c1c7 cells were transfected with TGF-Ղ1 RiAS, the level of TGF-Ղ1 mRNA was effectively reduced. TGF-Ղ1 RiAS, mismatched RiAS, and normal saline were each injected...
284.

Developmental Disability Animal Model Based on Neonatal Lipopolysaccharide with Altered 5-HT Function

JaeGooKim, MinSooKim, SeoulLee, GunTaeKim, JongDooLee, DongGooKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.3 6 113-119 (7 pages)

JaeGooKim, MinSooKim, SeoulLee, GunTaeKim, JongDooLee, DongGooKim 저
...
- 3,000원
Developmental disability shows life-long behavioral abnormality with no significant physical malformation. This study was undertaken to develop an animal model for developmental disability by using two-factor approach. Lipopolysaccharide (LPS), a bacterial toxin, and NAN-190, a 5-HT1A receptor antagonist, were administered to Sprague-Dawley rats on postnatal day (PND) 5 to induce inflammation and an altered 5-HT system, respectively. Long-term alteration of behavior occurred in the drug-treated...
285.

Effects of (-)-Epigallocatechin-3-gallate on Brain Infarction and the Activity Change of Matrix Metalloproteinase-9 Induced by Middle Cerebral Artery Occlusion in Mice

YongRiQian, JiHyunKook, ShinaeHwang, DoKyungKim, Jong-KeunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.3 2 85-88 (4 pages)

YongRiQian, JiHyunKook, ShinaeHwang, DoKyungKim, Jong-KeunKim 저
...
- 1,500원
Matrix metalloproteinases (MMPs) can degrade a wide range of extracellular matrix components. It has been reported that MMP-9 are activated after focal ischemia in experimental animals. (⁣)-Epigallocatechin-3-gallate (EGCG), a major constituent of green tea polyphenols, is a potent free radical scavenger and reduces the neuronal damage caused by oxygen free radicals. And it has been known that EGCG could reduce the infarction volume in focal brain ischemia and inhibit MMP-9 activity. To...
286.

Development of Luciferase Reporter Gene-based Cell Bioassay for the Aromatic Hydrocarbon Receptor Agonists

Sun-YoungKim, Eun-JungChoi, Jae-HoYang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.6 9 349-354 (6 pages)

Sun-YoungKim, Eun-JungChoi, Jae-HoYang 저
...
- 3,000원
The aromatic hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates many of the biological and toxicological effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, dioxin) and related chemicals. The application of recombinant reporter plasmid such as the firefly luciferase gene has proven to be a very effective method to detect these chemicals. The bioassay system, CALUX, is sensitive in directly detecting AhR-agonists from a variety of environmental and biologic...
287.

Effect of Rosiglitazone on Myocardial Ischemia-Reperfusion Injury in Rat Heart

Ki-ChanHa 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.4 3 181-186 (6 pages)

Ki-ChanHa 저
...
- 3,000원
This study was undertaken to evaluate whether peroxisome proliferator-activated-receptor-gamma (PPAR-γ) agonist-rosiglitazone (ROSI) induces postischemic functional recovery in Langendorf heart model. Hearts isolated from normal rats were subjected to 20 min of normoxia or 25 min zero-flow ischemia followed by 50 min reperfusion. In this acute protocol, ROSI (20μg/ml) administered 10 min before ischemia had no effect on hemodynamic cardiac function, but had protective effect on lipid...
288.

5-Hydroxytryptamine Inhibits Glutamatergic Synaptic Transmission in Rat Corticostriatal Brain Slice

HyeongSeokCho, SeJoonChoi, Ki-JungKim, HyunHoLee, SeongYunKim, YoungJinCho, Ki-WugSung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.5 1 255-262 (8 pages)

HyeongSeokCho, SeJoonChoi, Ki-JungKim, HyunHoLee, SeongYunKim, YoungJinCho, Ki-WugSung 저
...
- 3,000원
Striatum is involved in the control of movement and habitual memory. It receives glutamatergic input from wide area of the cerebral cortex as well as an extensive serotonergic (5-hydroxytryptamine, 5-HT) input from the raphe nuclei. In our study, the effects of 5-HT on synaptic transmission were studied in the rat corticostriatal brain slice using in vitro whole-cell recording technique. 5-HT inhibited the amplitude as well as frequency of spontaneous excitatory postsynaptic currents (sEPSC)...
289.

Effects ofSphingosine-1-phosphate, Furosemide and Indomethacin on Mucin Release from Airway Goblet Cells

Ju-OckKim, HyungSooKim, Sun-YoungKim, Seong-SooJeong, HoJinHeo, JeongHoSeok, ChoongJaeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.3 4 155-158 (4 pages)

Ju-OckKim, HyungSooKim, Sun-YoungKim, Seong-SooJeong, HoJinHeo, JeongHoSeok, ChoongJaeLee 저
...
- 1,500원
In this study, we investigated whether sphingosine-1-phosphate, furosemide, and indomethacin affect mucin release from airway goblet cells. Confluent primary hamster tracheal surface epithelial cells were metabolically radiolabeled and chased for 30 min or 24 hr in the presence of varying concentrations of the above agents to assess the effects on 3H-mucin release. Sphingosine-1-phosphate stimulated mucin release during 30 min of treatment period in a dose-dependent manner. However, furosemide...
290.

D-Amphetamine Causes Dual Actions on Catecholamine Release from the Rat Adrenal Medulla

Geon-HanLim, Gwang-MoonNa, Seon-YoungMin, Yoo-SeokSeo, Chan-WonPark, Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.1 7 45-54 (10 pages)

Geon-HanLim, Gwang-MoonNa, Seon-YoungMin, Yoo-SeokSeo, Chan-WonPark, Dong-YoonLim 저
...
- 3,000원
The present study was designed to examine the effect of d-amphetamine on CA release from the isolated perfused model of the rat adrenal gland, and to establish its mechanism of action. D- amphetamine (10∼100μM), when perfused into an adrenal vein of the rat adrenal gland for 60 min, enhanced the CA secretory responses evoked by ACh (5.32⁓10⁣3 M), excess K⁢ (5.6⁓10⁣2 M, a membrane depolarizer), DMPP (10⁣4 M, a selective neuronal nicotinic Nn-receptor agonist)...

한주간 이슈검색어