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시스플라틴에 의해 유발된 식욕부진이 쥐의 뒷다리근에 미치는 영향
김진일, 최명애 한국기초간호학회 Journal of Korean Biological Nursing Science 8 Pages
한국기초간호학회 Journal of Korean Biological Nursing Science 2012, Vol.14 No.1 7 49-56 (8 pages)
시스플라틴(cis-Diammineplatinum(II) dichloride, CDDP)은 백금화합물로 탁월한 항암효과를 가지고 있어 고형암의 치료에 가장 많이 사용되는 항암제 중 하나이다(Decatris, Sundar, & O’Byrne, 2004). 특히 두경부, 폐, 고환, 난소, 유방 및 폐 등의 고형암 치료에 중요한 역할을 차지하고 있다(Hanigan, & Devarajan, 2003). 그러나 이러한 중요성에 반해 시스플라틴이 가지고 있는 부작용으로 인해 치료효과가 제한적인 것으로 알려져 있다(Decatris et al., 2004). 일반적으로 임상에서 이용되는 항암치료는 고용량 항암제를 투여... -
혈관신생억제를 통한 종양치료의 한의학적 고찰
송기철, 최병렬, 이용연, 서상훈, 유화승, 조정효, 이연월, 손창규, 조종관, 최우진, Song. Kee-Cheol, Choi. Byung-Ryel, Lee. Yong-Yeon, Seo. Sang-Hoon, Yoo. Hwa-Seung, Cho. Jung- 대한한방내과학회 대한한방내과학회지 7 Pages
대한한방내과학회 대한한방내과학회지 2001, Vol.22 No.4 639-645 (7 pages)
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Zerumbone, Sesquiterpene Photochemical from Ginger, Inhibits Angiogenesis
Ju-HyungPark, GeunMookPark, Jin-KyungKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.4 5 335-340 (6 pages)
Here, we investigated the role of zerumbone, a natural cyclic sesquiterpene of Zingiber zerumbet Smith, on angiogenesis using human umbilical vein endothelial cells (HUVECs). Zerumbone inhibited HUVECs proliferation, migration and tubule formation, as well as angiogenic activity by rat aorta explants. In particular, zerumbone inhibited phosphorylation of vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1, which are key regulators of endothelial cell function... -
The effect of physical training on glutamate transporter expression in an experimental ischemic stroke rat model
Gye-Yeop Kim, Eun-Jung Kim 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2013, 제 2권 제 2호 5 87-91 (5 pages)
Objective: The present study was aimed at determining the effect of physical training on glutamate transporter activity in a middle cerebral artery occlusion (MCAO)-induced ischemia injury rat model. Design: Randomized controlled trial. Methods: In this study, we randomly divided them into three groups. Group I included non-occlusion sham controls (n=10), Group II included non-physical training after MCAO (n=10), and Group III included rats that were subjected to physical training after MCAO... -
Platelet rich plasma improves dermal therapeutic effect of mesenchymal stem cells via enhancing angiogenesis
Hyun-wook Myung, Se-hwan Shim, Hyo-sun Jang, Jae Kyung Myung, Won Suk Jang, Sun Joo Lee, Hye-won Kim, Janet Lee, Ji Hoon Kang, Ju Hui Par 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 192 315-316 (2 pages)
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Clinical assessment after human adipose stem cell transplantation into dogs
Seok Hee Lee, Erif M.N. Setyawan, Yoo Bin Choi, Jeong Chan Ra, Sung Keun Kang, Byeong Chun Lee, Geon A Kim 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 3호 15 452-461 (10 pages)
by human ASC therapy. Therefore, in the present study, a clinical assessment after human ASC transplantation into dogs was undertaken. A total of 12 healthy male dogs were selected and divided into four groups: saline infusion, saline bolus, ASC infusion, and ASC bolus groups. Physical assessment and blood analysis were performed following ASC transplantation, and the concentrations of angiogenic factors, and pro- and anti-inflammatory cytokines were measured by enzyme-linked immunosorbent assay... -
Paracrine influence of human perivascular cells on the proliferation of adenocarcinoma alveolar epithelial cells
EunbiKim, SunghunNa, BorimAn, Se-RanYang, WooJinKim, Kwon-SooHa, Eun-TaekHan, WonSunPark, Chang-MinLee, JiYoonLee, Seung-JoonLee, Seok-HoHo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.2 3 161-168 (8 pages)
Understanding the crosstalk mechanisms between perivascular cells (PVCs) and cancer cells might be beneficial in preventing cancer development and metastasis. In this study, we investigated the paracrine influence of PVCs derived from human umbilical cords on the proliferation of lung adenocarcinoma epithelial cells (A549) and erythroleukemia cells (TF-1α and K562) in vitro using TranswellⓇ co-culture systems. PVCs promoted the proliferation of A549 cells without inducing morphological... -
Increasing injection frequency enhances the survival of injected bone marrow derived mesenchymal stem cells in a critical limb ischemia animal model
WoongCholKang, PyungChunOh, KyounghoonLee, TaehoonAhn, KyungheeByun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.6 12 657-667 (11 pages)
Critical limb ischemia (CLI) is one of the most severe forms of peripheral artery diseases, but current treatment strategies do not guarantee complete recovery of vascular blood flow or reduce the risk of mortality. Recently, human bone marrow derived mesenchymal stem cells (MSCs) have been reported to have a paracrine influence on angiogenesis in several ischemic diseases. However, little evidence is available regarding optimal cell doses and injection frequencies. Thus, the authors undertook... -
Regulation of retinal angiogenesis by endothelial nitric oxide synthase signaling pathway
JungMinHa, SeoYeonJin, HyeSunLee, HwaKyoungShin, DongHyungLee, SangHeonSong, ChiDaeKim, SunSikBae 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.5 11 533-538 (6 pages)
Angiogenesis plays an essential role in embryo development, tissue repair, inflammatory diseases, and tumor growth. In the present study, we showed that endothelial nitric oxide synthase (eNOS) regulates retinal angiogenesis. Mice that lack eNOS showed growth retardation, and retinal vessel development was significantly delayed. In addition, the number of tip cells and filopodia length were significantly reduced in mice lacking eNOS. Retinal endothelial cell proliferation was significantly... -
Preventive Effect of Polysaccharide of Larimichthys crocea Swim Bladder on Reserpine Induced Gastric Ulcer in ICR Mice
Gui-JieLi, PengSun, RuiWang, Ya-LinZhou, YuQian, XinZhao 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.2 14 183-190 (8 pages)
This project’s aim was to determine the reserpine-induced gastric ulcer preventive effect of poly-saccharide of Larimichthys crocea swim bladder (PLCSB) in ICR mice. The anti-gastric ulcer effects of polysaccharide of Larimichthys crocea swim bladder was evaluated in mice model using mor-phological test, serum levels assay, cytokine levels assay, tissue contents analysis, reverse transcrip-tion-polymerase chain reaction (RT-PCR) analysis and western bolt assay. High concentration (50 mg/kg...


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