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21.

Activation of Akt/protein kinase B mediates the protective effects of mechanical stretching against myocardial ischemia-reperfusion injury

Chan-Hyung Kim*, Jia Hao, Hee-Yul Ahn, Si Wook Kim* 대한수의학회 Journal of Veterinary Science 10 Pages

대한수의학회 Journal of Veterinary Science 2012, 제 13권 제 3호 4 235-244 (10 pages)

Chan-Hyung Kim*, Jia Hao, Hee-Yul Ahn, Si Wook Kim* 저
...
- 3,000원
stretch-activated ion channels (SACs), inhibited the stretch-induced phosphorylation of Akt and GSK-3b. Furthermore, SIC was abrogated by wortmannin and Gd. In vivo stretching induced by an aorto-caval shunt increased Akt phosphorylation and reduced myocardial infarction; these effects were diminished by wortmannin and Gd pretreatment. Our results showed that mechanical stretching can provide cardioprotection against ischemia- reperfusion injury. Additionally, the activation of Akt, which might ...
22.

The Critical Roles of Zinc: Beyond Impact on Myocardial Signaling

SungRyulLee, SuJinNoh, JuliusRyanPronto, YuJeongJeong, HyoungKyuKim, InSungSong, ZhelongXu, HyogYoungKwon, SeChanKang, Eun-HwaSohn, KyungS 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.5 1 389-400 (12 pages)

SungRyulLee, SuJinNoh, JuliusRyanPronto, YuJeongJeong, HyoungKyuKim, InSungSong, ZhelongXu, HyogYoungKwon, SeChanKang, Eun-HwaSohn, KyungS 저
...
- 4,100원
Zinc has been considered as a vital constituent of proteins, including enzymes. Mobile reactive zinc (Zn2+) is the key form of zinc involved in signal transductions, which are mainly driven by its binding to proteins or the release of zinc from proteins, possibly via a redox switch. There has been growing evidence of zinc’s critical role in cell signaling, due to its flexible coordination geometry and rapid shifts in protein conformation to perform biological reactions. The importance and...
23.

The Effects of Ischemic Postconditioning on Myocardial Function and Nitric Oxide Metabolites Following Ischemia-Reperfusion in Hyperthyroid Rats

JalalZaman, SajjadJeddi, AsgharGhasemi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.6 6 481-488 (8 pages)

JalalZaman, SajjadJeddi, AsgharGhasemi 저
...
- 3,000원
myocardial IR injury in hyperthyroid male rats. Hyperthyroidism was induced with administration of thyroxine in drinking water (12 mg/L) over a period of 21 days. After thoracotomy, the hearts of control and hyperthyroid rats were perfused in the Langendorff apparatus and subjected to 30 minutes global ischemia, followed by 120 minutes reperfusion; IPost, intermittent early reperfusion, was induced instantly following ischemia. In control rats, IPost significantly improved the left ventricular...
24.

Korean Red Ginseng Induced Cardioprotection against Myocardial Ischemia in Guinea Pig

KyuHeeLim, Chang-WonKang, Jin-YongChoi, Jong-HoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.4 5 283-289 (7 pages)

KyuHeeLim, Chang-WonKang, Jin-YongChoi, Jong-HoonKim 저
...
- 3,000원
This study was designed to evaluate the protective effect of Korean red ginseng (KRG) against ischemia/reperfusion (I/R) injury in isolated guinea pig heart. KRG has been shown to possess various ginsenosides, which are the major components of Panax ginseng. These components are known naturally occurring compounds with beneficial effects and free radical scavenging activity. The heart was induced to ischemia for 60 min, followed by 120 min reperfusion. The hearts were randomly allocated into...
25.

Mechanical Stretch-Induced Protection against Myocardial Ischemia- Reperfusion Injury Involves AMP-Activated Protein Kinase

JiaHao, Hun-SikKim, WoongChoi, TaeSunHa, Hee-YulAhn, Chan-HyungKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.1 1 1-9 (9 pages)

JiaHao, Hun-SikKim, WoongChoi, TaeSunHa, Hee-YulAhn, Chan-HyungKim 저
...
- 3,000원
investigated if the activation of AMPK is involved in stretch-induced cardioprotection (SIC). Intraventricular balloon and aorto-caval shunt (ACS) were used to stretch rat hearts ex vivo and in vivo, respectively. Stretch preconditioning reduced myocardial infarct induced by ischemia-reperfusion (I/R) and improved post-ischemic functional recovery. Phosphorylation of AMPK and its downstream substrate, acetyl-CoA carboxylase (ACC) were increased by mechanical stretch and ACC phosphorylation was...
26.

Effect of Rosiglitazone on Myocardial Ischemia-Reperfusion Injury in Rat Heart

Ki-ChanHa 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.4 3 181-186 (6 pages)

Ki-ChanHa 저
...
- 3,000원
This study was undertaken to evaluate whether peroxisome proliferator-activated-receptor-gamma (PPAR-γ) agonist-rosiglitazone (ROSI) induces postischemic functional recovery in Langendorf heart model. Hearts isolated from normal rats were subjected to 20 min of normoxia or 25 min zero-flow ischemia followed by 50 min reperfusion. In this acute protocol, ROSI (20μg/ml) administered 10 min before ischemia had no effect on hemodynamic cardiac function, but had protective effect on lipid...
27.

Myocardial Protection by Recombinant Soluble P-selectin Glycoprotein Ligand-1 Suppression of Neutrophil and Platelet Interaction Following Ischemia and Reperfusion

SangSooHam, YoonYoungJang, JinHoSong, HyangMiLee, KwangJoonKim, JunSikHong, YongKyooShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.6 10 507-513 (7 pages)

SangSooHam, YoonYoungJang, JinHoSong, HyangMiLee, KwangJoonKim, JunSikHong, YongKyooShin 저
...
- 3,000원
role in myocardial ischemia/reperfusion (MI/R) injury. Moreover, platelets are also important blood cells that can aggravate myocardial ischemic injury. This study was designed to test the effects of PMNs and platelets separately and together in provoking cardiac dysfunction in isolated perfused rat hearts following ischemia and reperfusion. Additional control rat hearts were perfused with 75⁓106 PMNs, with 75⁓106 platelets, or with 75⁓106 PMNs⁢75⁓106 platelets over...
28.

Down-regulation of TNF-$alpha$ and IL-6 by Higenamine is Responsible for Reduction of Infarct Size and Myocardial Ischemic Injury in the Rat

Lee. Young-Soo, Kang. Young-Jin, Lee. Bog-Kyu, Ko. Young-Shim, Park. Min-Kyu, Seo. Han-Geuk, Yun-Choi. Hye-Sook, Chang. Ki-Churl 한국응용약물학회 The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmaco 9 Pages

한국응용약물학회 The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmaco 2001, Vol.9 No.3 167-175 (9 pages)

Lee. Young-Soo, Kang. Young-Jin, Lee. Bog-Kyu, Ko. Young-Shim, Park. Min-Kyu, Seo. Han-Geuk, Yun-Choi. Hye-Sook, Chang. Ki-Churl 저

이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
- 무료
29.

Butyrate and Propionate, Short Chain Fatty Acids, Attenuate Myocardial Damages by Inhibition of Apoptosis in a Rat Model of Ischemia-reperfusion

Lim. Sun-Ha, Song. Kyung-Sik, Lee. Jong-Won 한국응용생명화학회 Journal of the Korean Society for Applied Biological Chemistry 8 Pages

한국응용생명화학회 Journal of the Korean Society for Applied Biological Chemistry 2010, Vol.53 No.5 570-577 (8 pages)

Lim. Sun-Ha, Song. Kyung-Sik, Lee. Jong-Won 저

이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
- 무료
30.

Butyrate and Propionate, Short Chain Fatty Acids, Attenuate Myocardial Damages by Inhibition of Apoptosis in a Rat Model of Ischemia-reperfusion

Lim. Sun-Ha, Song. Kyung-Sik, Lee. Jong-Won 한국응용생명화학회 Journal of applied biological chemistry 8 Pages

한국응용생명화학회 Journal of applied biological chemistry 2010, Vol.53 No.5 570-577 (8 pages)

Lim. Sun-Ha, Song. Kyung-Sik, Lee. Jong-Won 저

이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
- 무료

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