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전체 선택해제
총 131건 검색
본문검색 결과만 보기
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Antiproliferative and Cytotoxic Effects of Resveratrol in Mitochondria- Mediated Apoptosis in Rat B103 Neuroblastoma Cells
Md.AtaurRahman, Nam-HoKim, Seung-HyukKim, Sung-MinOh, Sung-OhHuh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.5 5 321-326 (6 pages)
Resveratrol, a natural compound, has been shown to possess anti-cancer, anti-aging, anti-inflammatory, anti-microbial, and neuroprotective activities. In this study, we examined the antiproliferative and cytotoxicity properties of resveratrol in Rat B103 neuroblastoma cells; although it's molecular mechanisms for the biological effects are not fully defined. Here, we examined the cellular cytotoxicity of resveratrol by cell viability assay, antiproliferation by BrdU assay, DNA fragmentation by... -
The Protective Effect of Black Ginseng Against Transient Focal Ischemia-induced Neuronal Damage in Rats
Hyun-JungPark, HyunSooShim, KyungSooKim, InsopShim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.6 3 333-338 (6 pages)
Black ginseng (BG) has been widely used as herbal treatment for improving physiological function. In order to investigate the neuroprotective action of this herbal medicine, we examined the influence of BG on the learning and memory of rats using the Morris water maze, and we studied the effects of BG on the central cholinergic system and neural nitric oxide synthesis in the hippocampus of rats with neuronal and cognitive impairment. After middle cerebral artery occlusion was applied for 2h, the... -
The Protective Effect of Epigallocatechin-3 Gallate on Ischemia/ Reperfusion Injury in Isolated Rat Hearts: An ex vivo Approach
ChengShiPiao, Do-SungKim, Ki-ChanHa, Hyung-RyongKim, Han-JungChae, Soo-WanChae 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.5 2 259-266 (8 pages)
The aim of this study was to evaluate the preventive role of epigallocatechin-3 gallate (EGCG, a derivative of green tea) in ischemia/reperfusion (I/R) injury of isolated rat hearts. It has been suggested that EGCG has beneficial health effects, including prevention of cancer and heart disease, and it is also a potent antioxidant. Rat hearts were subjected to 20 min of normoxia, 20 min of zero-flow ischemia and then 50 min of reperfusion. EGCG was perfused 10 min before ischemia and during the... -
Indomethacin Induces Apoptosis in NCI-H1299 Human Lung Carcinoma Cells
BumShikKim, SoonAeKim, MiJaKim, HeeJaeLee, Seung-JoonPark, Jee-ChangJung, Chang-JuKim, Sung-VinYim, Joo-HoChung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.2 8 177-181 (5 pages)
Recently, nonsteroidal anti-inflammatory drugs (NSAIDs) have been found to be useful in the chemoprevention of colon cancer. To investigate whether indomethacin, an NSAIDs, induces apoptosis and thus assess the possibility of its application in the chemoprevention of human lung cancer, we have performed MTT assay, TUNEL assay, DAPI staining, and flow cytometric analysis using human lung carcinoma cell line NCI-H1299. Through morphological and biochemical analyses, it was demonstrated that... -
Vitamin A 유도체로 인한 간의 약물대사효소 변동
이향우(H.W. Lee), 유경자(K.Z. Ryu), 노재열(J.Y. Ro), 홍사석(S.S. Hong) 대한약리학회 대한약리학잡지 8 Pages
대한약리학회 대한약리학잡지 1982, 제 18권 제 1호 8 65-72 (8 pages)
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황기의 유방암 발생 억제효과
소명숙, 김아린 한국보건기초의학회 한국보건기초의학회지 6 Pages
한국보건기초의학회 한국보건기초의학회지 2013, Vol.6 No.3 9 172-177 (6 pages)
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남원자생 허브의 혼합추출물이 창상치유에 미치는 영향
박승택, 김정우, 정석희, 서영미 한국기초간호학회 Journal of Korean Biological Nursing Science 7 Pages
한국기초간호학회 Journal of Korean Biological Nursing Science 2012, Vol.14 No.2 6 122-128 (7 pages)
창상의 회복효과를 높이기 위해 보다 나은 치료물질 또는 치료방법을 찾고자 연구자들의 계속된 노력이 이루어지고 있다(Kwon, Choi, Yoon, & Ki, 2010; Nam, 2010; Zhao, 2009). 이렇게 관심을 가지는 치료물질 중에 허브가 있으며, 이것들을 치료제로 개발하고자 효능 분석과 효과에 대한 연구가 진행되고 있다(Battaglia, 2003; Kwon et al., 2010; Nam, 2010). 최근 간호학에서도 허브에서 추출한 에센셜 오일(essential oil)을 창상치유 간호에 적용하는 것에 관심을 보이고 있다(Hur & Han, 2004). 이러한 허브는 서양에서... -
흰쥐의 율무식이가 에스트로겐 생성에 미치는 영향
한국웰니스학회 한국웰니스학회지 2014, 제 9권 1호 19 215-224 (10 pages)
본 연구는 암컷 흰쥐를 실험대상으로 율무식이를 4주간 섭취시켜 체중변화와 estrogen의 생성에 미치는 영향을 알아보았다. 식 이조건은 기본식이군(A), 분말 율무를 증류수에 희석하여 강제투여방식으로 매일 2g투여군(B), 4g투여군(C), 6g투여군(D), 6g과 조 제된 율무 고형식이 투여군(E), 3일 간격으로 6g율무식이 투여군(F), 5일 간격으로 6g율무식이 투여군(G) 등 총 7군에서 율무식이 섭취량에 따른 변화를 관찰하여 다음과 같은 결과를 얻었다. 율무식이는 섭취량이 많을 수 록 체중증가가 억제되었으며, 에스트로 겐의 생성은... -
The Inhibitory Effect of Chlorophyllin is Influenced by Different Promotion Stages in DMBA-TPA-induced Mouse Skin Carcinogenesis
Kim. Jin, Yook. Jong-In, Park. Kwang-Kyun, Lee. Eun-Ha, Jung. So-Young, Joon. Yin-Liu, Kyung. Chul-Hong, Kim. Ju, Chung. Won-Yoon 한국환경성돌연변이발암원학회 Environmental mutagens and carcinogens 10 Pages
한국환경성돌연변이발암원학회 Environmental mutagens and carcinogens 1999, Vol.19 No.1 46-55 (10 pages)
