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Cyclosporine A에 의해 과증식된 조직의 치은섬유아세포에서 MMP-1, TIMP-1, TGF-β1, FGF-2, 그리고 FGF-7의 mRNA 발현에 관한 연구
마평수, 이재선, 박창주, 황경균, 심광섭 대한치과이식임플란트학회 Journal of Dental Implant Research 13 Pages
대한치과이식임플란트학회 Journal of Dental Implant Research 2008, 제 27권 1호 1 1-13 (13 pages)
Cyclosporine A(CsA)는 광범위하게 사용되는 면역 억제제로, 장기이식환자의 거부반응을 막기 위해 사 용되고, 자가 면역질환의 치료에도 사용되고 있다1-3). CsA 투여와 관련된 부작용은 신독성, 간독성, 고혈압, 신경독성, 치은증식이 보고 되었다. -
분리 대두단백질 섭취와 염분 제한이 Streptozotocin으로 유도된 당뇨 횐쥐의 혈청 지질 수준 및 신장기능에 미치는 영향
정수현, 박양자 동아시아식생활학회 東아시아食生活學會誌 11 Pages
동아시아식생활학회 東아시아食生活學會誌 2001, Vol.11 No.5 368-378 (11 pages)
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Downregulation of cellular prion protein inhibited the proliferation and invasion and induced apoptosis of Marek’s disease virus-transformed avian T cells
Xuerui Wan, Runxia Yang, Guilin Liu, Manling Zhu, Tianliang Zhang, Lei Liu, Run Wu* 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 2호 6 171-178 (8 pages)
Cellular prion protein (PrP) is ubiquitously expressed in the cytomembrane of a considerable number of eukaryotic cells. Although several studies have investigated the functions of PrP in cell proliferation, cell apoptosis, and tumorigenesis of mammals, the correlated functions of chicken PrP (chPrP) remain unknown. In this study, stable chPrP-downregulated Marek’s disease (MD) virus-transformed avian T cells (MSB1-SiRNA-3) were established by introducing short interfering RNA (SiRNA) targeting... -
Balantidiasis in the gastric lymph nodes of Barbary sheep (Ammotragus lervia): an incidental finding
Ho-Seong Cho, Sung-Shik Shin, Nam-Yong Park 대한수의학회 Journal of Veterinary Science 3 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 2호 20 207-209 (3 pages)
A 4-year-old female Barbary sheep (Ammotragus lervia) was found dead in the Gwangju Uchi Park Zoo. The animal had previously exhibited weakness and lethargy, but no signs of diarrhea. The carcass was emaciated upon presentation. The main gross lesion was characterized by severe serous atrophy of the fat tissues of the coronary and left ventricular grooves, resulting in the transformation of the fat to a gelatinous material. The rumen was fully distended with food, while the abomasum evidenced... -
EGCG Blocked Phenylephrin-Induced Hypertrophy in H9C2 Cardiomyocytes, by Activating AMPK-Dependent Pathway
YiCai, LiZhao, YuanQin, Xiao-QianWu 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.3 3 203-210 (8 pages)
AMP-activated protein kinase (AMPK) is a key regulator of energy metabolism. Previous studies have shown that activation of AMPK results in suppression of cardiac myocyte hypertrophy via inhibition of the p70S6 kinase (p70S6K) and eukaryotic elongation factor-2 (eEF2) signaling pathways. Epigallocatechin-3-gallate (EGCG), the major polyphenol found in green tea, possesses multiple protective effects on the cardiovascular system including cardiac hypertrophy. However, the molecular mechanisms has... -
A Novel Pathway Underlying the Inhibitory Effects of Melatonin on Isolated Rat Urinary Bladder Contraction
JuneHyunHan, InHoChang, SoonChulMyung, MooYeolLee, WonYongKim, SeoYeonLee, ShinYoungLee6, SeungWookLee, KyungDoKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.1 6 37-42 (6 pages)
The aim of the present study was to elucidate the direct effects of melatonin on bladder activity and to determine the mechanisms responsible for the detrusor activity of melatonin in the isolated rat bladder. We evaluated the effects of melatonin on the contractions induced by phenylephrine (PE), acetylcholine (ACh), bethanechol (BCh), KCl, and electrical field stimulation (EFS) in 20 detrusor smooth muscle samples from Sprague-Dawley rats. To determine the mechanisms underlying the inhibitory...
