자료유형
발행기관
- 대한생리학회-대한약리학회(30)
- 한국미생물생명공학회(22)
- 한국생물공학회(17)
- 대한수의학회(9)
- 한국환경성돌연변이발암원학회(6)
- 한국식품영양과학회(4)
- 생화학분자생물학회(3)
- 한국미생물학회(3)
- 대한약리학회(2)
- 대한약학회(2)
- 한국응용생명화학회(2)
- 대한구강생물학회(1)
- 대한생리학회(1)
- 대한예방의학회(1)
- 대한치과이식임플란트학회(1)
- 산업안전보건연구원(1)
- 아시아태평양암예방학회(1)
- 한국동물번식학회(1)
- 한국수산과학회(1)
- 한국식물병리학회(1)
- 한국식품과학회(1)
- 한국응용곤충학회(1)
- 환경독성보건학회(1)
간행물
- THE KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY(30)
- JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY(17)
- BIOTECHNOLOGY AND BIOPROCESS ENGINEERING(11)
- JOURNAL OF VETERINARY SCIENCE(8)
- ENVIRONMENTAL MUTAGENS AND CARCINOGENS(6)
- 한국생물공학회지(5)
- 한국미생물-생명공학회지(4)
- JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY(2)
- 대한약리학잡지(2)
- 미생물학회지(2)
- 한국영양식량학회지(2)
- ARCHIVES OF PHARMACAL RESEARCH : A PUBLICATION OF THE PHARMACEUTICAL SOCIETY OF KOREA(1)
- ASIAN PACIFIC JOURNAL OF CANCER PREVENTION : APJCP(1)
- BMB REPORTS(1)
- FISHERIES AND AQUATIC SCIENCES(1)
- INTERNATIONAL JOURNAL OF ORAL BIOLOGY : OFFICIAL JOURNAL OF THE KOREAN ACADEMY OF ORAL BIOLOGY AND T(1)
- JOURNAL OF APPLIED BIOLOGICAL CHEMISTRY(1)
- JOURNAL OF DENTAL IMPLANT RESEARCH(1)
- KSBB JOURNAL(1)
- NUTRACEUTICALS AND FOOD(1)
- SAFETY AND HEALTH AT WORK : SH@W(1)
- THE JOURNAL OF MICROBIOLOGY(1)
- THE PLANT PATHOLOGY JOURNAL (1)
- 대한생리학회지(1)
- 대한수의학회 학술대회발표집(1)
- 산업미생물학회지(1)
- 약학회지(1)
- 예방의학회지(1)
- 한국가축번식학회지(1)
- 한국식품과학회지(1)
- 한국식품영양과학회지(1)
- 한국응용곤충학회지(1)
- 한국응용생명화학회지(1)
- 환경독성학회지(1)
전체 선택해제
총 112건 검색
본문검색 결과만 보기
-
Effect of Low Adapted Temperature and Medium Composition on Growth and Erythropoietin (EPO) Production by Chinese Hamster Ovary Cells
Kim. Na Young, Kim. Jung Hoe, Kim. Hong Jin 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 7 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2005, Vol.28 No.2 220-226 (7 pages)
-
Isolation and Characterization of Endosome Subpopulation in Chinese Hamster Ovarian Cells
Suh, Duk-Joon, Park, Mi-Yeon, Jung, Dong-Keun, Bae, Hae-Rahn 대한생리학회 대한생리학회지 12 Pages
대한생리학회 대한생리학회지 1996, 제 30권 제 2호 2 197-208 (12 pages)
Endosomes lower their internal pH by an ATP-driven proton pump, which is critical to dissociation of many receptor-ligand complexes, the first step in the intracellular sorting of internalized receptors and ligands. Endosomes are known to exhibit n great range of pH values that can vary between 5.0 and 7.0 within a single cell although the factors that regulate endosomal pH remain uncertain. To evaluate the morphological and topological differences of endosomes in the different stages, confocal... -
Reactive oxygen species-mediated unfolded protein response pathways in preimplantation embryos
Ihsan Ali, Syed Zahid Ali Shah, Yi Jin, Zhong-Shu Li, Obaid Ullah, Nan-Zhu Fang 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 1호 1 1-9 (9 pages)
Excessive production of reactive oxygen species (ROS) and endoplasmic reticulum (ER) stress-mediated responses are critical to embryonic development in the challenging in vitro environment. ROS production increases during early embryonic development with the increase in protein requirements for cell survival and growth. The ER is a multifunctional cellular organelle responsible for protein folding, modification, and cellular homeostasis. ER stress is activated by a variety of factors including... -
Establishment and evaluation of a murine ανβ3-integrin- expressing cell line with increased susceptibility to Foot- and-mouth disease virus
Wei Zhang, Kaiqi Lian, Fan Yang, Yang Yang, Zhijian Zhu, Zixiang Zhu, Weijun Cao, Ruoqing Mao, Ye Jin, Jijun He, Jianhong Guo, X 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 3호 3 265-272 (8 pages)
Integrin ανβ3 plays a major role in various signaling pathways, cell apoptosis, and tumor angiogenesis. To examine the functions and roles of ανβ3 integrin, a stable CHO-677 cell line expressing the murine ανβ3 heterodimer (designated as “CHO-677-mανβ3” cells) was established using a highly efficient lentiviral-mediated gene transfer technique. Integrin subunits αν and β3 were detected at the gene and protein levels by polymerase chain reaction (PCR) and indirect... -
Novel insertion mutation of ABCB1 gene in an ivermectin-sensitive Border Collie
Jae-Ik Han, Hyoung-Won Son, Seung-Cheol Park, Ki-Jeong Na* 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2010, 제 11권 제 4호 10 341-344 (4 pages)
P-glycoprotein (P-gp) is encoded by the ABCB1 gene and acts as an efflux pump for xenobiotics. In the Border Collie, a nonsense mutation caused by a 4-base pair deletion in the ABCB1 gene is associated with a premature stop to P-gp synthesis. In this study, we examined the full- length coding sequence of the ABCB1 gene in an ivermectin- sensitive Border Collie that lacked the aforementioned deletion mutation. The sequence was compared to the corresponding sequences of a wild-type Beagle and... -
In vitro and in vivo gene therapy with CMV vector-mediated presumed dog β-nerve growth factor in pyridoxine-induced neuropathy dogs
Jin-Young Chung, Jung-Hoon Choi, Il-Seob Shin, Eun-Wha Choi, Cheol-Yong Hwang, Sang-Koo Lee, Hwa-Young Youn* 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 4호 5 367-374 (8 pages)
Due to the therapeutic potential of gene therapy for neuronal injury, many studies of neurotrophic factors, vectors, and animal models have been performed. The presumed dog β-nerve growth factor (pdβ-NGF) was generated and cloned and its expression was confirmed in CHO cells. The recombinant pdβ-NGF protein reacted with a human β-NGF antibody and showed bioactivity in PC12 cells. The pdβb-NGF was shown to have similar bioactivity to the dog β-NGF. The recombinant pdβ-NGF plasmid was... -
SR144528 as Inverse Agonist of CB2 Cannabinoid Receptor
Man-Hee Rhee and Sang-Keun Kim 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 3호 6 179-184 (6 pages)
It is now well established that several G protein- coupled receptors can signal without agonist stimulation (constitutive receptors). Inverse agonists have been shown to inhibit the activity of such constitutive G protein-coupled receptor signaling. Agonist activation of the G(i/o)-coupled peripheral cannabinoid receptor CB2 normally inhibits adenylyl cyclase type V and stimulates adenylyl cyclase type II. Using transfected COS cells, we show here that application of SR144528, an inverse agonist... -
Antidepressant drug paroxetine blocks the open pore of Kv3.1 potassium channel
HyangMiLee, OkHeeChai, SangJuneHahn, BokHeeChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.1 8 71-80 (10 pages)
expressed in Chinese hamster ovary cells. Paroxetine reversibly reduced the amplitude of Kv3.1 current, with an IC50 value of 9.43 µM and a Hill coefficient of 1.43, and also accelerated the decay of Kv3.1 current. The paroxetine-induced inhibition of Kv3.1 channels was voltage-dependent even when the channels were fully open. The binding (k+1) and unbinding (k–1) rate constants for the paroxetine effect were 4.5 µM–1s–1 and 35.8 s–1, respectively, yielding a...
