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41.

Effects of exercise on obesity-induced mitochondrial dysfunction in skeletal muscle

Jun-WonHeo, Mi-HyunNo, Dong-HoPark, Ju-HeeKang, DaeYunSeo, JinHan, P.DarrellNeufer, Hyo-BumKwak 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.6 1 567-577 (11 pages)

Jun-WonHeo, Mi-HyunNo, Dong-HoPark, Ju-HeeKang, DaeYunSeo, JinHan, P.DarrellNeufer, Hyo-BumKwak 저
...
- 4,000원
Obesity is known to induce inhibition of glucose uptake, reduction of lipid metabolism, and progressive loss of skeletal muscle function, which are all associated with mitochondrial dysfunction in skeletal muscle. Mitochondria are dynamic organelles that regulate cellular metabolism and bioenergetics, including ATP production via oxidative phosphorylation. Due to these critical roles of mitochondria, mitochondrial dysfunction results in various diseases such as obesity and type 2 diabetes....
42.

A Novel Nicotinamide Adenine Dinucleotide Correction Method for Mitochondrial Ca2+ Measurement with FURA-2-FF in Single Permeabilized Ventricular Myocytes of Rat

JeongHoonLee, JeongMiHa, ChaeHunLeem 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.4 10 373-382 (10 pages)

JeongHoonLee, JeongMiHa, ChaeHunLeem 저
...
- 3,000원
carboxy-SNARF-1 for pH were used. With this novel method, we found that the resting mitochondrial [Ca2+] concentration was 1.03 μM. This 1 μM cytosolic Ca2+ could theoretically increase to more than 100 mM in mitochondria. However, the mitochondrial [Ca2+] increase was limited to ∼30 μM in the presence of 1 μM cytosolic Ca2+. Our method solved the problem of NADH signal contamination during the use of Fura-2 analogs, and therefore the method may be useful when NADH interference is expected.
43.

Estrogen Rather Than Progesterone Cause Constipation in Both Female and Male Mice

Ji-EunOh, Yong-WoonKim, So-YoungPark, Jong-YeonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.5 7 423-426 (4 pages)

Ji-EunOh, Yong-WoonKim, So-YoungPark, Jong-YeonKim 저
...
- 1,500원
Females are more often affected by constipation than males, especially during pregnancy, which is related to the menstrual cycle. Although still controversial, alterations of progesterone and estrogen may be responsible. Therefore, this study was conducted in order to determine whether the female sex steroid hormone itself is responsible for development of constipation in both female and male mice. Administration of estrogen resulted in a decrease in weight of accumulated feces on days 2, 3, 4,...
44.

A Review on Renal Toxicity Profile of Common Abusive Drugs

VarunParkashSingh, NirmalSingh, AmteshwarSinghJaggi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.4 13 347-357 (11 pages)

VarunParkashSingh, NirmalSingh, AmteshwarSinghJaggi 저
...
- 4,000원
a major social problem of the modern world and majority of these abusive drugs or their metabolites are excreted through the kidneys and, thus, the renal complications of these drugs are very common. Morphine, heroin, cocaine, nicotine and alcohol are the most commonly abused drugs, and their use is associated with various types of renal toxicity. The renal complications include a wide range of glomerular, interstitial and vascular diseases leading to acute or chronic renal failure. The present...
45.

Pretreatment of Albino Rats with Methanolic Fruit Extract of Randia Dumetorum (L.) Protects against Alcohol Induced Liver Damage

ArshadAliNoorani, MohanK.Kale 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.2 7 125-130 (6 pages)

ArshadAliNoorani, MohanK.Kale 저
...
- 3,000원
a major health problem in many areas of the world. The present study was conducted to evaluate the protective effect of methanolic fruit extract of Randia dumetorum (L.) on alcohol-induced liver damage in rats. Rats were divided into five different groups (n=6), group I served as a control, group II received ethanol (3 ml/100 g/day p.o.), group III served as standard group and received silymarin (50 mg/kg p.o.), group IV and V served as extract treatment groups and received 50 & 100 mg/kg...
46.

Modulation of Pituitary Somatostatin Receptor Subtype (sst1-5) mRNA Levels by Growth Hormone (GH)-Releasing Hormone in Purified Somatotropes

SeungjoonPark, HeesoonPark, MinaLee, SookjinSohn, EunheeKim, JeechangJung, LawrenceA.Frohman, RhondaD.Kineman 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.2 5 79-84 (6 pages)

SeungjoonPark, HeesoonPark, MinaLee, SookjinSohn, EunheeKim, JeechangJung, LawrenceA.Frohman, RhondaD.Kineman 저
...
- 3,000원
We have previously reported that expression of the somatostatin receptor subtypes, sst1-5, is differentially regulated by growth hormone (GH)-releasing hormone (GHRH) and forskolin (FSK), in vitro. GHRH binds to membrane receptors selectively located on pituitary somatotropes, activates adenylyl cyclase (AC) and increases sst1 and sst2 and decreases sst5 mRNA levels, without significantly altering the expression of sst3 and sst4. In contrast FSK directly activates AC in all pituitary cell types...
47.

The Staging of Major Mood Disorders

Ather Muneer, Rana Mazommil 대한신경정신의학회 Psychiatry Investigation 12 Pages

대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 2 747-758 (12 pages)

Ather Muneer, Rana Mazommil 저
...
- 4,100원
Objective_Staging of psychiatric disorders is gaining momentum and the purpose of this review is to examine whether major mood disorders can be defined according to stages. Methods_In April 2018 the PubMed electronic data base was scrutinized by a combination of various search terms like “major depressive disorder and staging,” “bipolar disorder and neuroprogression,” etc. To incorporate the latest findings the search was limited to the last 10 years. Both original and review articles were...
48.

청소년에서 폭력에의 노출과 관련된 정신의학적 증상

이호분, 민성길, 전여숙, 송동호, 육기환, 김동기 대한신경정신의학회 신경정신의학 10 Pages

대한신경정신의학회 신경정신의학 1998, 제 37권 제 2호 6 251-260 (10 pages)

이호분, 민성길, 전여숙, 송동호, 육기환, 김동기 저
...
- 3,000원
서울 시내 중학생 1345명을 대상으로 폭력에 노출되는 정도와 이와 연관된 정신의학적 증상을 알아보고 자 하였다. 이를 위해 자기보고식 설문지를 사용하였는데, 설문지의 내용은 사회인구학적 자료와 집, 학교, 동네에서 폭력을 당하거나 목격했는지를 묻는 문항과 폭력에 의한 정신의학적 증상의 정도를 묻는 TSC(trauma symptom checklist)로 구성되었으며, 그 결과는 다음과 같다. 1) 전체 학생 중 45%가 폭력에 노출된 경험이 있었으며, 남자가 여자보다 많았다(p<0.025). 집에서 구타 당한 경험은 여학생이 22.8%로 남학생보다...
49.

월경 전기 변화 여성에서 월경 전기 증상의 양상과 스트레스 대처 방식

류영민, 조숙행 대한신경정신의학회 신경정신의학 11 Pages

대한신경정신의학회 신경정신의학 2000, 제 39권 제 6호 9 1061-1071 (11 pages)

류영민, 조숙행 저
...
- 4,000원
연구배경： 월경 전기 변화의 원인으로써 많은 가설들이 제시되어 왔는데, 이중에 환경적인 스트레스와 월경 전기 변 화의 관련성에 관한 보고가 있다. 즉, 월경 전기 변화를 보이는 여성은 스트레스 상황에서 그것을 평가하고 대처하는 양식이 월경 전기 변화를 유발하거나 악화시킬 수 있다. 이에 본 연구에서는 정상 성인 여성에서 월경 전기 변화군을 선별하여, 월경 전기 변화의 증상 양상과 스트레스 대처 방식 사이의 연관성을 알아보고 자 하였다. 방 법： 고려대학교 부속 의료원과 부산 동인 병원의 간호사 및 직원과 그 가족...
50.

애착장애 아동에서 99m-Tc-ECD-SPECT로 측정한 뇌혈류량의 양상

천근아, 이경숙, 신의진 대한신경정신의학회 신경정신의학 11 Pages

대한신경정신의학회 신경정신의학 2001, 제 40권 제 1호 10 98-108 (11 pages)

천근아, 이경숙, 신의진 저
...
- 4,000원
연구목적： 아동 학대 또는 방치와 같은 병적인 양육환경이 신경생물학적인 변화를 야기할 수 있다는 가정 하에, 심각 한 주양육자와의 애착관계의 문제를 보이는 아동들을 대상으로 SPECT를 이용한 뇌 혈류 양상을 알아보고 뇌의 비정상 소견 여부를 관찰하고자 한다. 방 법： 연구대상은 반응성애착장애(reactive attachment disorder)로 진단된 2∼6세 아동 12명으로 구성되었다. 진단도구로서 DSM-IV, ICD-10, 낯선상황절차(Strange Situation Procedure), 사회성숙도 검사(Social Maturity Scale), 아동기 자폐증 평가척도(Childhood...

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