학지사 뉴논문

총 171건 검색

본문검색 결과만 보기

정확도순

최신순

등재순

발행기간

전체
최근 1년
최근 3년
직접입력

적용하기

본문검색

포함

제외

10개씩

41.

Phellodendron amurense and Its Major Alkaloid Compound, Berberine Ameliorates Scopolamine-Induced Neuronal Impairment and Memory Dysfunction in Rats

BombiLee, BongjunSur, InsopShim, HyejungLee, Dae-HyunHahm 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.2 1 79-89 (11 pages)

BombiLee, BongjunSur, InsopShim, HyejungLee, Dae-HyunHahm 저
...
- 4,000원
We examine whether Phellodendron amurense (PA) and its major alkaloid compound, berberine (BER), improved memory defects caused by administering scopolamine in rats. Effects of PA and BER on the acetylcholinergic system and pro-inflammatory cytokines in the hippocampus were also investigated. Male rats were administered daily doses for 14 days of PA (100 and 200 mg/kg, i.p.) and BER (20 mg/kg, i.p.) 30 min before scopolamine injection (2 mg/kg, i.p.). Daily administration of PA and BER improved...
42.

Effects of Isoflurane Anesthesia on Post-Anesthetic Sleep-Wake Architectures in Rats

Hwan-SooJang, Ji-YoungJung, Kwang-HoJang, Maan-GeeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.5 7 291-297 (7 pages)

Hwan-SooJang, Ji-YoungJung, Kwang-HoJang, Maan-GeeLee 저
...
- 3,000원
The sleep homeostatic response significantly affects the state of anesthesia. In addition, sleep recovery may occur during anesthesia, either via a natural sleep-like process to occur or via a direct restorative effect. Little is known about the effects of isoflurane anesthesia on sleep homeostasis. We investigated whether 1) isoflurane anesthesia could provide a sleep-like process, and 2) the depth of anesthesia could differently affect the post-anesthesia sleep response. Nine rats were treated...
43.

Modulation of Large Conductance Ca2+-activated K+ Channel of Skin Fibroblast (CRL-1474) by Cyclic Nucleotides

JihyunYun, SeungtaeKim, HyoweonBang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.2 9 131-134 (4 pages)

JihyunYun, SeungtaeKim, HyoweonBang 저
...
- 1,500원
Potassium channels in human skin fibroblast have been studied as a possible site of Alzheimer disease pathogenesis. Fibroblasts in Alzheimer disease show alterations in signal transduction pathway such as changes in Ca2⁢ homeostasis and/or Ca2⁢-activated kinases, phosphatidylinositol cascade, protein kinase C activity, cAMP levels and absence of specific K⁢ channel. However, little is known so far about electrophysiological and pharmacological characteristics of...
44.

Modulation of Pituitary Somatostatin Receptor Subtype (sst1-5) mRNA Levels by Growth Hormone (GH)-Releasing Hormone in Purified Somatotropes

SeungjoonPark, HeesoonPark, MinaLee, SookjinSohn, EunheeKim, JeechangJung, LawrenceA.Frohman, RhondaD.Kineman 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.2 5 79-84 (6 pages)

SeungjoonPark, HeesoonPark, MinaLee, SookjinSohn, EunheeKim, JeechangJung, LawrenceA.Frohman, RhondaD.Kineman 저
...
- 3,000원
We have previously reported that expression of the somatostatin receptor subtypes, sst1-5, is differentially regulated by growth hormone (GH)-releasing hormone (GHRH) and forskolin (FSK), in vitro. GHRH binds to membrane receptors selectively located on pituitary somatotropes, activates adenylyl cyclase (AC) and increases sst1 and sst2 and decreases sst5 mRNA levels, without significantly altering the expression of sst3 and sst4. In contrast FSK directly activates AC in all pituitary cell types...
45.

Nitroxergic Nerve Relaxes Rat Gastric Smooth Muscle by NO-cGMP Pathway

YoongSamYoon, HyoungChulChoi, YoungSookJung, JongHoKim, KwangYounLee, UyDongSohn, JeoungHeeHa, WonJoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.5 5 369-378 (10 pages)

YoongSamYoon, HyoungChulChoi, YoungSookJung, JongHoKim, KwangYounLee, UyDongSohn, JeoungHeeHa, WonJoonKim 저
...
- 3,000원
This study was undertaken to investigate an involvement of nitroxergic innervation in gastric smooth muscle of rat. Isometric tension study, the measurement of single cell length, NADPH diaphorase stain of smooth muscle layers and neuronal nitric oxide synthase (nNOS) western blotting were performed. Sodium nitroprusside (SNP), a nitric oxide donor, relaxed the muscle strips precontracted by acetylcholine (ACh) in a concentration-dependent manner. Pretreatment of L-arginine decreased the...
46.

Thyroid Hormone-Induced Alterations of Ca2+-ATPase and Phospholamban Protein Expression in Cardiac Sarcoplasmic Reticulum

HaeWonKim, KyungMinNoh, MiyoungPark, HeeRanLee, EunHeeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.2 13 223-230 (8 pages)

HaeWonKim, KyungMinNoh, MiyoungPark, HeeRanLee, EunHeeLee 저
...
- 3,000원
Alterations of cardiovascular function associated with various thyroid states have been studied. In hyperthyroidism left ventricular contractility and relaxation velocity were increased, whereas these parameters were decreased in hypothyroidism. The mechanisms for these changes have been suggested to include alterations in the expression and/or activity levels of various proteins; α-myosin heavy chain, β- myosin heavy chain, β-receptors, the guanine nucleotide-binding regulatory protein, and...
47.

Lipocortin 1 Mediates the Suppressive Effects of Dexamethasone on ConA-induced Proliferative Response and Nitric Oxide Production in Rat Splenic Leukocytes

YeonJinJang, HyoungsupPark, SoonAKang, SusJungYang, DoeSunNa 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.1 12 91-96 (6 pages)

YeonJinJang, HyoungsupPark, SoonAKang, SusJungYang, DoeSunNa 저
...
- 3,000원
Lipocortin 1 has been proposed as a putative mediator of anti-inflammatory actions of glucocorticoids. We investigated the role of lipocortin 1 in the effect of dexamethasone using rat splenic leukocytes. Concanavalin A(ConA; 1 ㄍg/ml) increased the leukocyte proliferation and nitric oxide(NO) generation, which were measured as [3H]-thymidine uptake by the cells and nitrite accumulation in the culture media, respectively. Dexamethasone suppressed ConA-induced cell proliferation, in a...
48.

DSM-III-R 주요우울증에 대한 한국어판 Geriatric Depression Scale(GDS)의 진단적 타당성 연구

조맹제, 배재남, 서국희, 함봉진, 김장규, 이동우, 강민희 대한신경정신의학회 신경정신의학 16 Pages

대한신경정신의학회 신경정신의학 1999, 제 38권 제 1호 4 48-63 (16 pages)

조맹제, 배재남, 서국희, 함봉진, 김장규, 이동우, 강민희 저
...
- 4,500원
연구목적： 본 연구는 노인성 우울증의 선별 검사도구로 전세계적으로 널리 사용되고 있는 Geriatric Deression Scale(GDS) 및 축약형 GDS(SGDS)가 우리나라에서도 타당성 있게 사용될 수 있는지 평가하기 위한 것 이다. 방 법： 3차례의 예비연구 과정을 거쳐서 우울증 선별 검사도구인 한국판 GDS을 제작한 후에, 88명의 임상환자군 을 대상으로 한국판 GDS의 신뢰도와 타당도 검증, 주요우울증의 선별을 위한 최적절단점 추정, ROC커브 를 이용한 진단적 타당성 분석을 하였으며, 15문항의 한국판 SGDS에 대한 표준화 연구도 아울러...
49.

主要憂戀症환자 예비평가에서 the Center for Epidemiologic Studies Depression Scale(CES-D) 의 진단적 타당성 연구

조맹제, 김계회 대한신경정신의학회 신경정신의학 19 Pages

대한신경정신의학회 신경정신의학 1993, 제 32권 제 3호 11 381-399 (19 pages)

조맹제, 김계회 저
...
- 4,800원
50.

自然產物精神病藥劑의 Dopamine-2 및 Serotonin-2 受容體結合

鄭寅元, 金承律, 金應國 대한신경정신의학회 신경정신의학 13 Pages

대한신경정신의학회 신경정신의학 1992, 제 31권 제 5호 4 856-868 (13 pages)

鄭寅元, 金承律, 金應國 저
...
- 4,200원

한주간 이슈검색어