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611.

Determination of Roxithromycin by Liquid Chromatography/ Mass Spectrometry after Multiple-Dose Oral Administration in Broilers

Jong-hwan Lim, Byung-kwon Park, Hyo-in Yun 대한수의학회 Journal of Veterinary Science 5 Pages

대한수의학회 Journal of Veterinary Science 2003, 제 4권 제 1호 6 35-39 (5 pages)

Jong-hwan Lim, Byung-kwon Park, Hyo-in Yun 저
...
- 1,500원
A highly sensitive and specific method for the determination of roxithromycin in broiler tissues by LC/MS was developed and validated. A dichloromethane extract of the sample was separated on C18 reversed-phase column with acetonitrile-50 mM ammonium acetate (80:20, v/v) as the mobile phase and analyzed by LC/MS via atmospheric pressure ionization/electrospray ionization interface. The limit of detection and limit of quantitation were 1 ng/g and 5 ng/g. The method has been successfully applied...
612.

Effects of Tributyltin Chloride on the Reproductive System in Pubertal Male Rats

Wook-joon Yu, Sang-yoon Nam, Young-chul Kim, Beom-jun Lee, Young-won Yun 대한수의학회 Journal of Veterinary Science 6 Pages

대한수의학회 Journal of Veterinary Science 2003, 제 4권 제 1호 5 29-34 (6 pages)

Wook-joon Yu, Sang-yoon Nam, Young-chul Kim, Beom-jun Lee, Young-won Yun 저
...
- 3,000원
Detrimental effects of tributyltin (TBT) chloride on the reproductive system were investigated in pubertal male rats. Sixty Sprague-Dawley rats aged with 35 days were assigned to six different groups; negative control receiving vehicle, positive control receiving methyltestosterone (10 mg/kg B.W.), TBT chloride (5 mg/kg B.W., 10 mg/kg B.W., and 20 mg/kg B.W.), and a combination of TBT chloride (10 mg/kg B.W.) and flutamide (10 mg/kg B.W). The animals were treated with test compounds by oral...
613.

An immunohistochemical Study on the Pancreatic Endocrine Cells of the C57BL/6 Mouse

Sae-Kwang Ku, Hyeung-Sik Lee and Jae-Hyun Lee 대한수의학회 Journal of Veterinary Science 7 Pages

대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 4호 11 327-333 (7 pages)

Sae-Kwang Ku, Hyeung-Sik Lee and Jae-Hyun Lee 저
...
- 3,000원
The regional distribution and relative frequency of the pancreatic endocrine cells in the C57BL/6 mouse were studied by immunohistochemical method using four types of specific mammalian antisera against insulin, glucagon, somatostatin and human pancreatic polypeptide (PP). The pancreas of mouse could be divided into three portions; pancreatic islets, pancreatic duct and exocrine portions, and pancreatic islets were further subdivided into three regions (central, mantle and peripheral regions)...
614.

Requirement of Metabolic Activation for Estrogenic Activity of Pueraria mirifica

Y.S. Lee, J.S. Park, S.D. Cho, J.K. Son, W. Cherdshewasart and K.S. Kang 대한수의학회 Journal of Veterinary Science 5 Pages

대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 4호 4 273-277 (5 pages)

Y.S. Lee, J.S. Park, S.D. Cho, J.K. Son, W. Cherdshewasart and K.S. Kang 저
...
- 1,500원
A wide range of chemicals derived from plant and human-made xenobiotics are reported to have hormonal activities. The present study was performed to examine the estrogenic effect of Kwao Keur, Pueraria mirifica (PM), that has been used as a rejuvenating folk medicine in Thailand, using recombinant yeast, MCF-7 cell proliferation and HepG2 cell transient transfection assay. In recombinant yeast assay, 0.025, 0.25, 2.5, 25, 2.5 x 10(2), 2.5 x 10(3), 2.5 x 10(4) ng/ml concentrations of PM did not...
615.

Frequencies of Micronuclei in Peripheral Lymphocytes in Korean Populations after Chronic Low-dose Radiation Exposure

Mi-Young An and Tae-Hwan Kim 대한수의학회 Journal of Veterinary Science 6 Pages

대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 3호 11 213-218 (6 pages)

Mi-Young An and Tae-Hwan Kim 저
...
- 3,000원
The purpose of this study was to estimate predictive markers of intrinsic radiosensitivity in individuals who were exposed to occupational or environmental radiation. Throughout this process, the actual biohazard risks and base-line chromosome damage were evaluated in human population. Further studies were carried out to provide evidence for the existence of individual variations in age-dependent responses through micronuclei (MN) assay. Spontaneous frequencies not only vary greatly between...
616.

Effects of Electroacupuncture on Minimum Alveolar Concentration of Isoflurane and Cardiovascular System in Isoflurane Anesthetized Dogs

Seong-Mok Jeong 대한수의학회 Journal of Veterinary Science 9 Pages

대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 3호 8 193-201 (9 pages)

Seong-Mok Jeong 저
...
- 3,000원
The effects of electroacupuncture (EA) on the minimum alveolar concentration (MAC) and on the cardiovascular system were evaluated with dogs under isoflurane anesthesia. Eight healthy male beagles were randomly assigned to six study groups (five heads/group) with washout intervals of 7 ~ 31 days between experiments for recovery and anesthetic clearance. MAC of isoflurane and cardiovascular parameters were determined after EA at nonacupoint and and at acupoints LI-4, SP-6, ST-36 and TH-8....
617.

Functional Role of Serine Residues of Transmembrane Dopamin VII in Signal Transduction of CB2 Cannabinoid Receptor

Man-Hee Rhee 대한수의학회 Journal of Veterinary Science 7 Pages

대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 3호 7 185-191 (7 pages)

Man-Hee Rhee 저
...
- 3,000원
Using site-directed mutagenesis technique, I have replaced serine 285 and serine 292 with the alanine, and assessed the binding of agonist and signaling such as the inhibition of adenylyl cyclase activity. I have found that serine 292 has an important role in the signal transduction of cannabinoid agonists, HU-210 and CP55940, but not in that of aminoalkylindoles derivatives WIN55,212-2. All mutants express well in protein level determined by western blot using monoclonal antibody HA 11 as...
618.

Immunological Responses of Dogs Experimentally Infectedwith Dirofilaria immitis

Kun-Ho Song, Mineo Hayasaki, Chusnul Choliq, Kyu-Woan Cho, Hong-Ryul Han, Bung-Hyun Jeong, Moo-Hyung Jeon, Bae-Kun Parkand Duck-Hwa 대한수의학회 Journal of Veterinary Science 6 Pages

대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 2호 8 109-114 (6 pages)

Kun-Ho Song, Mineo Hayasaki, Chusnul Choliq, Kyu-Woan Cho, Hong-Ryul Han, Bung-Hyun Jeong, Moo-Hyung Jeon, Bae-Kun Parkand Duck-Hwa 저
...
- 3,000원
immunoblotting methods. Antibody titers of dogs detected by ELISA peaked between 7 and 14 weeks then decreased between weeks 15 to 24 followed by another increase during weeks 25 to 30 and persisted throughout the remainder of the experiment period. Analysis of adult D. immitis protein stained with Coomassie brilliant blue R-250 indicated separately more than 10 bands, and the major bands were 22, 40, 46, 56, 70, 72 and 89 kDa. Antigenic identification of extracts antigens of adults D. immitis b...
619.

Simultaneous Determination of Various Macrolides by Liquid Chromatography/Mass Spectrometry

Youn-Hwan Hwang, Jong-Hwan Lim, Byung-Kwon Park and Hyo-In Yun 대한수의학회 Journal of Veterinary Science 6 Pages

대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 2호 7 103-108 (6 pages)

Youn-Hwan Hwang, Jong-Hwan Lim, Byung-Kwon Park and Hyo-In Yun 저
...
- 3,000원
Macrolides are frequently used in veterinary medicine as therapeutic and preventive agents for various diseases. It is difficult to determine macrolides simultaneously with conventional methods due to their similar structures. A simultaneous analysis for erythromycin, roxithromycin, tiamulin and tylosin with LC/MS has been developed. Separation was performed on C18 reversed phase column. Mobile phase was gradiently flowed with 10 mM ammonium acetate and methanol. The mass spectrometer was run in...
620.

Assessment of Replication and Virulence of Attenuated Pseudorabies Virus in Swine

T. J. Newby, D. P. Carter, K.-J. Yoon, M. W. Jackwood and P. A. Hawkins 대한수의학회 Journal of Veterinary Science 6 Pages

대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 2호 1 61-66 (6 pages)

T. J. Newby, D. P. Carter, K.-J. Yoon, M. W. Jackwood and P. A. Hawkins 저
...
- 3,000원
A nonclinical study was conducted to characterize the replication behavior of a modified live gE-deleted pseudorabies virus (PRV MS) in swine and potential for reversion to virulence after animal passages. Two to 3 week-old weaned pigs, negative for PRV, were maintained in isolation and challenged by intranasal instillation. For the first passage, 6 pigs were given 1 mL of PRV MS (10(7.3)TCID(50)/mL) and 2 were necropsied at 3, 4 and 5 days post-inoculation (PI). Brain and secondary lymphoid...

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