학지사 뉴논문

총 269건 검색

본문검색 결과만 보기

정확도순

최신순

등재순

발행기간

전체
최근 1년
최근 3년
직접입력

적용하기

본문검색

포함

제외

10개씩

61.

Disposition kinetics and urinary excretion of ciprofloxacin in goats following single intravenous administration

R. Raina, S. Prawez*, D.J. Dimitrova, N.K. Pankaj, P.K. Verma 대한수의학회 Journal of Veterinary Science 6 Pages

대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 3호 3 241-246 (6 pages)

R. Raina, S. Prawez*, D.J. Dimitrova, N.K. Pankaj, P.K. Verma 저
...
- 3,000원
mg/kg body weight. The serum concentration-time curves of ciprofloxacin were best fitted by a two-compartment open model. The drug was detected in goat serum up to 12 h. The elimination rate constant (b) and elimination half-life (t1/2b) were 0.446 ± 0.04 h and 1.630 ± 0.17 h, respectively. The apparent volume of distribution at steady state (Vdss) was 2.012 ± 0.37 l/kg and the total body clearance (ClB) was 16.27 ± 1.87 ml/min/kg. Urinary recovery of ciprofloxacin was 29.70%...
62.

Effect of trikatu pretreatment on the pharmacokinetics of pefloxacin administered orally in mountain Gaddi goats

Madhukar S. Dama, C. Varshneya, *, M. S. Dardi, V. C. Katoch3 대한수의학회 Journal of Veterinary Science 5 Pages

대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 1호 4 25-29 (5 pages)

Madhukar S. Dama, C. Varshneya, *, M. S. Dardi, V. C. Katoch3 저
...
- 1,500원
a decreased plasma concentration (p > 0.05) of pefloxacin following trikatu administration during the absorption phase (10, 15, 20 min post pefloxacin administration). In contrast, the plasma concentrations of pefloxacin were significantly higher at 4, 6, 8 and 12 h (during the elimination phase) of the pefloxacin administration. The findings of the investigation revealed higher values for the area under the curve, the area under the first moment of the plasma drug concentration time curve, the...
63.

Antimicrobial susceptibility and molecular detection of chloramphenicol and florfenicol resistance among Escherichia coli isolates from diseased chickens

Xin-Sheng Li, Gui-Qin Wang, Xiang-Dang Du, Bao-An Cui, Su-Mei Zhang, Jian-Zhong Shen 대한수의학회 Journal of Veterinary Science 5 Pages

대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 3호 7 243-247 (5 pages)

Xin-Sheng Li, Gui-Qin Wang, Xiang-Dang Du, Bao-An Cui, Su-Mei Zhang, Jian-Zhong Shen 저
...
- 1,500원
Seventy Escherichia coli isolates recovered from diseased chickens diagnosed with colibacillosis in Henan Province, China, between 2004 and 2005 were characterized for antimicrobial susceptibility profiles via a broth doubling dilution method. Overall, the isolates displayed resistance to trimethoprim-sulfamethoxazole (100%), oxytetracycline (100%), ampicillin (83%), enrofloxacin (83%), and ciprofloxacin (81%), respectively. Among the phenicols, resistance was approximately 79% and 29% for...
64.

Disposition kinetics and urinary excretion of cefpirome after intravenous injection in buffalo calves

Neetu Rajput, Vinod K. Dumka, Harpal S. Sandhu 대한수의학회 Journal of Veterinary Science 5 Pages

대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 1호 4 21-25 (5 pages)

Neetu Rajput, Vinod K. Dumka, Harpal S. Sandhu 저
...
- 1,500원
1 min after injection, the concentration of cefpirome in the plasma was 57.4 ± 0.72 μg/ml, which declined to 0.22 ± 0.01 μg/ml at 24 h. The cefpirome was rapidly distributed from the blood to the tissue compartment as shown by the high distribution coefficient values (8.67 ± 0.46/h), and by the drug’s rate of transfer constant from the central to the peripheral compartment, K12 (4.94 ± 0.31/h). The elimination halflife and the volume of distribution were 2.14 ± 0.02 h and 0.42 ± 0.005...
65.

Pharmacokinetics, urinary excretion and dosage regimen of levofloxacin following a single intramuscular administration in cross bred calves

Vinod K. Dumka, Anil K. Srivastava 대한수의학회 Journal of Veterinary Science 5 Pages

대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 4호 5 333-337 (5 pages)

Vinod K. Dumka, Anil K. Srivastava 저
...
- 1,500원
seven male cross bred calves. Appreciable plasma concentration of levofloxacin (0.38 ± 0.06 μg/ml) was detected at 1 min after injection and the peak plasma level of 3.07 ± 0.08 μg/ml was observed at 1 h. The drug level above MIC90 in plasma was detected up to 12 h after administration. Rapid absorption of the drug was also evident by the high value of the absorption rate constant (2.14 ± 0.24 /h). The overall systemic bioavailability of levofloxacin, after intramuscular administration, was...
66.

Pharmacokinetics and bioavailability of doxycycline in ostriches (Struthio camelus) at two different dose rates

Ehab A. Abu-Basha, Nasir M. Idkaidek, Tareq M. Hantash 대한수의학회 Journal of Veterinary Science 6 Pages

대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 4호 4 327-332 (6 pages)

Ehab A. Abu-Basha, Nasir M. Idkaidek, Tareq M. Hantash 저
...
- 3,000원
respectively. The absolute bioavailability (F) of doxycycline was 5.03 and 17.52% after oral and IM administration, respectively. These results show that the dose data from other animals particularly mammals cannot be extrapolated to ostriches. Therefore, based on these results along with those reported in the literature, further studies on the pharmacokinetic/ pharmacodynamic, in vitro minimum inhibitory concentration values and clinical applications of doxycycline in ostriches are required.
67.

Influence of endotoxin induced fever on the pharmacokinetics of intramuscularly administered cefepime in rabbits

Ayman Goudah, Samar M. Mouneir, Jae-Han Shim, A. M. Abd El-Aty 대한수의학회 Journal of Veterinary Science 5 Pages

대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 2호 10 151-155 (5 pages)

Ayman Goudah, Samar M. Mouneir, Jae-Han Shim, A. M. Abd El-Aty 저
...
- 1,500원
This study examined the effect of experimentally induced fever on the pharmacokinetics of cefepime (75 mg/kg BW) administered intramuscularly to six rabbits. The study was carried out in two consecutive phases separated by a two-week washout period. An infection was induced by an intravenous inoculation of 5 × 108 colony-forming units of Escherichia coli 24 h before the pharmacokinetic investigation. A quantitative microbiological assay was employed to measure the plasma cefepime concentrations...
68.

Subcutaneous pharmacokinetics and dosage regimen of cefotaxime in buffalo calves (Bubalus bubalis)

Suresh Kumar Sharma, Anil Kumar Srivastava 대한수의학회 Journal of Veterinary Science 4 Pages

대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 2호 4 119-122 (4 pages)

Suresh Kumar Sharma, Anil Kumar Srivastava 저
...
- 1,500원
The pharmacokinetics and dosage regimen of cefotaxime following its single subcutaneous administration (10 mg/ kg) were investigated in buffalo calves. Plasma and urine samples were collected over 10 and 24 h post administration, respectively. Cefotaxime in plasma and urine was estimated by microbiological assay technique using E. coli as test organism. The pharmacokinetic profiles fitted one-compartment open model. The peak plasma levels of cefotaxime were 6.48 ± 0.52 ?g/ml at 30 min and the...
69.

Alteration of pharmacokinetics of oxytetracycline following oral administration of Piper longum in hens

M. Singh, C. Varshneya, R. S. Telang, A. K. Srivastava 대한수의학회 Journal of Veterinary Science 4 Pages

대한수의학회 Journal of Veterinary Science 2005, 제 6권 제 3호 4 197-200 (4 pages)

M. Singh, C. Varshneya, R. S. Telang, A. K. Srivastava 저
...
- 1,500원
plasma levels of OTC against time were adequately described by one compartment open model. The pharmacokinetic data revealed that P.longum treated animals had significantly higher area under curve (AUC), area under the first moment of plasma drug concentration-time curve (AUMC)and mean residential time (MRT). Prior treatment of P.longum significantly reduced elimination rate constan(&bgr;)and increased elimination half life (t1/2&bgr;). The total body clearance (ClB) reduced by 21%whereas total...
70.

Pharmacokinetics and dosage regimen of ceftriaxone in E. coli lipopolysaccharide induced fever in buffalo calves

Manmohan Singh Dardi, Suresh Kumar Sharma, Anil Kumar Srivastava 대한수의학회 Journal of Veterinary Science 4 Pages

대한수의학회 Journal of Veterinary Science 2005, 제 6권 제 2호 9 147-150 (4 pages)

Manmohan Singh Dardi, Suresh Kumar Sharma, Anil Kumar Srivastava 저
...
- 1,500원
min, the peak concentration of ceftriaxone was 79.4 ± 2.37 μg/ml and the drug was detected up to 6 h. The elimination rate constant was 0.35 ± 0.02 /h and elimination half-life was 2.04 ± 0.14 h. The apparent volume of distribution (Vd(area )) and total body clearance (ClB) were 1.21 ± 0.15 l/kg and 0.41 ± 0.03 l/kg/h, respectively. To maintain a minimum therapeutic concentration of 1 μg/ kg, a satisfactory dosage regimen of cefriaxone in febrile buffalo calves is 19 mg/kg followed by 18...

한주간 이슈검색어